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The map label for this gene is murG

Identifier: 103487365

GI number: 103487365

Start: 1978752

End: 1979930

Strand: Reverse

Name: murG

Synonym: Sala_1881

Alternate gene names: 103487365

Gene position: 1979930-1978752 (Counterclockwise)

Preceding gene: 103487366

Following gene: 103487364

Centisome position: 59.19

GC content: 68.36

Gene sequence:

>1179_bases
ATGACCGCAACGCGCCACTTCCTCCTCGCCGCCGGCGGCACCGGCGGGCATATGCTCCCCGCCTATGCGCTGGCCGACGA
GTTGATCGCGCGCGGGCACCGCGTCGCGCTGGTCAGCGACGACCGCGGGCTGAAGATTCCGGGCGCGCCTGCGGAGCTGG
AAACGCACGTCCTGCCCGCCGGGCGCGCATCGGGCGGGCCCCTCGGCTGGCTGAAGGGCGCGCTTGCGATTCGCAAGGGG
CGACGCATGGCGATCGAGTTGATCGACGACTTCGACCCGGCGGTGGTCGTCGGCTTCGGCGGCTACCCGTCGCTGCCCAG
CCTGCTCGCGGCAGGGGCGACCAAGCGGCCGCGCGTGATCCACGAGCAGAATGCCGTGCTCGGCCGCGTCAACCGGCTGA
TGGCGCCGCGCGTCGATGCGGTGGCGGTCGCCTATCATCATATCCAGCGCTATCCGGCGGGACACGAGCTCAAGATGCAT
ATCACCGGCAATCCGGTGCGTGACGAGATTGTCGCGATCCGCGAGGAAGGTTTTCCGCCGCTGCTCGAGGATGGCATTTT
TCGCCTGCTCGTGGTCGGGGGAAGTTTGGGGGCGACGGTGCTCAGCGAGGTCGTCCCGGCGGCAATCGCCATGCTGCCAC
GCGCGCTGCTCGATCGGCTACAGGTCGTTCAGCAGTGCCGCGAGGATGACCTGGAGGCGGTGCGCGCCCGATATGCCGAA
CTGGGTGTCGCCGCCGAATGTGCGCCTTACATCAAGGATTTCCCTGAGCGGCTGCGTTGGGCGCATATGGTGATTGCACG
CGCGGGTGCGTCGACCGTCGCCGAACTGGCCTGCGCGGGCCGCCCGGCGATCTTCGTGCCCTATCCGCACGCGATGGACG
ATCACCAGACCTATAATGTCGTCGACCTGGTCGAGGCGGGCGGCGCGATTTCGTTCCGGCAGTCCGATTTCATCCCCGCC
GAGGTTGCCAAGCATATCCAGCGCATGGCGGTCGAACCCGGCGTACTCGAAGAGGCGGCCGAACGCGCCGCGAGCTGCGG
GCTTCCCGATGCAACCCGCGACCTTGCCGATCTCGTCGAATCCTTTGCCGCGCCGCCGATGATGGACGTGATCCGTGTTG
GCGCTTCGCTGCCGCGCGCGGCATCGGGTATCGCGGCTGCGCGCCGGGAGGCGAAGTGA

Upstream 100 bases:

>100_bases
TCGATCGGCATGGGTTTGCTCTTGTCGCTGACCCGGCGAAACCCCTATGCGGCGCGGGTGTCGATGACCCGCAACTGGAA
CAAGAAATGATGGCCCCCGC

Downstream 100 bases:

>100_bases
TGCGCGGCGTCGCGACCGACATCGGAACCATCCACTTCATCGGCATCGGCGGCATCGGCATGTCGGGGATCGCCGAGGTG
ATGCATAATCTGGGTTATCG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTATRHFLLAAGGTGGHMLPAYALADELIARGHRVALVSDDRGLKIPGAPAELETHVLPAGRASGGPLGWLKGALAIRKG
RRMAIELIDDFDPAVVVGFGGYPSLPSLLAAGATKRPRVIHEQNAVLGRVNRLMAPRVDAVAVAYHHIQRYPAGHELKMH
ITGNPVRDEIVAIREEGFPPLLEDGIFRLLVVGGSLGATVLSEVVPAAIAMLPRALLDRLQVVQQCREDDLEAVRARYAE
LGVAAECAPYIKDFPERLRWAHMVIARAGASTVAELACAGRPAIFVPYPHAMDDHQTYNVVDLVEAGGAISFRQSDFIPA
EVAKHIQRMAVEPGVLEEAAERAASCGLPDATRDLADLVESFAAPPMMDVIRVGASLPRAASGIAAARREAK

