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The map label for this gene is pitB [C]

Identifier: 108563847

GI number: 108563847

Start: 1478558

End: 1480159

Strand: Direct

Name: pitB [C]

Synonym: HPAG1_1422

Alternate gene names: 108563847

Gene position: 1478558-1480159 (Clockwise)

Preceding gene: 108563836

Following gene: 108563848

Centisome position: 92.62

GC content: 43.26

Gene sequence:

>1602_bases
ATGGAAATTAAAAACATCAAAGAGTTTGAAAAAGCTTCCAAAAAACTCCAAAAAGACACTTTAAAGATCGCTCTCGCTCT
TTTGTTTCTCATTGGCGCTGCTTTGCTCGCTCTTATTTTTGGGCAGGCTAATTCTAAGGGATTGTTGCTCATTTTTGCGG
CTGTGATTGGGGGGTATATGGCGATGAATATTGGTGCGAATGATGTGTCTAATAATGTCGGCCCTGCCGTAGGCTCTAAA
GCCATTAGCATGGGCGGGGCGATTTTGATTGCCGGGATTTGTGAAATGCTTGGGGCGATCATTGCTGGGGGGGAAGTGGT
TTCTACGATTAAGGGCCGTATCGTTTCGCCTGAATCCATTAATGATGCGCATGTTTTCATTAATGTCATGTTGGCTAGCT
TGCTCAGTGGGGCGTTGTGGTTGCATGTAGCGACTTTAATTGGCGCTCCTGTTTCCACTTCACACTCTGTGGTGGGGGGG
ATTATGGGGGCTGGAATGGCAGCAGCTGGAATGGCAGCGGTCAATTGGCATTTTTTATCAGGCATTGTAGCGAGTTGGGT
AATTTCGCCTTTAATGGGGGCTTTGATAGCCATGTTTTTTTTAATGCTCATTAAAAAGACTATCGCTTATAAAGAAGATA
AAAAGAGCGCGGCTTTAAAGGTCGTGCCTTATTTGGTAGCGTTGATGAGCTTAACATTCAGCTGGTATTTGATTATTAAG
GTTTTAAAACGCCTCTATGCGGTGGGTTTTGAAATCCAACTGGCTTGTGGCTGTATCCTTGCGCTTTTAATCTTTATTCT
TTTTAAAAGATTTGTGTTAAAAAAAGCCCCGCAATTAGAAAACAGCCATGAAAGCATTAATGAGCTTTTCAATGTCCCTT
TGATTTTTGCCGCCGCGCTTTTAAGCTTTGCGCATGGGGCTAATGATGTGGCTAACGCTATAGGCCCTTTAGCGGCTATC
AGTCAAACTTTAGAAGATGCAAATAGCCCTATAGGGAATACTTTAAGCTCTGTGCCGTTGTGGATTATGGTAGTAGGGGC
GGCTGGGATTGCTTTAGGCTTGAGTTTGTATGGGCCAAAGCTCATTAAAACGGTGGGGTCAGAAATCACAGAATTAGACA
AAATGCAAGCCTTTTGCATCGCGCTTTCTGCAGTCATCACCGTGCTTTTAGCCTCTCAATTAGGCTTGCCCGTAAGCTCT
ACGCATATTGTGGTGGGCGCGGTGTTTGGGGTGGGCTTTTTAAGAGAGCGCTTAAGAGAGCAATCAAGAAGGCGTTTTGC
TAGGATCAGAGACAACATTGTAGCGGCGCACTTTGGGGAAGATTTAGAAGAAATTGAAGGTTTTTTAGAGCGCTTTGATA
AAGCCAATTTGAAAGAAAAATCGCTCATGCTAGAGAGCTTGAAAAAAAGCAAGAACACCGCTATCGCTTTGGAATTGAAA
AAGAAAGAAAAAAAGTCGCTTAAAAAAGTGTATAAAGAAGAGGTGATCAAACGCTCCATTTTAAAAAAGATTGTTACCGC
TTGGTTGGTAACTGTGCCGGTTTCTGCGCTTTTGGGGGCGCTTCTGTTTGTGGCTCTTGGTTTTATAGAAAAGTATTTCT
AG

Upstream 100 bases:

>100_bases
ATATAATGAGCCATTTTTATCAAACAACGCTTTTTAAGAGTGGCTCAAGGGCTAATTGGATAGAATGAGACCACTATTAG
AATAAGGTTTTTATGACGAT

Downstream 100 bases:

>100_bases
GGTTTTTAAAGGCTTGATTTTTAAAGTTAGGCTTAATCTTTTATGTTAAAATTCTGAGATTTTATATTTATATTTTATCT
TTATCGTTAGGTTTTAGGTT

Product: phosphate permease

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MEIKNIKEFEKASKKLQKDTLKIALALLFLIGAALLALIFGQANSKGLLLIFAAVIGGYMAMNIGANDVSNNVGPAVGSK
AISMGGAILIAGICEMLGAIIAGGEVVSTIKGRIVSPESINDAHVFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGG
IMGAGMAAAGMAAVNWHFLSGIVASWVISPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLTFSWYLIIK
VLKRLYAVGFEIQLACGCILALLIFILFKRFVLKKAPQLENSHESINELFNVPLIFAAALLSFAHGANDVANAIGPLAAI
SQTLEDANSPIGNTLSSVPLWIMVVGAAGIALGLSLYGPKLIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSS
THIVVGAVFGVGFLRERLREQSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELK
KKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGALLFVALGFIEKYF

Sequences:

>Translated_533_residues
MEIKNIKEFEKASKKLQKDTLKIALALLFLIGAALLALIFGQANSKGLLLIFAAVIGGYMAMNIGANDVSNNVGPAVGSK
AISMGGAILIAGICEMLGAIIAGGEVVSTIKGRIVSPESINDAHVFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGG
IMGAGMAAAGMAAVNWHFLSGIVASWVISPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLTFSWYLIIK
VLKRLYAVGFEIQLACGCILALLIFILFKRFVLKKAPQLENSHESINELFNVPLIFAAALLSFAHGANDVANAIGPLAAI
SQTLEDANSPIGNTLSSVPLWIMVVGAAGIALGLSLYGPKLIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSS
THIVVGAVFGVGFLRERLREQSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELK
KKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGALLFVALGFIEKYF
>Mature_533_residues
MEIKNIKEFEKASKKLQKDTLKIALALLFLIGAALLALIFGQANSKGLLLIFAAVIGGYMAMNIGANDVSNNVGPAVGSK
AISMGGAILIAGICEMLGAIIAGGEVVSTIKGRIVSPESINDAHVFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGG
IMGAGMAAAGMAAVNWHFLSGIVASWVISPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLTFSWYLIIK
VLKRLYAVGFEIQLACGCILALLIFILFKRFVLKKAPQLENSHESINELFNVPLIFAAALLSFAHGANDVANAIGPLAAI
SQTLEDANSPIGNTLSSVPLWIMVVGAAGIALGLSLYGPKLIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSS
THIVVGAVFGVGFLRERLREQSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELK
KKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGALLFVALGFIEKYF

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=140, Percent_Identity=37.8571428571429, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI5803173, Length=132, Percent_Identity=38.6363636363636, Blast_Score=103, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71981576, Length=424, Percent_Identity=31.3679245283019, Blast_Score=161, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17557328, Length=482, Percent_Identity=25.9336099585062, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25146401, Length=154, Percent_Identity=37.6623376623377, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17539280, Length=191, Percent_Identity=34.0314136125654, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32566716, Length=180, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17536725, Length=148, Percent_Identity=28.3783783783784, Blast_Score=82, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6319773, Length=142, Percent_Identity=36.6197183098592, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21356511, Length=253, Percent_Identity=30.4347826086957, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 57104; Mature: 57104

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKNIKEFEKASKKLQKDTLKIALALLFLIGAALLALIFGQANSKGLLLIFAAVIGGYM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AMNIGANDVSNNVGPAVGSKAISMGGAILIAGICEMLGAIIAGGEVVSTIKGRIVSPESI
EEECCCHHHCCCCCCHHCHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCC
NDAHVFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGGIMGAGMAAAGMAAVNWHFLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GIVASWVISPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLTFSWYLIIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLKRLYAVGFEIQLACGCILALLIFILFKRFVLKKAPQLENSHESINELFNVPLIFAAAL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHH
LSFAHGANDVANAIGPLAAISQTLEDANSPIGNTLSSVPLWIMVVGAAGIALGLSLYGPK
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHH
LIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSSTHIVVGAVFGVGFLRERLRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
QSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEH
KKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGALLFVALGFIEKYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIKNIKEFEKASKKLQKDTLKIALALLFLIGAALLALIFGQANSKGLLLIFAAVIGGYM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AMNIGANDVSNNVGPAVGSKAISMGGAILIAGICEMLGAIIAGGEVVSTIKGRIVSPESI
EEECCCHHHCCCCCCHHCHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCC
NDAHVFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGGIMGAGMAAAGMAAVNWHFLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GIVASWVISPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLTFSWYLIIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLKRLYAVGFEIQLACGCILALLIFILFKRFVLKKAPQLENSHESINELFNVPLIFAAAL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHH
LSFAHGANDVANAIGPLAAISQTLEDANSPIGNTLSSVPLWIMVVGAAGIALGLSLYGPK
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHH
LIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSSTHIVVGAVFGVGFLRERLRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
QSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEH
KKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGALLFVALGFIEKYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]