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The map label for this gene is iscU [H]

Identifier: 108760385

GI number: 108760385

Start: 6253610

End: 6254011

Strand: Direct

Name: iscU [H]

Synonym: MXAN_5002

Alternate gene names: 108760385

Gene position: 6253610-6254011 (Clockwise)

Preceding gene: 108764054

Following gene: 108760194

Centisome position: 68.42

GC content: 65.42

Gene sequence:

>402_bases
ATGGCTTACAGCGACAAGGTCATCGAGCACTACGAGAACCCCCGGAACGTCGGGACGCTCGACAAGGAAGACCCGAACGT
GGGCACCGGCCTGGTGGGCGCGCCCGCCTGCGGCGACGTGATGCGCCTGCAGCTCAAGATTTCCGAGGACGGGCTCATCG
AGGACGCCCGCTTCAAGACGTTCGGCTGCGGGTCGGCCATTGCCTCGTCGTCGCTCGTCACCGAATGGGTGAAGGGCAAG
ACGGTGGACCAGGCGATGACCATCTCCAACAAGGACGTGGCCCGCGAGCTGTCGCTGCCGCCGGTGAAGATTCACTGCTC
CGTGCTGGCCGAGGACGCCATCAAGGCGGCCATCGAGGACTTCAAGAAGAAGCGCGCCGCGCGTCAGGCCAAGGCGTCCT
GA

Upstream 100 bases:

>100_bases
CTAGCGCCTTCTCAGGTAGACAGGGGGGCGCGAGCCCCCTCGCCCGGAGGGTGTTGCCCGCCGGAACCTTTGGTGAGAAG
CATCCGTTGAAGGAGCAGGC

Downstream 100 bases:

>100_bases
CGTTCGGGAAAGGGAGAGGCGAACCATGAGCGAACAGGCGACCCAGGAGACGACGCAGCGCCAGGCGCCTGCCACCGCGC
CCGTGGCCAAGCCCCCCAAG

Product: scaffold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MAYSDKVIEHYENPRNVGTLDKEDPNVGTGLVGAPACGDVMRLQLKISEDGLIEDARFKTFGCGSAIASSSLVTEWVKGK
TVDQAMTISNKDVARELSLPPVKIHCSVLAEDAIKAAIEDFKKKRAARQAKAS

Sequences:

>Translated_133_residues
MAYSDKVIEHYENPRNVGTLDKEDPNVGTGLVGAPACGDVMRLQLKISEDGLIEDARFKTFGCGSAIASSSLVTEWVKGK
TVDQAMTISNKDVARELSLPPVKIHCSVLAEDAIKAAIEDFKKKRAARQAKAS
>Mature_132_residues
AYSDKVIEHYENPRNVGTLDKEDPNVGTGLVGAPACGDVMRLQLKISEDGLIEDARFKTFGCGSAIASSSLVTEWVKGKT
VDQAMTISNKDVARELSLPPVKIHCSVLAEDAIKAAIEDFKKKRAARQAKAS

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=130, Percent_Identity=70.7692307692308, Blast_Score=202, Evalue=5e-53,
Organism=Homo sapiens, GI24307953, Length=129, Percent_Identity=70.5426356589147, Blast_Score=200, Evalue=3e-52,
Organism=Escherichia coli, GI1788878, Length=128, Percent_Identity=74.21875, Blast_Score=214, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17543474, Length=126, Percent_Identity=65.8730158730159, Blast_Score=194, Evalue=9e-51,
Organism=Saccharomyces cerevisiae, GI6325122, Length=124, Percent_Identity=71.7741935483871, Blast_Score=192, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6324800, Length=124, Percent_Identity=65.3225806451613, Blast_Score=181, Evalue=3e-47,
Organism=Drosophila melanogaster, GI21355597, Length=128, Percent_Identity=69.53125, Blast_Score=198, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011339
- InterPro:   IPR002871 [H]

Pfam domain/function: PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 14335; Mature: 14203

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSDKVIEHYENPRNVGTLDKEDPNVGTGLVGAPACGDVMRLQLKISEDGLIEDARFKT
CCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCC
FGCGSAIASSSLVTEWVKGKTVDQAMTISNKDVARELSLPPVKIHCSVLAEDAIKAAIED
CCCCHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHH
FKKKRAARQAKAS
HHHHHHHHHHCCC
>Mature Secondary Structure 
AYSDKVIEHYENPRNVGTLDKEDPNVGTGLVGAPACGDVMRLQLKISEDGLIEDARFKT
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCC
FGCGSAIASSSLVTEWVKGKTVDQAMTISNKDVARELSLPPVKIHCSVLAEDAIKAAIED
CCCCHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHH
FKKKRAARQAKAS
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]