Click here to switch to the map view.

The map label for this gene is frr

Identifier: 108761597

GI number: 108761597

Start: 6649837

End: 6650394

Strand: Reverse

Name: frr

Synonym: MXAN_5341

Alternate gene names: 108761597

Gene position: 6650394-6649837 (Counterclockwise)

Preceding gene: 108762561

Following gene: 108760505

Centisome position: 72.76

GC content: 63.62

Gene sequence:

>558_bases
ATGAGTGGAGACGTCGTCGCCGAACTGAAGGGCCGTATCGACAAATCGCTCGAGGGCCTGCGCACGGACCTGACGAGGGT
CCGCACGGGCCGCGCCAGCATCGCCATCCTGGAGGGCGTCCGGGTGGACTACTACGGCACGCCGACGCCGCTGTCGGGCG
TGGCCAGCGTGAACGCGCCCGAGCCCCGGCTCATCACCATCAAGCCGTGGGAGAAGAGCGTCCTCAAGGACATCGAGAAG
GCGCTGCGCGAGGCGAACCTGGGCATCAACCCGATGAACGACGGCGAGATGATTCGCCTGCCCTTCCCGCCGCTCACTGA
AGAGCGCCGCAAGGACATCGCCAAGCAGGTGAAGACCAAGGGCGAGGAGTTCAAGGTCACCATCCGCAACCTCCGCCGCG
ACGCGAACGAGGTGCTGAAGACGCAGCTGAAGGACAAGAAGATCACCGAGGACGACCACAAGCGCATCACCGAGGTCGTG
CAGAAGCAGACCGACGCGGGCATCACGCAGGTGGATGAAATCGTGAAGAAGAAGGAGAAGGAGGTCATGGAGGTTTGA

Upstream 100 bases:

>100_bases
CGGTGCTGGGTGAAGGGGACATTGGTACGTTGGTGGGTGGCAGCGAGACGGTCTGGGCCTGAGTCCCGACCCACCGGCAA
GCACTCAAGGAGAGAACGCA

Downstream 100 bases:

>100_bases
TGTCCTCCATCGTCCTCGCCGAGCCCTCCGCACCGGTGGCGGGCGTTCTGCGCCGCTATCTCGAATCCGCCGGTCATGAA
GTGTCCTGGGTGAGCAGCGT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSGDVVAELKGRIDKSLEGLRTDLTRVRTGRASIAILEGVRVDYYGTPTPLSGVASVNAPEPRLITIKPWEKSVLKDIEK
ALREANLGINPMNDGEMIRLPFPPLTEERRKDIAKQVKTKGEEFKVTIRNLRRDANEVLKTQLKDKKITEDDHKRITEVV
QKQTDAGITQVDEIVKKKEKEVMEV

Sequences:

>Translated_185_residues
MSGDVVAELKGRIDKSLEGLRTDLTRVRTGRASIAILEGVRVDYYGTPTPLSGVASVNAPEPRLITIKPWEKSVLKDIEK
ALREANLGINPMNDGEMIRLPFPPLTEERRKDIAKQVKTKGEEFKVTIRNLRRDANEVLKTQLKDKKITEDDHKRITEVV
QKQTDAGITQVDEIVKKKEKEVMEV
>Mature_184_residues
SGDVVAELKGRIDKSLEGLRTDLTRVRTGRASIAILEGVRVDYYGTPTPLSGVASVNAPEPRLITIKPWEKSVLKDIEKA
LREANLGINPMNDGEMIRLPFPPLTEERRKDIAKQVKTKGEEFKVTIRNLRRDANEVLKTQLKDKKITEDDHKRITEVVQ
KQTDAGITQVDEIVKKKEKEVMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=44.8648648648649, Blast_Score=172, Evalue=1e-44,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_MYXXD (Q1D1I2)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_633491.1
- ProteinModelPortal:   Q1D1I2
- SMR:   Q1D1I2
- STRING:   Q1D1I2
- GeneID:   4103819
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_5341
- TIGR:   MXAN_5341
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q1D1I2
- BioCyc:   MXAN246197:MXAN_5341-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20913; Mature: 20782

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGDVVAELKGRIDKSLEGLRTDLTRVRTGRASIAILEGVRVDYYGTPTPLSGVASVNAP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCEEECCCCCCCCCCCCCCCCC
EPRLITIKPWEKSVLKDIEKALREANLGINPMNDGEMIRLPFPPLTEERRKDIAKQVKTK
CCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHC
GEEFKVTIRNLRRDANEVLKTQLKDKKITEDDHKRITEVVQKQTDAGITQVDEIVKKKEK
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EVMEV
HHHCC
>Mature Secondary Structure 
SGDVVAELKGRIDKSLEGLRTDLTRVRTGRASIAILEGVRVDYYGTPTPLSGVASVNAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCEEECCCCCCCCCCCCCCCCC
EPRLITIKPWEKSVLKDIEKALREANLGINPMNDGEMIRLPFPPLTEERRKDIAKQVKTK
CCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHC
GEEFKVTIRNLRRDANEVLKTQLKDKKITEDDHKRITEVVQKQTDAGITQVDEIVKKKEK
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EVMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA