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The map label for this gene is aroK [H]

Identifier: 108562580

GI number: 108562580

Start: 161803

End: 162291

Strand: Direct

Name: aroK [H]

Synonym: HPAG1_0155

Alternate gene names: 108562580

Gene position: 161803-162291 (Clockwise)

Preceding gene: 108562579

Following gene: 108562581

Centisome position: 10.14

GC content: 38.85

Gene sequence:

>489_bases
ATGCGGCATTTAGTCTTAATCGGTTTTATGGGGAGCGGTAAAAGCTCTTTAGCGCAAGAATTGGGTCTGGCTTTGAAATT
AGAAGTGTTGGATACGGATATGATCATTAGCGAGAGGGTGGGCTTGAGCGTGAGGGAGATTTTTGAAGAGCTTGGCGAAG
ACAATTTCAGGATGTTTGAAAAAAATTTGATTGATGAATTAAAAACACTCAAAACCCCCCATGTTATTTCTACCGGTGGG
GGGATTATCATGCATGAAAATCTTAAGGGTTTAGGCACAACTTTTTACCTCAAAATGGATTTTGAGACCTTGATTAAGCG
TTTGAATCAAAAAGAAAGGGAGAAACGCCCCCTTTTAAATAATCTCACTCAAGCCAAAGAACTTTTTGAAAAACGCCAAG
CCCTCTATGAAAAAAACGCCTCCTTTATCATTGATGCAAGGGGTGGTTTAAACAATTCTTTAAAACAAGTGCTACAATTC
ATCGCATAA

Upstream 100 bases:

>100_bases
CACAAAGATTATTACCGCATCACGCTCATTTTAGACGGGAAATACCGCTATCTTTTGGAAGAAAAAAACGGGGCGTATGA
ATTAAAATTGAAATAAAAGC

Downstream 100 bases:

>100_bases
ATTTTTTTAAAGGCCTTTTGATGTTGAGTAGAGACATTGTCCAATATTCCAAGATCCGCACCGAGCTATACGCTTATCTT
ACCTATTTGTTTTCGCACAA

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MRHLVLIGFMGSGKSSLAQELGLALKLEVLDTDMIISERVGLSVREIFEELGEDNFRMFEKNLIDELKTLKTPHVISTGG
GIIMHENLKGLGTTFYLKMDFETLIKRLNQKEREKRPLLNNLTQAKELFEKRQALYEKNASFIIDARGGLNNSLKQVLQF
IA

Sequences:

>Translated_162_residues
MRHLVLIGFMGSGKSSLAQELGLALKLEVLDTDMIISERVGLSVREIFEELGEDNFRMFEKNLIDELKTLKTPHVISTGG
GIIMHENLKGLGTTFYLKMDFETLIKRLNQKEREKRPLLNNLTQAKELFEKRQALYEKNASFIIDARGGLNNSLKQVLQF
IA
>Mature_162_residues
MRHLVLIGFMGSGKSSLAQELGLALKLEVLDTDMIISERVGLSVREIFEELGEDNFRMFEKNLIDELKTLKTPHVISTGG
GIIMHENLKGLGTTFYLKMDFETLIKRLNQKEREKRPLLNNLTQAKELFEKRQALYEKNASFIIDARGGLNNSLKQVLQF
IA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=151, Percent_Identity=35.7615894039735, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1786587, Length=168, Percent_Identity=32.1428571428571, Blast_Score=70, Evalue=7e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 18454; Mature: 18454

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHLVLIGFMGSGKSSLAQELGLALKLEVLDTDMIISERVGLSVREIFEELGEDNFRMFE
CCEEEEEEECCCCHHHHHHHHCCEEEEEECCHHHHHHHHCCCHHHHHHHHHCCCHHHHHH
KNLIDELKTLKTPHVISTGGGIIMHENLKGLGTTFYLKMDFETLIKRLNQKEREKRPLLN
HHHHHHHHHHCCCCEEECCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHHHCHHHH
NLTQAKELFEKRQALYEKNASFIIDARGGLNNSLKQVLQFIA
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MRHLVLIGFMGSGKSSLAQELGLALKLEVLDTDMIISERVGLSVREIFEELGEDNFRMFE
CCEEEEEEECCCCHHHHHHHHCCEEEEEECCHHHHHHHHCCCHHHHHHHHHCCCHHHHHH
KNLIDELKTLKTPHVISTGGGIIMHENLKGLGTTFYLKMDFETLIKRLNQKEREKRPLLN
HHHHHHHHHHCCCCEEECCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHHHCHHHH
NLTQAKELFEKRQALYEKNASFIIDARGGLNNSLKQVLQFIA
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA