Click here to switch to the map view.

The map label for this gene is dys1 [H]

Identifier: 108758175

GI number: 108758175

Start: 1985910

End: 1986932

Strand: Direct

Name: dys1 [H]

Synonym: MXAN_1678

Alternate gene names: 108758175

Gene position: 1985910-1986932 (Clockwise)

Preceding gene: 108763577

Following gene: 108763878

Centisome position: 21.73

GC content: 63.34

Gene sequence:

>1023_bases
ATGTCCTCGTCCGAACTTCCCGTTCTCAAGTTCGTCCTCACGAACTACAAGAATTTCAACGCGCGCGCGACGCGCGATGC
GCTCCTGTCCTACTGGGAGCATGTGTCGAACGGTGGCCGGATGTTCTGGAGCGTCGCGGGCGCGATGTCGTCGGCGCAGC
TCGGCATCACGCTCGCACCGGCCATCCGGGCGGGGCTGATTCACGGTCTGTCGGTGACGGGCGCCAACATCGAGGAGTCG
CTCTTCCGGCTCGTCGCGCATACGGGGTACAAGGACTTCCCGGAGTACCGCTACTTCACCAAGCAGGACGACACGCGAAT
CCTCGAGCAGCGGATGCGCCGGGTCACCGATACGAGCATCCCCGAGGACGAGGCGTTCCGCGCGGTGGAGAAGATTGCCG
TTCCGATGTGGAAGGGCGCGACCGAGAAGGGCGAGCGCCGCTTCTGGCACGAGTACTTCTACGCGTTCATCCAGGCGCTC
GACCCCTCCGTGTATGAGGGTGACCCGGAGGCCTGCTGGCTGCTCGAGGCGGCGCGGCTCCGTCTGCCCATCGTCGTCCC
TGGCTATGAGGACTCGACGTTCGGCAACATCTTCGCGTCCTACGTGAAGGCGGGCGACTTCAACGCGAGCATCGTCAAGT
CTGGCATTGAGTACATGGCCGACTTCTACGACCGCTACGAGGAGATGTCCGAGGGCCGGGGTGTCGGCTTCTTCCAGATT
GGCGGCGGTATCGCCGGTGACTTCCCCATCTGCGTCGTTCCTTCGATCAAGTACGACCTGCAGAAGCCGGTGAAGCCCTG
GGCCTACTTCTGCCAGATCAGCGACTCGACGACGTCCTACGGTTCGTACTCGGGCGCGACGCCCAATGAGAAGATCACCT
GGGACAAGCTGACCGAGACGACGCCGATGTTCGTCATCGAGTCGGATGCCACCATTGTCGCGCCGCTGATTCTCAGCGCC
CTGCTCGAGTGCAAGAGCAACCCGGAAGCGGCGAACGCGCTCATCGCGAAGCACCAGGGCTAG

Upstream 100 bases:

>100_bases
TGGCGGCCGCGACATCTCGTTGCGACCGTAGGGTGTCCTCGAGTGGCTCTGTCAGGCGTGTGCCTCTCGAGCATTCACCA
CGTTGTTGCTGGAGGCTCAC

Downstream 100 bases:

>100_bases
CCGTCGCAGCAGGCGGGGCGGCTCGCGCCGCTCCGCACGTGGGAATGGCGTGACGCTGCCACGACGCACGGGATGCCGTG
CGTCGCGGTCCCCCAGTCAG

Product: deoxyhypusine synthase family protein

Products: NA

Alternate protein names: DHS 1 [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSSSELPVLKFVLTNYKNFNARATRDALLSYWEHVSNGGRMFWSVAGAMSSAQLGITLAPAIRAGLIHGLSVTGANIEES
LFRLVAHTGYKDFPEYRYFTKQDDTRILEQRMRRVTDTSIPEDEAFRAVEKIAVPMWKGATEKGERRFWHEYFYAFIQAL
DPSVYEGDPEACWLLEAARLRLPIVVPGYEDSTFGNIFASYVKAGDFNASIVKSGIEYMADFYDRYEEMSEGRGVGFFQI
GGGIAGDFPICVVPSIKYDLQKPVKPWAYFCQISDSTTSYGSYSGATPNEKITWDKLTETTPMFVIESDATIVAPLILSA
LLECKSNPEAANALIAKHQG

Sequences:

>Translated_340_residues
MSSSELPVLKFVLTNYKNFNARATRDALLSYWEHVSNGGRMFWSVAGAMSSAQLGITLAPAIRAGLIHGLSVTGANIEES
LFRLVAHTGYKDFPEYRYFTKQDDTRILEQRMRRVTDTSIPEDEAFRAVEKIAVPMWKGATEKGERRFWHEYFYAFIQAL
DPSVYEGDPEACWLLEAARLRLPIVVPGYEDSTFGNIFASYVKAGDFNASIVKSGIEYMADFYDRYEEMSEGRGVGFFQI
GGGIAGDFPICVVPSIKYDLQKPVKPWAYFCQISDSTTSYGSYSGATPNEKITWDKLTETTPMFVIESDATIVAPLILSA
LLECKSNPEAANALIAKHQG
>Mature_339_residues
SSSELPVLKFVLTNYKNFNARATRDALLSYWEHVSNGGRMFWSVAGAMSSAQLGITLAPAIRAGLIHGLSVTGANIEESL
FRLVAHTGYKDFPEYRYFTKQDDTRILEQRMRRVTDTSIPEDEAFRAVEKIAVPMWKGATEKGERRFWHEYFYAFIQALD
PSVYEGDPEACWLLEAARLRLPIVVPGYEDSTFGNIFASYVKAGDFNASIVKSGIEYMADFYDRYEEMSEGRGVGFFQIG
GGIAGDFPICVVPSIKYDLQKPVKPWAYFCQISDSTTSYGSYSGATPNEKITWDKLTETTPMFVIESDATIVAPLILSAL
LECKSNPEAANALIAKHQG

Specific function: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine

COG id: COG1899

COG function: function code O; Deoxyhypusine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoxyhypusine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002773
- InterPro:   IPR022899 [H]

Pfam domain/function: PF01916 DS [H]

EC number: =2.5.1.46 [H]

Molecular weight: Translated: 37963; Mature: 37832

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSELPVLKFVLTNYKNFNARATRDALLSYWEHVSNGGRMFWSVAGAMSSAQLGITLAP
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCEEEHH
AIRAGLIHGLSVTGANIEESLFRLVAHTGYKDFPEYRYFTKQDDTRILEQRMRRVTDTSI
HHHHHHHHCCEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
PEDEAFRAVEKIAVPMWKGATEKGERRFWHEYFYAFIQALDPSVYEGDPEACWLLEAARL
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
RLPIVVPGYEDSTFGNIFASYVKAGDFNASIVKSGIEYMADFYDRYEEMSEGRGVGFFQI
CCCEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
GGGIAGDFPICVVPSIKYDLQKPVKPWAYFCQISDSTTSYGSYSGATPNEKITWDKLTET
CCCCCCCCCEEEECCCCHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEHHHHCCC
TPMFVIESDATIVAPLILSALLECKSNPEAANALIAKHQG
CCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
SSSELPVLKFVLTNYKNFNARATRDALLSYWEHVSNGGRMFWSVAGAMSSAQLGITLAP
CCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCEEEHH
AIRAGLIHGLSVTGANIEESLFRLVAHTGYKDFPEYRYFTKQDDTRILEQRMRRVTDTSI
HHHHHHHHCCEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
PEDEAFRAVEKIAVPMWKGATEKGERRFWHEYFYAFIQALDPSVYEGDPEACWLLEAARL
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
RLPIVVPGYEDSTFGNIFASYVKAGDFNASIVKSGIEYMADFYDRYEEMSEGRGVGFFQI
CCCEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
GGGIAGDFPICVVPSIKYDLQKPVKPWAYFCQISDSTTSYGSYSGATPNEKITWDKLTET
CCCCCCCCCEEEECCCCHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEHHHHCCC
TPMFVIESDATIVAPLILSALLECKSNPEAANALIAKHQG
CCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]