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The map label for this gene is tldD [H]

Identifier: 108757909

GI number: 108757909

Start: 2930682

End: 2932163

Strand: Reverse

Name: tldD [H]

Synonym: MXAN_2519

Alternate gene names: 108757909

Gene position: 2932163-2930682 (Counterclockwise)

Preceding gene: 108761947

Following gene: 108762948

Centisome position: 32.08

GC content: 70.31

Gene sequence:

>1482_bases
ATGCCCCGAGCGTCTGCGCCCTCGAAGCGCGCCCTCTCATTGAAGCTCGCCCCACCGGTGGCCCGGCGGCCCACGCCCGT
CGCCCTGCTGCCCCAGCCGCTGGTCGAGCGCCTGCTCGCCGTGGCCATGGAGCGGGGGGGCGACTTCGCGGAGGTGTACG
TCGAGCGCACGCTCACCACGGCGGTGCGGCTGGAAGAATCCCGCATCAAGAGCGCGCAGACGGGCCTGGTCCAGGGCGTG
GGTGTGCGCGTCATCTCCGGCGGCAAGGTGGGCTACGCCTTCTCCGACGACTGGGATGAGTCCGCGCTGCTGCGCGCGGC
CTCCACGGCGGTCATGATTGCCCAGGGCGGCGGCGCCGAGCGCAGCTTCCCCGTGCGCCGCGCCGCGGTCCCCAGCCACT
ACCACGTCAGCCCCCCGCTGATGGACGTGGAGGTGTCGCTGAAGACGGGACTGCTCATGCGCGCCGACAAGGCCGCCCGC
GCCTTCGACGCGCGGGTGAAGCAGGTCAACGGCGGCTACGTGGACCAGACCCGGCGCATCGCCGTGGCCAACACCCACGG
GCGCTACACCGAGGACACCCAGGACCTGTGCCGGATTTCGGTGATGGTGGTGGCCCAGGGCACGGGCGGCGAGCGGCGCA
CCGGCATGTACGGCGGCGGCGGACGCGTGCCCTTCAGCCACTGGGACACCTTCTCCCCGGAGGACGTGGCCCGGGAAGCG
GCGCGTCAGGCGGTGGCCACGCTGGGCGCGGTGGACTGCGTGGCCGGCCCGCAGACGGTGGTGCTGGCGCCGGGCTGGAG
CGGCATCCTCCTGCACGAGGCGGTGGGCCACGGCCTGGAGGCGGACTTCATCCGCAAGGGCACCTCGCTGTTCGCTGGGA
AGCTGGGTGAGAAGGTGGCGTCCGACCTGGTCACCATCATCGACGACGGCACCGTGTCCAGCGGGCGCGGCTCCATCAAC
ATCGACGATGAGGGCAACCCCGGCGAGCGCAAGGTCCTCATCGAGAACGGCGTCCTCAAGGGCTACCTCTACGACAGCCT
GAACGCACAGCTCATGGGCCAGCGCAGCACCGGCAGCGGGCGGCGCGAGTCCTTCAAGCACCTGCCCATGCCCCGCATGA
CAAATACCTTCCTGGCCCCGGGCGACCACGCCCCCGAGGACATCCTCAAGGAGGTGAAGCGCGGCCTGTACTGCGCCACC
TTCGGCGGTGGGCAGGTGGACATCACCAACGGCAACTTCGTCTTCGAGGTCAGCGAGGCCTATCAAATCGAGGACGGCAA
GCTGGGCCGTCCCGTGAAGAACGCGACGCTCATCGGCGTGGGGCCGGAGGCGCTGAAGAACGTGTCACGAGTGGGCTGCG
ACCCCATGCCGGACCCAGGCATGGGCATCTGCGGGAAGAATGGCCAGTCCATGCCCGTGGGCGTGGGGCTGCCCACCGTG
CGCATCGACAACATCACCGTTGGCGGAACCAAGGTCGCCTGA

Upstream 100 bases:

>100_bases
CAGGGAAAGAACGGGGGCCCTTGAGCGTTGCTCCTGGCGGCGCCCCCTCCTATGTAGGCTGTCACATACCCCATCGTCTT
CACTGCGGGAGTCCCGAAAT

Downstream 100 bases:

>100_bases
GAGAGAGCACCAACCATGGACTACCAGCAGCTCGCGAAGAGAATCGTCCAGCGCGCCAAGCGCAAGGGTGCTCGCCAGGC
GGAGGCCTTCCTGGAGGTGG

Product: TldD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MPRASAPSKRALSLKLAPPVARRPTPVALLPQPLVERLLAVAMERGGDFAEVYVERTLTTAVRLEESRIKSAQTGLVQGV
GVRVISGGKVGYAFSDDWDESALLRAASTAVMIAQGGGAERSFPVRRAAVPSHYHVSPPLMDVEVSLKTGLLMRADKAAR
AFDARVKQVNGGYVDQTRRIAVANTHGRYTEDTQDLCRISVMVVAQGTGGERRTGMYGGGGRVPFSHWDTFSPEDVAREA
ARQAVATLGAVDCVAGPQTVVLAPGWSGILLHEAVGHGLEADFIRKGTSLFAGKLGEKVASDLVTIIDDGTVSSGRGSIN
IDDEGNPGERKVLIENGVLKGYLYDSLNAQLMGQRSTGSGRRESFKHLPMPRMTNTFLAPGDHAPEDILKEVKRGLYCAT
FGGGQVDITNGNFVFEVSEAYQIEDGKLGRPVKNATLIGVGPEALKNVSRVGCDPMPDPGMGICGKNGQSMPVGVGLPTV
RIDNITVGGTKVA

Sequences:

>Translated_493_residues
MPRASAPSKRALSLKLAPPVARRPTPVALLPQPLVERLLAVAMERGGDFAEVYVERTLTTAVRLEESRIKSAQTGLVQGV
GVRVISGGKVGYAFSDDWDESALLRAASTAVMIAQGGGAERSFPVRRAAVPSHYHVSPPLMDVEVSLKTGLLMRADKAAR
AFDARVKQVNGGYVDQTRRIAVANTHGRYTEDTQDLCRISVMVVAQGTGGERRTGMYGGGGRVPFSHWDTFSPEDVAREA
ARQAVATLGAVDCVAGPQTVVLAPGWSGILLHEAVGHGLEADFIRKGTSLFAGKLGEKVASDLVTIIDDGTVSSGRGSIN
IDDEGNPGERKVLIENGVLKGYLYDSLNAQLMGQRSTGSGRRESFKHLPMPRMTNTFLAPGDHAPEDILKEVKRGLYCAT
FGGGQVDITNGNFVFEVSEAYQIEDGKLGRPVKNATLIGVGPEALKNVSRVGCDPMPDPGMGICGKNGQSMPVGVGLPTV
RIDNITVGGTKVA
>Mature_492_residues
PRASAPSKRALSLKLAPPVARRPTPVALLPQPLVERLLAVAMERGGDFAEVYVERTLTTAVRLEESRIKSAQTGLVQGVG
VRVISGGKVGYAFSDDWDESALLRAASTAVMIAQGGGAERSFPVRRAAVPSHYHVSPPLMDVEVSLKTGLLMRADKAARA
FDARVKQVNGGYVDQTRRIAVANTHGRYTEDTQDLCRISVMVVAQGTGGERRTGMYGGGGRVPFSHWDTFSPEDVAREAA
RQAVATLGAVDCVAGPQTVVLAPGWSGILLHEAVGHGLEADFIRKGTSLFAGKLGEKVASDLVTIIDDGTVSSGRGSINI
DDEGNPGERKVLIENGVLKGYLYDSLNAQLMGQRSTGSGRRESFKHLPMPRMTNTFLAPGDHAPEDILKEVKRGLYCATF
GGGQVDITNGNFVFEVSEAYQIEDGKLGRPVKNATLIGVGPEALKNVSRVGCDPMPDPGMGICGKNGQSMPVGVGLPTVR
IDNITVGGTKVA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=465, Percent_Identity=45.8064516129032, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1790682, Length=434, Percent_Identity=24.1935483870968, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 52239; Mature: 52108

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRASAPSKRALSLKLAPPVARRPTPVALLPQPLVERLLAVAMERGGDFAEVYVERTLTT
CCCCCCCCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AVRLEESRIKSAQTGLVQGVGVRVISGGKVGYAFSDDWDESALLRAASTAVMIAQGGGAE
HHHHHHHHHHHHHHHHEECCCEEEEECCEEEEEECCCCCHHHHHHHHCEEEEEEECCCCC
RSFPVRRAAVPSHYHVSPPLMDVEVSLKTGLLMRADKAARAFDARVKQVNGGYVDQTRRI
CCCCCHHHCCCCCEECCCCCEEEEEECCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCEE
AVANTHGRYTEDTQDLCRISVMVVAQGTGGERRTGMYGGGGRVPFSHWDTFSPEDVAREA
EEEECCCCCCCCHHHHHEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
ARQAVATLGAVDCVAGPQTVVLAPGWSGILLHEAVGHGLEADFIRKGTSLFAGKLGEKVA
HHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHH
SDLVTIIDDGTVSSGRGSINIDDEGNPGERKVLIENGVLKGYLYDSLNAQLMGQRSTGSG
HHHEEEEECCCCCCCCCEEEECCCCCCCCEEEEEECCEEEEEEECCCCCEEEECCCCCCC
RRESFKHLPMPRMTNTFLAPGDHAPEDILKEVKRGLYCATFGGGQVDITNGNFVFEVSEA
HHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEEECCC
YQIEDGKLGRPVKNATLIGVGPEALKNVSRVGCDPMPDPGMGICGKNGQSMPVGVGLPTV
EEECCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEECCCCEE
RIDNITVGGTKVA
EEEEEEECCCCCC
>Mature Secondary Structure 
PRASAPSKRALSLKLAPPVARRPTPVALLPQPLVERLLAVAMERGGDFAEVYVERTLTT
CCCCCCCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AVRLEESRIKSAQTGLVQGVGVRVISGGKVGYAFSDDWDESALLRAASTAVMIAQGGGAE
HHHHHHHHHHHHHHHHEECCCEEEEECCEEEEEECCCCCHHHHHHHHCEEEEEEECCCCC
RSFPVRRAAVPSHYHVSPPLMDVEVSLKTGLLMRADKAARAFDARVKQVNGGYVDQTRRI
CCCCCHHHCCCCCEECCCCCEEEEEECCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCEE
AVANTHGRYTEDTQDLCRISVMVVAQGTGGERRTGMYGGGGRVPFSHWDTFSPEDVAREA
EEEECCCCCCCCHHHHHEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
ARQAVATLGAVDCVAGPQTVVLAPGWSGILLHEAVGHGLEADFIRKGTSLFAGKLGEKVA
HHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHH
SDLVTIIDDGTVSSGRGSINIDDEGNPGERKVLIENGVLKGYLYDSLNAQLMGQRSTGSG
HHHEEEEECCCCCCCCCEEEECCCCCCCCEEEEEECCEEEEEEECCCCCEEEECCCCCCC
RRESFKHLPMPRMTNTFLAPGDHAPEDILKEVKRGLYCATFGGGQVDITNGNFVFEVSEA
HHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEEECCC
YQIEDGKLGRPVKNATLIGVGPEALKNVSRVGCDPMPDPGMGICGKNGQSMPVGVGLPTV
EEECCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEECCCCEE
RIDNITVGGTKVA
EEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]