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The map label for this gene is murA [H]

Identifier: 108563058

GI number: 108563058

Start: 657979

End: 659247

Strand: Direct

Name: murA [H]

Synonym: HPAG1_0633

Alternate gene names: 108563058

Gene position: 657979-659247 (Clockwise)

Preceding gene: 108563057

Following gene: 108563059

Centisome position: 41.22

GC content: 44.84

Gene sequence:

>1269_bases
TTGGATTTTTTAGAGATTGTAGGACAAGTCCCTTTAAAAGGGGGGGTAGAAATTTCAGGGGCGAAAAACTCCGCGCTCCC
CATTTTAGCCGCCACGCTTTTAAGCCGCCAAGAAGTCAAAATCAAATCTTTGCCCCAAGTGGCTGACATCAAGGCGATGG
CGTTATTGTTGCAAAATTTAGGTGCAGAATTAGAATGGCTTAACCCCCACACGCTCCAACTCAGCACTAAATCCCTGCAC
CACACCGAAGCCACTTACGATTTAGTGCGTAAAATGCGCGCTTCCATTTTGGTTTTAGGCCCTTTATTAGCGCGTTTTAA
AGAATGCTTAGTGAGTTTGCCCGGTGGGTGTGCTATAGGAGCAAGGCCTGTGGATTTGCACTTAAAAGCGATGCAACAAT
TAGGGGCTGAAATCAAAATTGAGCAAGGCTATATCCATGCAAAAGCCCCTAAAGGCTTGAAAGGGAATGATATTTTATTT
GATAAGATCAGCGTTACAGGCACAGAAAACGCCCTCATGGCCGCAAGCTTAGCTAAAGGGATCACGCGCATCATTAACGC
CGCTAAAGAGCCAGAAATCGCTCAATTGTGCGCGTTTTTACAAAGTGGGGGGGTAGAAATTGAGGGCGTTGGCAGCAGTG
AGCTAAAGATTAGGGGGGTAGAAAGCGACGCTTTAAATTTAAAAGACATTCAAATCATACCGGACAGGATTGAAGCAGGC
ACTTATTTGTGCGTGGGGGCTATCACTAACAGCCAGCTTAAAATCAATCGTATCATTCCTAACCACATTCAAGCGATCAC
CGATAAGCTTATAGAAATTGGTTTTTCGCTAGACATTCAAGAAAATTCTATAGAAATTTATCCGGCCAAAAAACGACAAG
CCTTTGAAATCACCACGAAAGAATACCCGGGTTTTCCCACAGACATGCAAGCGCAATTCATGGCGTTAGCCACGCAGTGT
TTAGGGACTAGCATCATTGAAGAGACGCTTTTTGAAAACCGCTTCATGCATGCGAGCGAGTTGCAACGATTAGGGGCTAA
TATCAGCCTAAAAACCAATGTTGCTACCATTAGCGGATCCACAGAGCTTACCGGAAGCGATGTGATGGCGACCGATTTAA
GGGCTTCTTCGGCTCTCGTTTTAGCCGCTTTAGTGGCTAAGGGGGTGAGTAGGGTGCATAGGATTTACCACTTGGATAGG
GGTTATGAGAGATTAGAGGATAAAATCAACGCTTTAGGGGCAAAAGTGTTGCGTTTAAAAGAAAAATAA

Upstream 100 bases:

>100_bases
ATTTTGGGCAAGAATTAGAAAACGCTAACCCTAATTACCAACAAAAAATCGCTAACGCTACCGGCTTAGCCCTTAAGAAT
AAAAAAGAAAAAGGATAGAA

Downstream 100 bases:

>100_bases
TCCAAGATTTGGTTACAATAGCTAGAATATTTTTCAATTATTACATAAGGAGCTTTTATGCGTATTGAGCATGATTTCAT
TGGGCAAATGGAAATTAGCG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MDFLEIVGQVPLKGGVEISGAKNSALPILAATLLSRQEVKIKSLPQVADIKAMALLLQNLGAELEWLNPHTLQLSTKSLH
HTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIGARPVDLHLKAMQQLGAEIKIEQGYIHAKAPKGLKGNDILF
DKISVTGTENALMAASLAKGITRIINAAKEPEIAQLCAFLQSGGVEIEGVGSSELKIRGVESDALNLKDIQIIPDRIEAG
TYLCVGAITNSQLKINRIIPNHIQAITDKLIEIGFSLDIQENSIEIYPAKKRQAFEITTKEYPGFPTDMQAQFMALATQC
LGTSIIEETLFENRFMHASELQRLGANISLKTNVATISGSTELTGSDVMATDLRASSALVLAALVAKGVSRVHRIYHLDR
GYERLEDKINALGAKVLRLKEK

Sequences:

>Translated_422_residues
MDFLEIVGQVPLKGGVEISGAKNSALPILAATLLSRQEVKIKSLPQVADIKAMALLLQNLGAELEWLNPHTLQLSTKSLH
HTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIGARPVDLHLKAMQQLGAEIKIEQGYIHAKAPKGLKGNDILF
DKISVTGTENALMAASLAKGITRIINAAKEPEIAQLCAFLQSGGVEIEGVGSSELKIRGVESDALNLKDIQIIPDRIEAG
TYLCVGAITNSQLKINRIIPNHIQAITDKLIEIGFSLDIQENSIEIYPAKKRQAFEITTKEYPGFPTDMQAQFMALATQC
LGTSIIEETLFENRFMHASELQRLGANISLKTNVATISGSTELTGSDVMATDLRASSALVLAALVAKGVSRVHRIYHLDR
GYERLEDKINALGAKVLRLKEK
>Mature_422_residues
MDFLEIVGQVPLKGGVEISGAKNSALPILAATLLSRQEVKIKSLPQVADIKAMALLLQNLGAELEWLNPHTLQLSTKSLH
HTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIGARPVDLHLKAMQQLGAEIKIEQGYIHAKAPKGLKGNDILF
DKISVTGTENALMAASLAKGITRIINAAKEPEIAQLCAFLQSGGVEIEGVGSSELKIRGVESDALNLKDIQIIPDRIEAG
TYLCVGAITNSQLKINRIIPNHIQAITDKLIEIGFSLDIQENSIEIYPAKKRQAFEITTKEYPGFPTDMQAQFMALATQC
LGTSIIEETLFENRFMHASELQRLGANISLKTNVATISGSTELTGSDVMATDLRASSALVLAALVAKGVSRVHRIYHLDR
GYERLEDKINALGAKVLRLKEK

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=421, Percent_Identity=46.0807600950119, Blast_Score=366, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45786; Mature: 45786

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFLEIVGQVPLKGGVEISGAKNSALPILAATLLSRQEVKIKSLPQVADIKAMALLLQNL
CCHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHC
GAELEWLNPHTLQLSTKSLHHTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIG
CCCEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ARPVDLHLKAMQQLGAEIKIEQGYIHAKAPKGLKGNDILFDKISVTGTENALMAASLAKG
CCCHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHH
ITRIINAAKEPEIAQLCAFLQSGGVEIEGVGSSELKIRGVESDALNLKDIQIIPDRIEAG
HHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCEEEEEECCHHCCC
TYLCVGAITNSQLKINRIIPNHIQAITDKLIEIGFSLDIQENSIEIYPAKKRQAFEITTK
CEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCCCEEEEECC
EYPGFPTDMQAQFMALATQCLGTSIIEETLFENRFMHASELQRLGANISLKTNVATISGS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEEEEECCC
TELTGSDVMATDLRASSALVLAALVAKGVSRVHRIYHLDRGYERLEDKINALGAKVLRLK
CCCCCCCEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EK
CC
>Mature Secondary Structure
MDFLEIVGQVPLKGGVEISGAKNSALPILAATLLSRQEVKIKSLPQVADIKAMALLLQNL
CCHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHC
GAELEWLNPHTLQLSTKSLHHTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIG
CCCEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ARPVDLHLKAMQQLGAEIKIEQGYIHAKAPKGLKGNDILFDKISVTGTENALMAASLAKG
CCCHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHH
ITRIINAAKEPEIAQLCAFLQSGGVEIEGVGSSELKIRGVESDALNLKDIQIIPDRIEAG
HHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCEEEEEECCHHCCC
TYLCVGAITNSQLKINRIIPNHIQAITDKLIEIGFSLDIQENSIEIYPAKKRQAFEITTK
CEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCCCEEEEECC
EYPGFPTDMQAQFMALATQCLGTSIIEETLFENRFMHASELQRLGANISLKTNVATISGS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEEEEECCC
TELTGSDVMATDLRASSALVLAALVAKGVSRVHRIYHLDRGYERLEDKINALGAKVLRLK
CCCCCCCEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA