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The map label for this gene is 108760459

Identifier: 108760459

GI number: 108760459

Start: 4424570

End: 4426726

Strand: Direct

Name: 108760459

Synonym: MXAN_3710

Alternate gene names: NA

Gene position: 4424570-4426726 (Clockwise)

Preceding gene: 108762138

Following gene: 108760620

Centisome position: 48.41

GC content: 72.74

Gene sequence:

>2157_bases
GTGCGTGTGGTGTGGTTTCGTCTTTTCCGCCGTCACACGGCGACGTCCGGCGCGAAAGAAGCGATGACTGCCACGTACCG
GCTGACGGGCAAGGTGGAAGGCGGGGAGCTGGCCGAGCTGTATCAAGGCCTCGAGCTTCCCGGCATCCCCGTGGTGGTGA
AGCTCTTCCACCCCAGGACGTCCGATCCGGCCTACGCCCATGACCTGGCGGAGACGACGCGGCTGCTCCAGCCCGTGCGG
CACCCGGGCATCCTCCACGTCGTGGACCTGGGCGTCATCCGCCAGCGCCTGGCCGTGGTCCGCGAGGACGTGGACGGCTT
CACCCTGGGCACCGCGCTCCAGCGCCTGCACTCCAAGGACGTGGTGCTGCCGCCCACCGTGGCGCTCCACATCATCATCC
AGCTCCTGGAGGCCCTGCATCAGGCGCACGAGGCGGGCGTGGTGCACGGCGCCATCACCCCGGGCAACGTGGTGCTGTCG
CATGACGGCCTGCCCGCGGTGTGCGACTTCGGCGCGCTGCGCGCCCTCATGGCCGTGCCCCAACTGCGCAAGTCGTTTGG
CCACCGGGGCCGCGGCACGTACCGCGCGCCGGAAGTCACGCGGGGCGAGCCGCACTCCGCGCAGTCGGACATCTACTCGC
TCGGCGCCATCGCCTACGAGCTGCTCACCCAGCGTGAGCCCGTGGTGCCCGGCAGCGGCGGGGTGTCCACGCGGCGCAGT
GAGGCGTTGCCGCCGCCCAGCCGCGTGGACCGGCGCATCAATTCACGGCTGGACCCGCTCATCCTCCGCGCACTGGAGCC
CACGCCCCAGCGCCGCTTCCGCTCCTGTGGCGAGTTCGCCACGTCGCTTCGCAATCAGCTCGCGGCCAGCGGCGGCATGC
CCTCGGCGGACGACGTTCGCCGCTTCGTGCGGGAGCTGTTCCCCAACGAGATGAGCCTCGTCAGCTCGGGGCCTCCGCCG
TTCAAGGAGCCCTTCACGCTGGAGCCCATCTCCGGCGCGGAGATGGACGACCTGCGCGCGGAGGAGCTCGAGAAGTCCGT
GGTTCAGCGAGCCCCATACAGCCGCGCGCTGACCGAGGACGAGGCCAACGCGGAGACGCAGCAGGCCTCCGAGCCCGCGT
TCGAGGAGTACCGCCCGGAGCTGTACGAGCGGGACGTGGCGGACGCGGCCACGCGGGTGCGGGCACCCTCGCGCGCGTCC
GCCTCCGACTCCACCTCCGCGCCGGGGGAGGACACCGGGCCCGCTCCCGCCGGACCGCTGGAGCAGGGGTGGGAAGCGCC
GCCGGGCGCCGCTCCGCCGAAGCCTCGCCGCCAGCCGTCGTCGGTGGGGGGAGGGAGCGGCCACACCCGCATCGGGCGAA
ATCCGCGCCTCAAGGTCGTGGAGGACTTCTCCGCGCCCGAGCCGGCCGCGGATGACGAGGGCTCGATCTCCGTCTCCGCG
CCAGGTCGCCGCGGCGCTCGGATCCGCCGCGCCCCCATGGAGGCCAAGGGGCCCAAGACGATTCCGGACGTGTTGCCCGC
GGTGCAGCCGGCCTCGGCGCGAGCGCGTGACGACATCGCGATGCCGCCGTCCGATCCGGCGTTGCCTTCGACGTCCGACG
TGCACCGGCGCCTGGTGAGCGCGGAGCAGCGGTTGTCCGTGGCCCAGCACCGGTATGGACGCCGGTTGGGCATCGCGGCG
GCCATCGCCGGGGTGGGGTTGGTCACCTTCCTGGTGGCTGCATGGCAGCTCGGGGGGGATTCCGCACCCGCGCCGGAGGA
GGCCCCGCGGGAGGCGAAGGCCGAGGCCGCCCCCGTGGGCCCACCGCCCGCCATGCCCATCGCGCCGCCGGTGCCGGTGC
CAGTGCGTCCGCCGCCGCCCGCTCCAGAAGCCGCGTCGCGAGGGGGCGAGGAGGACGCGGCCCCCGAGCCGAAGCCTCCC
CCGAAGTCTCAGCGCGCGTATCTCACCATCACCACCAATGTGCCGGCGACCGTCTACGTCGACGGCGAGCGGCTGAGCCG
CCGTACGCCCCTCAACCGATACCCCGTCAAGGTGGGCACCCGGCGCATCAAGCTGGTGTCCGTCGCCACCGGTGAGCCCA
AGGAGCTGGACCTGCGCATCACGCGGGGGCAGCACCTCAAGGTCCTGGTGGACTCGTTCACGTCTCCGAGGCGGTGA

Upstream 100 bases:

>100_bases
CGCGAAGAACCGCCCAGCGTGCGGCCGAGCGCCCGGGCCGGGCCCGGCCCCGCTGCCCGGGGTGCACGCTGGAGCTGCCG
CGTGGCCGCCGCGGTGAGTC

Downstream 100 bases:

>100_bases
CCATGGACCCGACCCGCATCTTCGTCGTCGAGGATCAACCCCAGCTCCTCAAGAACCTGGTGAAGGTGCTGGCCACCTTC
CCCGAACTGGAGGTGGTAGG

Product: serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 718; Mature: 718

Protein sequence:

>718_residues
MRVVWFRLFRRHTATSGAKEAMTATYRLTGKVEGGELAELYQGLELPGIPVVVKLFHPRTSDPAYAHDLAETTRLLQPVR
HPGILHVVDLGVIRQRLAVVREDVDGFTLGTALQRLHSKDVVLPPTVALHIIIQLLEALHQAHEAGVVHGAITPGNVVLS
HDGLPAVCDFGALRALMAVPQLRKSFGHRGRGTYRAPEVTRGEPHSAQSDIYSLGAIAYELLTQREPVVPGSGGVSTRRS
EALPPPSRVDRRINSRLDPLILRALEPTPQRRFRSCGEFATSLRNQLAASGGMPSADDVRRFVRELFPNEMSLVSSGPPP
FKEPFTLEPISGAEMDDLRAEELEKSVVQRAPYSRALTEDEANAETQQASEPAFEEYRPELYERDVADAATRVRAPSRAS
ASDSTSAPGEDTGPAPAGPLEQGWEAPPGAAPPKPRRQPSSVGGGSGHTRIGRNPRLKVVEDFSAPEPAADDEGSISVSA
PGRRGARIRRAPMEAKGPKTIPDVLPAVQPASARARDDIAMPPSDPALPSTSDVHRRLVSAEQRLSVAQHRYGRRLGIAA
AIAGVGLVTFLVAAWQLGGDSAPAPEEAPREAKAEAAPVGPPPAMPIAPPVPVPVRPPPPAPEAASRGGEEDAAPEPKPP
PKSQRAYLTITTNVPATVYVDGERLSRRTPLNRYPVKVGTRRIKLVSVATGEPKELDLRITRGQHLKVLVDSFTSPRR

Sequences:

>Translated_718_residues
MRVVWFRLFRRHTATSGAKEAMTATYRLTGKVEGGELAELYQGLELPGIPVVVKLFHPRTSDPAYAHDLAETTRLLQPVR
HPGILHVVDLGVIRQRLAVVREDVDGFTLGTALQRLHSKDVVLPPTVALHIIIQLLEALHQAHEAGVVHGAITPGNVVLS
HDGLPAVCDFGALRALMAVPQLRKSFGHRGRGTYRAPEVTRGEPHSAQSDIYSLGAIAYELLTQREPVVPGSGGVSTRRS
EALPPPSRVDRRINSRLDPLILRALEPTPQRRFRSCGEFATSLRNQLAASGGMPSADDVRRFVRELFPNEMSLVSSGPPP
FKEPFTLEPISGAEMDDLRAEELEKSVVQRAPYSRALTEDEANAETQQASEPAFEEYRPELYERDVADAATRVRAPSRAS
ASDSTSAPGEDTGPAPAGPLEQGWEAPPGAAPPKPRRQPSSVGGGSGHTRIGRNPRLKVVEDFSAPEPAADDEGSISVSA
PGRRGARIRRAPMEAKGPKTIPDVLPAVQPASARARDDIAMPPSDPALPSTSDVHRRLVSAEQRLSVAQHRYGRRLGIAA
AIAGVGLVTFLVAAWQLGGDSAPAPEEAPREAKAEAAPVGPPPAMPIAPPVPVPVRPPPPAPEAASRGGEEDAAPEPKPP
PKSQRAYLTITTNVPATVYVDGERLSRRTPLNRYPVKVGTRRIKLVSVATGEPKELDLRITRGQHLKVLVDSFTSPRR
>Mature_718_residues
MRVVWFRLFRRHTATSGAKEAMTATYRLTGKVEGGELAELYQGLELPGIPVVVKLFHPRTSDPAYAHDLAETTRLLQPVR
HPGILHVVDLGVIRQRLAVVREDVDGFTLGTALQRLHSKDVVLPPTVALHIIIQLLEALHQAHEAGVVHGAITPGNVVLS
HDGLPAVCDFGALRALMAVPQLRKSFGHRGRGTYRAPEVTRGEPHSAQSDIYSLGAIAYELLTQREPVVPGSGGVSTRRS
EALPPPSRVDRRINSRLDPLILRALEPTPQRRFRSCGEFATSLRNQLAASGGMPSADDVRRFVRELFPNEMSLVSSGPPP
FKEPFTLEPISGAEMDDLRAEELEKSVVQRAPYSRALTEDEANAETQQASEPAFEEYRPELYERDVADAATRVRAPSRAS
ASDSTSAPGEDTGPAPAGPLEQGWEAPPGAAPPKPRRQPSSVGGGSGHTRIGRNPRLKVVEDFSAPEPAADDEGSISVSA
PGRRGARIRRAPMEAKGPKTIPDVLPAVQPASARARDDIAMPPSDPALPSTSDVHRRLVSAEQRLSVAQHRYGRRLGIAA
AIAGVGLVTFLVAAWQLGGDSAPAPEEAPREAKAEAAPVGPPPAMPIAPPVPVPVRPPPPAPEAASRGGEEDAAPEPKPP
PKSQRAYLTITTNVPATVYVDGERLSRRTPLNRYPVKVGTRRIKLVSVATGEPKELDLRITRGQHLKVLVDSFTSPRR

Specific function: Unknown

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI19424132, Length=255, Percent_Identity=23.921568627451, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI83367069, Length=205, Percent_Identity=27.8048780487805, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI4507281, Length=205, Percent_Identity=27.8048780487805, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI261244929, Length=271, Percent_Identity=22.8782287822878, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI222418622, Length=271, Percent_Identity=22.8782287822878, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI57222269, Length=189, Percent_Identity=27.5132275132275, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI217330634, Length=197, Percent_Identity=26.3959390862944, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI261244921, Length=271, Percent_Identity=22.8782287822878, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI261244925, Length=271, Percent_Identity=22.8782287822878, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI261244927, Length=271, Percent_Identity=22.8782287822878, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI261244923, Length=271, Percent_Identity=22.8782287822878, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI19923407, Length=271, Percent_Identity=22.8782287822878, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI5031689, Length=231, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI148833506, Length=158, Percent_Identity=31.6455696202532, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI115529463, Length=176, Percent_Identity=32.3863636363636, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI120659787, Length=176, Percent_Identity=32.3863636363636, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI150456432, Length=252, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI120659785, Length=177, Percent_Identity=32.2033898305085, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI19923468, Length=177, Percent_Identity=32.2033898305085, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI120659782, Length=177, Percent_Identity=32.2033898305085, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI55953117, Length=298, Percent_Identity=25.8389261744966, Blast_Score=67, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI193208793, Length=195, Percent_Identity=31.2820512820513, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193208795, Length=195, Percent_Identity=31.2820512820513, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17541726, Length=180, Percent_Identity=32.2222222222222, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI86562808, Length=182, Percent_Identity=25.8241758241758, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17511015, Length=180, Percent_Identity=27.2222222222222, Blast_Score=73, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319751, Length=188, Percent_Identity=30.3191489361702, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320095, Length=215, Percent_Identity=27.906976744186, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319917, Length=217, Percent_Identity=24.8847926267281, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320715, Length=207, Percent_Identity=27.0531400966184, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI221379848, Length=230, Percent_Identity=28.695652173913, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45551927, Length=230, Percent_Identity=28.695652173913, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45551925, Length=230, Percent_Identity=28.695652173913, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45551923, Length=230, Percent_Identity=28.695652173913, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550768, Length=230, Percent_Identity=28.695652173913, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076714, Length=189, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR005543
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271 [H]

Pfam domain/function: PF03793 PASTA; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 77243; Mature: 77243

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVWFRLFRRHTATSGAKEAMTATYRLTGKVEGGELAELYQGLELPGIPVVVKLFHPRT
CCHHHHHHHHHHHCCCCHHHHHEEEEEEEEECCCCHHHHHHCCCCCCCCCEEEEEECCCC
SDPAYAHDLAETTRLLQPVRHPGILHVVDLGVIRQRLAVVREDVDGFTLGTALQRLHSKD
CCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
VVLPPTVALHIIIQLLEALHQAHEAGVVHGAITPGNVVLSHDGLPAVCDFGALRALMAVP
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHH
QLRKSFGHRGRGTYRAPEVTRGEPHSAQSDIYSLGAIAYELLTQREPVVPGSGGVSTRRS
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
EALPPPSRVDRRINSRLDPLILRALEPTPQRRFRSCGEFATSLRNQLAASGGMPSADDVR
CCCCCHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
RFVRELFPNEMSLVSSGPPPFKEPFTLEPISGAEMDDLRAEELEKSVVQRAPYSRALTED
HHHHHHCCCHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCC
EANAETQQASEPAFEEYRPELYERDVADAATRVRAPSRASASDSTSAPGEDTGPAPAGPL
CCCCHHHHCCCCCHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCH
EQGWEAPPGAAPPKPRRQPSSVGGGSGHTRIGRNPRLKVVEDFSAPEPAADDEGSISVSA
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEECC
PGRRGARIRRAPMEAKGPKTIPDVLPAVQPASARARDDIAMPPSDPALPSTSDVHRRLVS
CCCCCCHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AEQRLSVAQHRYGRRLGIAAAIAGVGLVTFLVAAWQLGGDSAPAPEEAPREAKAEAAPVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCC
PPPAMPIAPPVPVPVRPPPPAPEAASRGGEEDAAPEPKPPPKSQRAYLTITTNVPATVYV
CCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEE
DGERLSRRTPLNRYPVKVGTRRIKLVSVATGEPKELDLRITRGQHLKVLVDSFTSPRR
CHHHHHHCCCCCCCCEEECCEEEEEEEECCCCCCEEEEEEECCCEEEHHHHCCCCCCC
>Mature Secondary Structure
MRVVWFRLFRRHTATSGAKEAMTATYRLTGKVEGGELAELYQGLELPGIPVVVKLFHPRT
CCHHHHHHHHHHHCCCCHHHHHEEEEEEEEECCCCHHHHHHCCCCCCCCCEEEEEECCCC
SDPAYAHDLAETTRLLQPVRHPGILHVVDLGVIRQRLAVVREDVDGFTLGTALQRLHSKD
CCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
VVLPPTVALHIIIQLLEALHQAHEAGVVHGAITPGNVVLSHDGLPAVCDFGALRALMAVP
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHH
QLRKSFGHRGRGTYRAPEVTRGEPHSAQSDIYSLGAIAYELLTQREPVVPGSGGVSTRRS
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
EALPPPSRVDRRINSRLDPLILRALEPTPQRRFRSCGEFATSLRNQLAASGGMPSADDVR
CCCCCHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
RFVRELFPNEMSLVSSGPPPFKEPFTLEPISGAEMDDLRAEELEKSVVQRAPYSRALTED
HHHHHHCCCHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCC
EANAETQQASEPAFEEYRPELYERDVADAATRVRAPSRASASDSTSAPGEDTGPAPAGPL
CCCCHHHHCCCCCHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCH
EQGWEAPPGAAPPKPRRQPSSVGGGSGHTRIGRNPRLKVVEDFSAPEPAADDEGSISVSA
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEECC
PGRRGARIRRAPMEAKGPKTIPDVLPAVQPASARARDDIAMPPSDPALPSTSDVHRRLVS
CCCCCCHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AEQRLSVAQHRYGRRLGIAAAIAGVGLVTFLVAAWQLGGDSAPAPEEAPREAKAEAAPVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCC
PPPAMPIAPPVPVPVRPPPPAPEAASRGGEEDAAPEPKPPPKSQRAYLTITTNVPATVYV
CCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEE
DGERLSRRTPLNRYPVKVGTRRIKLVSVATGEPKELDLRITRGQHLKVLVDSFTSPRR
CHHHHHHCCCCCCCCEEECCEEEEEEEECCCCCCEEEEEEECCCEEEHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]