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The map label for this gene is pmbA [H]

Identifier: 108762948

GI number: 108762948

Start: 2929320

End: 2930666

Strand: Reverse

Name: pmbA [H]

Synonym: MXAN_2518

Alternate gene names: 108762948

Gene position: 2930666-2929320 (Counterclockwise)

Preceding gene: 108757909

Following gene: 108760343

Centisome position: 32.07

GC content: 69.56

Gene sequence:

>1347_bases
ATGGACTACCAGCAGCTCGCGAAGAGAATCGTCCAGCGCGCCAAGCGCAAGGGTGCTCGCCAGGCGGAGGCCTTCCTGGA
GGTGGGCCGCCAGAGCAGCGTGCGCGTGCACCAGGGGCAGATTGAAGACCTCACCCAGTCCACCAGCAAGGGCGTGGGCG
TGCGCGTGGTGCTCAAGGACCGTCTGGGCTTCGCCTATACGTCCGACTTCGAGCCCTCCGCCGTGGACCACATCGTGGAC
CAGGCACTGAAGCTGGCCGAGTTCTCCGCCCCCAGCAAGCTCAACGGCCTGCCCTCCGGCAAGGATTTGGGCCGCTTCGG
GGACACCGGCCTGCTCTTCGACACGAAGGTGGCCGAGCTTCCCGGAGACTGGAAGATCAAGACGGCGCTGGAGGTGGAGA
AGGCGGCCCGGGCGGAGGACTCGCGCATCATCGCCTTCAACGGCGTGGGCGCCGGGGACTACGTGTCCGAGGTGTACATG
GCCTCCACCGAGGGCGTGACGGGCGCGTACTCCGGCACCTACGTGTACCTGTACGCCGCGCCGGTGGCCTCCGACGGCAA
CGGGCTCCAGACGGGTTACTGGATGGACTACCGCCGCTTCCTGGATGACCTGGACGGGCCGGAGTCCATCGGCCGGGAGG
CCACGCGCCGCGCGGTGCGGATGCTGGGCGCGAAGCGGGTGAAGACGCAGCAGGTGCCCGTGTTGTTCGACCCGCAGGTG
GCCGCCTCCTTCGTGTCGGACGTGGCGGGCGCGGCGGACGGCAACGCCGTGTACCAGAAGGCCAGCCTCCTGGCCTCGCT
GCTGGGCAAGCGGCTGGCGGGCGCGCACGTCACGTTGGTGGATGACGGCCTCATGCCGCGCGGACTGGCCACCGCGCCCT
TCGACGGCGAGGGCGTGCCCACGCGGCGCACCCCCATCATCGAGCAGGGCGTGCTCAAGTCCTTCCTCTACGACGCGTTC
ACCGCTCGCAAGGCGAAGGCCCGCACCACCGGCAACGCGTCACGCAGCTACAACGGGCTGCCCTCCATCGGAACCAGCAA
CCTGTACCTGGAGGCGGGCACGAAGTCGCCGGAGGAGCTGCTGCGCGAGGTGGACAGCGGCTTCTATGTCACCGCCCTGC
TCGGCCACGGCACCGACCCGGTGACGGGCGAGCTGTCCGCGGGCGCCAACGGCCTGTGGATTGAGAAGGGCGAGCTGACG
CACCCCGTGCAGGAGGTGACGGTGGCAGGCAGCCTGCTGCAGATGCTCAAGGACCTGGACGGCGTCGGCAGCGACCTCCA
GTTCCGCAGCGGCGCGGTGGGCGCGCCCACTGTCCGCTTCCGGCAGCTCACCGTCTCAGGCGAGTAG

Upstream 100 bases:

>100_bases
GAATGGCCAGTCCATGCCCGTGGGCGTGGGGCTGCCCACCGTGCGCATCGACAACATCACCGTTGGCGGAACCAAGGTCG
CCTGAGAGAGAGCACCAACC

Downstream 100 bases:

>100_bases
CCCACCCTTCCACGTCCCCCTACCGTGCGCCGGCGGGGGGACGTGTCAGGGCCTCCTCGTAGAACGCTTCAAGCAGCACG
AGGAGGGTGCGCCCATGGCA

Product: pmbA/tldD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MDYQQLAKRIVQRAKRKGARQAEAFLEVGRQSSVRVHQGQIEDLTQSTSKGVGVRVVLKDRLGFAYTSDFEPSAVDHIVD
QALKLAEFSAPSKLNGLPSGKDLGRFGDTGLLFDTKVAELPGDWKIKTALEVEKAARAEDSRIIAFNGVGAGDYVSEVYM
ASTEGVTGAYSGTYVYLYAAPVASDGNGLQTGYWMDYRRFLDDLDGPESIGREATRRAVRMLGAKRVKTQQVPVLFDPQV
AASFVSDVAGAADGNAVYQKASLLASLLGKRLAGAHVTLVDDGLMPRGLATAPFDGEGVPTRRTPIIEQGVLKSFLYDAF
TARKAKARTTGNASRSYNGLPSIGTSNLYLEAGTKSPEELLREVDSGFYVTALLGHGTDPVTGELSAGANGLWIEKGELT
HPVQEVTVAGSLLQMLKDLDGVGSDLQFRSGAVGAPTVRFRQLTVSGE