Sequences:

>Translated_392_residues
MTATRHFLLAAGGTGGHMLPAYALADELIARGHRVALVSDDRGLKIPGAPAELETHVLPAGRASGGPLGWLKGALAIRKG
RRMAIELIDDFDPAVVVGFGGYPSLPSLLAAGATKRPRVIHEQNAVLGRVNRLMAPRVDAVAVAYHHIQRYPAGHELKMH
ITGNPVRDEIVAIREEGFPPLLEDGIFRLLVVGGSLGATVLSEVVPAAIAMLPRALLDRLQVVQQCREDDLEAVRARYAE
LGVAAECAPYIKDFPERLRWAHMVIARAGASTVAELACAGRPAIFVPYPHAMDDHQTYNVVDLVEAGGAISFRQSDFIPA
EVAKHIQRMAVEPGVLEEAAERAASCGLPDATRDLADLVESFAAPPMMDVIRVGASLPRAASGIAAARREAK
>Mature_391_residues
TATRHFLLAAGGTGGHMLPAYALADELIARGHRVALVSDDRGLKIPGAPAELETHVLPAGRASGGPLGWLKGALAIRKGR
RMAIELIDDFDPAVVVGFGGYPSLPSLLAAGATKRPRVIHEQNAVLGRVNRLMAPRVDAVAVAYHHIQRYPAGHELKMHI
TGNPVRDEIVAIREEGFPPLLEDGIFRLLVVGGSLGATVLSEVVPAAIAMLPRALLDRLQVVQQCREDDLEAVRARYAEL
GVAAECAPYIKDFPERLRWAHMVIARAGASTVAELACAGRPAIFVPYPHAMDDHQTYNVVDLVEAGGAISFRQSDFIPAE
VAKHIQRMAVEPGVLEEAAERAASCGLPDATRDLADLVESFAAPPMMDVIRVGASLPRAASGIAAARREAK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=369, Percent_Identity=32.2493224932249, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_SPHAL (Q1GRX9)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_616926.1
- ProteinModelPortal:   Q1GRX9
- GeneID:   4082626
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1881
- NMPDR:   fig|317655.9.peg.1809
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   SALA317655:SALA_1881-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 41811; Mature: 41680

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATRHFLLAAGGTGGHMLPAYALADELIARGHRVALVSDDRGLKIPGAPAELETHVLPA
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHEECCC
GRASGGPLGWLKGALAIRKGRRMAIELIDDFDPAVVVGFGGYPSLPSLLAAGATKRPRVI
CCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHCCCCCCCCCH
HEQNAVLGRVNRLMAPRVDAVAVAYHHIQRYPAGHELKMHITGNPVRDEIVAIREEGFPP
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCC
LLEDGIFRLLVVGGSLGATVLSEVVPAAIAMLPRALLDRLQVVQQCREDDLEAVRARYAE
HHHHHHHEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVAAECAPYIKDFPERLRWAHMVIARAGASTVAELACAGRPAIFVPYPHAMDDHQTYNV
HCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCH
VDLVEAGGAISFRQSDFIPAEVAKHIQRMAVEPGVLEEAAERAASCGLPDATRDLADLVE
HHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
SFAAPPMMDVIRVGASLPRAASGIAAARREAK
HHCCCCHHHHHHHCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TATRHFLLAAGGTGGHMLPAYALADELIARGHRVALVSDDRGLKIPGAPAELETHVLPA
CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHEECCC
GRASGGPLGWLKGALAIRKGRRMAIELIDDFDPAVVVGFGGYPSLPSLLAAGATKRPRVI
CCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHCCCCCCCCCH
HEQNAVLGRVNRLMAPRVDAVAVAYHHIQRYPAGHELKMHITGNPVRDEIVAIREEGFPP
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCC
LLEDGIFRLLVVGGSLGATVLSEVVPAAIAMLPRALLDRLQVVQQCREDDLEAVRARYAE
HHHHHHHEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVAAECAPYIKDFPERLRWAHMVIARAGASTVAELACAGRPAIFVPYPHAMDDHQTYNV
HCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCH
VDLVEAGGAISFRQSDFIPAEVAKHIQRMAVEPGVLEEAAERAASCGLPDATRDLADLVE
HHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
SFAAPPMMDVIRVGASLPRAASGIAAARREAK
HHCCCCHHHHHHHCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA