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The map label for this gene is ptrB [H]

Identifier: 103488472

GI number: 103488472

Start: 3136497

End: 3138644

Strand: Direct

Name: ptrB [H]

Synonym: Sala_2995

Alternate gene names: 103488472

Gene position: 3136497-3138644 (Clockwise)

Preceding gene: 103488466

Following gene: 103488473

Centisome position: 93.76

GC content: 61.5

Gene sequence:

>2148_bases
ATGTTTCTGGCCGCAATTACCACCCCGCTTGTCGTGCCCGCCAGCGCCCCTGCCCAACAGAAAGAGAGTGAATTGACCGA
CCGCCCCGCGCTGCCCGCCGCTCCCGTTGCCGAGCAGCGGCCCCACACCGTCACGCTCCACGGCAAGACGCTGTCCGATC
CATGGTTCTGGCTGCGCGACCCAGGCTATCCGACGATCGATGATGCCGACATCCTCGACTATGTGAAGGCCGAAAATGCC
TATTTCGACGCGGCGATGAAACCGCATGCCGATCTGGTCGAAACGCTGTTTCAGGAGATGAAGGGACGCATCAAGGAGGC
CGACAGCTCGGTCCCGCAAAAGGACGGCGACTGGCTTTACTGGGTCGAATATGAAGAGGGCGCCGAATATAAGAAATGGT
ATCGCAAGCCGGTGGCCGGGGGCGAAACCCAGCTGATCCTCGACGAGGTCGCGATGTCCGACGGCAAGGATTATTTCCGC
CTCGCCGAAGTTTCGGTCAGCCCCGACGGCAAGCTGATGGCCTTTTCGTTCGACGACAATGGTTCGGAACGGTTCGAGGC
GCGCATCCGCAATCTCGAAACCGGCGAACTGCTGCCCGATGTCATCCCCGGCACCTTGTCGTCGCTCGTCTGGACCGCGA
ACAATGACGCGATCCTCTATGGCCTCGCGAACGAGAATTGGCGCACCGACAATGTCCGGCTGCACAAGCTCGGCACGCCG
GTCGCGCAAGATAAATTGCTCTACAAGGAGGCCGACATCGGCTTCGGCGTCGGCATCGGCAAGACGGCGGCCGACAATTA
TATCGTCATCGCGACGGGCGATAACGAGACGAGCGAGGTCTATCTGCTTCCCGCCGACAATCCCGAAGCGCCGATGCAGC
TCGTCTCGCCGCGCCGGAAGGGCCGCGAATACAGCGTCGATGAGCGCGAGGGCATTCTCTATATCCACACCAACGACGAG
CACCCCAATTTCCGCATTGCGACCGCGAGCATCGACAAGCCCGGCGAATGGACGACGCTGATCCCCGGCTCGGACCACAG
CTACATCACCGGCCTGTCGATCTTTCGCGACTATTTCGTGCTGGAAGCGCGCGAGGACGGCCTCGATCAGGTCGATGTGC
GCCGGTATGACGCGCCGCTGACCCCCGGCCGGATCCGGTTTCCCGAGGCAACCTATGTGGCGGGGCTTGGCGACAATCCC
GAATATCATCAGGACAAGCTCCGGCTCGACTATGAATCGATGGTCACGCCCGACACCGTCTATGACTATGACGTGGCGAG
TGGAACGCTCGAAACGCTGAAGGTACAAGAAATCCCTTCTGGCTATGATTCTCAACAATATATTACCGAATGGGTTAGTT
TGCCGAGTCGTGACGGCAAGACGATGATCCCCGCCTCGCTCGTCTACAAAAAGGGGACGAAGCTCGACGGCAGCGCGCCG
ATGCACCTCTATGCCTATGGCTCCTACGGCTACCGCGTCCCGCCCGGCTTTTCGACGACGCGGCTCAGCCTCGTCGATCG
CGGGATGATCTATGCCATCGCGCATGTCCGGGGCGGCGACGACATGGGGCGCGCCTGGTATCTCGCGGGCAAGACGACCG
AGCGCACCAACACGTTCAACGACTTCATCGACGTCGCAAAGGGCCTGATCGCAAAAAAATACACCAGCGCAGGCAAGATT
TCGATCGAGGGCCGCTCGGCGGGCGGGCAGGTGATGGGGGTCGTCTATAATCAGGCGCCCGAACTGTGGGGCGCGGTGCT
TGCCGGCGTGCCCTTCGTCGATGTCATCAACACGATGATCGACGAAAGCTTGCCGCTCACCCCCGGCGAATGGCCCGAAT
GGGGCAATCCGATCACCGACAAGGCCGCCTTCGACTATATGCTGAGCTACAGCCCTTATGACAATGTGGCGGCCAAGGCC
TATCCGCCCATGCTCGTGTCGGCGGGGCTCAACGACCCGCGCGTGACCTATTGGGAACCCGCCAAATGGGTCGCGAAGCT
GCGCGCGACGCGCACCAATGATTCGCTGCTGCTGCTGCGCACCAACATGGGCGCGGGTCATGCGGGCAAATCGGGCCGCT
GGGGCGCGCTGCGCGAGGATGCCGAGGAATATGCCTTCGTGCTGACGCAACTGGGGGTGGAGAAATAG

Upstream 100 bases:

>100_bases
GTGGACGGGGCTGGACATGGTCGCTTCCTTGTTCCTACATCGCAGCCGTTCCGGCCCATGCGGGCGATGCTGCGGGAGTT
GTCTTGTGCGCGCTATTTGG

Downstream 100 bases:

>100_bases
GACCGCGCACCATCACTTCGCGACAGGATTGCGACATATCGGCAAATCGCTGCGACATCGCCGACCGATATCTCCCCGCG
ACAAGGGAGGGACCGGATGT

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 715; Mature: 715

Protein sequence:

>715_residues
MFLAAITTPLVVPASAPAQQKESELTDRPALPAAPVAEQRPHTVTLHGKTLSDPWFWLRDPGYPTIDDADILDYVKAENA
YFDAAMKPHADLVETLFQEMKGRIKEADSSVPQKDGDWLYWVEYEEGAEYKKWYRKPVAGGETQLILDEVAMSDGKDYFR
LAEVSVSPDGKLMAFSFDDNGSERFEARIRNLETGELLPDVIPGTLSSLVWTANNDAILYGLANENWRTDNVRLHKLGTP
VAQDKLLYKEADIGFGVGIGKTAADNYIVIATGDNETSEVYLLPADNPEAPMQLVSPRRKGREYSVDEREGILYIHTNDE
HPNFRIATASIDKPGEWTTLIPGSDHSYITGLSIFRDYFVLEAREDGLDQVDVRRYDAPLTPGRIRFPEATYVAGLGDNP
EYHQDKLRLDYESMVTPDTVYDYDVASGTLETLKVQEIPSGYDSQQYITEWVSLPSRDGKTMIPASLVYKKGTKLDGSAP
MHLYAYGSYGYRVPPGFSTTRLSLVDRGMIYAIAHVRGGDDMGRAWYLAGKTTERTNTFNDFIDVAKGLIAKKYTSAGKI
SIEGRSAGGQVMGVVYNQAPELWGAVLAGVPFVDVINTMIDESLPLTPGEWPEWGNPITDKAAFDYMLSYSPYDNVAAKA
YPPMLVSAGLNDPRVTYWEPAKWVAKLRATRTNDSLLLLRTNMGAGHAGKSGRWGALREDAEEYAFVLTQLGVEK

Sequences:

>Translated_715_residues
MFLAAITTPLVVPASAPAQQKESELTDRPALPAAPVAEQRPHTVTLHGKTLSDPWFWLRDPGYPTIDDADILDYVKAENA
YFDAAMKPHADLVETLFQEMKGRIKEADSSVPQKDGDWLYWVEYEEGAEYKKWYRKPVAGGETQLILDEVAMSDGKDYFR
LAEVSVSPDGKLMAFSFDDNGSERFEARIRNLETGELLPDVIPGTLSSLVWTANNDAILYGLANENWRTDNVRLHKLGTP
VAQDKLLYKEADIGFGVGIGKTAADNYIVIATGDNETSEVYLLPADNPEAPMQLVSPRRKGREYSVDEREGILYIHTNDE
HPNFRIATASIDKPGEWTTLIPGSDHSYITGLSIFRDYFVLEAREDGLDQVDVRRYDAPLTPGRIRFPEATYVAGLGDNP
EYHQDKLRLDYESMVTPDTVYDYDVASGTLETLKVQEIPSGYDSQQYITEWVSLPSRDGKTMIPASLVYKKGTKLDGSAP
MHLYAYGSYGYRVPPGFSTTRLSLVDRGMIYAIAHVRGGDDMGRAWYLAGKTTERTNTFNDFIDVAKGLIAKKYTSAGKI
SIEGRSAGGQVMGVVYNQAPELWGAVLAGVPFVDVINTMIDESLPLTPGEWPEWGNPITDKAAFDYMLSYSPYDNVAAKA
YPPMLVSAGLNDPRVTYWEPAKWVAKLRATRTNDSLLLLRTNMGAGHAGKSGRWGALREDAEEYAFVLTQLGVEK
>Mature_715_residues
MFLAAITTPLVVPASAPAQQKESELTDRPALPAAPVAEQRPHTVTLHGKTLSDPWFWLRDPGYPTIDDADILDYVKAENA
YFDAAMKPHADLVETLFQEMKGRIKEADSSVPQKDGDWLYWVEYEEGAEYKKWYRKPVAGGETQLILDEVAMSDGKDYFR
LAEVSVSPDGKLMAFSFDDNGSERFEARIRNLETGELLPDVIPGTLSSLVWTANNDAILYGLANENWRTDNVRLHKLGTP
VAQDKLLYKEADIGFGVGIGKTAADNYIVIATGDNETSEVYLLPADNPEAPMQLVSPRRKGREYSVDEREGILYIHTNDE
HPNFRIATASIDKPGEWTTLIPGSDHSYITGLSIFRDYFVLEAREDGLDQVDVRRYDAPLTPGRIRFPEATYVAGLGDNP
EYHQDKLRLDYESMVTPDTVYDYDVASGTLETLKVQEIPSGYDSQQYITEWVSLPSRDGKTMIPASLVYKKGTKLDGSAP
MHLYAYGSYGYRVPPGFSTTRLSLVDRGMIYAIAHVRGGDDMGRAWYLAGKTTERTNTFNDFIDVAKGLIAKKYTSAGKI
SIEGRSAGGQVMGVVYNQAPELWGAVLAGVPFVDVINTMIDESLPLTPGEWPEWGNPITDKAAFDYMLSYSPYDNVAAKA
YPPMLVSAGLNDPRVTYWEPAKWVAKLRATRTNDSLLLLRTNMGAGHAGKSGRWGALREDAEEYAFVLTQLGVEK

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=706, Percent_Identity=25.3541076487252, Blast_Score=193, Evalue=6e-49,
Organism=Homo sapiens, GI284172438, Length=512, Percent_Identity=28.515625, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI284172431, Length=512, Percent_Identity=28.515625, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI284172420, Length=512, Percent_Identity=28.3203125, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI284172413, Length=512, Percent_Identity=28.3203125, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI70778815, Length=512, Percent_Identity=28.3203125, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI108860686, Length=256, Percent_Identity=33.984375, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI108860692, Length=212, Percent_Identity=35.377358490566, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI1788150, Length=685, Percent_Identity=39.7080291970803, Blast_Score=484, Evalue=1e-137,
Organism=Drosophila melanogaster, GI221510989, Length=701, Percent_Identity=25.6776034236805, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24583414, Length=771, Percent_Identity=23.3463035019455, Blast_Score=173, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 79428; Mature: 79428

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLAAITTPLVVPASAPAQQKESELTDRPALPAAPVAEQRPHTVTLHGKTLSDPWFWLRD
CEEEEECCCEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEC
PGYPTIDDADILDYVKAENAYFDAAMKPHADLVETLFQEMKGRIKEADSSVPQKDGDWLY
CCCCCCCCHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
WVEYEEGAEYKKWYRKPVAGGETQLILDEVAMSDGKDYFRLAEVSVSPDGKLMAFSFDDN
EEEECCCCHHHHHHHCCCCCCCCEEEEEHHHHCCCCCEEEEEEEEECCCCCEEEEEECCC
GSERFEARIRNLETGELLPDVIPGTLSSLVWTANNDAILYGLANENWRTDNVRLHKLGTP
CHHHHHHHHHCCCCCCCCHHHCCCCHHHEEEECCCCEEEEEECCCCCCCCCEEEEECCCC
VAQDKLLYKEADIGFGVGIGKTAADNYIVIATGDNETSEVYLLPADNPEAPMQLVSPRRK
HHHHHHEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHCHHHC
GREYSVDEREGILYIHTNDEHPNFRIATASIDKPGEWTTLIPGSDHSYITGLSIFRDYFV
CCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCEEHHHHHHHHHEE
LEAREDGLDQVDVRRYDAPLTPGRIRFPEATYVAGLGDNPEYHQDKLRLDYESMVTPDTV
EEECCCCCCCCCHHHCCCCCCCCEEECCCCEEEEECCCCCCCCCHHHEECHHHHCCCCCE
YDYDVASGTLETLKVQEIPSGYDSQQYITEWVSLPSRDGKTMIPASLVYKKGTKLDGSAP
EECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCEECCHHHHEECCCCCCCCCC
MHLYAYGSYGYRVPPGFSTTRLSLVDRGMIYAIAHVRGGDDMGRAWYLAGKTTERTNTFN
EEEEEECCCCCCCCCCCCCEEHHHHHCCEEEEEEEECCCCCCCCEEEEECCCCCCCCHHH
DFIDVAKGLIAKKYTSAGKISIEGRSAGGQVMGVVYNQAPELWGAVLAGVPFVDVINTMI
HHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHCCCHHHHHHHHH
DESLPLTPGEWPEWGNPITDKAAFDYMLSYSPYDNVAAKAYPPMLVSAGLNDPRVTYWEP
HCCCCCCCCCCCCCCCCCCCHHHHHHHEECCCCCCCCHHCCCCEEEECCCCCCCEEEECH
AKWVAKLRATRTNDSLLLLRTNMGAGHAGKSGRWGALREDAEEYAFVLTQLGVEK
HHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFLAAITTPLVVPASAPAQQKESELTDRPALPAAPVAEQRPHTVTLHGKTLSDPWFWLRD
CEEEEECCCEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEC
PGYPTIDDADILDYVKAENAYFDAAMKPHADLVETLFQEMKGRIKEADSSVPQKDGDWLY
CCCCCCCCHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
WVEYEEGAEYKKWYRKPVAGGETQLILDEVAMSDGKDYFRLAEVSVSPDGKLMAFSFDDN
EEEECCCCHHHHHHHCCCCCCCCEEEEEHHHHCCCCCEEEEEEEEECCCCCEEEEEECCC
GSERFEARIRNLETGELLPDVIPGTLSSLVWTANNDAILYGLANENWRTDNVRLHKLGTP
CHHHHHHHHHCCCCCCCCHHHCCCCHHHEEEECCCCEEEEEECCCCCCCCCEEEEECCCC
VAQDKLLYKEADIGFGVGIGKTAADNYIVIATGDNETSEVYLLPADNPEAPMQLVSPRRK
HHHHHHEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHCHHHC
GREYSVDEREGILYIHTNDEHPNFRIATASIDKPGEWTTLIPGSDHSYITGLSIFRDYFV
CCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCEEHHHHHHHHHEE
LEAREDGLDQVDVRRYDAPLTPGRIRFPEATYVAGLGDNPEYHQDKLRLDYESMVTPDTV
EEECCCCCCCCCHHHCCCCCCCCEEECCCCEEEEECCCCCCCCCHHHEECHHHHCCCCCE
YDYDVASGTLETLKVQEIPSGYDSQQYITEWVSLPSRDGKTMIPASLVYKKGTKLDGSAP
EECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCEECCHHHHEECCCCCCCCCC
MHLYAYGSYGYRVPPGFSTTRLSLVDRGMIYAIAHVRGGDDMGRAWYLAGKTTERTNTFN
EEEEEECCCCCCCCCCCCCEEHHHHHCCEEEEEEEECCCCCCCCEEEEECCCCCCCCHHH
DFIDVAKGLIAKKYTSAGKISIEGRSAGGQVMGVVYNQAPELWGAVLAGVPFVDVINTMI
HHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHCCCHHHHHHHHH
DESLPLTPGEWPEWGNPITDKAAFDYMLSYSPYDNVAAKAYPPMLVSAGLNDPRVTYWEP
HCCCCCCCCCCCCCCCCCCCHHHHHHHEECCCCCCCCHHCCCCEEEECCCCCCCEEEECH
AKWVAKLRATRTNDSLLLLRTNMGAGHAGKSGRWGALREDAEEYAFVLTQLGVEK
HHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]