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The map label for this gene is tlyC [H]

Identifier: 103487639

GI number: 103487639

Start: 2269181

End: 2270125

Strand: Reverse

Name: tlyC [H]

Synonym: Sala_2158

Alternate gene names: 103487639

Gene position: 2270125-2269181 (Counterclockwise)

Preceding gene: 103487640

Following gene: 103487638

Centisome position: 67.86

GC content: 65.61

Gene sequence:

>945_bases
ATGCCCGACGACCAGGGATCTTCGAACCGATCGGAAGAGGACAGTAGCAGGTCCGGGCTGCTGTCCGGACTGAAAAACCT
GCTGTTCGGCGGCGACAAGGAGCCGTCACTGCGCGAACAGATCGAAGAGGTCATCGACGAGGCCGAGGAAGAGGGCGAGG
ACCGCCGCGGCAGCAACATCGTCGGCGACCTTTCGCCCATCGAGCGCAAGATGCTGCGCAACCTCCTCCATTTCGGCGAG
CAGACGGTCGACGATGTCGCGGTGCCGCGCGGCGAGATCATCGCCATCCCCGAAACCGCGAGCTTCGAGGACATCCTCGC
GATCTTTGCCGACGCGGGCCACAGCCGCCTGCCGGTCTATCGCGAAAGCCTCGACGAGGTCATCGGCATGATCCACGTCA
AGGACGTCTTTGCCGTGCTTGCCGAAAAACGGCCACCACCGCCGCTGCTCGACCTCCTCCGTCAGCCGCTCTACGTCCCG
CAATCGATGGGCGTGCTCGACCTGCTCGCCGAAATGCGCGCCAAACGCACCCATCTGGCGATCGTGATCGACGAATATTC
GGGCACCGAGGGATTGCTGACGATCGAGGATCTGGTCGAGGAGATCGTCGGCGAGATCGAGGACGAGCATGACGACGAAC
CCGAGCCGCTGATCGTCGCGGGCGAGGGGGGCTGCTGGGAAGTCGACGCGCGCGCCGAACTCGACGACCTCGGCGAAGCG
GTCGATCCGCGGCTCGGCGAGGTCGAGGAGGATGTCGACACGCTCGGCGGGCTCGCTGCGGTGCTCGCGGGGCATGTGCC
CGAGGTCGGCGAAATACTCGTCCACCCGAGCGGCTGGCGGATCGAGGTGACCGACGCCGACGAACGCCGCGTCCATCATC
TGCGGCTGCATCCGCCGATCGACCTTGATCCCGAAGCGCCATCGGAGCAGCGCGAGGCTTTCTGA

Upstream 100 bases:

>100_bases
TCGGCGGCGGCGATGGAAGCGCTCGAAGTGAAAGCCCTTGCATCGCTGGGCATCGCCAATCCATATGCCGATCAGGATTA
ATTCAGGATATGTTGCAACC

Downstream 100 bases:

>100_bases
CGCAATTGCCTTTGCCCGGCTAACGGATTAGGCGAGGCGGGATGGACGTTTCGGACCTTCGCATCGCCCTGTTCAGCGGC
AATTACAACATGACGACCGA

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MPDDQGSSNRSEEDSSRSGLLSGLKNLLFGGDKEPSLREQIEEVIDEAEEEGEDRRGSNIVGDLSPIERKMLRNLLHFGE
QTVDDVAVPRGEIIAIPETASFEDILAIFADAGHSRLPVYRESLDEVIGMIHVKDVFAVLAEKRPPPPLLDLLRQPLYVP
QSMGVLDLLAEMRAKRTHLAIVIDEYSGTEGLLTIEDLVEEIVGEIEDEHDDEPEPLIVAGEGGCWEVDARAELDDLGEA
VDPRLGEVEEDVDTLGGLAAVLAGHVPEVGEILVHPSGWRIEVTDADERRVHHLRLHPPIDLDPEAPSEQREAF

Sequences:

>Translated_314_residues
MPDDQGSSNRSEEDSSRSGLLSGLKNLLFGGDKEPSLREQIEEVIDEAEEEGEDRRGSNIVGDLSPIERKMLRNLLHFGE
QTVDDVAVPRGEIIAIPETASFEDILAIFADAGHSRLPVYRESLDEVIGMIHVKDVFAVLAEKRPPPPLLDLLRQPLYVP
QSMGVLDLLAEMRAKRTHLAIVIDEYSGTEGLLTIEDLVEEIVGEIEDEHDDEPEPLIVAGEGGCWEVDARAELDDLGEA
VDPRLGEVEEDVDTLGGLAAVLAGHVPEVGEILVHPSGWRIEVTDADERRVHHLRLHPPIDLDPEAPSEQREAF
>Mature_313_residues
PDDQGSSNRSEEDSSRSGLLSGLKNLLFGGDKEPSLREQIEEVIDEAEEEGEDRRGSNIVGDLSPIERKMLRNLLHFGEQ
TVDDVAVPRGEIIAIPETASFEDILAIFADAGHSRLPVYRESLDEVIGMIHVKDVFAVLAEKRPPPPLLDLLRQPLYVPQ
SMGVLDLLAEMRAKRTHLAIVIDEYSGTEGLLTIEDLVEEIVGEIEDEHDDEPEPLIVAGEGGCWEVDARAELDDLGEAV
DPRLGEVEEDVDTLGGLAAVLAGHVPEVGEILVHPSGWRIEVTDADERRVHHLRLHPPIDLDPEAPSEQREAF

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=197, Percent_Identity=31.4720812182741, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1786879, Length=301, Percent_Identity=33.8870431893688, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI145693175, Length=239, Percent_Identity=26.3598326359833, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788119, Length=230, Percent_Identity=30, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082033, Length=243, Percent_Identity=28.3950617283951, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1790664, Length=282, Percent_Identity=24.113475177305, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 34604; Mature: 34473

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDDQGSSNRSEEDSSRSGLLSGLKNLLFGGDKEPSLREQIEEVIDEAEEEGEDRRGSNI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
VGDLSPIERKMLRNLLHFGEQTVDDVAVPRGEIIAIPETASFEDILAIFADAGHSRLPVY
CCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCHH
RESLDEVIGMIHVKDVFAVLAEKRPPPPLLDLLRQPLYVPQSMGVLDLLAEMRAKRTHLA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEE
IVIDEYSGTEGLLTIEDLVEEIVGEIEDEHDDEPEPLIVAGEGGCWEVDARAELDDLGEA
EEEECCCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEECCCCCHHHHHHH
VDPRLGEVEEDVDTLGGLAAVLAGHVPEVGEILVHPSGWRIEVTDADERRVHHLRLHPPI
HCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCEEEEECCHHHHHHEEECCCCC
DLDPEAPSEQREAF
CCCCCCCCHHHCCC
>Mature Secondary Structure 
PDDQGSSNRSEEDSSRSGLLSGLKNLLFGGDKEPSLREQIEEVIDEAEEEGEDRRGSNI
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
VGDLSPIERKMLRNLLHFGEQTVDDVAVPRGEIIAIPETASFEDILAIFADAGHSRLPVY
CCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCHH
RESLDEVIGMIHVKDVFAVLAEKRPPPPLLDLLRQPLYVPQSMGVLDLLAEMRAKRTHLA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEE
IVIDEYSGTEGLLTIEDLVEEIVGEIEDEHDDEPEPLIVAGEGGCWEVDARAELDDLGEA
EEEECCCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEECCCCCHHHHHHH
VDPRLGEVEEDVDTLGGLAAVLAGHVPEVGEILVHPSGWRIEVTDADERRVHHLRLHPPI
HCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCEEEEECCHHHHHHEEECCCCC
DLDPEAPSEQREAF
CCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA