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The map label for this gene is nifU [H]

Identifier: 108562648

GI number: 108562648

Start: 226924

End: 227904

Strand: Direct

Name: nifU [H]

Synonym: HPAG1_0223

Alternate gene names: 108562648

Gene position: 226924-227904 (Clockwise)

Preceding gene: 108562647

Following gene: 108562649

Centisome position: 14.22

GC content: 44.34

Gene sequence:

>981_bases
ATGGCAAAACATGATTTAGTGGGTTCGGTTCTCTGGGACGCGTATTCTAAAGAAGTTCAAAGGCGCATGGATAACCCCAC
GCATTTAGGGGTCATCACTGAAGAGCAGGCTAAAGCCAAAGACGCTAAGCTCATTGTGGCGGATTATGGCGCAGAGGCAT
GCGGTGATGCGGTGAGGTTGTATTGGCTTGTAGATGAAAGCACGGATAGAATTATTGACGCGAAGTTTAAAAGCTTTGGT
TGCGGAACAGCGATCGCAAGCTCAGACATGATGGTAGAGTTGTGTTTGAATAAAAGAGTCCAAGATGCGGTAAAAATCAC
GAATTTAGATGTGGAAAGAGGCTTGAGAGACGATCCGGACACGCCGGCTGTGCCTGGGCAAAAAATGCACTGCTCGGTGA
TGGCGTATGATGTGATCAAAAAAGCTGCCGGCATGTATTTAGGGAAAAACGCTGAAGATTTTGAAGAAGAAATCATCGTG
TGCGAGTGCGCTAGGGTGAGTTTAGGCACGATTAAAGAAGTGATTAGGCTCAATGATTTAAAAAGCGTTGAAGAAATCAC
TAACTACACCAAAGCCGGCGCTTTTTGTAAAAGCTGTGTGAGGCCTGGAGGGCATGAAAAAAGGGATTATTACTTGGTGG
ATATTCTTAAAGAAGTGCGCGAAGAAATGGAAGCTGAAAAACTTAAAGCGGCCGCTAATAAATCCCAAAATGGGGAATTG
GCTTTCAGGGAAATGACTATGGTTCAAAAGATTAAAGCGGTGGATAAAGTCATTGATGAAAATATCCGCGCTATGCTTAT
GATGGATGGGGGGGATTTAGAGATTTTAGACATTAAAGAAAGCGATGATTACATTGATGTGTATATCCGCTACATGGGGG
CATGCGATGGGTGCATGAGCGCGACTACTGGGACTTTATTTGCCATTGAAAACGCCTTGCAGGAATTATTGGATCGCAGT
ATCAGGGTGTTACCGATTTGA

Upstream 100 bases:

>100_bases
GGAAGCTGAAATTGATAAAACGATTGAAGTTTTCTCTCAAGCGGCTATAAGATTGAGAAACATTTCAAGCTCTTATTAAA
AAGAATATAAAGGAATCAAA

Downstream 100 bases:

>100_bases
TTTGTTTTGAACTTTTTAGGGGGTGGAGGCCTTTTTTGAGCGAAGCGCTAAGAAACTCAAAATGAGGAATGATTAGCACT
TGCAACATTATTCATTATAC

Product: nifU-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MAKHDLVGSVLWDAYSKEVQRRMDNPTHLGVITEEQAKAKDAKLIVADYGAEACGDAVRLYWLVDESTDRIIDAKFKSFG
CGTAIASSDMMVELCLNKRVQDAVKITNLDVERGLRDDPDTPAVPGQKMHCSVMAYDVIKKAAGMYLGKNAEDFEEEIIV
CECARVSLGTIKEVIRLNDLKSVEEITNYTKAGAFCKSCVRPGGHEKRDYYLVDILKEVREEMEAEKLKAAANKSQNGEL
AFREMTMVQKIKAVDKVIDENIRAMLMMDGGDLEILDIKESDDYIDVYIRYMGACDGCMSATTGTLFAIENALQELLDRS
IRVLPI

Sequences:

>Translated_326_residues
MAKHDLVGSVLWDAYSKEVQRRMDNPTHLGVITEEQAKAKDAKLIVADYGAEACGDAVRLYWLVDESTDRIIDAKFKSFG
CGTAIASSDMMVELCLNKRVQDAVKITNLDVERGLRDDPDTPAVPGQKMHCSVMAYDVIKKAAGMYLGKNAEDFEEEIIV
CECARVSLGTIKEVIRLNDLKSVEEITNYTKAGAFCKSCVRPGGHEKRDYYLVDILKEVREEMEAEKLKAAANKSQNGEL
AFREMTMVQKIKAVDKVIDENIRAMLMMDGGDLEILDIKESDDYIDVYIRYMGACDGCMSATTGTLFAIENALQELLDRS
IRVLPI
>Mature_325_residues
AKHDLVGSVLWDAYSKEVQRRMDNPTHLGVITEEQAKAKDAKLIVADYGAEACGDAVRLYWLVDESTDRIIDAKFKSFGC
GTAIASSDMMVELCLNKRVQDAVKITNLDVERGLRDDPDTPAVPGQKMHCSVMAYDVIKKAAGMYLGKNAEDFEEEIIVC
ECARVSLGTIKEVIRLNDLKSVEEITNYTKAGAFCKSCVRPGGHEKRDYYLVDILKEVREEMEAEKLKAAANKSQNGELA
FREMTMVQKIKAVDKVIDENIRAMLMMDGGDLEILDIKESDDYIDVYIRYMGACDGCMSATTGTLFAIENALQELLDRSI
RVLPI

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=132, Percent_Identity=38.6363636363636, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI24307953, Length=131, Percent_Identity=38.1679389312977, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1788878, Length=136, Percent_Identity=35.2941176470588, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17543474, Length=138, Percent_Identity=34.7826086956522, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325122, Length=100, Percent_Identity=46, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324800, Length=141, Percent_Identity=35.4609929078014, Blast_Score=79, Evalue=8e-16,
Organism=Drosophila melanogaster, GI21355597, Length=140, Percent_Identity=38.5714285714286, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007419
- InterPro:   IPR016217
- InterPro:   IPR010238
- InterPro:   IPR001075
- InterPro:   IPR002871
- ProDom:   PD002830 [H]

Pfam domain/function: PF04324 Fer2_BFD; PF01106 NifU; PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 36364; Mature: 36233

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKHDLVGSVLWDAYSKEVQRRMDNPTHLGVITEEQAKAKDAKLIVADYGAEACGDAVRL
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHCCCCCEEEEEECCCHHCCCEEEE
YWLVDESTDRIIDAKFKSFGCGTAIASSDMMVELCLNKRVQDAVKITNLDVERGLRDDPD
EEEEECCCCHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCC
TPAVPGQKMHCSVMAYDVIKKAAGMYLGKNAEDFEEEIIVCECARVSLGTIKEVIRLNDL
CCCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEHHHHCCHHHHHHHHHHHHH
KSVEEITNYTKAGAFCKSCVRPGGHEKRDYYLVDILKEVREEMEAEKLKAAANKSQNGEL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AFREMTMVQKIKAVDKVIDENIRAMLMMDGGDLEILDIKESDDYIDVYIRYMGACDGCMS
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCHHHH
ATTGTLFAIENALQELLDRSIRVLPI
HCCHHHHHHHHHHHHHHHCCCEECCC
>Mature Secondary Structure 
AKHDLVGSVLWDAYSKEVQRRMDNPTHLGVITEEQAKAKDAKLIVADYGAEACGDAVRL
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHCCCCCEEEEEECCCHHCCCEEEE
YWLVDESTDRIIDAKFKSFGCGTAIASSDMMVELCLNKRVQDAVKITNLDVERGLRDDPD
EEEEECCCCHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCC
TPAVPGQKMHCSVMAYDVIKKAAGMYLGKNAEDFEEEIIVCECARVSLGTIKEVIRLNDL
CCCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEHHHHCCHHHHHHHHHHHHH
KSVEEITNYTKAGAFCKSCVRPGGHEKRDYYLVDILKEVREEMEAEKLKAAANKSQNGEL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AFREMTMVQKIKAVDKVIDENIRAMLMMDGGDLEILDIKESDDYIDVYIRYMGACDGCMS
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCHHHH
ATTGTLFAIENALQELLDRSIRVLPI
HCCHHHHHHHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7496536 [H]