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The map label for this gene is nuoE [H]

Identifier: 108760187

GI number: 108760187

Start: 1267093

End: 1267581

Strand: Reverse

Name: nuoE [H]

Synonym: MXAN_1086

Alternate gene names: 108760187

Gene position: 1267581-1267093 (Counterclockwise)

Preceding gene: 108760197

Following gene: 108760787

Centisome position: 13.87

GC content: 61.55

Gene sequence:

>489_bases
ATGGCGGAGCCCCTGTTCACCTCTGAAGAGCAGAAGAAGTTCGACGCGGGAATCGCGGAGATCATCTCCCACTACCCCCC
GGATCGGAAAAGCGCGGGCATGCTCCCAGCGCTGCGTCTGCTCCAGGAAATCAAGGGATGGCTGCCCCCGGAAGGGTTGC
GGCTGGTGGCGAAGCATCTGGAGGTCACTCCCGAGCGGGCCATGGAAGTGGCCAGCTTCTACGTGATGTACCACCTCAAG
AAGCCGGGCAAGTACGTCATCGACGTCTGCACGAACCTGTCCTGCTCGCTGTGGGGCGCGGAGAAGATGCTCGCCTACCT
GGAGGAGAAGCTGGGCCTCAAGGCAGGTGAAGCCAATGAGAAGTTCACCTTGCGAGAGACCGAGTGCCTGGCCTCGTGCG
GTACTGCGCCCTGCCTGCAGATCAACGAGGATCACCACGAAAGCCTGACCCAGGCGAAGCTGGATGCCATCCTCGCCAAG
TTGAGCTGA

Upstream 100 bases:

>100_bases
GGGCTTGAAATCGCTCGGCAATTTGCTGATGGCAACCCAGTGTAGCTTCGAGGGTTTATGTTGACAACGTAGCCATTGGG
GCAATACGTACCGGCCCGCC

Downstream 100 bases:

>100_bases
ACCCCCACCCTTCTTAGGCTTAGGACGTCATCGACATGGCCTCTACGGCAAAGACGATCGAACCGATCATCTCGGCGGCC
TGGGGTAAGCCTCAGTCCTG

Product: NADH dehydrogenase I subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MAEPLFTSEEQKKFDAGIAEIISHYPPDRKSAGMLPALRLLQEIKGWLPPEGLRLVAKHLEVTPERAMEVASFYVMYHLK
KPGKYVIDVCTNLSCSLWGAEKMLAYLEEKLGLKAGEANEKFTLRETECLASCGTAPCLQINEDHHESLTQAKLDAILAK
LS

Sequences:

>Translated_162_residues
MAEPLFTSEEQKKFDAGIAEIISHYPPDRKSAGMLPALRLLQEIKGWLPPEGLRLVAKHLEVTPERAMEVASFYVMYHLK
KPGKYVIDVCTNLSCSLWGAEKMLAYLEEKLGLKAGEANEKFTLRETECLASCGTAPCLQINEDHHESLTQAKLDAILAK
LS
>Mature_161_residues
AEPLFTSEEQKKFDAGIAEIISHYPPDRKSAGMLPALRLLQEIKGWLPPEGLRLVAKHLEVTPERAMEVASFYVMYHLKK
PGKYVIDVCTNLSCSLWGAEKMLAYLEEKLGLKAGEANEKFTLRETECLASCGTAPCLQINEDHHESLTQAKLDAILAKL
S

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=158, Percent_Identity=42.4050632911392, Blast_Score=129, Evalue=1e-30,
Organism=Escherichia coli, GI1788621, Length=141, Percent_Identity=31.2056737588652, Blast_Score=79, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17561328, Length=158, Percent_Identity=43.6708860759494, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI18859877, Length=158, Percent_Identity=39.873417721519, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21355353, Length=158, Percent_Identity=33.5443037974684, Blast_Score=105, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18059; Mature: 17928

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPLFTSEEQKKFDAGIAEIISHYPPDRKSAGMLPALRLLQEIKGWLPPEGLRLVAKHL
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
EVTPERAMEVASFYVMYHLKKPGKYVIDVCTNLSCSLWGAEKMLAYLEEKLGLKAGEANE
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
KFTLRETECLASCGTAPCLQINEDHHESLTQAKLDAILAKLS
CEEHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEPLFTSEEQKKFDAGIAEIISHYPPDRKSAGMLPALRLLQEIKGWLPPEGLRLVAKHL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
EVTPERAMEVASFYVMYHLKKPGKYVIDVCTNLSCSLWGAEKMLAYLEEKLGLKAGEANE
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
KFTLRETECLASCGTAPCLQINEDHHESLTQAKLDAILAKLS
CEEHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]