Click here to switch to the map view.

The map label for this gene is macB [H]

Identifier: 108762317

GI number: 108762317

Start: 124014

End: 125240

Strand: Direct

Name: macB [H]

Synonym: MXAN_0107

Alternate gene names: 108762317

Gene position: 124014-125240 (Clockwise)

Preceding gene: 108763581

Following gene: 108761237

Centisome position: 1.36

GC content: 69.76

Gene sequence:

>1227_bases
GTGAGCATCCGGGTCGATGTGTGGGAGGGGGCGCGCATCGCGCTGTTCTCGCTCCGTTCCAACCGCCTGCGGACCGTGCT
GACGACGGTGGGCATTGGCGTGGGCGTGTGCACGCTGCTGGCCATTGTCGGCATCATCCAGGGCATCAACCGCTCCTTCG
AGGATCAGCTTTCGAGCATTGGCGCCAACACGCTCCAAATCTCGAAGTTCCCCTGGACGCTCAACGGCGACTGGTGGTCG
TACCGCAACCGCAAGGACCTGAGTGCGGACCTGGTGCCGCCCATCCTCAACGCGTCCGAGCACGTGCTGGCCGCGGCGCC
GCTCTTCTTCGAGCGCGTGGAGGGCCGCTTCCTGGACCGCAAAATCGGCTCGGTGCTGCTGGTGGGCACCACGCCGGACT
ACGCCACGGTGGGCTCGTTCGCCCTGGAGCGGGGCCGCTTCCTCACCCACGCGGACGTGGACAACCGGGCGCAGGTGGCC
GTCATCGGCGCGGAGCTCGTGCGCTCGCTCTTCCCCGGAGTGAACCCGGTGGGGCAGCGCATCCTCTTCGAGGGCAAGCC
CTTCCGCGTGGTGGGAACCCTGGAGGCCAAGGGCACCATCCTGGGAGAGAACCAGGACCTGGTGGTGGTGGTGCCCTCCC
GCACCTTCCTGGCGCACTTCGGCAAGAAGCGCTCGCCCAACATCGCGGTGGCCCTCACGTCGCCGGAGCATGCGCCAGCG
GTGGTGGACAAGCTCACCGCGGTGCTCCGCCGGGAGCGCAACACGCCGCCGGGGCTGCCGGACGACTTCGCCATCAACCG
GCCGGACCAGCTGGCCAGCATGTACGCGCAGCTCACCGGGGCGCTCTATGGCGCGGCCATGGGCGTGGGCCTCATCACGC
TGTTGGTGGGCGGCATCGGCATCATGAACATCATGCTGGTGTCGGTGCGCGAGCGGACGCGGGAGATTGGCGTCCGGCGG
GCGCTGGGGGCCCGCAAGCGCACCATCATCCTCCAGTTCCTGATGGAGGCCTCCTGCGTGTCCGCCCTGGGCGGCACCCT
GGGGACCGTGGTGGGCCTGGGGCTGGCGCGCATCGTGTCCTTGATTACGCCGCTGGCGGCGGCGGTGGAGCCGCTGACGG
TGGTGGCGGGCGTGGGGTTCGCGGCGATGGTGGGGCTGCTGTTCGGCATCTGGCCGGCGGCGCGGGCGGCGAACCTGGAC
CCGGTGGAAGCGCTTCGCCACGAGTGA

Upstream 100 bases:

>100_bases
CAGCACACTGGATTTGCACCGAAGGAATGTCGCGTGCAATCACCCGTTCCGGGGCCCGTACCAACCAGCGCGACGTGCAA
CGCAGCGGAGAGAATCTGAC

Downstream 100 bases:

>100_bases
CGGACGGGAGACGGCGGCGATGATGGCAATCTGGGACACCCTGCGGCTGGCGTTCGGAACGTTCCGTTCCAACCTGCTGC
GCTCCTTCCTGACGCTGCTG

Product: putative ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSIRVDVWEGARIALFSLRSNRLRTVLTTVGIGVGVCTLLAIVGIIQGINRSFEDQLSSIGANTLQISKFPWTLNGDWWS
YRNRKDLSADLVPPILNASEHVLAAAPLFFERVEGRFLDRKIGSVLLVGTTPDYATVGSFALERGRFLTHADVDNRAQVA
VIGAELVRSLFPGVNPVGQRILFEGKPFRVVGTLEAKGTILGENQDLVVVVPSRTFLAHFGKKRSPNIAVALTSPEHAPA
VVDKLTAVLRRERNTPPGLPDDFAINRPDQLASMYAQLTGALYGAAMGVGLITLLVGGIGIMNIMLVSVRERTREIGVRR
ALGARKRTIILQFLMEASCVSALGGTLGTVVGLGLARIVSLITPLAAAVEPLTVVAGVGFAAMVGLLFGIWPAARAANLD
PVEALRHE

Sequences:

>Translated_408_residues
MSIRVDVWEGARIALFSLRSNRLRTVLTTVGIGVGVCTLLAIVGIIQGINRSFEDQLSSIGANTLQISKFPWTLNGDWWS
YRNRKDLSADLVPPILNASEHVLAAAPLFFERVEGRFLDRKIGSVLLVGTTPDYATVGSFALERGRFLTHADVDNRAQVA
VIGAELVRSLFPGVNPVGQRILFEGKPFRVVGTLEAKGTILGENQDLVVVVPSRTFLAHFGKKRSPNIAVALTSPEHAPA
VVDKLTAVLRRERNTPPGLPDDFAINRPDQLASMYAQLTGALYGAAMGVGLITLLVGGIGIMNIMLVSVRERTREIGVRR
ALGARKRTIILQFLMEASCVSALGGTLGTVVGLGLARIVSLITPLAAAVEPLTVVAGVGFAAMVGLLFGIWPAARAANLD
PVEALRHE
>Mature_407_residues
SIRVDVWEGARIALFSLRSNRLRTVLTTVGIGVGVCTLLAIVGIIQGINRSFEDQLSSIGANTLQISKFPWTLNGDWWSY
RNRKDLSADLVPPILNASEHVLAAAPLFFERVEGRFLDRKIGSVLLVGTTPDYATVGSFALERGRFLTHADVDNRAQVAV
IGAELVRSLFPGVNPVGQRILFEGKPFRVVGTLEAKGTILGENQDLVVVVPSRTFLAHFGKKRSPNIAVALTSPEHAPAV
VDKLTAVLRRERNTPPGLPDDFAINRPDQLASMYAQLTGALYGAAMGVGLITLLVGGIGIMNIMLVSVRERTREIGVRRA
LGARKRTIILQFLMEASCVSALGGTLGTVVGLGLARIVSLITPLAAAVEPLTVVAGVGFAAMVGLLFGIWPAARAANLDP
VEALRHE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=403, Percent_Identity=31.7617866004963, Blast_Score=148, Evalue=8e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43706; Mature: 43575

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRVDVWEGARIALFSLRSNRLRTVLTTVGIGVGVCTLLAIVGIIQGINRSFEDQLSSI
CCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
GANTLQISKFPWTLNGDWWSYRNRKDLSADLVPPILNASEHVLAAAPLFFERVEGRFLDR
CCCEEEEEECCEEECCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCHHHHH
KIGSVLLVGTTPDYATVGSFALERGRFLTHADVDNRAQVAVIGAELVRSLFPGVNPVGQR
CCCCEEEEECCCCCHHHHHHHHHCCCEEEECCCCCCCEEEEEHHHHHHHHCCCCCCCCHH
ILFEGKPFRVVGTLEAKGTILGENQDLVVVVPSRTFLAHFGKKRSPNIAVALTSPEHAPA
EEECCCCEEEEEEEECCCEEECCCCCEEEEECCHHHHHHCCCCCCCCEEEEEECCCCCHH
VVDKLTAVLRRERNTPPGLPDDFAINRPDQLASMYAQLTGALYGAAMGVGLITLLVGGIG
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMNIMLVSVRERTREIGVRRALGARKRTIILQFLMEASCVSALGGTLGTVVGLGLARIVS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LITPLAAAVEPLTVVAGVGFAAMVGLLFGIWPAARAANLDPVEALRHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCC
>Mature Secondary Structure 
SIRVDVWEGARIALFSLRSNRLRTVLTTVGIGVGVCTLLAIVGIIQGINRSFEDQLSSI
CEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
GANTLQISKFPWTLNGDWWSYRNRKDLSADLVPPILNASEHVLAAAPLFFERVEGRFLDR
CCCEEEEEECCEEECCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCHHHHH
KIGSVLLVGTTPDYATVGSFALERGRFLTHADVDNRAQVAVIGAELVRSLFPGVNPVGQR
CCCCEEEEECCCCCHHHHHHHHHCCCEEEECCCCCCCEEEEEHHHHHHHHCCCCCCCCHH
ILFEGKPFRVVGTLEAKGTILGENQDLVVVVPSRTFLAHFGKKRSPNIAVALTSPEHAPA
EEECCCCEEEEEEEECCCEEECCCCCEEEEECCHHHHHHCCCCCCCCEEEEEECCCCCHH
VVDKLTAVLRRERNTPPGLPDDFAINRPDQLASMYAQLTGALYGAAMGVGLITLLVGGIG
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMNIMLVSVRERTREIGVRRALGARKRTIILQFLMEASCVSALGGTLGTVVGLGLARIVS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LITPLAAAVEPLTVVAGVGFAAMVGLLFGIWPAARAANLDPVEALRHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA