| Definition | Sphingopyxis alaskensis RB2256, complete genome. |
|---|---|
| Accession | NC_008048 |
| Length | 3,345,170 |
Click here to switch to the map view.
The map label for this gene is fabG [H]
Identifier: 103488547
GI number: 103488547
Start: 3221199
End: 3221975
Strand: Reverse
Name: fabG [H]
Synonym: Sala_3071
Alternate gene names: 103488547
Gene position: 3221975-3221199 (Counterclockwise)
Preceding gene: 103488548
Following gene: 103488546
Centisome position: 96.32
GC content: 63.96
Gene sequence:
>777_bases ATGAGCCTGTTCGACATGACCGGCCAGGTCGCGCTGATCACCGGATCGTCGCGCGGCATCGGCAAGGCGACGGCGGAAGC GATGGCCGAACAGGGCGCGAAGGTCGTGATTTCGAGCCGCAAGCAAGATGCGTGCGACGCCACCGCGGCGGAGATCAACG CGCGGTTCGGCGAAGGCACCGCGATTGCGGTCGCGGCGAACATCTCGTCGAAGGATGATCTTCAGAACCTCGTCAACGAG ACGCGCGCCGCCTTCGGCAAGATCACCGCGCTCGTCTGCAACGCCGCGTCGAACCCCTATTATGGCCCCGGCCTCGGCAT CAGCGACGAGCAGTTCCGCAAGATCATGGACAATAATATCCTGTCCAACCACTGGCTGATCAGCATGGTCGCGCCCGAAA TGCTCGAACGCGGCGACGGGTCGATCACGATCATCAGTTCGATCGGCGGGCTGAAAGGATCGCCGATCATCGGCGCTTAC GGGATTTCCAAGGCCGCCGACATGCAGGTCGCGCGCAATTTTTCGGTCGAGTTCGGGCCGAGGGGCGTGCGCGTCAATTG CATCGCGCCGGGGCTGATCCGTACCGACATGGCGCGCGCCTTGTGGGAAAATCCCGAAAATCTCAAACGCTCGACCGCCG CCTCGACGCTGAAGCGCATCGGCGAACCGCACGAGATCGCGGGCGCCGCGGTGTTCCTCGCCAGCAAGGCGGGGGCTTTT ACCACCGGCCAGACCATCGTTTGCGATGGCGGGGCCACGATTTCGGGAGGCGCATGA
Upstream 100 bases:
>100_bases TCATCGACGGCACCGCCTCGTCGGCTCATGCCAAGGCGATGTCGGAGCGCGTGCAGCCGCTGGCCGCACGCGCGTGGGAC TTTGCACGAAAGGCCGGGGC
Downstream 100 bases:
>100_bases TGGGCGCGTTGGACGGCAAGGTTGCGATCATCACGGGCGCGGGCAGCGGCATCGGCCGCGCGAGCGCGCTGCGGTTTGCT GCCGAAGGGGCGAAGCTCGT
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 258; Mature: 257
Protein sequence:
>258_residues MSLFDMTGQVALITGSSRGIGKATAEAMAEQGAKVVISSRKQDACDATAAEINARFGEGTAIAVAANISSKDDLQNLVNE TRAAFGKITALVCNAASNPYYGPGLGISDEQFRKIMDNNILSNHWLISMVAPEMLERGDGSITIISSIGGLKGSPIIGAY GISKAADMQVARNFSVEFGPRGVRVNCIAPGLIRTDMARALWENPENLKRSTAASTLKRIGEPHEIAGAAVFLASKAGAF TTGQTIVCDGGATISGGA
Sequences:
>Translated_258_residues MSLFDMTGQVALITGSSRGIGKATAEAMAEQGAKVVISSRKQDACDATAAEINARFGEGTAIAVAANISSKDDLQNLVNE TRAAFGKITALVCNAASNPYYGPGLGISDEQFRKIMDNNILSNHWLISMVAPEMLERGDGSITIISSIGGLKGSPIIGAY GISKAADMQVARNFSVEFGPRGVRVNCIAPGLIRTDMARALWENPENLKRSTAASTLKRIGEPHEIAGAAVFLASKAGAF TTGQTIVCDGGATISGGA >Mature_257_residues SLFDMTGQVALITGSSRGIGKATAEAMAEQGAKVVISSRKQDACDATAAEINARFGEGTAIAVAANISSKDDLQNLVNET RAAFGKITALVCNAASNPYYGPGLGISDEQFRKIMDNNILSNHWLISMVAPEMLERGDGSITIISSIGGLKGSPIIGAYG ISKAADMQVARNFSVEFGPRGVRVNCIAPGLIRTDMARALWENPENLKRSTAASTLKRIGEPHEIAGAAVFLASKAGAFT TGQTIVCDGGATISGGA
Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=37.246963562753, Blast_Score=177, Evalue=8e-45, Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=34.9397590361446, Blast_Score=152, Evalue=2e-37, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=32, Blast_Score=143, Evalue=2e-34, Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=36.0406091370558, Blast_Score=129, Evalue=2e-30, Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=30.5019305019305, Blast_Score=124, Evalue=8e-29, Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=36.3157894736842, Blast_Score=123, Evalue=1e-28, Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=30.8943089430894, Blast_Score=109, Evalue=2e-24, Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=31.4893617021277, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=30.9236947791165, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI210032110, Length=202, Percent_Identity=28.7128712871287, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI7705855, Length=195, Percent_Identity=31.7948717948718, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=28.740157480315, Blast_Score=88, Evalue=9e-18, Organism=Homo sapiens, GI302344755, Length=109, Percent_Identity=37.6146788990826, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI226371731, Length=197, Percent_Identity=28.4263959390863, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI142976729, Length=256, Percent_Identity=24.609375, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI66933014, Length=258, Percent_Identity=27.5193798449612, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=28.125, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=27.0588235294118, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI4503301, Length=251, Percent_Identity=27.0916334661355, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI302344752, Length=176, Percent_Identity=28.9772727272727, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI223718074, Length=226, Percent_Identity=27.8761061946903, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI209862901, Length=215, Percent_Identity=29.7674418604651, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI19923983, Length=215, Percent_Identity=29.7674418604651, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI32455239, Length=197, Percent_Identity=27.4111675126904, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI5031765, Length=197, Percent_Identity=27.4111675126904, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI109715829, Length=245, Percent_Identity=26.530612244898, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI4557649, Length=201, Percent_Identity=28.8557213930348, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=26.9430051813472, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI31542939, Length=211, Percent_Identity=26.5402843601896, Blast_Score=64, Evalue=9e-11, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=34.9397590361446, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=32.0158102766798, Blast_Score=118, Evalue=3e-28, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=32.8125, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=30.6201550387597, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI1789378, Length=244, Percent_Identity=30.327868852459, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=29.5275590551181, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=28.6821705426357, Blast_Score=88, Evalue=4e-19, Organism=Escherichia coli, GI2367365, Length=251, Percent_Identity=31.4741035856574, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=31.8007662835249, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=28.0487804878049, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=31.0756972111554, Blast_Score=81, Evalue=8e-17, Organism=Escherichia coli, GI1786701, Length=194, Percent_Identity=30.9278350515464, Blast_Score=75, Evalue=6e-15, Organism=Escherichia coli, GI1789057, Length=264, Percent_Identity=23.4848484848485, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787526, Length=207, Percent_Identity=26.5700483091787, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=27.4193548387097, Blast_Score=63, Evalue=1e-11, Organism=Escherichia coli, GI1787545, Length=260, Percent_Identity=24.6153846153846, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=33.3333333333333, Blast_Score=150, Evalue=4e-37, Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=34.8178137651822, Blast_Score=149, Evalue=2e-36, Organism=Caenorhabditis elegans, GI17562906, Length=274, Percent_Identity=32.8467153284672, Blast_Score=116, Evalue=9e-27, Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=34.6007604562738, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=33.0798479087452, Blast_Score=114, Evalue=4e-26, Organism=Caenorhabditis elegans, GI17560220, Length=272, Percent_Identity=32.7205882352941, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=32.824427480916, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=33.2046332046332, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=31.5789473684211, Blast_Score=110, Evalue=6e-25, Organism=Caenorhabditis elegans, GI17560332, Length=279, Percent_Identity=32.6164874551971, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=32.4, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=31.5789473684211, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=33.2075471698113, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=27.6515151515151, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=28.4644194756554, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=32.5757575757576, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=32.1969696969697, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=30.1587301587302, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=30.1115241635688, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=30.0751879699248, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=29.1497975708502, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=31.8181818181818, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17544670, Length=276, Percent_Identity=28.9855072463768, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=30.1158301158301, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI71997099, Length=234, Percent_Identity=31.1965811965812, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=26.2948207171315, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17555612, Length=273, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=24.4979919678715, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=27.6422764227642, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17538182, Length=263, Percent_Identity=28.1368821292776, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=26.4822134387352, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17567345, Length=194, Percent_Identity=30.9278350515464, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17561272, Length=253, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=30.7392996108949, Blast_Score=109, Evalue=4e-25, Organism=Saccharomyces cerevisiae, GI6322227, Length=232, Percent_Identity=27.1551724137931, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6322226, Length=197, Percent_Identity=29.9492385786802, Blast_Score=69, Evalue=8e-13, Organism=Saccharomyces cerevisiae, GI6319635, Length=255, Percent_Identity=25.0980392156863, Blast_Score=67, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6323882, Length=251, Percent_Identity=23.1075697211155, Blast_Score=62, Evalue=9e-11, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=37.5, Blast_Score=167, Evalue=6e-42, Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=37.246963562753, Blast_Score=140, Evalue=6e-34, Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=34.8178137651822, Blast_Score=126, Evalue=2e-29, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=32.9365079365079, Blast_Score=123, Evalue=1e-28, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=32.2834645669291, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI24644337, Length=258, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI24639444, Length=254, Percent_Identity=31.1023622047244, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI24640492, Length=240, Percent_Identity=27.5, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24640442, Length=219, Percent_Identity=27.3972602739726, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=26.0869565217391, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI281364892, Length=225, Percent_Identity=28, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=27.5193798449612, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=24.7474747474747, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=25.6410256410256, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24580925, Length=270, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=5e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26739; Mature: 26608
Theoretical pI: Translated: 7.30; Mature: 7.30
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 4.7 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLFDMTGQVALITGSSRGIGKATAEAMAEQGAKVVISSRKQDACDATAAEINARFGEGT CCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCE AIAVAANISSKDDLQNLVNETRAAFGKITALVCNAASNPYYGPGLGISDEQFRKIMDNNI EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHCCC LSNHWLISMVAPEMLERGDGSITIISSIGGLKGSPIIGAYGISKAADMQVARNFSVEFGP CCCCEEEEHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECCCCCHHHHHHHHCCCEEECC RGVRVNCIAPGLIRTDMARALWENPENLKRSTAASTLKRIGEPHEIAGAAVFLASKAGAF CCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHEEEEECCCCCC TTGQTIVCDGGATISGGA CCCCEEEECCCCCCCCCC >Mature Secondary Structure SLFDMTGQVALITGSSRGIGKATAEAMAEQGAKVVISSRKQDACDATAAEINARFGEGT CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCE AIAVAANISSKDDLQNLVNETRAAFGKITALVCNAASNPYYGPGLGISDEQFRKIMDNNI EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHCCC LSNHWLISMVAPEMLERGDGSITIISSIGGLKGSPIIGAYGISKAADMQVARNFSVEFGP CCCCEEEEHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECCCCCHHHHHHHHCCCEEECC RGVRVNCIAPGLIRTDMARALWENPENLKRSTAASTLKRIGEPHEIAGAAVFLASKAGAF CCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHEEEEECCCCCC TTGQTIVCDGGATISGGA CCCCEEEECCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10684935 [H]