Click here to switch to the map view.

The map label for this gene is mrdB [H]

Identifier: 103487366

GI number: 103487366

Start: 1979941

End: 1981173

Strand: Reverse

Name: mrdB [H]

Synonym: Sala_1882

Alternate gene names: 103487366

Gene position: 1981173-1979941 (Counterclockwise)

Preceding gene: 103487367

Following gene: 103487365

Centisome position: 59.22

GC content: 64.64

Gene sequence:

>1233_bases
ATGAGCGGGGGAGACGATATGGAGACCGCCGAACGCCCGGTAATCGCCGCCACGCGCACGACCAAACGCCGCGGCCCGCG
CTTCAGCCGCGCCGACCGCACCCCGCTTGGCCTGTGGTTCTGGGAAATCGATCGCGTATTGTTGCTGCTCGTGTCGATGC
TGATCGCGATCGGACTGGTCGCGGTTGCTGCGGCGTCGCCGGTCGCGGCGCAAAAATTGTCGACCAGCAGCGCGGCGCTC
GACCCGCTCTATTATTTCTATCGCCAGTTGATGTGGGCAATCGTGGGCGTGCCTGTCATGCTGGCCGTGTCGATGCTGCC
CAAGCCGCAGGCGCGGCGTTTCGCCATTTACGGCACGATCGCCTTCATGGTGCTGCTGTTCCTGGTGCCGCTGGCGGGCA
CGTCGGTGAACGGCGCGCAGCGCTGGATCGGCAGCGGCGCTTTCCGGTTGCAGCCGTCGGAGTTCCTCAAGCCCTTTTTC
GCGGTGTCGCTCGCGTGGATCCTGTCGCTGCGCCTGCACGACCAGAGCCTGCCCGTCGTCCCGCTCGCCGCGGCGCTCAC
CGGCGTCGTCGCGCTCTTGCTGATGGGGCAGCCCGATCTTGGCCAGACGGTGATCTTTGCCGCGACCTGGTTCGTGCTCG
TGCTCGTCGCGGGCCTGTCGATGCGGATCATGGGGATGCTCGCGGGCTCGGGCGTCGCCCTCCTGATCCTTGCCTATTTC
TTCTACCCGGTGGCGCAGCAGCGCATCAATATCTGGCTGTTCGCCGAAGGCGACAGTTTCCAGGTGGACAAGGCGCATGC
GACGCTCACCGCGGGCGGGCTGGTCGGAACCGGCCCCGGCGCGGGTCTCGCCAAGTTCCAGCTGCCCGAAGCGCACACCG
ACTATATCTTCTCGGTGATCGGCGAGGAGTTCGGGATGATCGCCTGCATCGCGATCGCGATCCTCTATCTCGCGATCATC
GTCCGCGTCCTTGTCCGTCTGCTCGATGAAGAGGACAGCTTCCTGATCCTCGCCGTCGCCGGGCTGATCGCGCAGTTCGG
CGGACAGGCGGTGATCAACATGGCGGTGAACACGCAGATCTTTCCGTCAAAGGGAATGACCCTGCCCTTCATCAGCTATG
GCGGCTCGTCGTTCATCGCCTTGTCGATCGGCATGGGTTTGCTCTTGTCGCTGACCCGGCGAAACCCCTATGCGGCGCGG
GTGTCGATGACCCGCAACTGGAACAAGAAATGA

Upstream 100 bases:

>100_bases
CGAGACGCCCATCGGTCTCATATGCCCTCGGGGCATCTCGACTTCGCTCGATGCGAGCGGGGAGAGAAGAGGTCGTGGTA
ATACGACGGGGATGGGGCGC

Downstream 100 bases:

>100_bases
TGGCCCCCGCATGACCGCAACGCGCCACTTCCTCCTCGCCGCCGGCGGCACCGGCGGGCATATGCTCCCCGCCTATGCGC
TGGCCGACGAGTTGATCGCG

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MSGGDDMETAERPVIAATRTTKRRGPRFSRADRTPLGLWFWEIDRVLLLLVSMLIAIGLVAVAAASPVAAQKLSTSSAAL
DPLYYFYRQLMWAIVGVPVMLAVSMLPKPQARRFAIYGTIAFMVLLFLVPLAGTSVNGAQRWIGSGAFRLQPSEFLKPFF
AVSLAWILSLRLHDQSLPVVPLAAALTGVVALLLMGQPDLGQTVIFAATWFVLVLVAGLSMRIMGMLAGSGVALLILAYF
FYPVAQQRINIWLFAEGDSFQVDKAHATLTAGGLVGTGPGAGLAKFQLPEAHTDYIFSVIGEEFGMIACIAIAILYLAII
VRVLVRLLDEEDSFLILAVAGLIAQFGGQAVINMAVNTQIFPSKGMTLPFISYGGSSFIALSIGMGLLLSLTRRNPYAAR
VSMTRNWNKK

Sequences:

>Translated_410_residues
MSGGDDMETAERPVIAATRTTKRRGPRFSRADRTPLGLWFWEIDRVLLLLVSMLIAIGLVAVAAASPVAAQKLSTSSAAL
DPLYYFYRQLMWAIVGVPVMLAVSMLPKPQARRFAIYGTIAFMVLLFLVPLAGTSVNGAQRWIGSGAFRLQPSEFLKPFF
AVSLAWILSLRLHDQSLPVVPLAAALTGVVALLLMGQPDLGQTVIFAATWFVLVLVAGLSMRIMGMLAGSGVALLILAYF
FYPVAQQRINIWLFAEGDSFQVDKAHATLTAGGLVGTGPGAGLAKFQLPEAHTDYIFSVIGEEFGMIACIAIAILYLAII
VRVLVRLLDEEDSFLILAVAGLIAQFGGQAVINMAVNTQIFPSKGMTLPFISYGGSSFIALSIGMGLLLSLTRRNPYAAR
VSMTRNWNKK
>Mature_409_residues
SGGDDMETAERPVIAATRTTKRRGPRFSRADRTPLGLWFWEIDRVLLLLVSMLIAIGLVAVAAASPVAAQKLSTSSAALD
PLYYFYRQLMWAIVGVPVMLAVSMLPKPQARRFAIYGTIAFMVLLFLVPLAGTSVNGAQRWIGSGAFRLQPSEFLKPFFA
VSLAWILSLRLHDQSLPVVPLAAALTGVVALLLMGQPDLGQTVIFAATWFVLVLVAGLSMRIMGMLAGSGVALLILAYFF
YPVAQQRINIWLFAEGDSFQVDKAHATLTAGGLVGTGPGAGLAKFQLPEAHTDYIFSVIGEEFGMIACIAIAILYLAIIV
RVLVRLLDEEDSFLILAVAGLIAQFGGQAVINMAVNTQIFPSKGMTLPFISYGGSSFIALSIGMGLLLSLTRRNPYAARV
SMTRNWNKK

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=370, Percent_Identity=30, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786853, Length=310, Percent_Identity=29.6774193548387, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44262; Mature: 44131

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGDDMETAERPVIAATRTTKRRGPRFSRADRTPLGLWFWEIDRVLLLLVSMLIAIGLV
CCCCCCCHHHCCCEEEEECCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AVAAASPVAAQKLSTSSAALDPLYYFYRQLMWAIVGVPVMLAVSMLPKPQARRFAIYGTI
HHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHH
AFMVLLFLVPLAGTSVNGAQRWIGSGAFRLQPSEFLKPFFAVSLAWILSLRLHDQSLPVV
HHHHHHHHHHHCCCCCCHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
PLAAALTGVVALLLMGQPDLGQTVIFAATWFVLVLVAGLSMRIMGMLAGSGVALLILAYF
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FYPVAQQRINIWLFAEGDSFQVDKAHATLTAGGLVGTGPGAGLAKFQLPEAHTDYIFSVI
HHHHHHCCEEEEEEECCCCEEEECCCEEEEECCEEECCCCCCCEEEECCCCHHHHHHHHH
GEEFGMIACIAIAILYLAIIVRVLVRLLDEEDSFLILAVAGLIAQFGGQAVINMAVNTQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCEEEEEEECCEE
FPSKGMTLPFISYGGSSFIALSIGMGLLLSLTRRNPYAARVSMTRNWNKK
CCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
SGGDDMETAERPVIAATRTTKRRGPRFSRADRTPLGLWFWEIDRVLLLLVSMLIAIGLV
CCCCCCHHHCCCEEEEECCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AVAAASPVAAQKLSTSSAALDPLYYFYRQLMWAIVGVPVMLAVSMLPKPQARRFAIYGTI
HHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHH
AFMVLLFLVPLAGTSVNGAQRWIGSGAFRLQPSEFLKPFFAVSLAWILSLRLHDQSLPVV
HHHHHHHHHHHCCCCCCHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
PLAAALTGVVALLLMGQPDLGQTVIFAATWFVLVLVAGLSMRIMGMLAGSGVALLILAYF
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FYPVAQQRINIWLFAEGDSFQVDKAHATLTAGGLVGTGPGAGLAKFQLPEAHTDYIFSVI
HHHHHHCCEEEEEEECCCCEEEECCCEEEEECCEEECCCCCCCEEEECCCCHHHHHHHHH
GEEFGMIACIAIAILYLAIIVRVLVRLLDEEDSFLILAVAGLIAQFGGQAVINMAVNTQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCEEEEEEECCEE
FPSKGMTLPFISYGGSSFIALSIGMGLLLSLTRRNPYAARVSMTRNWNKK
CCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]