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The map label for this gene is cynT [H]

Identifier: 108562429

GI number: 108562429

Start: 3244

End: 3909

Strand: Reverse

Name: cynT [H]

Synonym: HPAG1_0004

Alternate gene names: 108562429

Gene position: 3909-3244 (Counterclockwise)

Preceding gene: 108562434

Following gene: 108562428

Centisome position: 0.24

GC content: 39.94

Gene sequence:

>666_bases
GTGGAAGCGTTTTTAGGAGCGTTAGAATTTCAAGAGAATGAATACGAAGAGCTTAAAGAGCTTTATGAGAGCTTAAAAAC
CAAACAAAAGCCCCACACTTTGTTCATTTCTTGCGTGGATTCACGAGTCGTGCCTAATCTAATCACCGGCACCAAACCGG
GCGAATTGTATGTGATCCGCAACATGGGCAATGTGATCCCCCCTAAAACAAGCTATAAAGAGTCCCTTTCTACTATGGCG
AGCATTGAATACGCTATCGTGCATGTGGGCGTTCACAATTTAATTATTTGTGGGCATAGCGATTGTGGGGCTTGCGGGAG
CATTCATTCAATTGATGATGAAACCACCAAAGCTAAAACCCCTTACATTGCAGACTGGATACAATTCTTAGAGCCTATTA
AAGAAGAGTTAAAAAACCACCCGCAATTCAGCAACCATTCCGCCAAGCGTTCATGGCTTACAGAGCGTTTGAATGCACGC
TTGCAACTCAACAACCTCTTAAGCTATGATTTCATTCAAGAAAGAGTGATGGATAACGAATTAAAAATTTTTGGTTGGCA
CTATATCATAGAAACAGGCAGGATTTATAATTATAATTTTGAAAGCCATTTTTTTGAGCCGATTGAAGAAACCATTAAAC
AAAGGAAAAGTCATGAAAACTTCTAA

Upstream 100 bases:

>100_bases
TAACGCCATTATAACAAAAAGAAATGCAAGATTTTTAGCTATGATAAGCGTTTTAAAAACAAAACGAATTTTAATCAAAA
TAAGATTTAAGGGTTAAAGA

Downstream 100 bases:

>100_bases
AACAAAACCCCCCAAATCCGTTTTAATCGCCGGGCCATGCGTCATTGAGAGCTTAGAAAATTTAAGAAGTATCGCTATTA
AATTGCAACCCCTAGCCAAC

Product: beta-carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MEAFLGALEFQENEYEELKELYESLKTKQKPHTLFISCVDSRVVPNLITGTKPGELYVIRNMGNVIPPKTSYKESLSTMA
SIEYAIVHVGVHNLIICGHSDCGACGSIHSIDDETTKAKTPYIADWIQFLEPIKEELKNHPQFSNHSAKRSWLTERLNAR
LQLNNLLSYDFIQERVMDNELKIFGWHYIIETGRIYNYNFESHFFEPIEETIKQRKSHENF

Sequences:

>Translated_221_residues
MEAFLGALEFQENEYEELKELYESLKTKQKPHTLFISCVDSRVVPNLITGTKPGELYVIRNMGNVIPPKTSYKESLSTMA
SIEYAIVHVGVHNLIICGHSDCGACGSIHSIDDETTKAKTPYIADWIQFLEPIKEELKNHPQFSNHSAKRSWLTERLNAR
LQLNNLLSYDFIQERVMDNELKIFGWHYIIETGRIYNYNFESHFFEPIEETIKQRKSHENF
>Mature_221_residues
MEAFLGALEFQENEYEELKELYESLKTKQKPHTLFISCVDSRVVPNLITGTKPGELYVIRNMGNVIPPKTSYKESLSTMA
SIEYAIVHVGVHNLIICGHSDCGACGSIHSIDDETTKAKTPYIADWIQFLEPIKEELKNHPQFSNHSAKRSWLTERLNAR
LQLNNLLSYDFIQERVMDNELKIFGWHYIIETGRIYNYNFESHFFEPIEETIKQRKSHENF

Specific function: Reversible Hydration Of Carbon Dioxide. Carbon Dioxide Formed In The Bicarbonate-Dependent Decomposition Of Cyanate By Cyanase (Cyns) Diffuses Out Of The Cell Faster Than It Would Be Hydrated To Bicarbonate, So The Apparent Function Of This Enzyme Is To C

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=206, Percent_Identity=34.4660194174757, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786318, Length=210, Percent_Identity=27.6190476190476, Blast_Score=73, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25147564, Length=234, Percent_Identity=24.3589743589744, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI115532990, Length=242, Percent_Identity=24.7933884297521, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324292, Length=169, Percent_Identity=30.1775147928994, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24645213, Length=250, Percent_Identity=25.2, Blast_Score=98, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 25703; Mature: 25703

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAFLGALEFQENEYEELKELYESLKTKQKPHTLFISCVDSRVVPNLITGTKPGELYVIR
CCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHCCHHHCCCCCCCEEEEC
NMGNVIPPKTSYKESLSTMASIEYAIVHVGVHNLIICGHSDCGACGSIHSIDDETTKAKT
CCCCCCCCCCHHHHHHHHHHHHHHHHEEECHHEEEEECCCCCCCCCCCCCCCCCCHHCCC
PYIADWIQFLEPIKEELKNHPQFSNHSAKRSWLTERLNARLQLNNLLSYDFIQERVMDNE
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCC
LKIFGWHYIIETGRIYNYNFESHFFEPIEETIKQRKSHENF
EEEEEEEEEEECCEEEEECHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEAFLGALEFQENEYEELKELYESLKTKQKPHTLFISCVDSRVVPNLITGTKPGELYVIR
CCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHCCHHHCCCCCCCEEEEC
NMGNVIPPKTSYKESLSTMASIEYAIVHVGVHNLIICGHSDCGACGSIHSIDDETTKAKT
CCCCCCCCCCHHHHHHHHHHHHHHHHEEECHHEEEEECCCCCCCCCCCCCCCCCCHHCCC
PYIADWIQFLEPIKEELKNHPQFSNHSAKRSWLTERLNARLQLNNLLSYDFIQERVMDNE
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCC
LKIFGWHYIIETGRIYNYNFESHFFEPIEETIKQRKSHENF
EEEEEEEEEEECCEEEEECHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]