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The map label for this gene is yfhQ [H]

Identifier: 103487747

GI number: 103487747

Start: 2384752

End: 2385753

Strand: Reverse

Name: yfhQ [H]

Synonym: Sala_2266

Alternate gene names: 103487747

Gene position: 2385753-2384752 (Counterclockwise)

Preceding gene: 103487752

Following gene: 103487746

Centisome position: 71.32

GC content: 72.26

Gene sequence:

>1002_bases
ATGAGTTTTTCTGCGCGGCTGCTCGGCTGGTACGATCGGTCGGCGCGCGTGCTGCCGTGGCGGATCGCGCCGGGGCGCGC
GGAGGTGCCCGACCCCTATCGCGTCTGGCTGGCCGAAGTCATGCTCCAGCAGACGACGGTCGCTGCGGTGGCGGGTTATT
TCGCGCACTTCACGGAGCGTTGGCCGACGGTCGCCGATCTGGCCGCGGCCGGCGATGCCGAGGTCATGGCGGCGTGGGCA
GGGCTTGGCTATTACGCCCGTGCGCGCAACCTGCTGGCCTGCGCGCGCGCCGTCGTCGCCGAGCATGGCGGATGCTTTCC
GGACAGTGAGGCGGGGCTGCGCGCGCTGCCGGGGATCGGCGCCTATACCGCCGCGGCGGTGGCGGCGATCGCCTTTGGCC
GCCCGGCGGTCGTCGTCGACGCCAATATCGAGCGGGTGATCGCGCGCCACCGGTGCATCGAAACGCCGCTCCCCGCCGCG
AAGCGCGCGATTCGCGACGCGCTGGCGCCGCTGGTTCCGGGGGATCGGCCGGGCGATTTCGCGCAGGCGCTGATGGACCT
CGGCGCGACCCTTTGCACGCCGCGCGCGCCCGTGTGCGCGCGCTGCCCGATCGCCGCCGACTGCCGCGCGCGCGGGCGCG
CCGACATCGAGCGGCTGCCGGTCAAGCCGCCGAAGAAGGCCAGGCCGCGCCGCCACGGCGTTGCCCACTGGATCGAGCGA
GACGGCGCGATCTGGCTGGTGCAGCGGCCGGGCAAGGGGATGCTCGGCGGGATGCGCGCGCTGCCCGGCGGCGAATGGTC
GGACGAGCCGCCCGGCGAATCGGGAATCGTCCGCGTCGACCATGGTTTCACCCATTTCGACCTGACGCTGGTTCTCGTCC
GCCGCGAAACGGCCGATGCCGCAGCGGAAGGCATCTGGTGGCCGATCTCGGACCTTGACGCCGCGGGGCTGCCGACGCTC
TATCGCAAGCTGGTGGTCAAGATGCTGGAGAGAGACGCATGA

Upstream 100 bases:

>100_bases
TGGGGGCCATCGGCCTTGCGCAAGGCCGATGGCCCCCACCCGCTGCAACCAGGCAGCAAGCTGCCAAGTGTCGCTGCCCT
CCCCTGAAGGGGAGGGGTTT

Downstream 100 bases:

>100_bases
ACATGATGGTGACGCGCCGCGCGTTGATGGGCGGCATGGCGCTCGGTGGCGCCGCGGCGCTGCTGCCGCGCGCCGCCTGG
GCGTGGCGCGCCGAGGGCGA

Product: HhH-GPD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSFSARLLGWYDRSARVLPWRIAPGRAEVPDPYRVWLAEVMLQQTTVAAVAGYFAHFTERWPTVADLAAAGDAEVMAAWA
GLGYYARARNLLACARAVVAEHGGCFPDSEAGLRALPGIGAYTAAAVAAIAFGRPAVVVDANIERVIARHRCIETPLPAA
KRAIRDALAPLVPGDRPGDFAQALMDLGATLCTPRAPVCARCPIAADCRARGRADIERLPVKPPKKARPRRHGVAHWIER
DGAIWLVQRPGKGMLGGMRALPGGEWSDEPPGESGIVRVDHGFTHFDLTLVLVRRETADAAAEGIWWPISDLDAAGLPTL
YRKLVVKMLERDA

Sequences:

>Translated_333_residues
MSFSARLLGWYDRSARVLPWRIAPGRAEVPDPYRVWLAEVMLQQTTVAAVAGYFAHFTERWPTVADLAAAGDAEVMAAWA
GLGYYARARNLLACARAVVAEHGGCFPDSEAGLRALPGIGAYTAAAVAAIAFGRPAVVVDANIERVIARHRCIETPLPAA
KRAIRDALAPLVPGDRPGDFAQALMDLGATLCTPRAPVCARCPIAADCRARGRADIERLPVKPPKKARPRRHGVAHWIER
DGAIWLVQRPGKGMLGGMRALPGGEWSDEPPGESGIVRVDHGFTHFDLTLVLVRRETADAAAEGIWWPISDLDAAGLPTL
YRKLVVKMLERDA
>Mature_332_residues
SFSARLLGWYDRSARVLPWRIAPGRAEVPDPYRVWLAEVMLQQTTVAAVAGYFAHFTERWPTVADLAAAGDAEVMAAWAG
LGYYARARNLLACARAVVAEHGGCFPDSEAGLRALPGIGAYTAAAVAAIAFGRPAVVVDANIERVIARHRCIETPLPAAK
RAIRDALAPLVPGDRPGDFAQALMDLGATLCTPRAPVCARCPIAADCRARGRADIERLPVKPPKKARPRRHGVAHWIERD
GAIWLVQRPGKGMLGGMRALPGGEWSDEPPGESGIVRVDHGFTHFDLTLVLVRRETADAAAEGIWWPISDLDAAGLPTLY
RKLVVKMLERDA

Specific function: Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal effici

COG id: COG1194

COG function: function code L; A/G-specific DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HhH domain [H]

Homologues:

Organism=Homo sapiens, GI115298648, Length=318, Percent_Identity=40.251572327044, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI115298650, Length=318, Percent_Identity=40.251572327044, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI115298654, Length=318, Percent_Identity=40.251572327044, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI115298652, Length=318, Percent_Identity=40.251572327044, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI6912520, Length=318, Percent_Identity=40.251572327044, Blast_Score=195, Evalue=4e-50,
Organism=Homo sapiens, GI190358497, Length=318, Percent_Identity=40.251572327044, Blast_Score=195, Evalue=4e-50,
Organism=Escherichia coli, GI1789331, Length=308, Percent_Identity=38.3116883116883, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI1787920, Length=189, Percent_Identity=29.1005291005291, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003651
- InterPro:   IPR003265
- InterPro:   IPR023170
- InterPro:   IPR005760
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: 3.2.2.20

Molecular weight: Translated: 35983; Mature: 35852

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS01155 ENDONUCLEASE_III_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSARLLGWYDRSARVLPWRIAPGRAEVPDPYRVWLAEVMLQQTTVAAVAGYFAHFTER
CCCCCCHHEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WPTVADLAAAGDAEVMAAWAGLGYYARARNLLACARAVVAEHGGCFPDSEAGLRALPGIG
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCC
AYTAAAVAAIAFGRPAVVVDANIERVIARHRCIETPLPAAKRAIRDALAPLVPGDRPGDF
HHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHH
AQALMDLGATLCTPRAPVCARCPIAADCRARGRADIERLPVKPPKKARPRRHGVAHWIER
HHHHHHCCHHHCCCCCCCHHCCCCCCCHHCCCCCCHHHCCCCCCHHCCCHHHHHHHHHHC
DGAIWLVQRPGKGMLGGMRALPGGEWSDEPPGESGIVRVDHGFTHFDLTLVLVRRETADA
CCCEEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEEEEEHHHHHH
AAEGIWWPISDLDAAGLPTLYRKLVVKMLERDA
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SFSARLLGWYDRSARVLPWRIAPGRAEVPDPYRVWLAEVMLQQTTVAAVAGYFAHFTER
CCCCCHHEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WPTVADLAAAGDAEVMAAWAGLGYYARARNLLACARAVVAEHGGCFPDSEAGLRALPGIG
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCC
AYTAAAVAAIAFGRPAVVVDANIERVIARHRCIETPLPAAKRAIRDALAPLVPGDRPGDF
HHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHH
AQALMDLGATLCTPRAPVCARCPIAADCRARGRADIERLPVKPPKKARPRRHGVAHWIER
HHHHHHCCHHHCCCCCCCHHCCCCCCCHHCCCCCCHHHCCCCCCHHCCCHHHHHHHHHHC
DGAIWLVQRPGKGMLGGMRALPGGEWSDEPPGESGIVRVDHGFTHFDLTLVLVRRETADA
CCCEEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEEEEEHHHHHH
AAEGIWWPISDLDAAGLPTLYRKLVVKMLERDA
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]