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The map label for this gene is ubiA [H]

Identifier: 103487752

GI number: 103487752

Start: 2391765

End: 2392673

Strand: Reverse

Name: ubiA [H]

Synonym: Sala_2271

Alternate gene names: 103487752

Gene position: 2392673-2391765 (Counterclockwise)

Preceding gene: 103487753

Following gene: 103487747

Centisome position: 71.53

GC content: 69.09

Gene sequence:

>909_bases
ATGACCGCCACCCATCCTCCCGACAGCCAGCTTCGCGGCCTCGTCGCATGGCTTCCCGCCGCGGCGCGGCCCTATGCACT
GCTCGCGCGTTTCGACCGGCCGATCGGCTGGTGGCTGCTGTACTGGCCGTGCGCGTTCGGCGTCGCGCTCGGCGGCGGCG
CGGTCAGCCACTGGCCGCTGTTGCTGTGGTTCCTGCTTGGCGCGATTGCGATGCGCGGGGCGGGGTGCGTCTATAACGAC
ATCGTCGACCGCGATTTCGACGCGAAGGTCGCGCGCACTGCATCGCGGCCGGTGGCGAGCGGGGCGGTGTCGGTGCGGAA
TGCCCTTTTGTGGGCGGTGCTGCTCTCGCTCGTCGGGCTGCTCGTACTCGTCCAGCTGCCGCGCCCGGCGCAGATCGTCG
CATTGGCGAGCCTGATCCTCGTCGCCGCCTACCCCTTCATGAAGCGGATCACCTGGTGGCCGCAGGCGTGGCTGGGGCTG
GTGTTCAGCTGGGGCGCGCTCGTCGCCTGGGTCGCGGTGGGCGGGGTGCAGGGAATGGCGCTGCCTTTGCTTTATGCCGG
CTGCATCGCCTGGGTGATCGGCTATGATACCATCTATGCGCTTCAGGACATCGAGGACGACATGCTCGTCGGCGTCAAAT
CGAGCGCGCGCGCGATGGGCGGGCAGGTGAAGGCCGGGGTCGCGCTCTGCTATGCTGCGGCGCTTGGGCTCTGGGGCGGC
GCGCTGTGGACGGTGCGCCCCGACCCGCTGGTGCTCGTCGCGCTGATTCCGGCGGCGTTGCAACTGACGGGACAGGTTGT
GACGCTCGACGTTGCCAAGGGCGAGGATGCGCTGGCAAAGTTCCGCAGCAACCGCTTCGCCGGATTGCTGGTGTTTGCGG
CGATGCTGGTGGTGGGGACGGCGCCCTGA

Upstream 100 bases:

>100_bases
GCGCGCGACCTGTCGGGCGTCAAAGCACCGGGCACGCCCGCCGCCTGCGATTGATCGGCCATTTATTCGCGGGCGCGCGC
CTGCTATCGCGCGCGAAACG

Downstream 100 bases:

>100_bases
TTCGCTCCTCCCTGTGGCGAAGCCATGGGGAGGTAGCGCACGAAGTGCTGACGGAGGGGCCGTGGCGCGACGTTGCCGCC
CCTCCACCACCGCTTCACGG

Product: 4-hydroxybenzoate polyprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MTATHPPDSQLRGLVAWLPAAARPYALLARFDRPIGWWLLYWPCAFGVALGGGAVSHWPLLLWFLLGAIAMRGAGCVYND
IVDRDFDAKVARTASRPVASGAVSVRNALLWAVLLSLVGLLVLVQLPRPAQIVALASLILVAAYPFMKRITWWPQAWLGL
VFSWGALVAWVAVGGVQGMALPLLYAGCIAWVIGYDTIYALQDIEDDMLVGVKSSARAMGGQVKAGVALCYAAALGLWGG
ALWTVRPDPLVLVALIPAALQLTGQVVTLDVAKGEDALAKFRSNRFAGLLVFAAMLVVGTAP

Sequences:

>Translated_302_residues
MTATHPPDSQLRGLVAWLPAAARPYALLARFDRPIGWWLLYWPCAFGVALGGGAVSHWPLLLWFLLGAIAMRGAGCVYND
IVDRDFDAKVARTASRPVASGAVSVRNALLWAVLLSLVGLLVLVQLPRPAQIVALASLILVAAYPFMKRITWWPQAWLGL
VFSWGALVAWVAVGGVQGMALPLLYAGCIAWVIGYDTIYALQDIEDDMLVGVKSSARAMGGQVKAGVALCYAAALGLWGG
ALWTVRPDPLVLVALIPAALQLTGQVVTLDVAKGEDALAKFRSNRFAGLLVFAAMLVVGTAP
>Mature_301_residues
TATHPPDSQLRGLVAWLPAAARPYALLARFDRPIGWWLLYWPCAFGVALGGGAVSHWPLLLWFLLGAIAMRGAGCVYNDI
VDRDFDAKVARTASRPVASGAVSVRNALLWAVLLSLVGLLVLVQLPRPAQIVALASLILVAAYPFMKRITWWPQAWLGLV
FSWGALVAWVAVGGVQGMALPLLYAGCIAWVIGYDTIYALQDIEDDMLVGVKSSARAMGGQVKAGVALCYAAALGLWGGA
LWTVRPDPLVLVALIPAALQLTGQVVTLDVAKGEDALAKFRSNRFAGLLVFAAMLVVGTAP

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=281, Percent_Identity=42.7046263345196, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=34.9090909090909, Blast_Score=126, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17553718, Length=304, Percent_Identity=39.8026315789474, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI32565247, Length=308, Percent_Identity=38.3116883116883, Blast_Score=175, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17553720, Length=208, Percent_Identity=41.3461538461538, Blast_Score=133, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI32565245, Length=163, Percent_Identity=42.3312883435583, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI32565243, Length=159, Percent_Identity=42.1383647798742, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324370, Length=295, Percent_Identity=37.2881355932203, Blast_Score=160, Evalue=2e-40,
Organism=Drosophila melanogaster, GI21355567, Length=306, Percent_Identity=43.4640522875817, Blast_Score=203, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 32140; Mature: 32009

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATHPPDSQLRGLVAWLPAAARPYALLARFDRPIGWWLLYWPCAFGVALGGGAVSHWPL
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
LLWFLLGAIAMRGAGCVYNDIVDRDFDAKVARTASRPVASGAVSVRNALLWAVLLSLVGL
HHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LVLVQLPRPAQIVALASLILVAAYPFMKRITWWPQAWLGLVFSWGALVAWVAVGGVQGMA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
LPLLYAGCIAWVIGYDTIYALQDIEDDMLVGVKSSARAMGGQVKAGVALCYAAALGLWGG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCC
ALWTVRPDPLVLVALIPAALQLTGQVVTLDVAKGEDALAKFRSNRFAGLLVFAAMLVVGT
CEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHCC
AP
CC
>Mature Secondary Structure 
TATHPPDSQLRGLVAWLPAAARPYALLARFDRPIGWWLLYWPCAFGVALGGGAVSHWPL
CCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
LLWFLLGAIAMRGAGCVYNDIVDRDFDAKVARTASRPVASGAVSVRNALLWAVLLSLVGL
HHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LVLVQLPRPAQIVALASLILVAAYPFMKRITWWPQAWLGLVFSWGALVAWVAVGGVQGMA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
LPLLYAGCIAWVIGYDTIYALQDIEDDMLVGVKSSARAMGGQVKAGVALCYAAALGLWGG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCC
ALWTVRPDPLVLVALIPAALQLTGQVVTLDVAKGEDALAKFRSNRFAGLLVFAAMLVVGT
CEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHCC
AP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA