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The map label for this gene is nuoH [H]

Identifier: 108761566

GI number: 108761566

Start: 3176125

End: 3177573

Strand: Reverse

Name: nuoH [H]

Synonym: MXAN_2727

Alternate gene names: 108761566

Gene position: 3177573-3176125 (Counterclockwise)

Preceding gene: 108763204

Following gene: 108758967

Centisome position: 34.77

GC content: 67.15

Gene sequence:

>1449_bases
ATGAGCCGCGTACTGACGATTCTCGTCGCCATGTTCACCATCGTCTTCCTGATGGCGGGTGGCATGGCGTCGGCCTACCT
CGTGGGTGGCCTGGTGGAGGAGCACTGGTTCACTGGCGCGAGCCGGCTGACCAACGTGCTGTTCCTCGTCCTCATCTTCG
TGATGGTCATCGCCACGCTGCTGACCATGGCGGAGCGCAAGTGGAGCGCGTTCATCCAGGACCGCATGGGTCCCAACCGC
GCCCGCATCGCCCTGCCCGGCCTGAAGAACCGCCCGCTGGGCGGCCTTCCGCACATCCTCACGGACGTGCTGAAGATGCT
GACCAAGGAAGACCTGATTCCGGCCGCCGCGAACCGGTTCATGTTCAACCTGGGCCCCATCCTGGCCTTCGCGCCCACCT
TCGCCCTGTTCGCCGTGGTGCCCGCCGGTCCGTCGGTGCAGGTGTTCGGCCGCAATGTGGACATGGTGGTGGCCACGCCG
GACTTCGGCGCCCTCTACGTGCTCGCCATCGCCTCGCTGGCCGTCTACGGCACCGCGCTGGCCGGCTGGGCCTCCAACAA
CAAGTTCGGCCTGCTGGGCGGCGTGCGCGCCACCTCGCAGATGATCGCCTACGAGGTCGCGCTCGGCCTGTCCCTGGTCG
GCATCTTCCTCACGTTCTCCTCGGTGCAGTTCCCGGCCATCATTGGTGACATCGGCAACGCGCTCACCGGCGGCACCGGA
CAGGGCCGCTACCTGTGGCGCACGGACGGCGCCTTCGACCTGGGGCTGCCCGCGTGGGGCATCTTCATCCAGCCGCTGGG
CTTCCTGCTCTTCTTCGCCGCGTCCTTCGCGGAGACCAAGCGCGCCCCGTTCGACCTGCCGGAAGGCGAGTCGGAGATCA
TCGGCTACTTCGTTGAGTACTCCGGCATGAAGTTCGGCCTCTTCATGATCTCCGAGTTCGTGGAGGTCGTGGTGCTGGCC
GGCGTGACGACAGCGTTCTTCTTCGGCGGCTACCACCTGCCCTTCGGCAACGAGTGGCTGGCCAACCTGCCCATCATGCA
GGAGCACGGCTGGCTGCTGGGCACCATCCTGGGCACGGTGTTCTGGCTGAAGGTGCTGTTCCTCATCTGGGTGCAGCTGC
TCATCCGCTGGACGTTCCCCCGCTTCCGCTACGACCAGATTCAGTCGCTGGGCTGGAAGATCCTCCTCCCCCTCGGCCTG
GTGAACGTGTTCGTGACGGGTGCGCTGGTCCTCTGGGATCCGTCCCTGCGGGCGCTCGCGGTCCTCGGCATCGCGGAGAT
TGGTATCCTGGTGGTGTTGACCACGACGACGAAGGTCCCCGCAGGCGGTGCGCACGGGGCGCACGCCGGCCATGGTCACG
ACCACGGACATGGCCACGCCCACGGTGGGCACGGTGCCCATGACCTGCCGGCGCACGCCCACGGCGTGGCCCCGGCCTCC
ACCCACTAG

Upstream 100 bases:

>100_bases
ACCGGGAGAAGCCGGGCATCAATCCGCTGCCGGCAGGTGCCGACGGTCGCCCCGCGGGGTACCGTGAGTTCGGCACGCCT
CGGGTGAGGGGTATCTAGTC

Downstream 100 bases:

>100_bases
GCCGCCCCTTTCGGCCCCAGCATCCGGGAATCGAGAACCATCATGGCCTACAAGGTAAGCAAGGACCCTCGCACGGATAT
CCGCGAGCGGACCTATGTGC

Product: putative NADH dehydrogenase I subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MSRVLTILVAMFTIVFLMAGGMASAYLVGGLVEEHWFTGASRLTNVLFLVLIFVMVIATLLTMAERKWSAFIQDRMGPNR
ARIALPGLKNRPLGGLPHILTDVLKMLTKEDLIPAAANRFMFNLGPILAFAPTFALFAVVPAGPSVQVFGRNVDMVVATP
DFGALYVLAIASLAVYGTALAGWASNNKFGLLGGVRATSQMIAYEVALGLSLVGIFLTFSSVQFPAIIGDIGNALTGGTG
QGRYLWRTDGAFDLGLPAWGIFIQPLGFLLFFAASFAETKRAPFDLPEGESEIIGYFVEYSGMKFGLFMISEFVEVVVLA
GVTTAFFFGGYHLPFGNEWLANLPIMQEHGWLLGTILGTVFWLKVLFLIWVQLLIRWTFPRFRYDQIQSLGWKILLPLGL
VNVFVTGALVLWDPSLRALAVLGIAEIGILVVLTTTTKVPAGGAHGAHAGHGHDHGHGHAHGGHGAHDLPAHAHGVAPAS
TH

Sequences:

>Translated_482_residues
MSRVLTILVAMFTIVFLMAGGMASAYLVGGLVEEHWFTGASRLTNVLFLVLIFVMVIATLLTMAERKWSAFIQDRMGPNR
ARIALPGLKNRPLGGLPHILTDVLKMLTKEDLIPAAANRFMFNLGPILAFAPTFALFAVVPAGPSVQVFGRNVDMVVATP
DFGALYVLAIASLAVYGTALAGWASNNKFGLLGGVRATSQMIAYEVALGLSLVGIFLTFSSVQFPAIIGDIGNALTGGTG
QGRYLWRTDGAFDLGLPAWGIFIQPLGFLLFFAASFAETKRAPFDLPEGESEIIGYFVEYSGMKFGLFMISEFVEVVVLA
GVTTAFFFGGYHLPFGNEWLANLPIMQEHGWLLGTILGTVFWLKVLFLIWVQLLIRWTFPRFRYDQIQSLGWKILLPLGL
VNVFVTGALVLWDPSLRALAVLGIAEIGILVVLTTTTKVPAGGAHGAHAGHGHDHGHGHAHGGHGAHDLPAHAHGVAPAS
TH
>Mature_481_residues
SRVLTILVAMFTIVFLMAGGMASAYLVGGLVEEHWFTGASRLTNVLFLVLIFVMVIATLLTMAERKWSAFIQDRMGPNRA
RIALPGLKNRPLGGLPHILTDVLKMLTKEDLIPAAANRFMFNLGPILAFAPTFALFAVVPAGPSVQVFGRNVDMVVATPD
FGALYVLAIASLAVYGTALAGWASNNKFGLLGGVRATSQMIAYEVALGLSLVGIFLTFSSVQFPAIIGDIGNALTGGTGQ
GRYLWRTDGAFDLGLPAWGIFIQPLGFLLFFAASFAETKRAPFDLPEGESEIIGYFVEYSGMKFGLFMISEFVEVVVLAG
VTTAFFFGGYHLPFGNEWLANLPIMQEHGWLLGTILGTVFWLKVLFLIWVQLLIRWTFPRFRYDQIQSLGWKILLPLGLV
NVFVTGALVLWDPSLRALAVLGIAEIGILVVLTTTTKVPAGGAHGAHAGHGHDHGHGHAHGGHGAHDLPAHAHGVAPAST
H

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=354, Percent_Identity=29.9435028248588, Blast_Score=135, Evalue=1e-31,
Organism=Escherichia coli, GI1788618, Length=366, Percent_Identity=35.2459016393443, Blast_Score=209, Evalue=4e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 51893; Mature: 51761

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS00668 COMPLEX1_ND1_2 ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVLTILVAMFTIVFLMAGGMASAYLVGGLVEEHWFTGASRLTNVLFLVLIFVMVIATL
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LTMAERKWSAFIQDRMGPNRARIALPGLKNRPLGGLPHILTDVLKMLTKEDLIPAAANRF
HHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
MFNLGPILAFAPTFALFAVVPAGPSVQVFGRNVDMVVATPDFGALYVLAIASLAVYGTAL
HHHHHHHHHHHHHHHHHEEECCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
AGWASNNKFGLLGGVRATSQMIAYEVALGLSLVGIFLTFSSVQFPAIIGDIGNALTGGTG
HCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
QGRYLWRTDGAFDLGLPAWGIFIQPLGFLLFFAASFAETKRAPFDLPEGESEIIGYFVEY
CCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHEEC
SGMKFGLFMISEFVEVVVLAGVTTAFFFGGYHLPFGNEWLANLPIMQEHGWLLGTILGTV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHCCCCHHHCCHHHHHHHHHH
FWLKVLFLIWVQLLIRWTFPRFRYDQIQSLGWKILLPLGLVNVFVTGALVLWDPSLRALA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEHHHHHHHHHHHCEEEEECCCHHHHH
VLGIAEIGILVVLTTTTKVPAGGAHGAHAGHGHDHGHGHAHGGHGAHDLPAHAHGVAPAS
HHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TH
CC
>Mature Secondary Structure 
SRVLTILVAMFTIVFLMAGGMASAYLVGGLVEEHWFTGASRLTNVLFLVLIFVMVIATL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LTMAERKWSAFIQDRMGPNRARIALPGLKNRPLGGLPHILTDVLKMLTKEDLIPAAANRF
HHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
MFNLGPILAFAPTFALFAVVPAGPSVQVFGRNVDMVVATPDFGALYVLAIASLAVYGTAL
HHHHHHHHHHHHHHHHHEEECCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
AGWASNNKFGLLGGVRATSQMIAYEVALGLSLVGIFLTFSSVQFPAIIGDIGNALTGGTG
HCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
QGRYLWRTDGAFDLGLPAWGIFIQPLGFLLFFAASFAETKRAPFDLPEGESEIIGYFVEY
CCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHEEC
SGMKFGLFMISEFVEVVVLAGVTTAFFFGGYHLPFGNEWLANLPIMQEHGWLLGTILGTV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHCCCCHHHCCHHHHHHHHHH
FWLKVLFLIWVQLLIRWTFPRFRYDQIQSLGWKILLPLGLVNVFVTGALVLWDPSLRALA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEHHHHHHHHHHHCEEEEECCCHHHHH
VLGIAEIGILVVLTTTTKVPAGGAHGAHAGHGHDHGHGHAHGGHGAHDLPAHAHGVAPAS
HHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TH
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA