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The map label for this gene is prpE [H]

Identifier: 108759347

GI number: 108759347

Start: 1771438

End: 1772145

Strand: Reverse

Name: prpE [H]

Synonym: MXAN_1509

Alternate gene names: 108759347

Gene position: 1772145-1771438 (Counterclockwise)

Preceding gene: 108763629

Following gene: 108757107

Centisome position: 19.39

GC content: 68.22

Gene sequence:

>708_bases
ATGTCCCGCCGCACCATCGTCATCGGAGACCTTCACGGCTGCTACGACGAAGCCGTGGAGCTGCTCGGCAAGGTGGGCGC
GACCTCCAGCGACCGGATCATCTTCGCGGGTGACCTGGTGGACCGGGGCCCGAAGCGCCGCGAGTGCGTGGAGTTGGCCA
TGCGGCACGAGGCCATCCTCGGCAACCACGAGGAGAAGCACCTCCAGCAGCGCCACCGGGCGGACGAGCGGTTGCATCCC
GACCACCTCGAGACTCGCCGGGTGCTCCAACCCGGGCACTACGACTGGATGGCCCGGCTGCCACGCTACCTGCGGCTGCC
GGAGCACAACGCCATCGTGGTGCACGCCGGCATGCTGCCGGACATCCCTGTCGAGAAACAGGACCCGTACCACCTGCTCC
ATGCCCAGTGCATCCGGCCTCCGGCGTCCAAGAGCTACTGGCCGTCCAAGGCACCTCATGGCTGGACCTTCTGGACGCAC
CACTGGAAGGGCCCGGAGCGGGTCATCTTCGGTCACACCGTCTTCGACGCGCCGCTCGTCACCGAGCACGCGGTGGGTAT
CGACACCGGGTGCGTCTATGGACGGTCGCTGACGGCGGTGGTGCTCCCCACCTGGGAGCTCGTCTCGGTGCCGGCCCGGA
GTACGTACCGGGGCGGCAAGGACGTGGCCCGGATTCCGGTCCACGGCGACGTGTCCGTCTTCTCGTAA

Upstream 100 bases:

>100_bases
CATGGGCGTATGCCGACGGGTGGTCCGTCACTGATCCTGGAATCAGCCAACTGGCTTCTTCACTCGGGCGCTCATTTTTC
GCTTCTTGAGGATTCGCGTC

Downstream 100 bases:

>100_bases
TCAATTTCGCGCCCGGCCGACGGGGTCCAACACGCCATACAGCTGTCGCGGGTTCGAATCCCGCCGGAGCCGTTCGTGGC
TCCGTAGCTCAGCGGTAGAG

Product: serine/threonine protein phosphatase family protein

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSRRTIVIGDLHGCYDEAVELLGKVGATSSDRIIFAGDLVDRGPKRRECVELAMRHEAILGNHEEKHLQQRHRADERLHP
DHLETRRVLQPGHYDWMARLPRYLRLPEHNAIVVHAGMLPDIPVEKQDPYHLLHAQCIRPPASKSYWPSKAPHGWTFWTH
HWKGPERVIFGHTVFDAPLVTEHAVGIDTGCVYGRSLTAVVLPTWELVSVPARSTYRGGKDVARIPVHGDVSVFS

Sequences:

>Translated_235_residues
MSRRTIVIGDLHGCYDEAVELLGKVGATSSDRIIFAGDLVDRGPKRRECVELAMRHEAILGNHEEKHLQQRHRADERLHP
DHLETRRVLQPGHYDWMARLPRYLRLPEHNAIVVHAGMLPDIPVEKQDPYHLLHAQCIRPPASKSYWPSKAPHGWTFWTH
HWKGPERVIFGHTVFDAPLVTEHAVGIDTGCVYGRSLTAVVLPTWELVSVPARSTYRGGKDVARIPVHGDVSVFS
>Mature_234_residues
SRRTIVIGDLHGCYDEAVELLGKVGATSSDRIIFAGDLVDRGPKRRECVELAMRHEAILGNHEEKHLQQRHRADERLHPD
HLETRRVLQPGHYDWMARLPRYLRLPEHNAIVVHAGMLPDIPVEKQDPYHLLHAQCIRPPASKSYWPSKAPHGWTFWTHH
WKGPERVIFGHTVFDAPLVTEHAVGIDTGCVYGRSLTAVVLPTWELVSVPARSTYRGGKDVARIPVHGDVSVFS

Specific function: Asymmetrically hydrolyzes Ap4p to yield AMP and ATP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prpE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.17 [H]

Molecular weight: Translated: 26658; Mature: 26527

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRTIVIGDLHGCYDEAVELLGKVGATSSDRIIFAGDLVDRGPKRRECVELAMRHEAIL
CCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEECCHHCCCCCHHHHHHHHHHHHHHH
GNHEEKHLQQRHRADERLHPDHLETRRVLQPGHYDWMARLPRYLRLPEHNAIVVHAGMLP
CCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCC
DIPVEKQDPYHLLHAQCIRPPASKSYWPSKAPHGWTFWTHHWKGPERVIFGHTVFDAPLV
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEECEEECCCCH
TEHAVGIDTGCVYGRSLTAVVLPTWELVSVPARSTYRGGKDVARIPVHGDVSVFS
HHHHCCCCCCCCCCCCEEEEEECCHHHEECCCCCCCCCCCCEEEECCCCCCEECC
>Mature Secondary Structure 
SRRTIVIGDLHGCYDEAVELLGKVGATSSDRIIFAGDLVDRGPKRRECVELAMRHEAIL
CCCEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEECCHHCCCCCHHHHHHHHHHHHHHH
GNHEEKHLQQRHRADERLHPDHLETRRVLQPGHYDWMARLPRYLRLPEHNAIVVHAGMLP
CCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCC
DIPVEKQDPYHLLHAQCIRPPASKSYWPSKAPHGWTFWTHHWKGPERVIFGHTVFDAPLV
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEECEEECCCCH
TEHAVGIDTGCVYGRSLTAVVLPTWELVSVPARSTYRGGKDVARIPVHGDVSVFS
HHHHCCCCCCCCCCCCEEEEEECCHHHEECCCCCCCCCCCCEEEECCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]