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The map label for this gene is nuoC2 [H]

Identifier: 108759239

GI number: 108759239

Start: 3180713

End: 3181183

Strand: Reverse

Name: nuoC2 [H]

Synonym: MXAN_2730

Alternate gene names: 108759239

Gene position: 3181183-3180713 (Counterclockwise)

Preceding gene: 108758077

Following gene: 108758426

Centisome position: 34.81

GC content: 67.52

Gene sequence:

>471_bases
GTGGATCGGACCGGAGGCGCCTGGGCCGTCATCCATGCAGACTCGCTCCCGAAGGTCGCCGCGTTCCTGAAGAACGACCC
GGAGCTGGAGTTCAAGCTGTTCGGCTCCATCGACGCCGTGGATCGGCTGCACCTGGCGGAGAACGACCCTCGCTTCGAGG
TCGTCTACTTCCTCTACTCCCTCAAGCGGCACGAGCACGTGCGGCTCAAGGTGCGGGTGAGCGAAGCCAACCCGGTGGTG
CCCACCCTGGTGCCGCTCTTCCGCGGCGCCAACTGGTGGGAGCGGCTGACCTTCGACTTCTACGGCATCCGCTTCGACGG
GCACCCGGACCTGCGCCGCATCCTCCTCTACGACGAGTTCGAGGGGCACCCCCTGCGCAAGGACTACGCGCTGCGTGACC
GGCAGCCGCTCATCCCCGAGCGCCCCATCAAGGACATCTTCCGCGGTCCCGGCACCAGCGGGCTCTCCTGA

Upstream 100 bases:

>100_bases
AGCCGCGGATTCTTCTCCCTTAGTCATTGGGGCACCCTTGAGCACTTTCGCGTTGGACAGGGTCTCCGCCCAGCTCCCAG
AGGCGGTGGCGGATCGCTAC

Downstream 100 bases:

>100_bases
GCGAGGACATCCATGGCTGACACCCTCAAGCCCGAAGCGCCGAACCCCGACACCGACGCGTACGCCCACGAGTCGGAGCT
GGACGCCCACCTCCAGACCA

Product: NADH dehydrogenase I subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C 2; NDH-1 subunit C 2 [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MDRTGGAWAVIHADSLPKVAAFLKNDPELEFKLFGSIDAVDRLHLAENDPRFEVVYFLYSLKRHEHVRLKVRVSEANPVV
PTLVPLFRGANWWERLTFDFYGIRFDGHPDLRRILLYDEFEGHPLRKDYALRDRQPLIPERPIKDIFRGPGTSGLS

Sequences:

>Translated_156_residues
MDRTGGAWAVIHADSLPKVAAFLKNDPELEFKLFGSIDAVDRLHLAENDPRFEVVYFLYSLKRHEHVRLKVRVSEANPVV
PTLVPLFRGANWWERLTFDFYGIRFDGHPDLRRILLYDEFEGHPLRKDYALRDRQPLIPERPIKDIFRGPGTSGLS
>Mature_156_residues
MDRTGGAWAVIHADSLPKVAAFLKNDPELEFKLFGSIDAVDRLHLAENDPRFEVVYFLYSLKRHEHVRLKVRVSEANPVV
PTLVPLFRGANWWERLTFDFYGIRFDGHPDLRRILLYDEFEGHPLRKDYALRDRQPLIPERPIKDIFRGPGTSGLS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=122, Percent_Identity=40.9836065573771, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI145693162, Length=134, Percent_Identity=44.0298507462687, Blast_Score=94, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71990788, Length=122, Percent_Identity=40.1639344262295, Blast_Score=93, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI32563621, Length=122, Percent_Identity=40.1639344262295, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24656494, Length=122, Percent_Identity=38.5245901639344, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18140; Mature: 18140

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRTGGAWAVIHADSLPKVAAFLKNDPELEFKLFGSIDAVDRLHLAENDPRFEVVYFLYS
CCCCCCEEEEEECCCCHHHHHHHCCCCCEEEEEECCCCCHHHEEECCCCCCEEEHHEEHH
LKRHEHVRLKVRVSEANPVVPTLVPLFRGANWWERLTFDFYGIRFDGHPDLRRILLYDEF
HCCCCEEEEEEEECCCCCCHHHHHHHHCCCCHHHHEEEEEEEEEECCCCCCEEEEEEECC
EGHPLRKDYALRDRQPLIPERPIKDIFRGPGTSGLS
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MDRTGGAWAVIHADSLPKVAAFLKNDPELEFKLFGSIDAVDRLHLAENDPRFEVVYFLYS
CCCCCCEEEEEECCCCHHHHHHHCCCCCEEEEEECCCCCHHHEEECCCCCCEEEHHEEHH
LKRHEHVRLKVRVSEANPVVPTLVPLFRGANWWERLTFDFYGIRFDGHPDLRRILLYDEF
HCCCCEEEEEEEECCCCCCHHHHHHHHCCCCHHHHEEEEEEEEEECCCCCCEEEEEEECC
EGHPLRKDYALRDRQPLIPERPIKDIFRGPGTSGLS
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]