Click here to switch to the map view.

The map label for this gene is nuoG [H]

Identifier: 108763204

GI number: 108763204

Start: 3177576

End: 3179201

Strand: Reverse

Name: nuoG [H]

Synonym: MXAN_2728

Alternate gene names: 108763204

Gene position: 3179201-3177576 (Counterclockwise)

Preceding gene: 108758426

Following gene: 108761566

Centisome position: 34.78

GC content: 68.82

Gene sequence:

>1626_bases
GTGGTGAAGCCGGGGACGAACATGATCGAGGCGGCCAAGGCGGTCGGCTCGGACATCCCCTACTACTGCTACCACCCGCG
CCTCTCCATCGCGGCCAACTGCCGCATCTGCCTCATCGAGGCGTCCAACGCGCCCAAGATGGTGCCCGCGTGCCAGACGC
CCATGGCCGAAGGCCAGGTCGTCAAGACGACCACGCCCAAGGTGAAGGAGCAGCAGCGCGCGGTGATGGAGTTCCTGCTG
CTGAACCACCCGGTCGACTGCTCCATCTGCGACCAGGCCGGTGAGTGCAAGCTGCAGGACTACTACATGAAGTACGACTA
CCGGCCCTCGCGCCTGGAGGGCACCAAGGCCCTCAAGAACAAGCGCAAGGTGCTGGGGCCCCGCGTCGTCATCGACCAGG
AGCGCTGCATCATGTGCACCCGCTGCGTGCGCGTGATGAACGAGGTGGCCAAGGAGCCGCAGCTGGGCGTGTTCGGCCGC
GGCAGCCACGAGCGCATCGACGTGTTCCCGGGCAGCGAGCTGAACAGCAACTACTCGCTCAACACCGTGGACGTGTGCCC
GGTGGGCGCGCTGCTCAGCCGCGACTTCCGCTTCAAGGCGCGCGCGTGGTTCCTGTCCGCCACCCCGTCGGTGTGCACCG
GCTGCTCGCGCGGCTGCACCACCTACGTGGACTGGATGTCGCAGGACTCGTACCGCTACCGCCCGCGGGAGAACGAGGCC
ATCAACAAGAGCTGGATGTGCGACGAGGGCCGGCTCACCTACAAGTACCTGAACCTGGGCCGCGTGCTCCAGGCGCAGGT
GGGCCGCCGCACCAACCGCGCCGGTGAGGCGGTGCCCGTCACCACGCGCAAGGAAGCGGTCCAGGCCGCGGCCAAGGCGC
TGCGCTCGGTGCAGGGCAGCAAGCAGCTGGCGGTGCTGGCCTCGCCCCTGGCCTCCAACGAGGACCTGCTGGCCGGGCTG
AACTTCGCCAAGAGCACGCTGGGCGTGTCCACCGTGTACGTGGGCGGCCGTCCTTCGGGCTCCGCCGACCACTTCCTGAT
GACGGCGGACAAGAACCCCAACCGCAAGGGCCTGGAGCTCATTGCGAAGGGGCTGGGCCTCAAGCTGGAGACCTTCGACG
CGCTCACCACCGCGCTGAAGGCGGGAACGGTGAAGGCGCTCTACGCCATCGGCACCGAGGTGCCGGGCAACGTGGACGCC
TTCGCGGAGGCCGCGGGTCAGCTGGACGTGTTCGTGGCGCAGGCCTTCACCGAGTCCGCCATCACCGCGCAGGCCACGGT
GCTGCTGCCGGCCTCCGTCCCCGTCGAGGACGAGGGCTCGTTCGTGCAGCAGGACGGCATCATCCAGCGCTTCCGCAAGG
CGTACCCGCCCAAGGGCGACGTCGTCCCCGGCTGGGAGTGGGTCAGGGAGCTGACGCGCGAGTTGGGTGGCGAGTCCACC
TGGAAGCGCGCCGTCGACGTATGGCGCGAGCTGGCTGGCAAGGTGGCCGAGTTCGCGGAGTTCAACTGGGAGAAGGCGTC
TCCGGCGGACCGGGAGAAGCCGGGCATCAATCCGCTGCCGGCAGGTGCCGACGGTCGCCCCGCGGGGTACCGTGAGTTCG
GCACGCCTCGGGTGAGGGGTATCTAG

Upstream 100 bases:

>100_bases
CACGGGGACGCCGCCGCCCAAGCCGCCCTCCGGCCCGCCGCCCAAGCCGGCGCCGAAGAACCCGGGGTTCATCACCGCCA
CCATCGACGGCAAGGAAGTC

Downstream 100 bases:

>100_bases
TCATGAGCCGCGTACTGACGATTCTCGTCGCCATGTTCACCATCGTCTTCCTGATGGCGGGTGGCATGGCGTCGGCCTAC
CTCGTGGGTGGCCTGGTGGA

Product: putative NADH dehydrogenase I subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MVKPGTNMIEAAKAVGSDIPYYCYHPRLSIAANCRICLIEASNAPKMVPACQTPMAEGQVVKTTTPKVKEQQRAVMEFLL
LNHPVDCSICDQAGECKLQDYYMKYDYRPSRLEGTKALKNKRKVLGPRVVIDQERCIMCTRCVRVMNEVAKEPQLGVFGR
GSHERIDVFPGSELNSNYSLNTVDVCPVGALLSRDFRFKARAWFLSATPSVCTGCSRGCTTYVDWMSQDSYRYRPRENEA
INKSWMCDEGRLTYKYLNLGRVLQAQVGRRTNRAGEAVPVTTRKEAVQAAAKALRSVQGSKQLAVLASPLASNEDLLAGL
NFAKSTLGVSTVYVGGRPSGSADHFLMTADKNPNRKGLELIAKGLGLKLETFDALTTALKAGTVKALYAIGTEVPGNVDA
FAEAAGQLDVFVAQAFTESAITAQATVLLPASVPVEDEGSFVQQDGIIQRFRKAYPPKGDVVPGWEWVRELTRELGGEST
WKRAVDVWRELAGKVAEFAEFNWEKASPADREKPGINPLPAGADGRPAGYREFGTPRVRGI

Sequences:

>Translated_541_residues
MVKPGTNMIEAAKAVGSDIPYYCYHPRLSIAANCRICLIEASNAPKMVPACQTPMAEGQVVKTTTPKVKEQQRAVMEFLL
LNHPVDCSICDQAGECKLQDYYMKYDYRPSRLEGTKALKNKRKVLGPRVVIDQERCIMCTRCVRVMNEVAKEPQLGVFGR
GSHERIDVFPGSELNSNYSLNTVDVCPVGALLSRDFRFKARAWFLSATPSVCTGCSRGCTTYVDWMSQDSYRYRPRENEA
INKSWMCDEGRLTYKYLNLGRVLQAQVGRRTNRAGEAVPVTTRKEAVQAAAKALRSVQGSKQLAVLASPLASNEDLLAGL
NFAKSTLGVSTVYVGGRPSGSADHFLMTADKNPNRKGLELIAKGLGLKLETFDALTTALKAGTVKALYAIGTEVPGNVDA
FAEAAGQLDVFVAQAFTESAITAQATVLLPASVPVEDEGSFVQQDGIIQRFRKAYPPKGDVVPGWEWVRELTRELGGEST
WKRAVDVWRELAGKVAEFAEFNWEKASPADREKPGINPLPAGADGRPAGYREFGTPRVRGI
>Mature_541_residues
MVKPGTNMIEAAKAVGSDIPYYCYHPRLSIAANCRICLIEASNAPKMVPACQTPMAEGQVVKTTTPKVKEQQRAVMEFLL
LNHPVDCSICDQAGECKLQDYYMKYDYRPSRLEGTKALKNKRKVLGPRVVIDQERCIMCTRCVRVMNEVAKEPQLGVFGR
GSHERIDVFPGSELNSNYSLNTVDVCPVGALLSRDFRFKARAWFLSATPSVCTGCSRGCTTYVDWMSQDSYRYRPRENEA
INKSWMCDEGRLTYKYLNLGRVLQAQVGRRTNRAGEAVPVTTRKEAVQAAAKALRSVQGSKQLAVLASPLASNEDLLAGL
NFAKSTLGVSTVYVGGRPSGSADHFLMTADKNPNRKGLELIAKGLGLKLETFDALTTALKAGTVKALYAIGTEVPGNVDA
FAEAAGQLDVFVAQAFTESAITAQATVLLPASVPVEDEGSFVQQDGIIQRFRKAYPPKGDVVPGWEWVRELTRELGGEST
WKRAVDVWRELAGKVAEFAEFNWEKASPADREKPGINPLPAGADGRPAGYREFGTPRVRGI

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=319, Percent_Identity=40.4388714733542, Blast_Score=233, Evalue=2e-61,
Organism=Escherichia coli, GI145693161, Length=341, Percent_Identity=31.9648093841642, Blast_Score=179, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI32566231, Length=322, Percent_Identity=39.4409937888199, Blast_Score=225, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17565758, Length=322, Percent_Identity=39.4409937888199, Blast_Score=224, Evalue=9e-59,
Organism=Caenorhabditis elegans, GI193209088, Length=245, Percent_Identity=42.4489795918367, Blast_Score=201, Evalue=9e-52,
Organism=Drosophila melanogaster, GI24640559, Length=271, Percent_Identity=39.1143911439114, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24640557, Length=271, Percent_Identity=39.1143911439114, Blast_Score=214, Evalue=1e-55,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 59306; Mature: 59306

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS00641 COMPLEX1_75K_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKPGTNMIEAAKAVGSDIPYYCYHPRLSIAANCRICLIEASNAPKMVPACQTPMAEGQV
CCCCCCHHHHHHHHHCCCCCEEEECCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCCEE
VKTTTPKVKEQQRAVMEFLLLNHPVDCSICDQAGECKLQDYYMKYDYRPSRLEGTKALKN
EECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHH
KRKVLGPRVVIDQERCIMCTRCVRVMNEVAKEPQLGVFGRGSHERIDVFPGSELNSNYSL
HHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEECCCCCCCCCCCC
NTVDVCPVGALLSRDFRFKARAWFLSATPSVCTGCSRGCTTYVDWMSQDSYRYRPRENEA
CEEECCCCHHHHCCCCCEEEEEEEEECCCHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCC
INKSWMCDEGRLTYKYLNLGRVLQAQVGRRTNRAGEAVPVTTRKEAVQAAAKALRSVQGS
CCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCC
KQLAVLASPLASNEDLLAGLNFAKSTLGVSTVYVGGRPSGSADHFLMTADKNPNRKGLEL
CCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCCCHHHHHH
IAKGLGLKLETFDALTTALKAGTVKALYAIGTEVPGNVDAFAEAAGQLDVFVAQAFTESA
HHHHCCCEEHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
ITAQATVLLPASVPVEDEGSFVQQDGIIQRFRKAYPPKGDVVPGWEWVRELTRELGGEST
HHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHH
WKRAVDVWRELAGKVAEFAEFNWEKASPADREKPGINPLPAGADGRPAGYREFGTPRVRG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCC
I
C
>Mature Secondary Structure
MVKPGTNMIEAAKAVGSDIPYYCYHPRLSIAANCRICLIEASNAPKMVPACQTPMAEGQV
CCCCCCHHHHHHHHHCCCCCEEEECCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCCEE
VKTTTPKVKEQQRAVMEFLLLNHPVDCSICDQAGECKLQDYYMKYDYRPSRLEGTKALKN
EECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHH
KRKVLGPRVVIDQERCIMCTRCVRVMNEVAKEPQLGVFGRGSHERIDVFPGSELNSNYSL
HHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEECCCCCCCCCCCC
NTVDVCPVGALLSRDFRFKARAWFLSATPSVCTGCSRGCTTYVDWMSQDSYRYRPRENEA
CEEECCCCHHHHCCCCCEEEEEEEEECCCHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCC
INKSWMCDEGRLTYKYLNLGRVLQAQVGRRTNRAGEAVPVTTRKEAVQAAAKALRSVQGS
CCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCC
KQLAVLASPLASNEDLLAGLNFAKSTLGVSTVYVGGRPSGSADHFLMTADKNPNRKGLEL
CCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCCCHHHHHH
IAKGLGLKLETFDALTTALKAGTVKALYAIGTEVPGNVDAFAEAAGQLDVFVAQAFTESA
HHHHCCCEEHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
ITAQATVLLPASVPVEDEGSFVQQDGIIQRFRKAYPPKGDVVPGWEWVRELTRELGGEST
HHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHH
WKRAVDVWRELAGKVAEFAEFNWEKASPADREKPGINPLPAGADGRPAGYREFGTPRVRG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA