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The map label for this gene is yafC [C]

Identifier: 103487832

GI number: 103487832

Start: 2475138

End: 2476028

Strand: Direct

Name: yafC [C]

Synonym: Sala_2351

Alternate gene names: 103487832

Gene position: 2475138-2476028 (Clockwise)

Preceding gene: 103487825

Following gene: 103487834

Centisome position: 73.99

GC content: 72.5

Gene sequence:

>891_bases
TTGGACCGGTTGCTGACGCTGGAAATGTTCGTCGCGGTGGCGAGCGAAGGCGGTTTCGCCGCCGCCGCGCGCAAGCTGGG
CAGTTCGCCGCCAGCAGTGACGCGCGGGATCGCGGCGCTTGAGGCGCGGCTCGGCACGGCGCTCTTCCATCGTTCGACGC
GCGCGGTCGCGCTGACCGACGCCGGCGCGGCCTTTCTGGGCGAGGCGCGGCGCATCCTCGCCGACCTCGCGGGCGCCGAA
CGCGCGCTGCGCGGCGCCGCGGCAGCCCCCAGTGGCCAGCTCCACCTCACCGCGCCGGTGATGTTCGGGCGGCTGCACGT
GCTGCCGGTGGTCGATGCGATGATGACCAAGCACCGCGAGCTTGGCGTGCGGATGATGCTGATCGACCGCAACGTCCGTA
TCGTCGAGGAGGGCATCGACGTCGCAGTGCGGATCGGCGCGCTCGCCGATTCGGGGCTGAAGGCGGTGCGCATCGGCCGC
GTGCGCCAGATGCTCGTCGCCAGCCCCGCCTATCTCGCGCGCCGCGGCGCGCCGCACGGCATCGCGGATCTCAAGGGGCA
TGATCTGATCGGCACGATGGGGCCGCGCTGGACGAGCGAATGGCAGTTCGCCCGCGAACGCTGGCGGCTGCCCGCGCCGC
CGCGGTTGACCGTCAACACCGTCGACGGCGCGCTCGCGGCGGCCGAGGCGGGACTGGGGATCGCGAACCTCTTGTCCTAT
CAGCTAGCCGAGGCGATCGACGCGGGGCGGCTGATCGCGCTGCTGGAGCAGGAGCAGCCGCCCGCGCTGCCCGTCCATCT
GCTGTTCGAACCGTCGCGCGCGGCGCTGCCCGCGGTGCGGCTGTTCGTCGAAGCGATGCAGGCGCGTATGCGCATGGCGG
GGCTGGGATGA

Upstream 100 bases:

>100_bases
GGGAGAGGGCGCCTCCGTTCGCAGCGCCGATGTAGGCTATTGCAAAGGACGTGATAATCAGCCATTTTGGTATATCTTAA
TTCCTGTAAGTGGAATAATC

Downstream 100 bases:

>100_bases
AGGGGGGAGCGTTGGGCTGGGAAGCGGACCTTCGTCTTACTGTTGTACCCCGGCGAAAGCCGGGGCCCAGGGCGCCCAGG
AGCAGGCGTTGGCTTATCCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDRLLTLEMFVAVASEGGFAAAARKLGSSPPAVTRGIAALEARLGTALFHRSTRAVALTDAGAAFLGEARRILADLAGAE
RALRGAAAAPSGQLHLTAPVMFGRLHVLPVVDAMMTKHRELGVRMMLIDRNVRIVEEGIDVAVRIGALADSGLKAVRIGR
VRQMLVASPAYLARRGAPHGIADLKGHDLIGTMGPRWTSEWQFARERWRLPAPPRLTVNTVDGALAAAEAGLGIANLLSY
QLAEAIDAGRLIALLEQEQPPALPVHLLFEPSRAALPAVRLFVEAMQARMRMAGLG

Sequences:

>Translated_296_residues
MDRLLTLEMFVAVASEGGFAAAARKLGSSPPAVTRGIAALEARLGTALFHRSTRAVALTDAGAAFLGEARRILADLAGAE
RALRGAAAAPSGQLHLTAPVMFGRLHVLPVVDAMMTKHRELGVRMMLIDRNVRIVEEGIDVAVRIGALADSGLKAVRIGR
VRQMLVASPAYLARRGAPHGIADLKGHDLIGTMGPRWTSEWQFARERWRLPAPPRLTVNTVDGALAAAEAGLGIANLLSY
QLAEAIDAGRLIALLEQEQPPALPVHLLFEPSRAALPAVRLFVEAMQARMRMAGLG
>Mature_296_residues
MDRLLTLEMFVAVASEGGFAAAARKLGSSPPAVTRGIAALEARLGTALFHRSTRAVALTDAGAAFLGEARRILADLAGAE
RALRGAAAAPSGQLHLTAPVMFGRLHVLPVVDAMMTKHRELGVRMMLIDRNVRIVEEGIDVAVRIGALADSGLKAVRIGR
VRQMLVASPAYLARRGAPHGIADLKGHDLIGTMGPRWTSEWQFARERWRLPAPPRLTVNTVDGALAAAEAGLGIANLLSY
QLAEAIDAGRLIALLEQEQPPALPVHLLFEPSRAALPAVRLFVEAMQARMRMAGLG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=30.1369863013699, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI145693193, Length=301, Percent_Identity=29.9003322259136, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787128, Length=282, Percent_Identity=29.4326241134752, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787589, Length=285, Percent_Identity=29.4736842105263, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1789440, Length=252, Percent_Identity=28.5714285714286, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87081978, Length=181, Percent_Identity=37.0165745856354, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789639, Length=272, Percent_Identity=27.9411764705882, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI145693105, Length=250, Percent_Identity=29.6, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787601, Length=117, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789173, Length=294, Percent_Identity=25.1700680272109, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI2367136, Length=298, Percent_Identity=27.1812080536913, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI157672245, Length=153, Percent_Identity=27.4509803921569, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31493; Mature: 31493

Theoretical pI: Translated: 11.34; Mature: 11.34

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLLTLEMFVAVASEGGFAAAARKLGSSPPAVTRGIAALEARLGTALFHRSTRAVALTD
CCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
AGAAFLGEARRILADLAGAERALRGAAAAPSGQLHLTAPVMFGRLHVLPVVDAMMTKHRE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
LGVRMMLIDRNVRIVEEGIDVAVRIGALADSGLKAVRIGRVRQMLVASPAYLARRGAPHG
CCEEEEEEECCCEEEECCCCEEEEEEHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCC
IADLKGHDLIGTMGPRWTSEWQFARERWRLPAPPRLTVNTVDGALAAAEAGLGIANLLSY
CCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHH
QLAEAIDAGRLIALLEQEQPPALPVHLLFEPSRAALPAVRLFVEAMQARMRMAGLG
HHHHHHCCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDRLLTLEMFVAVASEGGFAAAARKLGSSPPAVTRGIAALEARLGTALFHRSTRAVALTD
CCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
AGAAFLGEARRILADLAGAERALRGAAAAPSGQLHLTAPVMFGRLHVLPVVDAMMTKHRE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
LGVRMMLIDRNVRIVEEGIDVAVRIGALADSGLKAVRIGRVRQMLVASPAYLARRGAPHG
CCEEEEEEECCCEEEECCCCEEEEEEHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCC
IADLKGHDLIGTMGPRWTSEWQFARERWRLPAPPRLTVNTVDGALAAAEAGLGIANLLSY
CCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHH
QLAEAIDAGRLIALLEQEQPPALPVHLLFEPSRAALPAVRLFVEAMQARMRMAGLG
HHHHHHCCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]