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The map label for this gene is 108763303

Identifier: 108763303

GI number: 108763303

Start: 4612120

End: 4614267

Strand: Reverse

Name: 108763303

Synonym: MXAN_3837

Alternate gene names: NA

Gene position: 4614267-4612120 (Counterclockwise)

Preceding gene: 108763908

Following gene: 108760468

Centisome position: 50.49

GC content: 70.44

Gene sequence:

>2148_bases
ATGGAGTTGCGCAAGCTCAAGGACAAGGCGTCCGAGGCATTCACCAAGGGACGCTTTTCCAAGGCGGCGGAGCTCTACGA
GGACTACTGCCGGGCCGAGCCCAAGGACCATCAGTCACGCCTGCGCTCCGGGGATGCCTGGGTGAAGGCGGGGCAACGGG
ACCGGGCCATCTCGGCGTATCAATCCGCCGCGGAAGGCTTCGCGCGCGAGGGGTTCCTTCCGCGCGCCATCGCCGCGAGC
AAGCTCATCCTCGAGCTGGACCCCGCGCACCGTGGCGTGCAGCAGATGCTCGCGGACCTGTACGCGCGCCGGGGAACGCC
CATGGGCGCACGTGCCCGGGGCCCGATGAGCAGCGCGTCGTCCGTGACGGTGAAGACGTCCTCCGAGCCTGCTGGGGCGT
CGCGTCTGCCCGAGGCAGTGCGCGCGGCCGTCGCCGCCATTGATTTGGGGGAGAGGGGGGAGGGTGCTTCGCCAGCCCCG
TTGGCGGCTGGTGGTCCCGCGGTGGACCTGTCTGCGGAGCTGCCTCCAGAGCTGTCGTTGTCCACCAACGCGTCCACGCG
TGGCACCGAAGAAGTCGTCCACTCGGTCGAGGTAGGACTGGCGTCGGAAGAGGGGACCGCTGGCGTGGAGTTGACGCTGG
ACGTGGAGCCCGTCGTGGCAGGGACGCTGGTGGACGACGCGTGTGGAACCGATTCGATGACGTCCGAATTGGCCACGTCT
GTCGAGGCATCCACGATCGTGGCGGCCTCAATCCCGCCCGCGATGGCCCTCCGTGAGCCAGAAGCGCCGCCGCTCGCGAC
CCGGATTCCCGCGGTTCAACCCGGAGGCGCGCGTCCGGCGACGAGTGCGTTGCCGCCAGGACTGGCACCGCGCGCGTCGC
AGCGGCTGCCCGCGGTGGGCGCTGCTCGCGCGCCCGAACCCGCGCCGTCCGCACCGCCACGGTCCGTCTCGAACAGCGGC
CGCTGGCAAGCCCTGTCGTCGCCCATCACCACGCAGGCAGCGCCCGCAGCTTCTGAAGCCGCGGCCGCCTCCGCGCCCCC
AGGACTGCGGGCGCGCCGTGCCGACCCACCGGTCCCCGCGGGCGCCACCGCGCTCCCGGGCCACGACCTGTCACCCGCGC
TGGGCGCCTCCTTCCGGACGGCGGCGAGTCCGTCCTCCTTCACCGAGTTGGAGCTGGAAGCCGACTCCCTGTTGCACGCG
GTGGAGCTGGCCGCGCAGGCGGGCTTGGATCGGCAAGGCCTGGGGGCCACGTCCATCAGCGACGGCCTCGAGGAGGAGCT
CTACAGCCTGACGGAGGAGGTCCCTCCCGACGCGGGTTCCCTGGACGCGCTGCCCACGATTCCGCTCTTCTCGGACCTGC
CTCGCGACGCCTTCATCGAGCTGTTCGAGCGCTGCCCGCTGCGGCGCTTCGGCCCGGACGAGCGAATCATCGACCAGGGC
AGCCACGGCGATGCTTTCTACGTCATCTGCGAGGGCGCGGTGCGCGTCTTCCGGACGGAGGAGGGCCAGCGCCAGGACAT
CGCGACGCTCGAAGGAGGCACCTTCTTCGGAGAGATGGCCCTGCTGTCCGGCGCGGCGCGCACGGCCTCGGTGGAGTCCG
CGTCCGACGACACCCAGCTCCTGGAGATCTCCGCCAGCGTGCTCGCCGAGCTCTCGGGAAGCCACCCGCAGGTGGCCCAG
GCCCTGAAGAAGTTCTGCCGTCAGCGCATGCTGACGAACGTGATGAACACGTCGGAGCTGTTCCGCCTCTTCGGGCGAAA
GGACCGGCGCGCGCTCGTGGAGCGCTTCCGCTCCCGGGACGTGGAGCGTGACACCGTCATCATCCGTGACGGCGACCCGA
CGGACGGCCTCTATGTGGTCCTGTCCGGCGAGGTGGAGGTGCGCAAGGACGGCCACCTGCTGACGCAGCTCCGGGAAGGG
GACGTGTTCGGAGAGATTTCCCTGCTCCAGAAGACGCCTGCCACCGCGACCGTCACCGCCACCCGGCACACCACGCTGCT
GCGGTTGCCGCGCGCCGACTTCGACGCGCTCATCTCCAGCCACCCGCAAATCCTGGCCCTGATCTCCGACCTGAGCGACG
AACGGCTCCGGCGCACGCAGCGCGTGCTGACCGAAGCCGGCGTCGAGGAAGACCTCATCCTCGTCTGA

Upstream 100 bases:

>100_bases
ACCAGTTGGAGGCCCTCAAGGCGGACTACTTCCGGACGGTGCGTGAGGCCGCGGGCGCGGCACCGGCGTCCGCGAGCACC
GCGTCGGAGGGCGCTCCCTG

Downstream 100 bases:

>100_bases
CGTCAGCGCACCTTGGCGAGGTAGTCGTCTCGCGTCACCAGGCCGCGCGTCTCCAGGAGCTCCAGCATGGCCCGCAGCGA
GCGGGCCTGCTGGGCCACCA

Product: cyclic nucleotide-binding domain-containing protein

Products: NA

Alternate protein names: MscS Mechanosensitive Ion Channel; CAMP-Dependent Protein Kinase

Number of amino acids: Translated: 715; Mature: 715

Protein sequence:

>715_residues
MELRKLKDKASEAFTKGRFSKAAELYEDYCRAEPKDHQSRLRSGDAWVKAGQRDRAISAYQSAAEGFAREGFLPRAIAAS
KLILELDPAHRGVQQMLADLYARRGTPMGARARGPMSSASSVTVKTSSEPAGASRLPEAVRAAVAAIDLGERGEGASPAP
LAAGGPAVDLSAELPPELSLSTNASTRGTEEVVHSVEVGLASEEGTAGVELTLDVEPVVAGTLVDDACGTDSMTSELATS
VEASTIVAASIPPAMALREPEAPPLATRIPAVQPGGARPATSALPPGLAPRASQRLPAVGAARAPEPAPSAPPRSVSNSG
RWQALSSPITTQAAPAASEAAAASAPPGLRARRADPPVPAGATALPGHDLSPALGASFRTAASPSSFTELELEADSLLHA
VELAAQAGLDRQGLGATSISDGLEEELYSLTEEVPPDAGSLDALPTIPLFSDLPRDAFIELFERCPLRRFGPDERIIDQG
SHGDAFYVICEGAVRVFRTEEGQRQDIATLEGGTFFGEMALLSGAARTASVESASDDTQLLEISASVLAELSGSHPQVAQ
ALKKFCRQRMLTNVMNTSELFRLFGRKDRRALVERFRSRDVERDTVIIRDGDPTDGLYVVLSGEVEVRKDGHLLTQLREG
DVFGEISLLQKTPATATVTATRHTTLLRLPRADFDALISSHPQILALISDLSDERLRRTQRVLTEAGVEEDLILV

Sequences:

>Translated_715_residues
MELRKLKDKASEAFTKGRFSKAAELYEDYCRAEPKDHQSRLRSGDAWVKAGQRDRAISAYQSAAEGFAREGFLPRAIAAS
KLILELDPAHRGVQQMLADLYARRGTPMGARARGPMSSASSVTVKTSSEPAGASRLPEAVRAAVAAIDLGERGEGASPAP
LAAGGPAVDLSAELPPELSLSTNASTRGTEEVVHSVEVGLASEEGTAGVELTLDVEPVVAGTLVDDACGTDSMTSELATS
VEASTIVAASIPPAMALREPEAPPLATRIPAVQPGGARPATSALPPGLAPRASQRLPAVGAARAPEPAPSAPPRSVSNSG
RWQALSSPITTQAAPAASEAAAASAPPGLRARRADPPVPAGATALPGHDLSPALGASFRTAASPSSFTELELEADSLLHA
VELAAQAGLDRQGLGATSISDGLEEELYSLTEEVPPDAGSLDALPTIPLFSDLPRDAFIELFERCPLRRFGPDERIIDQG
SHGDAFYVICEGAVRVFRTEEGQRQDIATLEGGTFFGEMALLSGAARTASVESASDDTQLLEISASVLAELSGSHPQVAQ
ALKKFCRQRMLTNVMNTSELFRLFGRKDRRALVERFRSRDVERDTVIIRDGDPTDGLYVVLSGEVEVRKDGHLLTQLREG
DVFGEISLLQKTPATATVTATRHTTLLRLPRADFDALISSHPQILALISDLSDERLRRTQRVLTEAGVEEDLILV
>Mature_715_residues
MELRKLKDKASEAFTKGRFSKAAELYEDYCRAEPKDHQSRLRSGDAWVKAGQRDRAISAYQSAAEGFAREGFLPRAIAAS
KLILELDPAHRGVQQMLADLYARRGTPMGARARGPMSSASSVTVKTSSEPAGASRLPEAVRAAVAAIDLGERGEGASPAP
LAAGGPAVDLSAELPPELSLSTNASTRGTEEVVHSVEVGLASEEGTAGVELTLDVEPVVAGTLVDDACGTDSMTSELATS
VEASTIVAASIPPAMALREPEAPPLATRIPAVQPGGARPATSALPPGLAPRASQRLPAVGAARAPEPAPSAPPRSVSNSG
RWQALSSPITTQAAPAASEAAAASAPPGLRARRADPPVPAGATALPGHDLSPALGASFRTAASPSSFTELELEADSLLHA
VELAAQAGLDRQGLGATSISDGLEEELYSLTEEVPPDAGSLDALPTIPLFSDLPRDAFIELFERCPLRRFGPDERIIDQG
SHGDAFYVICEGAVRVFRTEEGQRQDIATLEGGTFFGEMALLSGAARTASVESASDDTQLLEISASVLAELSGSHPQVAQ
ALKKFCRQRMLTNVMNTSELFRLFGRKDRRALVERFRSRDVERDTVIIRDGDPTDGLYVVLSGEVEVRKDGHLLTQLREG
DVFGEISLLQKTPATATVTATRHTTLLRLPRADFDALISSHPQILALISDLSDERLRRTQRVLTEAGVEEDLILV

Specific function: Unknown

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4758958, Length=249, Percent_Identity=24.8995983935743, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI47132583, Length=286, Percent_Identity=27.6223776223776, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI47132581, Length=286, Percent_Identity=27.6223776223776, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI4506063, Length=286, Percent_Identity=27.6223776223776, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI258613977, Length=219, Percent_Identity=27.8538812785388, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI258613975, Length=219, Percent_Identity=27.8538812785388, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI258613973, Length=219, Percent_Identity=27.8538812785388, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI258613971, Length=219, Percent_Identity=27.8538812785388, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI258613969, Length=219, Percent_Identity=27.8538812785388, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI38257139, Length=219, Percent_Identity=27.8538812785388, Blast_Score=69, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994934, Length=218, Percent_Identity=28.8990825688073, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534999, Length=218, Percent_Identity=28.8990825688073, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI133901990, Length=218, Percent_Identity=28.8990825688073, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25145047, Length=269, Percent_Identity=28.996282527881, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17539610, Length=269, Percent_Identity=28.996282527881, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17539608, Length=269, Percent_Identity=28.996282527881, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71989393, Length=269, Percent_Identity=28.996282527881, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322156, Length=213, Percent_Identity=28.6384976525822, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI161076492, Length=226, Percent_Identity=27.8761061946903, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28573932, Length=226, Percent_Identity=27.8761061946903, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28573930, Length=226, Percent_Identity=27.8761061946903, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17647815, Length=226, Percent_Identity=27.8761061946903, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI161076490, Length=226, Percent_Identity=27.8761061946903, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24667745, Length=287, Percent_Identity=27.5261324041812, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI62472332, Length=287, Percent_Identity=27.5261324041812, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI62472322, Length=287, Percent_Identity=27.5261324041812, Blast_Score=74, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28574658, Length=287, Percent_Identity=27.5261324041812, Blast_Score=74, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221513359, Length=287, Percent_Identity=27.5261324041812, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI62472300, Length=290, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI62472310, Length=290, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28574654, Length=290, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28574656, Length=290, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI62472279, Length=290, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI62472291, Length=290, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 75485; Mature: 75485

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3 ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRKLKDKASEAFTKGRFSKAAELYEDYCRAEPKDHQSRLRSGDAWVKAGQRDRAISAY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCHHHHHHH
QSAAEGFAREGFLPRAIAASKLILELDPAHRGVQQMLADLYARRGTPMGARARGPMSSAS
HHHHHHHHHCCCCHHHHHHHHEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SVTVKTSSEPAGASRLPEAVRAAVAAIDLGERGEGASPAPLAAGGPAVDLSAELPPELSL
EEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCEE
STNASTRGTEEVVHSVEVGLASEEGTAGVELTLDVEPVVAGTLVDDACGTDSMTSELATS
CCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEHHHHHCCCCCCHHHHHHHHH
VEASTIVAASIPPAMALREPEAPPLATRIPAVQPGGARPATSALPPGLAPRASQRLPAVG
HHHHEEEEECCCCHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCC
AARAPEPAPSAPPRSVSNSGRWQALSSPITTQAAPAASEAAAASAPPGLRARRADPPVPA
CCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCC
GATALPGHDLSPALGASFRTAASPSSFTELELEADSLLHAVELAAQAGLDRQGLGATSIS
CCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCCHHH
DGLEEELYSLTEEVPPDAGSLDALPTIPLFSDLPRDAFIELFERCPLRRFGPDERIIDQG
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCCCHHHHCCC
SHGDAFYVICEGAVRVFRTEEGQRQDIATLEGGTFFGEMALLSGAARTASVESASDDTQL
CCCCEEEEEECCCHHEEECCCCCCCCCEEECCCCHHHHHHHHHCCHHHCCCCCCCCCHHH
LEISASVLAELSGSHPQVAQALKKFCRQRMLTNVMNTSELFRLFGRKDRRALVERFRSRD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
VERDTVIIRDGDPTDGLYVVLSGEVEVRKDGHLLTQLREGDVFGEISLLQKTPATATVTA
CCCCEEEEECCCCCCCEEEEEECCEEEECCCHHHHHHHCCCCCEEHHHHHCCCCCEEEEE
TRHTTLLRLPRADFDALISSHPQILALISDLSDERLRRTQRVLTEAGVEEDLILV
CCCEEEEECCCCCHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEC
>Mature Secondary Structure
MELRKLKDKASEAFTKGRFSKAAELYEDYCRAEPKDHQSRLRSGDAWVKAGQRDRAISAY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCHHHHHHH
QSAAEGFAREGFLPRAIAASKLILELDPAHRGVQQMLADLYARRGTPMGARARGPMSSAS
HHHHHHHHHCCCCHHHHHHHHEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SVTVKTSSEPAGASRLPEAVRAAVAAIDLGERGEGASPAPLAAGGPAVDLSAELPPELSL
EEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCEE
STNASTRGTEEVVHSVEVGLASEEGTAGVELTLDVEPVVAGTLVDDACGTDSMTSELATS
CCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEHHHHHCCCCCCHHHHHHHHH
VEASTIVAASIPPAMALREPEAPPLATRIPAVQPGGARPATSALPPGLAPRASQRLPAVG
HHHHEEEEECCCCHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCC
AARAPEPAPSAPPRSVSNSGRWQALSSPITTQAAPAASEAAAASAPPGLRARRADPPVPA
CCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCC
GATALPGHDLSPALGASFRTAASPSSFTELELEADSLLHAVELAAQAGLDRQGLGATSIS
CCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCCHHH
DGLEEELYSLTEEVPPDAGSLDALPTIPLFSDLPRDAFIELFERCPLRRFGPDERIIDQG
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCCCHHHHCCC
SHGDAFYVICEGAVRVFRTEEGQRQDIATLEGGTFFGEMALLSGAARTASVESASDDTQL
CCCCEEEEEECCCHHEEECCCCCCCCCEEECCCCHHHHHHHHHCCHHHCCCCCCCCCHHH
LEISASVLAELSGSHPQVAQALKKFCRQRMLTNVMNTSELFRLFGRKDRRALVERFRSRD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
VERDTVIIRDGDPTDGLYVVLSGEVEVRKDGHLLTQLREGDVFGEISLLQKTPATATVTA
CCCCEEEEECCCCCCCEEEEEECCEEEECCCHHHHHHHCCCCCEEHHHHHCCCCCEEEEE
TRHTTLLRLPRADFDALISSHPQILALISDLSDERLRRTQRVLTEAGVEEDLILV
CCCEEEEECCCCCHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA