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The map label for this gene is macB [H]

Identifier: 108761237

GI number: 108761237

Start: 125263

End: 126480

Strand: Direct

Name: macB [H]

Synonym: MXAN_0108

Alternate gene names: 108761237

Gene position: 125263-126480 (Clockwise)

Preceding gene: 108762317

Following gene: 108757767

Centisome position: 1.37

GC content: 67.73

Gene sequence:

>1218_bases
ATGGCAATCTGGGACACCCTGCGGCTGGCGTTCGGAACGTTCCGTTCCAACCTGCTGCGCTCCTTCCTGACGCTGCTGGG
CATCGTCATTGGCGCCACCACGGTGGTGTCGATGATGGGGCTCATCGAGGGCCTGCGCATCCAGGTGAACGAGAGCATGT
CCGAGCTGGGCTCCGACTGCTTCCAGGTGCAGCGGCTGCCCTTCGGCGGCAACCTGTCCCTGGCGGAGCTGGCGCGGCGG
CCCCGGCTGAACGAGGGCGACTTGGAGGCCATCCGGCTGCAGCCGTCGGTGCTGCTGGCGGCGGCGGAGGACTCCAAGGG
TGGACAGAAGGTGTCCACGCAGCAGCGCGAGTCGCGTCCCAATGTGGTCATCTGGGCCGGCACGCCGGAGTACTTCCAGA
CGAACTCGGTGGTGGTGGAGTTCGGGCGGCCCTTCACGGACGCGGAGTACCTGGATGGCCGCCGCGTGGCGGTGATTGGC
CAGGACCTGGCGGACACGTTGTTCCCGGGCGTGCAGCCCTTGGGGCAGAACATCCGCATCCTGGGGCGCAGCTTCCAGGT
GATTGGCACGCTCAAGCGCCGCGGCAGCTTCATGGGTGGAGGCAGCCAGGACAACCAGGTGATGATGCCGCTGTCCGTCT
ACAAGGCGCTGTTCGGGGTGCGCAACTACCGGGTGAGCGTCCAGGCCCAGTCGGCGGAGGTGCTCCAGCGCGCGCAGGAC
GAGGTGACGCTGCTGATGCGGCGGCGCCACAACCTGAAGCCGTTGGAGGAGGATGACTTCTTCGTGTTCTCCAACGAGAG
CGCCACGGAGATGTTCAACAACATCTCGAAGGTGATTTCTGCGGCCAGCTTCGGCGTGTGCATGCTGTCGCTGCTGGTGG
GCGGCATCGGCATCCTGAACATCATGCTGGTGGCGGTGACGGAGCGCACCCGGGAGATTGGCATCCGCAAGGCGCTGGGC
GCGAAGAGGCGCCGCATCCTCGCGCAGTTCGCCATCGAGGCGGTGGTGCTGTCGCTGGTGGGGGGCGCGTTGGGCGTGGG
CCTGGGCATGGGCCTGGCGCAACTGGCGAAGTGGATGGTGGGGCTTCCCGCGCAGGTGCCGGCCTGGGCGGTGATGCTGT
CGCTGGCCATGAGCAGCGGCGTGGGCCTGCTGTTCGGCATCTACCCGGCCGCGCGCGCCGCGAAGCTGGACCCCGTGGAG
GCCATGCGGACGGACTGA

Upstream 100 bases:

>100_bases
GTGGGGCTGCTGTTCGGCATCTGGCCGGCGGCGCGGGCGGCGAACCTGGACCCGGTGGAAGCGCTTCGCCACGAGTGACG
GACGGGAGACGGCGGCGATG

Downstream 100 bases:

>100_bases
CCCCACGCAGGTGCCGCAGGGTGGCTGGGAATGAAACGGGGCCTCCTCCGCGCGGTGCGGAAGAGGCCCCAGGTGTTTCA
GCACGTGTGTCCGGGGATTA

Product: putative ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MAIWDTLRLAFGTFRSNLLRSFLTLLGIVIGATTVVSMMGLIEGLRIQVNESMSELGSDCFQVQRLPFGGNLSLAELARR
PRLNEGDLEAIRLQPSVLLAAAEDSKGGQKVSTQQRESRPNVVIWAGTPEYFQTNSVVVEFGRPFTDAEYLDGRRVAVIG
QDLADTLFPGVQPLGQNIRILGRSFQVIGTLKRRGSFMGGGSQDNQVMMPLSVYKALFGVRNYRVSVQAQSAEVLQRAQD
EVTLLMRRRHNLKPLEEDDFFVFSNESATEMFNNISKVISAASFGVCMLSLLVGGIGILNIMLVAVTERTREIGIRKALG
AKRRRILAQFAIEAVVLSLVGGALGVGLGMGLAQLAKWMVGLPAQVPAWAVMLSLAMSSGVGLLFGIYPAARAAKLDPVE
AMRTD

Sequences:

>Translated_405_residues
MAIWDTLRLAFGTFRSNLLRSFLTLLGIVIGATTVVSMMGLIEGLRIQVNESMSELGSDCFQVQRLPFGGNLSLAELARR
PRLNEGDLEAIRLQPSVLLAAAEDSKGGQKVSTQQRESRPNVVIWAGTPEYFQTNSVVVEFGRPFTDAEYLDGRRVAVIG
QDLADTLFPGVQPLGQNIRILGRSFQVIGTLKRRGSFMGGGSQDNQVMMPLSVYKALFGVRNYRVSVQAQSAEVLQRAQD
EVTLLMRRRHNLKPLEEDDFFVFSNESATEMFNNISKVISAASFGVCMLSLLVGGIGILNIMLVAVTERTREIGIRKALG
AKRRRILAQFAIEAVVLSLVGGALGVGLGMGLAQLAKWMVGLPAQVPAWAVMLSLAMSSGVGLLFGIYPAARAAKLDPVE
AMRTD
>Mature_404_residues
AIWDTLRLAFGTFRSNLLRSFLTLLGIVIGATTVVSMMGLIEGLRIQVNESMSELGSDCFQVQRLPFGGNLSLAELARRP
RLNEGDLEAIRLQPSVLLAAAEDSKGGQKVSTQQRESRPNVVIWAGTPEYFQTNSVVVEFGRPFTDAEYLDGRRVAVIGQ
DLADTLFPGVQPLGQNIRILGRSFQVIGTLKRRGSFMGGGSQDNQVMMPLSVYKALFGVRNYRVSVQAQSAEVLQRAQDE
VTLLMRRRHNLKPLEEDDFFVFSNESATEMFNNISKVISAASFGVCMLSLLVGGIGILNIMLVAVTERTREIGIRKALGA
KRRRILAQFAIEAVVLSLVGGALGVGLGMGLAQLAKWMVGLPAQVPAWAVMLSLAMSSGVGLLFGIYPAARAAKLDPVEA
MRTD

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=407, Percent_Identity=32.4324324324324, Blast_Score=148, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44022; Mature: 43891

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIWDTLRLAFGTFRSNLLRSFLTLLGIVIGATTVVSMMGLIEGLRIQVNESMSELGSDC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHCHHH
FQVQRLPFGGNLSLAELARRPRLNEGDLEAIRLQPSVLLAAAEDSKGGQKVSTQQRESRP
HHHHCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCEEEEECCCCCCCCCCCHHHHHCCC
NVVIWAGTPEYFQTNSVVVEFGRPFTDAEYLDGRRVAVIGQDLADTLFPGVQPLGQNIRI
CEEEECCCCCHHCCCCEEEECCCCCCCHHHCCCCEEEEECCHHHHHHCCCCHHCCCCHHH
LGRSFQVIGTLKRRGSFMGGGSQDNQVMMPLSVYKALFGVRNYRVSVQAQSAEVLQRAQD
HHHHHHHHHHHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHCEEEEEEEHHHHHHHHHHH
EVTLLMRRRHNLKPLEEDDFFVFSNESATEMFNNISKVISAASFGVCMLSLLVGGIGILN
HHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMLVAVTERTREIGIRKALGAKRRRILAQFAIEAVVLSLVGGALGVGLGMGLAQLAKWMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLPAQVPAWAVMLSLAMSSGVGLLFGIYPAARAAKLDPVEAMRTD
CCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCCHHHHCCC
>Mature Secondary Structure 
AIWDTLRLAFGTFRSNLLRSFLTLLGIVIGATTVVSMMGLIEGLRIQVNESMSELGSDC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHCHHH
FQVQRLPFGGNLSLAELARRPRLNEGDLEAIRLQPSVLLAAAEDSKGGQKVSTQQRESRP
HHHHCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCEEEEECCCCCCCCCCCHHHHHCCC
NVVIWAGTPEYFQTNSVVVEFGRPFTDAEYLDGRRVAVIGQDLADTLFPGVQPLGQNIRI
CEEEECCCCCHHCCCCEEEECCCCCCCHHHCCCCEEEEECCHHHHHHCCCCHHCCCCHHH
LGRSFQVIGTLKRRGSFMGGGSQDNQVMMPLSVYKALFGVRNYRVSVQAQSAEVLQRAQD
HHHHHHHHHHHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHCEEEEEEEHHHHHHHHHHH
EVTLLMRRRHNLKPLEEDDFFVFSNESATEMFNNISKVISAASFGVCMLSLLVGGIGILN
HHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMLVAVTERTREIGIRKALGAKRRRILAQFAIEAVVLSLVGGALGVGLGMGLAQLAKWMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLPAQVPAWAVMLSLAMSSGVGLLFGIYPAARAAKLDPVEAMRTD
CCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA