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The map label for this gene is ubiH [H]

Identifier: 107021770

GI number: 107021770

Start: 223499

End: 224686

Strand: Reverse

Name: ubiH [H]

Synonym: Bcen_0210

Alternate gene names: 107021770

Gene position: 224686-223499 (Counterclockwise)

Preceding gene: 107021771

Following gene: 107021769

Centisome position: 6.82

GC content: 72.31

Gene sequence:

>1188_bases
ATGACGACCGCTTCCTCCCCGGCCACGCCGGATTACGATCTCGCCATCGTCGGCGCCGGCCCCGTGGGGCTCGCGCTCGC
CGGCTGGCTCGCGCGCCGCAGCGCGACGCGGCACGCATCGATCGCACTGATCGATGCGCGCGAACCGACCGCGAGCGCGA
ACGACCCGCGCGCGATCGCCGTATCGCACGGCAGCCGCGTGCTGCTCGACACGCTCGCATGGCCTGCCGACGCCACGCCG
ATCGAACATATCCACGTGTCGCAGCGCGGCCATTTCGGCCGCACGCTGATCGACCGCGACGAACACGCGCTTGCGGCGCT
CGGCTACGTCGTGCGCTATGGCTCGATCGTGCAGGCGCTCGCGGGCGCCGTGCGCGGCACGCGGGTCGACTGGCTCACGT
CGACCACCGCGCACACGCCGCAGCAGGACGCCGACGGCGTCACGCTGACGCTCGACGGCCCGCAAGGCGGGCGCACGCTG
CGCGCGCGCATCGTCATCAATGCCGAAGGCGGGCTGTTCCACGAACAGCAGGCCGACGCAGGCAAGCATCGCCGCGACTA
CGGTCAGACCGCGCTCGTCGGCACGGTCACGGTCTCGGCGCCGCGCCCGAACGTCGCGTGGGAACGCTTCACGCACGAAG
GCCCGCTCGCGCTGCTGCCGCTCGGCGGCCCGCGCCAGGCCGACTACTCGCTCGTCTGGTGCTGTACGCCCGACGAAGCG
GCGCGACGGGCCGCGCTGCCCGACGACGCATTCCTGCGCGAGCTCGGCAGCGTGTTCGGCGAGCGCATGAGCGAATTCGT
CGCGATCGCCGGGCGCGCGTCGTTCCCGCTCGGCCTGAACGCGGCGCAGACGCTCGTCAGCGGCCGCATCGCGATCGTCG
GCAATGCCGCGCAGACGCTGCACCCGGTTGCGGGCCAGGGGCTCAACCTCGGGCTGCGCGACGCGCACACGCTCGTCGAC
ACGCTGTCCGCACAAGGCTTCGAAGCGACCGCGCTCGCGACCTTCAACGCGCGCCGCGCGCTTGACCGGCGCCTCACGAT
CGGCGCGACCGACACGCTCGCGCGCCTGTTTACGATCGACGCGGGCCCGCTTCCGCTGCTGCGCGGCGCGGCGCTCACCG
CGCTCGAATTCGTGCCGCCGCTTAAAAAGGTGATCGCGCGCCAGATGATGTTCGGCCAGCGCAACTGA

Upstream 100 bases:

>100_bases
ATCACGCGCGGCGTGCCGGTCGCGGCCGACGAGATCGAGGCGCTGATGCGCGCGGACGCATGACCGGGCGCCGACCGTTA
CCTCCGTTTCACGAATCAAG

Downstream 100 bases:

>100_bases
CACGCGGCGCACCGCACGGCCTCTTCGGGCAAACCAGGCAAACCGGGTCAAATCGGCGGGGCGTGGGAATACGGTAAAAT
GCCCGTTTTCCGTCTTCCCT

Product: hypothetical protein

Products: H2O; 2-octaprenyl-6-methoxy-1,4-benzoquinone [C]

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MTTASSPATPDYDLAIVGAGPVGLALAGWLARRSATRHASIALIDAREPTASANDPRAIAVSHGSRVLLDTLAWPADATP
IEHIHVSQRGHFGRTLIDRDEHALAALGYVVRYGSIVQALAGAVRGTRVDWLTSTTAHTPQQDADGVTLTLDGPQGGRTL
RARIVINAEGGLFHEQQADAGKHRRDYGQTALVGTVTVSAPRPNVAWERFTHEGPLALLPLGGPRQADYSLVWCCTPDEA
ARRAALPDDAFLRELGSVFGERMSEFVAIAGRASFPLGLNAAQTLVSGRIAIVGNAAQTLHPVAGQGLNLGLRDAHTLVD
TLSAQGFEATALATFNARRALDRRLTIGATDTLARLFTIDAGPLPLLRGAALTALEFVPPLKKVIARQMMFGQRN

Sequences:

>Translated_395_residues
MTTASSPATPDYDLAIVGAGPVGLALAGWLARRSATRHASIALIDAREPTASANDPRAIAVSHGSRVLLDTLAWPADATP
IEHIHVSQRGHFGRTLIDRDEHALAALGYVVRYGSIVQALAGAVRGTRVDWLTSTTAHTPQQDADGVTLTLDGPQGGRTL
RARIVINAEGGLFHEQQADAGKHRRDYGQTALVGTVTVSAPRPNVAWERFTHEGPLALLPLGGPRQADYSLVWCCTPDEA
ARRAALPDDAFLRELGSVFGERMSEFVAIAGRASFPLGLNAAQTLVSGRIAIVGNAAQTLHPVAGQGLNLGLRDAHTLVD
TLSAQGFEATALATFNARRALDRRLTIGATDTLARLFTIDAGPLPLLRGAALTALEFVPPLKKVIARQMMFGQRN
>Mature_394_residues
TTASSPATPDYDLAIVGAGPVGLALAGWLARRSATRHASIALIDAREPTASANDPRAIAVSHGSRVLLDTLAWPADATPI
EHIHVSQRGHFGRTLIDRDEHALAALGYVVRYGSIVQALAGAVRGTRVDWLTSTTAHTPQQDADGVTLTLDGPQGGRTLR
ARIVINAEGGLFHEQQADAGKHRRDYGQTALVGTVTVSAPRPNVAWERFTHEGPLALLPLGGPRQADYSLVWCCTPDEAA
RRAALPDDAFLRELGSVFGERMSEFVAIAGRASFPLGLNAAQTLVSGRIAIVGNAAQTLHPVAGQGLNLGLRDAHTLVDT
LSAQGFEATALATFNARRALDRRLTIGATDTLARLFTIDAGPLPLLRGAALTALEFVPPLKKVIARQMMFGQRN

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=408, Percent_Identity=29.656862745098, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI32967307, Length=350, Percent_Identity=30.8571428571429, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1789274, Length=400, Percent_Identity=35.25, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1789273, Length=397, Percent_Identity=31.7380352644836, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786883, Length=389, Percent_Identity=31.1053984575836, Blast_Score=113, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321694, Length=468, Percent_Identity=22.8632478632479, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI19920760, Length=444, Percent_Identity=26.8018018018018, Blast_Score=105, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.- [C]

Molecular weight: Translated: 41855; Mature: 41724

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTASSPATPDYDLAIVGAGPVGLALAGWLARRSATRHASIALIDAREPTASANDPRAIA
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCEEE
VSHGSRVLLDTLAWPADATPIEHIHVSQRGHFGRTLIDRDEHALAALGYVVRYGSIVQAL
EECCCEEEEHHHCCCCCCCCHHEEEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
AGAVRGTRVDWLTSTTAHTPQQDADGVTLTLDGPQGGRTLRARIVINAEGGLFHEQQADA
HHHHCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHC
GKHRRDYGQTALVGTVTVSAPRPNVAWERFTHEGPLALLPLGGPRQADYSLVWCCTPDEA
HHHHHHCCCEEEEEEEEEECCCCCCHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCHHH
ARRAALPDDAFLRELGSVFGERMSEFVAIAGRASFPLGLNAAQTLVSGRIAIVGNAAQTL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCHHHH
HPVAGQGLNLGLRDAHTLVDTLSAQGFEATALATFNARRALDRRLTIGATDTLARLFTID
CHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCEEEECCHHHHHHHEEEC
AGPLPLLRGAALTALEFVPPLKKVIARQMMFGQRN
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTASSPATPDYDLAIVGAGPVGLALAGWLARRSATRHASIALIDAREPTASANDPRAIA
CCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCEEE
VSHGSRVLLDTLAWPADATPIEHIHVSQRGHFGRTLIDRDEHALAALGYVVRYGSIVQAL
EECCCEEEEHHHCCCCCCCCHHEEEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
AGAVRGTRVDWLTSTTAHTPQQDADGVTLTLDGPQGGRTLRARIVINAEGGLFHEQQADA
HHHHCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHC
GKHRRDYGQTALVGTVTVSAPRPNVAWERFTHEGPLALLPLGGPRQADYSLVWCCTPDEA
HHHHHHCCCEEEEEEEEEECCCCCCHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCHHH
ARRAALPDDAFLRELGSVFGERMSEFVAIAGRASFPLGLNAAQTLVSGRIAIVGNAAQTL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCHHHH
HPVAGQGLNLGLRDAHTLVDTLSAQGFEATALATFNARRALDRRLTIGATDTLARLFTID
CHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCEEEECCHHHHHHHEEEC
AGPLPLLRGAALTALEFVPPLKKVIARQMMFGQRN
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-octaprenyl-6-methoxyphenol; O2 [C]

Specific reaction: 2-octaprenyl-6-methoxyphenol + O2 = H2O + 2-octaprenyl-6-methoxy-1,4-benzoquinone [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]