Sequences:

>Translated_448_residues
MDYQQLAKRIVQRAKRKGARQAEAFLEVGRQSSVRVHQGQIEDLTQSTSKGVGVRVVLKDRLGFAYTSDFEPSAVDHIVD
QALKLAEFSAPSKLNGLPSGKDLGRFGDTGLLFDTKVAELPGDWKIKTALEVEKAARAEDSRIIAFNGVGAGDYVSEVYM
ASTEGVTGAYSGTYVYLYAAPVASDGNGLQTGYWMDYRRFLDDLDGPESIGREATRRAVRMLGAKRVKTQQVPVLFDPQV
AASFVSDVAGAADGNAVYQKASLLASLLGKRLAGAHVTLVDDGLMPRGLATAPFDGEGVPTRRTPIIEQGVLKSFLYDAF
TARKAKARTTGNASRSYNGLPSIGTSNLYLEAGTKSPEELLREVDSGFYVTALLGHGTDPVTGELSAGANGLWIEKGELT
HPVQEVTVAGSLLQMLKDLDGVGSDLQFRSGAVGAPTVRFRQLTVSGE
>Mature_448_residues
MDYQQLAKRIVQRAKRKGARQAEAFLEVGRQSSVRVHQGQIEDLTQSTSKGVGVRVVLKDRLGFAYTSDFEPSAVDHIVD
QALKLAEFSAPSKLNGLPSGKDLGRFGDTGLLFDTKVAELPGDWKIKTALEVEKAARAEDSRIIAFNGVGAGDYVSEVYM
ASTEGVTGAYSGTYVYLYAAPVASDGNGLQTGYWMDYRRFLDDLDGPESIGREATRRAVRMLGAKRVKTQQVPVLFDPQV
AASFVSDVAGAADGNAVYQKASLLASLLGKRLAGAHVTLVDDGLMPRGLATAPFDGEGVPTRRTPIIEQGVLKSFLYDAF
TARKAKARTTGNASRSYNGLPSIGTSNLYLEAGTKSPEELLREVDSGFYVTALLGHGTDPVTGELSAGANGLWIEKGELT
HPVQEVTVAGSLLQMLKDLDGVGSDLQFRSGAVGAPTVRFRQLTVSGE

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1790682, Length=417, Percent_Identity=30.4556354916067, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1789640, Length=472, Percent_Identity=25.635593220339, Blast_Score=122, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 47918; Mature: 47918

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYQQLAKRIVQRAKRKGARQAEAFLEVGRQSSVRVHQGQIEDLTQSTSKGVGVRVVLKD
CCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCEEEEEEEC
RLGFAYTSDFEPSAVDHIVDQALKLAEFSAPSKLNGLPSGKDLGRFGDTGLLFDTKVAEL
CCCCEEECCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCEEECHHHHC
PGDWKIKTALEVEKAARAEDSRIIAFNGVGAGDYVSEVYMASTEGVTGAYSGTYVYLYAA
CCCCEEEHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
PVASDGNGLQTGYWMDYRRFLDDLDGPESIGREATRRAVRMLGAKRVKTQQVPVLFDPQV
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHH
AASFVSDVAGAADGNAVYQKASLLASLLGKRLAGAHVTLVDDGLMPRGLATAPFDGEGVP
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCC
TRRTPIIEQGVLKSFLYDAFTARKAKARTTGNASRSYNGLPSIGTSNLYLEAGTKSPEEL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHH
LREVDSGFYVTALLGHGTDPVTGELSAGANGLWIEKGELTHPVQEVTVAGSLLQMLKDLD
HHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHC
GVGSDLQFRSGAVGAPTVRFRQLTVSGE
CCCCCCEECCCCCCCCCEEEEEEEECCC
>Mature Secondary Structure
MDYQQLAKRIVQRAKRKGARQAEAFLEVGRQSSVRVHQGQIEDLTQSTSKGVGVRVVLKD
CCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCEEEEEEEC
RLGFAYTSDFEPSAVDHIVDQALKLAEFSAPSKLNGLPSGKDLGRFGDTGLLFDTKVAEL
CCCCEEECCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCEEECHHHHC
PGDWKIKTALEVEKAARAEDSRIIAFNGVGAGDYVSEVYMASTEGVTGAYSGTYVYLYAA
CCCCEEEHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
PVASDGNGLQTGYWMDYRRFLDDLDGPESIGREATRRAVRMLGAKRVKTQQVPVLFDPQV
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHH
AASFVSDVAGAADGNAVYQKASLLASLLGKRLAGAHVTLVDDGLMPRGLATAPFDGEGVP
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCC
TRRTPIIEQGVLKSFLYDAFTARKAKARTTGNASRSYNGLPSIGTSNLYLEAGTKSPEEL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHH
LREVDSGFYVTALLGHGTDPVTGELSAGANGLWIEKGELTHPVQEVTVAGSLLQMLKDLD
HHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHC
GVGSDLQFRSGAVGAPTVRFRQLTVSGE
CCCCCCEECCCCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]