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The map label for this gene is pgcA [H]

Identifier: 108759054

GI number: 108759054

Start: 7084937

End: 7086664

Strand: Reverse

Name: pgcA [H]

Synonym: MXAN_5717

Alternate gene names: 108759054

Gene position: 7086664-7084937 (Counterclockwise)

Preceding gene: 108761287

Following gene: 108757559

Centisome position: 77.54

GC content: 72.51

Gene sequence:

>1728_bases
ATGGACACCACCGGACTGAAGGAGCGGGCGGAGGCGTGGCGTCAGGCGGACCCGGATCCGTCCACCGCGGCGGAGCTGGC
GGCGTTGCTGGCGAAGGCGGACTGGGCCGAGCTGGAGGACCGCTTCTCGCAGGACCTGGAGTTCGGCACCGCGGGCCTGC
GCGGCGTGCTGGGCGCCGGTCCCAACCGGATGAACCGCGCCGTCATCCGCCGCACCACCGCGGGCCTTGCGCGCTACCTC
AAGGAGCAGGTGCCGGACGTCGCCACCCGGGGCGTGGTGGTGGGCCGTGACGCGCGCAACCTGAGCGCGGAGCTGGCCGA
GGACACCGCCGCGGTGCTCGCCGCCGAGGGCATCCCCGCCCATGTCTTCCCGGAGCCGGTGCCCACGCCGCTGGTGGCCT
TTGCCGCGCTGCACCTCAACGCCGCCGCGGCCGTCATGGTGACGGCCAGCCACAACCCGCCCGAGTACAACGGCTACAAG
GTCTATTGGGGCAACGGCGCGCAAATCATCCCGCCGCATGACACGGGCATCGCCTCCGCCATCGCCCGGGTGGAGCCCGC
CAACCGCGTGCCGCTGCTGACGCCGGCCGATGCGCGCGCCAAGGGCCTGTGGCGGGATTTGCCTGCGGCCATCGGCGATG
CCTACGTGCGCGCCATCCTGGGGCTGCGCGTGGTGGGCAAGGGCTCCGAGTCGCTGTCCATCGTCTACACCGCCATGCAC
GGCGTGGGCGGCGACTGGGCCGTGCGCGCCCTGCGCGAGGCGGGCTTCCCGCGCGTCACCCCCGTGGCCGAGCAGCAGCA
GCCGGATGGCCGCTTCCCCACCGTGCGCTTCCCCAACCCGGAGGAGCCGGGCGCCATGGACCTGGCCACCGCCACCGCCG
AGCGCGTGAAGGCGGACGTGGTGCTGGCCAATGACCCGGACGCGGACCGGCTGGCCGTCATGGCGCGCGACGCGGACGGG
TCGCTGCGGCTGCTGACGGGCAACGAGGTGGGCGTGCTGCTGGGCCACTACGTCCTCACCCAGGGGGCGAAGCAGGGCAA
GCCCCACGTCGTCACCACCATCGTCTCCTCGGCGCAGTTGGGAGACATCGCGCGCTCGCTGGGCGCCGCGTGTGACGAGG
TGCTCACCGGCTTCAAGTGGATCGCCAACCGCGCGCTGGAGCGCGAGCAGGCCGAGGGCACCCGCTTCGTCTTCGGTTAC
GAGGAGGCGCTGGGCTACACCGTGGGCACGGTGACGCGCGACAAGGACGGCGTGGGCTCGGCGCTCGTCATGGCGGACCT
GGCGGCGTGGTGTCAGGCGCGCGGCACCACGGTGCTGGGCTACCTGGAGGAGATTCAGCGCGCGCATGGCCTGTACGTGG
GCGCGCAGCGCAACTTCACGTTCCCCGGTGCGGCGGGCGCGCAGGTCATCCGCGGCATCATGGACGCGTTCCGTGCCTCG
CCTCCGAAGGACATTGGCGGCGACGCCGTCCGTGCCGTGAGCGACTACAAGAAGGGCGAGCGGGGCCTGCCTCCGTCCAA
CGTCGTCGCGCTCGAGTTGGAGAGCGGCGGCCGCGTCACGCTGCGCCCCTCCGGCACCGAGCCGAAAATCAAATACTACT
TCGAGCTGAAGGAGACGCTCGCCGACGGTGAGCCCCTGGCTCAGGCCCGTGCGCGCGCCGAGTCCCGGCTGGCCCGCTTC
ATCGATGCTTTCCTCGGCCTCGCGCGTGAGCGCGGGCAGCCGGCATGA

Upstream 100 bases:

>100_bases
CGCGCCACCCGCAGCAAGCTGACCGACTACACCTGAACAACCGGCGTGCGAGCCCCGTGCCTCGCGCGCCCTCAACGGCT
ACACGAGGCTTCGAGGGCTC

Downstream 100 bases:

>100_bases
GTCTAGAGACGCAGCACCGCACCCACCGCCCGCCGTCCTCGGCGGCCCTCGCAGAAAGGTACCGTGTGAAGCGACTGCTC
CCCGGAGTCCTCCTCGCTTG

Product: putative phosphoglucomutase/phosphomannomutase

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MDTTGLKERAEAWRQADPDPSTAAELAALLAKADWAELEDRFSQDLEFGTAGLRGVLGAGPNRMNRAVIRRTTAGLARYL
KEQVPDVATRGVVVGRDARNLSAELAEDTAAVLAAEGIPAHVFPEPVPTPLVAFAALHLNAAAAVMVTASHNPPEYNGYK
VYWGNGAQIIPPHDTGIASAIARVEPANRVPLLTPADARAKGLWRDLPAAIGDAYVRAILGLRVVGKGSESLSIVYTAMH
GVGGDWAVRALREAGFPRVTPVAEQQQPDGRFPTVRFPNPEEPGAMDLATATAERVKADVVLANDPDADRLAVMARDADG
SLRLLTGNEVGVLLGHYVLTQGAKQGKPHVVTTIVSSAQLGDIARSLGAACDEVLTGFKWIANRALEREQAEGTRFVFGY
EEALGYTVGTVTRDKDGVGSALVMADLAAWCQARGTTVLGYLEEIQRAHGLYVGAQRNFTFPGAAGAQVIRGIMDAFRAS
PPKDIGGDAVRAVSDYKKGERGLPPSNVVALELESGGRVTLRPSGTEPKIKYYFELKETLADGEPLAQARARAESRLARF
IDAFLGLARERGQPA

Sequences:

>Translated_575_residues
MDTTGLKERAEAWRQADPDPSTAAELAALLAKADWAELEDRFSQDLEFGTAGLRGVLGAGPNRMNRAVIRRTTAGLARYL
KEQVPDVATRGVVVGRDARNLSAELAEDTAAVLAAEGIPAHVFPEPVPTPLVAFAALHLNAAAAVMVTASHNPPEYNGYK
VYWGNGAQIIPPHDTGIASAIARVEPANRVPLLTPADARAKGLWRDLPAAIGDAYVRAILGLRVVGKGSESLSIVYTAMH
GVGGDWAVRALREAGFPRVTPVAEQQQPDGRFPTVRFPNPEEPGAMDLATATAERVKADVVLANDPDADRLAVMARDADG
SLRLLTGNEVGVLLGHYVLTQGAKQGKPHVVTTIVSSAQLGDIARSLGAACDEVLTGFKWIANRALEREQAEGTRFVFGY
EEALGYTVGTVTRDKDGVGSALVMADLAAWCQARGTTVLGYLEEIQRAHGLYVGAQRNFTFPGAAGAQVIRGIMDAFRAS
PPKDIGGDAVRAVSDYKKGERGLPPSNVVALELESGGRVTLRPSGTEPKIKYYFELKETLADGEPLAQARARAESRLARF
IDAFLGLARERGQPA
>Mature_575_residues
MDTTGLKERAEAWRQADPDPSTAAELAALLAKADWAELEDRFSQDLEFGTAGLRGVLGAGPNRMNRAVIRRTTAGLARYL
KEQVPDVATRGVVVGRDARNLSAELAEDTAAVLAAEGIPAHVFPEPVPTPLVAFAALHLNAAAAVMVTASHNPPEYNGYK
VYWGNGAQIIPPHDTGIASAIARVEPANRVPLLTPADARAKGLWRDLPAAIGDAYVRAILGLRVVGKGSESLSIVYTAMH
GVGGDWAVRALREAGFPRVTPVAEQQQPDGRFPTVRFPNPEEPGAMDLATATAERVKADVVLANDPDADRLAVMARDADG
SLRLLTGNEVGVLLGHYVLTQGAKQGKPHVVTTIVSSAQLGDIARSLGAACDEVLTGFKWIANRALEREQAEGTRFVFGY
EEALGYTVGTVTRDKDGVGSALVMADLAAWCQARGTTVLGYLEEIQRAHGLYVGAQRNFTFPGAAGAQVIRGIMDAFRAS
PPKDIGGDAVRAVSDYKKGERGLPPSNVVALELESGGRVTLRPSGTEPKIKYYFELKETLADGEPLAQARARAESRLARF
IDAFLGLARERGQPA

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=567, Percent_Identity=35.8024691358025, Blast_Score=332, Evalue=7e-91,
Organism=Homo sapiens, GI31377548, Length=587, Percent_Identity=35.7751277683135, Blast_Score=317, Evalue=2e-86,
Organism=Escherichia coli, GI1788361, Length=270, Percent_Identity=29.2592592592593, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789566, Length=495, Percent_Identity=25.6565656565657, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71993870, Length=555, Percent_Identity=36.3963963963964, Blast_Score=301, Evalue=7e-82,
Organism=Caenorhabditis elegans, GI71993878, Length=319, Percent_Identity=37.9310344827586, Blast_Score=195, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6323934, Length=590, Percent_Identity=36.4406779661017, Blast_Score=303, Evalue=5e-83,
Organism=Drosophila melanogaster, GI20129809, Length=592, Percent_Identity=36.6554054054054, Blast_Score=323, Evalue=3e-88,
Organism=Drosophila melanogaster, GI24651977, Length=460, Percent_Identity=40.4347826086956, Blast_Score=302, Evalue=5e-82,
Organism=Drosophila melanogaster, GI24653722, Length=558, Percent_Identity=32.258064516129, Blast_Score=258, Evalue=5e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 61157; Mature: 61157

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTTGLKERAEAWRQADPDPSTAAELAALLAKADWAELEDRFSQDLEFGTAGLRGVLGAG
CCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHCCC
PNRMNRAVIRRTTAGLARYLKEQVPDVATRGVVVGRDARNLSAELAEDTAAVLAAEGIPA
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEECCCHHHHHHHHHHHHHHHHCCCCCC
HVFPEPVPTPLVAFAALHLNAAAAVMVTASHNPPEYNGYKVYWGNGAQIIPPHDTGIASA
CCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCCCCEEEEECCCCEEECCCCCHHHHH
IARVEPANRVPLLTPADARAKGLWRDLPAAIGDAYVRAILGLRVVGKGSESLSIVYTAMH
HHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEHH
GVGGDWAVRALREAGFPRVTPVAEQQQPDGRFPTVRFPNPEEPGAMDLATATAERVKADV
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHEEEE
VLANDPDADRLAVMARDADGSLRLLTGNEVGVLLGHYVLTQGAKQGKPHVVTTIVSSAQL
EEECCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHH
GDIARSLGAACDEVLTGFKWIANRALEREQAEGTRFVFGYEEALGYTVGTVTRDKDGVGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCEEEEEEECCCCCCCH
ALVMADLAAWCQARGTTVLGYLEEIQRAHGLYVGAQRNFTFPGAAGAQVIRGIMDAFRAS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCC
PPKDIGGDAVRAVSDYKKGERGLPPSNVVALELESGGRVTLRPSGTEPKIKYYFELKETL
CCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCEEEEEEEHHHH
ADGEPLAQARARAESRLARFIDAFLGLARERGQPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDTTGLKERAEAWRQADPDPSTAAELAALLAKADWAELEDRFSQDLEFGTAGLRGVLGAG
CCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHCCC
PNRMNRAVIRRTTAGLARYLKEQVPDVATRGVVVGRDARNLSAELAEDTAAVLAAEGIPA
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEECCCHHHHHHHHHHHHHHHHCCCCCC
HVFPEPVPTPLVAFAALHLNAAAAVMVTASHNPPEYNGYKVYWGNGAQIIPPHDTGIASA
CCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCCCCEEEEECCCCEEECCCCCHHHHH
IARVEPANRVPLLTPADARAKGLWRDLPAAIGDAYVRAILGLRVVGKGSESLSIVYTAMH
HHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEHH
GVGGDWAVRALREAGFPRVTPVAEQQQPDGRFPTVRFPNPEEPGAMDLATATAERVKADV
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHEEEE
VLANDPDADRLAVMARDADGSLRLLTGNEVGVLLGHYVLTQGAKQGKPHVVTTIVSSAQL
EEECCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHH
GDIARSLGAACDEVLTGFKWIANRALEREQAEGTRFVFGYEEALGYTVGTVTRDKDGVGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCEEEEEEECCCCCCCH
ALVMADLAAWCQARGTTVLGYLEEIQRAHGLYVGAQRNFTFPGAAGAQVIRGIMDAFRAS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCC
PPKDIGGDAVRAVSDYKKGERGLPPSNVVALELESGGRVTLRPSGTEPKIKYYFELKETL
CCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCEEEEEEEHHHH
ADGEPLAQARARAESRLARFIDAFLGLARERGQPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]