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The map label for this gene is holB [H]

Identifier: 108759549

GI number: 108759549

Start: 3268360

End: 3269394

Strand: Direct

Name: holB [H]

Synonym: MXAN_2800

Alternate gene names: 108759549

Gene position: 3268360-3269394 (Clockwise)

Preceding gene: 108759834

Following gene: 108761070

Centisome position: 35.76

GC content: 72.46

Gene sequence:

>1035_bases
ATGACGCTCGCAACGGTACTGGGACAGCCTCGCGCGGTGGACGCCCTCCAGGCGGCCCTGCGCAGCGGCGCGGTCCACCA
CGCGTACCTCTTCGCCGGGCCAGAAGGGGTGGGCAAGGAGCTGGCGGCCGTCGGGCTGGCCCAGGCCCTCACGTGCCCCG
AGCAGCCAGACGTGGGCTGCGGCGCCTGCGCGAGCTGCCAGCGGGTGGAGAGGGGCCTCCACCCGGACGTCACCTGGGTG
ATGCCTGACGATGAACGGGTGTCCCGGGGGCTGGCGGGTCGGTCCGACTTCACTGGGACGCCCAGCCGGGAGCTACGCGT
GGAGCAGGTGCGCCAGCTCCAGGAGCGCATCGCCCTTCGCGGCCTGGAGTCGCGCCGCAAGGTGGCGCTCATCGTCTCCG
CCCAGACCATGAACGTGCAGGCGCAGAACGCGTTCCTCAAGACGCTGGAGGAGCCGCCTTCGGACACCACGATCATCCTG
GTGGCCAGCGCGATTGACCGCCTGCTGCCCACCATTCGCAGCCGGTGCGGAAAGGTGCACTTCGGCCCACTGCCGGTGGA
CATGGTGGCCCAGCGCGTGGCGGAGGCGCGCAAGCTGGACGCGGAGACGGCCATGCTCGCGGCCGTCATGGCGGGCGGCA
GCCTGGGCCGGGCCATGGCGCTGGACGTGGACGCGCTGTCGCGGCGCAAGGACACCCTCACCGCCTTCGAGGCCCTGCGC
GGCGAGGACGCCGTCGGCCTGCTGCGCTTCGCGGAGGCCCATGGCGGCTCGCGCGAGGAGGCGGAGAGCACCCTGGAGCT
GCTGGCGCTGTGGACGCGCGACGTGGCGCTGGTGAAGTCAGGCCTGGAGTCGGGGCTGGCCAACCGCGACATGGTGGACC
TGGCCCGGCAGGTGGCGGCCCGCACGTCCGACATCCTCCTGCACCGCCGGCATTCGCTGCTGGATGCGGCGCGGGCGGCC
ATTGCCCGGAACGGTGCGCCCCGGCTCCAACTGGAGCGGATGCTCATCGACCTGTTCACGGAGGCGTCGCGATGA

Upstream 100 bases:

>100_bases
CTGAAGGAAGGGCAGCAAGGCGGGGGGAATGTCTCCCGCCATCTCCATGGGGGTCAAGGCGGCCGTTGACGCGTGCCGCG
TGAGCGGGGATACACGCGCC

Downstream 100 bases:

>100_bases
GCGCCAGTGAGATGGATGACGTGCTGGCGAGCGTGAAGGGGGGCAAGGTCGCCCCGGTGTACCTCTTGGTGGGCGAGGAA
TTCCTGGTCCGCAAGGGCGC

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTLATVLGQPRAVDALQAALRSGAVHHAYLFAGPEGVGKELAAVGLAQALTCPEQPDVGCGACASCQRVERGLHPDVTWV
MPDDERVSRGLAGRSDFTGTPSRELRVEQVRQLQERIALRGLESRRKVALIVSAQTMNVQAQNAFLKTLEEPPSDTTIIL
VASAIDRLLPTIRSRCGKVHFGPLPVDMVAQRVAEARKLDAETAMLAAVMAGGSLGRAMALDVDALSRRKDTLTAFEALR
GEDAVGLLRFAEAHGGSREEAESTLELLALWTRDVALVKSGLESGLANRDMVDLARQVAARTSDILLHRRHSLLDAARAA
IARNGAPRLQLERMLIDLFTEASR

Sequences:

>Translated_344_residues
MTLATVLGQPRAVDALQAALRSGAVHHAYLFAGPEGVGKELAAVGLAQALTCPEQPDVGCGACASCQRVERGLHPDVTWV
MPDDERVSRGLAGRSDFTGTPSRELRVEQVRQLQERIALRGLESRRKVALIVSAQTMNVQAQNAFLKTLEEPPSDTTIIL
VASAIDRLLPTIRSRCGKVHFGPLPVDMVAQRVAEARKLDAETAMLAAVMAGGSLGRAMALDVDALSRRKDTLTAFEALR
GEDAVGLLRFAEAHGGSREEAESTLELLALWTRDVALVKSGLESGLANRDMVDLARQVAARTSDILLHRRHSLLDAARAA
IARNGAPRLQLERMLIDLFTEASR
>Mature_343_residues
TLATVLGQPRAVDALQAALRSGAVHHAYLFAGPEGVGKELAAVGLAQALTCPEQPDVGCGACASCQRVERGLHPDVTWVM
PDDERVSRGLAGRSDFTGTPSRELRVEQVRQLQERIALRGLESRRKVALIVSAQTMNVQAQNAFLKTLEEPPSDTTIILV
ASAIDRLLPTIRSRCGKVHFGPLPVDMVAQRVAEARKLDAETAMLAAVMAGGSLGRAMALDVDALSRRKDTLTAFEALRG
EDAVGLLRFAEAHGGSREEAESTLELLALWTRDVALVKSGLESGLANRDMVDLARQVAARTSDILLHRRHSLLDAARAAI
ARNGAPRLQLERMLIDLFTEASR

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=193, Percent_Identity=33.160621761658, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787341, Length=211, Percent_Identity=29.3838862559242, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 37042; Mature: 36911

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLATVLGQPRAVDALQAALRSGAVHHAYLFAGPEGVGKELAAVGLAQALTCPEQPDVGC
CCHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC
GACASCQRVERGLHPDVTWVMPDDERVSRGLAGRSDFTGTPSRELRVEQVRQLQERIALR
CHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GLESRRKVALIVSAQTMNVQAQNAFLKTLEEPPSDTTIILVASAIDRLLPTIRSRCGKVH
CCCCCCEEEEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCC
FGPLPVDMVAQRVAEARKLDAETAMLAAVMAGGSLGRAMALDVDALSRRKDTLTAFEALR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEECHHHHHHHHHHHHHHHHHC
GEDAVGLLRFAEAHGGSREEAESTLELLALWTRDVALVKSGLESGLANRDMVDLARQVAA
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
RTSDILLHRRHSLLDAARAAIARNGAPRLQLERMLIDLFTEASR
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLATVLGQPRAVDALQAALRSGAVHHAYLFAGPEGVGKELAAVGLAQALTCPEQPDVGC
CHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC
GACASCQRVERGLHPDVTWVMPDDERVSRGLAGRSDFTGTPSRELRVEQVRQLQERIALR
CHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GLESRRKVALIVSAQTMNVQAQNAFLKTLEEPPSDTTIILVASAIDRLLPTIRSRCGKVH
CCCCCCEEEEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCC
FGPLPVDMVAQRVAEARKLDAETAMLAAVMAGGSLGRAMALDVDALSRRKDTLTAFEALR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEECHHHHHHHHHHHHHHHHHC
GEDAVGLLRFAEAHGGSREEAESTLELLALWTRDVALVKSGLESGLANRDMVDLARQVAA
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
RTSDILLHRRHSLLDAARAAIARNGAPRLQLERMLIDLFTEASR
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]