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The map label for this gene is hypD2 [H]

Identifier: 108563303

GI number: 108563303

Start: 916954

End: 918066

Strand: Reverse

Name: hypD2 [H]

Synonym: HPAG1_0878

Alternate gene names: 108563303

Gene position: 918066-916954 (Counterclockwise)

Preceding gene: 108563304

Following gene: 108563301

Centisome position: 57.51

GC content: 44.29

Gene sequence:

>1113_bases
ATGAGCGTTGATCACCTCATTTCGCCCTTTAGGGACAAGCGAATTATTTTAGCGCTCTCTAATGCAATCAAAAAACTCGC
TTTCAAACTTGAAAAAAAATTAGTCATCATGGAAGTGTGCGGAGGGCATACGCATTCTATCATGAAATACGGGCTTTTGG
ATTTGATGCCTAACAATTTAGAGTTTGTGCATGGGCCAGGGTGTCCGGTATGCGTGATGCCAAGAGCGCGCCTTGATGAA
GCTTATGAACTCGCTAGCATGAAAGATAGCATTGTTTTAAGCTTAGGGGATATGATGAAAGTCCCAGGGAGCTATGGGAG
TTTGATACAAGCCAGAGAAAAGGGGCTGGATGCGCGCTTTTTGTATTCGCCCATGCAAGCTTTAGAGATCGCTAAAGAAA
ACCCGCATAAAAAAGTCATTTATATTGCGATCGGTTTTGAAACCACCACGCCCATGACAGCGAGCGTCTTACTCAATGCC
AAAAAAGAAAAAATTAACAATCTTTTTTTCCACACCAACCACCTTTTAGTGCCTCCTAGCGTGAGCGCGATTTTAAAAGA
TCCAGCATGCCAGATTAACGCTCTTTTAGCCCCTAGCCATGTGAGCGTGATCAGCGGCGCTCAAATCTACGCTCCTTTAG
TGGATCGCTTTAAACTCCCCATTATCGTGAGCGGTTTTGAGCCGGTGGATATATTAGAAAGCGTGCTGATGCTTCTTAAA
CAAGCCTTAAACAAAGAAGCCAAGCTAGAAATCCAATACAAAAGAGCGGTGAGCTATGAAGGGAATGTGAAAGCGCAAGA
GTTAGTCAATGCTTGCATGGAAGTTAGGGAAAATTTTGAATGGAGAGGTTTGGGGAATATCAAACATTCCGCCCTAAAGC
TCAAAGAAGCGTTCGCTTCTTATGACGCTGAAAAAGTCTTTAAAGAATATTTAAGCCACAAAACCTCTAAAGAAAACAAA
GCATGCAAGTGTGGGGAGATCTTAAAAGGCATCGCTAAGCCCCTAGACTGCTCATTATTCGCTACAATTTGCACCCCGCA
AAACCCGATCGGCAGTTGCATGGTCAGCTCTGAGGGGGCGTGCGCGGCGTATTATCGTTACAAGCGCGTTTGA

Upstream 100 bases:

>100_bases
GTAAGATTGATGAAAAAGAAGCCCTAGAATCCATTGAGCTTTATCAAGAAATGATCGCCAAAATGAACGAAACGCATGAA
TAAACGCATGCATAAAAACA

Downstream 100 bases:

>100_bases
GTTTTAAAAATTGCTTTTTAGTGAAATCGCTCAAACCTTCGCAATTGACATTCACGCTTTTAGGGGGTTTTTCTTTTTTA
ACAACTGGTTTTTGATAAGC

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSVDHLISPFRDKRIILALSNAIKKLAFKLEKKLVIMEVCGGHTHSIMKYGLLDLMPNNLEFVHGPGCPVCVMPRARLDE
AYELASMKDSIVLSLGDMMKVPGSYGSLIQAREKGLDARFLYSPMQALEIAKENPHKKVIYIAIGFETTTPMTASVLLNA
KKEKINNLFFHTNHLLVPPSVSAILKDPACQINALLAPSHVSVISGAQIYAPLVDRFKLPIIVSGFEPVDILESVLMLLK
QALNKEAKLEIQYKRAVSYEGNVKAQELVNACMEVRENFEWRGLGNIKHSALKLKEAFASYDAEKVFKEYLSHKTSKENK
ACKCGEILKGIAKPLDCSLFATICTPQNPIGSCMVSSEGACAAYYRYKRV

Sequences:

>Translated_370_residues
MSVDHLISPFRDKRIILALSNAIKKLAFKLEKKLVIMEVCGGHTHSIMKYGLLDLMPNNLEFVHGPGCPVCVMPRARLDE
AYELASMKDSIVLSLGDMMKVPGSYGSLIQAREKGLDARFLYSPMQALEIAKENPHKKVIYIAIGFETTTPMTASVLLNA
KKEKINNLFFHTNHLLVPPSVSAILKDPACQINALLAPSHVSVISGAQIYAPLVDRFKLPIIVSGFEPVDILESVLMLLK
QALNKEAKLEIQYKRAVSYEGNVKAQELVNACMEVRENFEWRGLGNIKHSALKLKEAFASYDAEKVFKEYLSHKTSKENK
ACKCGEILKGIAKPLDCSLFATICTPQNPIGSCMVSSEGACAAYYRYKRV
>Mature_369_residues
SVDHLISPFRDKRIILALSNAIKKLAFKLEKKLVIMEVCGGHTHSIMKYGLLDLMPNNLEFVHGPGCPVCVMPRARLDEA
YELASMKDSIVLSLGDMMKVPGSYGSLIQAREKGLDARFLYSPMQALEIAKENPHKKVIYIAIGFETTTPMTASVLLNAK
KEKINNLFFHTNHLLVPPSVSAILKDPACQINALLAPSHVSVISGAQIYAPLVDRFKLPIIVSGFEPVDILESVLMLLKQ
ALNKEAKLEIQYKRAVSYEGNVKAQELVNACMEVRENFEWRGLGNIKHSALKLKEAFASYDAEKVFKEYLSHKTSKENKA
CKCGEILKGIAKPLDCSLFATICTPQNPIGSCMVSSEGACAAYYRYKRV

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=367, Percent_Identity=43.3242506811989, Blast_Score=343, Evalue=8e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 41051; Mature: 40920

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDHLISPFRDKRIILALSNAIKKLAFKLEKKLVIMEVCGGHTHSIMKYGLLDLMPNNL
CCHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHCCCCC
EFVHGPGCPVCVMPRARLDEAYELASMKDSIVLSLGDMMKVPGSYGSLIQAREKGLDARF
CEEECCCCCEEECCHHHHHHHHHHHHCCCHHEEEHHHHHHCCCCHHHHHHHHHCCCCHHH
LYSPMQALEIAKENPHKKVIYIAIGFETTTPMTASVLLNAKKEKINNLFFHTNHLLVPPS
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHEEECCCEECCCC
VSAILKDPACQINALLAPSHVSVISGAQIYAPLVDRFKLPIIVSGFEPVDILESVLMLLK
HHHHHCCCCHHEEEEECCCHHHHHCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
QALNKEAKLEIQYKRAVSYEGNVKAQELVNACMEVRENFEWRGLGNIKHSALKLKEAFAS
HHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC
YDAEKVFKEYLSHKTSKENKACKCGEILKGIAKPLDCSLFATICTPQNPIGSCMVSSEGA
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEECCCCC
CAAYYRYKRV
EEEHHHHHCC
>Mature Secondary Structure 
SVDHLISPFRDKRIILALSNAIKKLAFKLEKKLVIMEVCGGHTHSIMKYGLLDLMPNNL
CHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHCCCCC
EFVHGPGCPVCVMPRARLDEAYELASMKDSIVLSLGDMMKVPGSYGSLIQAREKGLDARF
CEEECCCCCEEECCHHHHHHHHHHHHCCCHHEEEHHHHHHCCCCHHHHHHHHHCCCCHHH
LYSPMQALEIAKENPHKKVIYIAIGFETTTPMTASVLLNAKKEKINNLFFHTNHLLVPPS
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHEEECCCEECCCC
VSAILKDPACQINALLAPSHVSVISGAQIYAPLVDRFKLPIIVSGFEPVDILESVLMLLK
HHHHHCCCCHHEEEEECCCHHHHHCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
QALNKEAKLEIQYKRAVSYEGNVKAQELVNACMEVRENFEWRGLGNIKHSALKLKEAFAS
HHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC
YDAEKVFKEYLSHKTSKENKACKCGEILKGIAKPLDCSLFATICTPQNPIGSCMVSSEGA
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEECCCCC
CAAYYRYKRV
EEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275; 8510650 [H]