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The map label for this gene is ruvC

Identifier: 108757135

GI number: 108757135

Start: 6219901

End: 6220476

Strand: Reverse

Name: ruvC

Synonym: MXAN_4973

Alternate gene names: 108757135

Gene position: 6220476-6219901 (Counterclockwise)

Preceding gene: 108761477

Following gene: 108762337

Centisome position: 68.06

GC content: 73.78

Gene sequence:

>576_bases
GTGCGCGTGCTTGGCGTTGACCCGGGAAGCCGGTTCATGGGCTTCGGGGTGGTGGAGGAGAAGCGGGGCCGGCTGGTGCA
CGTGGGCCACGGTGTCATCAAGGGCGATCCGGCGTTGCCGCTGTCGGACCGCCTGCGGGACTTGCACGGCGCGCTGACGG
CGGCCCTGGTGAAATACCGCCCGGCCGCGGTGGCGGTGGAAGGCGTGTTCACCTTCCGCAACGCACGCAGCGCACTGGTG
CTGGGGCATGCGCGCGGCGTCGCGCTGCTGGCGGCGGCGCAGGCGGGGCTGCCCGTCTTCGAATACGCGCCGGCGAAGGT
GAAGAAGGCGGTGGGGGCGGGCGGCGCGGACGGGAAGGACGCAGTGGCGCGGATGGTGCGGACCTTCCTGGAGCTGGATG
CGTCGGTGCTGGAGCGCGCGGACGCGAGTGATGCGCTGGCGGTGGCGCTGTGCCACCTCAACCATGGGCGGGCCGCGGTA
CCGGCGGCGTCCGCGTCGGGCAAGAAGCGCAAGGGCGCGGCGGCGCTGCTGGCGGACCGGCTGGCGCCCGCGTACCGGCG
TCCGGAGGCGAGATGA

Upstream 100 bases:

>100_bases
GGAGAACGACGACGTGCAGAACGTGCACGGGAACTACGAAATCGAAGACGCGATGCTGGATTCGTTGTTGCAGTAGCGGA
GTCCTGGAACGGAGTGGAAC

Downstream 100 bases:

>100_bases
TTTCGCGGTTGCGTGGGACGGTGTTGGAGAAGGACCTGGAGGACGCCACCATCGACGTGGGCGGCGTGGGTTACCGGGTG
AACTTCTCCTCACTGGCGCT

Product: crossover junction endodeoxyribonuclease RuvC

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MRVLGVDPGSRFMGFGVVEEKRGRLVHVGHGVIKGDPALPLSDRLRDLHGALTAALVKYRPAAVAVEGVFTFRNARSALV
LGHARGVALLAAAQAGLPVFEYAPAKVKKAVGAGGADGKDAVARMVRTFLELDASVLERADASDALAVALCHLNHGRAAV
PAASASGKKRKGAAALLADRLAPAYRRPEAR

Sequences:

>Translated_191_residues
MRVLGVDPGSRFMGFGVVEEKRGRLVHVGHGVIKGDPALPLSDRLRDLHGALTAALVKYRPAAVAVEGVFTFRNARSALV
LGHARGVALLAAAQAGLPVFEYAPAKVKKAVGAGGADGKDAVARMVRTFLELDASVLERADASDALAVALCHLNHGRAAV
PAASASGKKRKGAAALLADRLAPAYRRPEAR
>Mature_191_residues
MRVLGVDPGSRFMGFGVVEEKRGRLVHVGHGVIKGDPALPLSDRLRDLHGALTAALVKYRPAAVAVEGVFTFRNARSALV
LGHARGVALLAAAQAGLPVFEYAPAKVKKAVGAGGADGKDAVARMVRTFLELDASVLERADASDALAVALCHLNHGRAAV
PAASASGKKRKGAAALLADRLAPAYRRPEAR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=154, Percent_Identity=40.2597402597403, Blast_Score=107, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_MYXXD (Q1D2J4)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_633129.1
- ProteinModelPortal:   Q1D2J4
- SMR:   Q1D2J4
- STRING:   Q1D2J4
- GeneID:   4105281
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_4973
- TIGR:   MXAN_4973
- eggNOG:   COG0817
- HOGENOM:   HBG437552
- OMA:   RTGWGVI
- PhylomeDB:   Q1D2J4
- BioCyc:   MXAN246197:MXAN_4973-MONOMER
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 19826; Mature: 19826

Theoretical pI: Translated: 11.08; Mature: 11.08

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGVDPGSRFMGFGVVEEKRGRLVHVGHGVIKGDPALPLSDRLRDLHGALTAALVKYR
CEEEECCCCCCCEECCCEECCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHC
PAAVAVEGVFTFRNARSALVLGHARGVALLAAAQAGLPVFEYAPAKVKKAVGAGGADGKD
CHHEEHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHH
AVARMVRTFLELDASVLERADASDALAVALCHLNHGRAAVPAASASGKKRKGAAALLADR
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LAPAYRRPEAR
HHHHHCCCCCC
>Mature Secondary Structure
MRVLGVDPGSRFMGFGVVEEKRGRLVHVGHGVIKGDPALPLSDRLRDLHGALTAALVKYR
CEEEECCCCCCCEECCCEECCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHC
PAAVAVEGVFTFRNARSALVLGHARGVALLAAAQAGLPVFEYAPAKVKKAVGAGGADGKD
CHHEEHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHH
AVARMVRTFLELDASVLERADASDALAVALCHLNHGRAAVPAASASGKKRKGAAALLADR
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LAPAYRRPEAR
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA