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The map label for this gene is ruvA

Identifier: 108762337

GI number: 108762337

Start: 6219296

End: 6219904

Strand: Reverse

Name: ruvA

Synonym: MXAN_4972

Alternate gene names: 108762337

Gene position: 6219904-6219296 (Counterclockwise)

Preceding gene: 108757135

Following gene: 108762446

Centisome position: 68.05

GC content: 69.13

Gene sequence:

>609_bases
ATGATTTCGCGGTTGCGTGGGACGGTGTTGGAGAAGGACCTGGAGGACGCCACCATCGACGTGGGCGGCGTGGGTTACCG
GGTGAACTTCTCCTCACTGGCGCTGGGGAAGCTGCCGGCGGAGGGACAGCCGGTGGACGTGCGCGTGCGCACCGTGGTGC
GCGAGGACGCCTTCGACCTCTTCGGCTTCCTGACGAAGGGCGAGGAAGAGGTGTTCCTGCTGCTCAACAGCGTCTCGCGG
GTGGGACCCCGGCTGTCGTTGATGGTGCTGTCCGGCATGGAGGTGCCGGAGCTGGTGGCGGCGCTGTCGCGGGGCGAGGT
GGCGCGGCTGGCGAAGATTCACGGCGTGGGCAAGAAGACCGCCGAGCGGCTGGTGCTGGAGCTCAAGGACAAGGTGAAGA
CGATTCACCTGGAAGCGGTGTCGCGCGGGACCGCGCCGGCCGCCGTCAGTGGAGCCCATGCGGACCTGGTCTCCGCGCTG
CTCAACCTTGGCTACAAGCAGCCCCAGGCGGAGAAGGCCGCGGACCTGGCCAGCGAACGGCTGGGGGCGGAGGCCACCTT
CCAGGCGCTGTTCCGCGAGGCCCTCAAGGCGCTCCGCTCGGGCGGCTGA

Upstream 100 bases:

>100_bases
CCGCGGTACCGGCGGCGTCCGCGTCGGGCAAGAAGCGCAAGGGCGCGGCGGCGCTGCTGGCGGACCGGCTGGCGCCCGCG
TACCGGCGTCCGGAGGCGAG

Downstream 100 bases:

>100_bases
TCGCTGCGACACATCGGGTGTGACGGCGCTGTGACGGCAAAATCCGGGAGAACGGCTGGGCCGTACCGTCCTCTCTCCCG
TTGAGAGCTTGAAAGACGCT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MISRLRGTVLEKDLEDATIDVGGVGYRVNFSSLALGKLPAEGQPVDVRVRTVVREDAFDLFGFLTKGEEEVFLLLNSVSR
VGPRLSLMVLSGMEVPELVAALSRGEVARLAKIHGVGKKTAERLVLELKDKVKTIHLEAVSRGTAPAAVSGAHADLVSAL
LNLGYKQPQAEKAADLASERLGAEATFQALFREALKALRSGG

Sequences:

>Translated_202_residues
MISRLRGTVLEKDLEDATIDVGGVGYRVNFSSLALGKLPAEGQPVDVRVRTVVREDAFDLFGFLTKGEEEVFLLLNSVSR
VGPRLSLMVLSGMEVPELVAALSRGEVARLAKIHGVGKKTAERLVLELKDKVKTIHLEAVSRGTAPAAVSGAHADLVSAL
LNLGYKQPQAEKAADLASERLGAEATFQALFREALKALRSGG
>Mature_202_residues
MISRLRGTVLEKDLEDATIDVGGVGYRVNFSSLALGKLPAEGQPVDVRVRTVVREDAFDLFGFLTKGEEEVFLLLNSVSR
VGPRLSLMVLSGMEVPELVAALSRGEVARLAKIHGVGKKTAERLVLELKDKVKTIHLEAVSRGTAPAAVSGAHADLVSAL
LNLGYKQPQAEKAADLASERLGAEATFQALFREALKALRSGG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=204, Percent_Identity=42.6470588235294, Blast_Score=135, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_MYXXD (Q1D2J5)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_633128.1
- ProteinModelPortal:   Q1D2J5
- SMR:   Q1D2J5
- STRING:   Q1D2J5
- GeneID:   4106083
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_4972
- TIGR:   MXAN_4972
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   AQRIVLD
- PhylomeDB:   Q1D2J5
- BioCyc:   MXAN246197:MXAN_4972-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21559; Mature: 21559

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISRLRGTVLEKDLEDATIDVGGVGYRVNFSSLALGKLPAEGQPVDVRVRTVVREDAFDL
CCCHHHHHHHHHCCCCCEEEECCCEEEEEHHHEECCCCCCCCCCEEHHHHHHHHHHHHHH
FGFLTKGEEEVFLLLNSVSRVGPRLSLMVLSGMEVPELVAALSRGEVARLAKIHGVGKKT
HHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHCCCHHH
AERLVLELKDKVKTIHLEAVSRGTAPAAVSGAHADLVSALLNLGYKQPQAEKAADLASER
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LGAEATFQALFREALKALRSGG
HCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MISRLRGTVLEKDLEDATIDVGGVGYRVNFSSLALGKLPAEGQPVDVRVRTVVREDAFDL
CCCHHHHHHHHHCCCCCEEEECCCEEEEEHHHEECCCCCCCCCCEEHHHHHHHHHHHHHH
FGFLTKGEEEVFLLLNSVSRVGPRLSLMVLSGMEVPELVAALSRGEVARLAKIHGVGKKT
HHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHCCCHHH
AERLVLELKDKVKTIHLEAVSRGTAPAAVSGAHADLVSALLNLGYKQPQAEKAADLASER
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LGAEATFQALFREALKALRSGG
HCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA