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The map label for this gene is ag45 [H]

Identifier: 108759911

GI number: 108759911

Start: 4609134

End: 4610393

Strand: Direct

Name: ag45 [H]

Synonym: MXAN_3834

Alternate gene names: 108759911

Gene position: 4609134-4610393 (Clockwise)

Preceding gene: 108763416

Following gene: 108762290

Centisome position: 50.43

GC content: 68.97

Gene sequence:

>1260_bases
GTGTGCCGCGCCGTGGCCCTCGCCATCTTCCTGTTCACCTACGTCTTCATCGCCGGTGCGCGCCTTCCGTACCTGAAGCT
GGACCGCCCCGGGGGCGCGCTGCTGGGGGCCGTGCTGATGGTCGTCTTCGGCGTCGTCACTCCGGCCGAGGTCTTCAACC
ACAGCGCCGACGCGAACCGTCACGCCATCGACGCGGACACCATCGTCCTCCTGCTGGGGATGATGCTGCTGGCGGCGTAC
ATGTCCCAGGCGTCCTTCTTCCGCACCGCGGGCGCGTGGGCCGTGCGCAGGGCGCACACGCCCCGGCGGTTGCTGCTCGC
CGTGACGTTCATTTCGGCCGCGCTGTCCGCGTTCCTGGTGAATGACACCGTGTGTTTGATGCTCACGCCCCTGGTGCTGG
CCACCGTGGAGGACGCGCGCCTGCCGCCGGCTCCGTACCTGCTCGCGGTGTGCATGGGCAGCAACAGCGGCTCGGTGGCG
ACCTTCACCGGCAACCCGCAGAACATGCTCATCCAGGGCGCCTCCGGGCTGTCCTACGCCAGCTTCGCGGCGTACATGGC
CCTGCCTGCCCTGCTCTCCACAGCGGTGGTCGCCGCCGGACTCCTGTATCTGTTCCGGCATGACCTGCCCGTGAAGCAAT
TCGAGCCCAACCCTCCACCTCCGCCCGTGGACCGGGGCCTGTTGGTGCTCACCTTGACGGTGCTATCCGGGGTTGTCGTG
GCCTTCTTCGCCGGGCTGCCCATGAGCTGGAGCGCCCTGGCCGGCGCGGCCCTGGTGATGGCCCTGGCGCGCCGCGAGCC
ACGCGAGGCGCTGGAGCGCGTGGACTGGGTGCTGCTGCTCTTCTTCGCGAGCCTGTTCGTGGTCGTCTATGGCGTGAACA
AGCACGGCTACGCGGAGGACATCCGCGTCCTGTTCGAGCCCCTCATGGCGGGTCCGCCCCTTAGGGAGACGCTGGGCTTC
GCGGGGCTGACGCTGGTGGCGTCCAACCTGTTCAGCAACGTGCCCTTCGTCATGCTGGCGCGGACGTGGGTGCCCACGCT
GCACGACGTGGAGCTGGGCTGGCACGTGCTCGCGCTGGGCTCCACGCTGGCGGGCAACCTCACGCTGGTGGGAAGCGTGG
CCAACCTCATCGTGTTCGAGGCCGCGCGCGGGAAGGTCAACATGAGCTTCCTCCGCTTCCTCCGCGTGGGCCTCCCGGTG
ACGCTCGTCAGCTTCGTCGTGGGGCTGAGCGTGCTCCTGGTGGAGCACGCGCTGTTCTGA

Upstream 100 bases:

>100_bases
ACTGTACAGACGTATACCGAGGCAAACAACGCGGGAGCGCACCTCATTGGTTTGAGCTCCAGCCAATACGCGCAGAGGCG
GACGTGCGGGCACTCCACTA

Downstream 100 bases:

>100_bases
ATCAGGCCGTGTGACTCAGGGGTCGGGGTCCGGCAGCTCGCCGGGCGCCAGCTCGTCTTCCGGAGGCTTCGTCGCCTCGG
GTGCCGGAGCCGGGGCGCCC

Product: arsenical pump membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MCRAVALAIFLFTYVFIAGARLPYLKLDRPGGALLGAVLMVVFGVVTPAEVFNHSADANRHAIDADTIVLLLGMMLLAAY
MSQASFFRTAGAWAVRRAHTPRRLLLAVTFISAALSAFLVNDTVCLMLTPLVLATVEDARLPPAPYLLAVCMGSNSGSVA
TFTGNPQNMLIQGASGLSYASFAAYMALPALLSTAVVAAGLLYLFRHDLPVKQFEPNPPPPPVDRGLLVLTLTVLSGVVV
AFFAGLPMSWSALAGAALVMALARREPREALERVDWVLLLFFASLFVVVYGVNKHGYAEDIRVLFEPLMAGPPLRETLGF
AGLTLVASNLFSNVPFVMLARTWVPTLHDVELGWHVLALGSTLAGNLTLVGSVANLIVFEAARGKVNMSFLRFLRVGLPV
TLVSFVVGLSVLLVEHALF

Sequences:

>Translated_419_residues
MCRAVALAIFLFTYVFIAGARLPYLKLDRPGGALLGAVLMVVFGVVTPAEVFNHSADANRHAIDADTIVLLLGMMLLAAY
MSQASFFRTAGAWAVRRAHTPRRLLLAVTFISAALSAFLVNDTVCLMLTPLVLATVEDARLPPAPYLLAVCMGSNSGSVA
TFTGNPQNMLIQGASGLSYASFAAYMALPALLSTAVVAAGLLYLFRHDLPVKQFEPNPPPPPVDRGLLVLTLTVLSGVVV
AFFAGLPMSWSALAGAALVMALARREPREALERVDWVLLLFFASLFVVVYGVNKHGYAEDIRVLFEPLMAGPPLRETLGF
AGLTLVASNLFSNVPFVMLARTWVPTLHDVELGWHVLALGSTLAGNLTLVGSVANLIVFEAARGKVNMSFLRFLRVGLPV
TLVSFVVGLSVLLVEHALF
>Mature_419_residues
MCRAVALAIFLFTYVFIAGARLPYLKLDRPGGALLGAVLMVVFGVVTPAEVFNHSADANRHAIDADTIVLLLGMMLLAAY
MSQASFFRTAGAWAVRRAHTPRRLLLAVTFISAALSAFLVNDTVCLMLTPLVLATVEDARLPPAPYLLAVCMGSNSGSVA
TFTGNPQNMLIQGASGLSYASFAAYMALPALLSTAVVAAGLLYLFRHDLPVKQFEPNPPPPPVDRGLLVLTLTVLSGVVV
AFFAGLPMSWSALAGAALVMALARREPREALERVDWVLLLFFASLFVVVYGVNKHGYAEDIRVLFEPLMAGPPLRETLGF
AGLTLVASNLFSNVPFVMLARTWVPTLHDVELGWHVLALGSTLAGNLTLVGSVANLIVFEAARGKVNMSFLRFLRVGLPV
TLVSFVVGLSVLLVEHALF

Specific function: Unknown

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Homo sapiens, GI157266326, Length=218, Percent_Identity=34.8623853211009, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1787039, Length=360, Percent_Identity=30.2777777777778, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87082277, Length=405, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581759, Length=221, Percent_Identity=32.579185520362, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920704, Length=221, Percent_Identity=32.579185520362, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28574683, Length=221, Percent_Identity=32.579185520362, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28574681, Length=221, Percent_Identity=32.579185520362, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28574685, Length=221, Percent_Identity=32.579185520362, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28574678, Length=221, Percent_Identity=32.579185520362, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 44835; Mature: 44835

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRAVALAIFLFTYVFIAGARLPYLKLDRPGGALLGAVLMVVFGVVTPAEVFNHSADANR
CHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
HAIDADTIVLLLGMMLLAAYMSQASFFRTAGAWAVRRAHTPRRLLLAVTFISAALSAFLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
NDTVCLMLTPLVLATVEDARLPPAPYLLAVCMGSNSGSVATFTGNPQNMLIQGASGLSYA
CCHHHHHHHHHHHHHHHHCCCCCCHHEEEEEECCCCCCEEEEECCCCCEEEECCCCCCHH
SFAAYMALPALLSTAVVAAGLLYLFRHDLPVKQFEPNPPPPPVDRGLLVLTLTVLSGVVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AFFAGLPMSWSALAGAALVMALARREPREALERVDWVLLLFFASLFVVVYGVNKHGYAED
HHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
IRVLFEPLMAGPPLRETLGFAGLTLVASNLFSNVPFVMLARTWVPTLHDVELGWHVLALG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEHHHCEEHEECC
STLAGNLTLVGSVANLIVFEAARGKVNMSFLRFLRVGLPVTLVSFVVGLSVLLVEHALF
CHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MCRAVALAIFLFTYVFIAGARLPYLKLDRPGGALLGAVLMVVFGVVTPAEVFNHSADANR
CHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
HAIDADTIVLLLGMMLLAAYMSQASFFRTAGAWAVRRAHTPRRLLLAVTFISAALSAFLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
NDTVCLMLTPLVLATVEDARLPPAPYLLAVCMGSNSGSVATFTGNPQNMLIQGASGLSYA
CCHHHHHHHHHHHHHHHHCCCCCCHHEEEEEECCCCCCEEEEECCCCCEEEECCCCCCHH
SFAAYMALPALLSTAVVAAGLLYLFRHDLPVKQFEPNPPPPPVDRGLLVLTLTVLSGVVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AFFAGLPMSWSALAGAALVMALARREPREALERVDWVLLLFFASLFVVVYGVNKHGYAED
HHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
IRVLFEPLMAGPPLRETLGFAGLTLVASNLFSNVPFVMLARTWVPTLHDVELGWHVLALG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEHHHCEEHEECC
STLAGNLTLVGSVANLIVFEAARGKVNMSFLRFLRVGLPVTLVSFVVGLSVLLVEHALF
CHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]