Click here to switch to the map view.

The map label for this gene is wecB [H]

Identifier: 103487075

GI number: 103487075

Start: 1665926

End: 1667050

Strand: Direct

Name: wecB [H]

Synonym: Sala_1590

Alternate gene names: 103487075

Gene position: 1665926-1667050 (Clockwise)

Preceding gene: 103487055

Following gene: 103487076

Centisome position: 49.8

GC content: 65.69

Gene sequence:

>1125_bases
GTGACCGATCATATCGTCATTGCTTTCGGCACTCGCCCGGAAGCGATCAAAATGTTCCCGGTCGTTCGGGCGCTGGCGGC
GCGCGATGACGTTCGGGTCAGCGTCTGCGTCACCGCGCAGCATCGCGAGATGCTCGACCAGGTGCTCGAAATCGCGCGGA
TCACACCCGATATCGACCTTGACGTCATGACACCCGACCAGTCGCTCGATGCGCTGCTCGCGCGGCTCGTCACCGGTCTG
GGCGAAGCCTTCGATGCCGAAAAGCCCGACCGCATCCTCGTCCACGGCGACACGCTGACGACAATGGCGGCGACGCTGGC
CGCCTATTTCCGCAAGATTCCGGTCGGGCATGTCGAGGCGGGGCTGCGCAGCGGCAATATCTATCACCCCTGGCCCGAAG
AGGTGAACCGCAAGGTGACGGGCGCCGTCGCCGACCTGCATTTCGCGCCGACCGAAACCGCCGCGGCGGCGCTGCGCGCC
GAAAATGTGCCTGCCGAGCGCATTCACGTCACCGGCAACACCGTGATCGATGCGCTGCTCGCAACGCAGGCGCGGATCGA
GGAGGAGCCATCGCTGGCCGCGGGGCTCGACCCGCTCGCCCGCCGCTTTGCGGGCAAACGCATCATCGCCGTCACCTCGC
ACCGGCGCGAGAATTTCGGCGACGGCATGAAAGCCATTGCCGAAGCGATCGCCGGGATCGCCGCACGTCCTGACGTGGCG
GTGATTTTCCCGGTTCATCCCAACCCGCATGTCCGCAGCGCGATGGAGCCGATCCTCGGCGCGCTCCCCAATGTCGCGCT
GATCGATCCGCTCGATTATCCGCATTTCGTTCGGCTGCTCGCGCTGAGCACGCTGGTGCTCACCGACAGCGGCGGGGTGC
AGGAGGAAGCGCCCTCGCTCGGCAAGCCGGTGCTCGTGATGCGCGAGACGACCGAGCGGCCCGAAGGCATCGAGGCGGGC
ACCGCACGGCTCGTCGGCACCGACAAAAATCGCATCGTTTCGGAAATTTTCAGCCTTTTGGACGATGAAGGCGCCTATAA
CGCCATGGCGCGCGCGCATAATCCCTTCGGGGACGGCCGCGCCGCGGAACGAATAGCGGAGATTGTTGCGCGTGCCCATC
GATAG

Upstream 100 bases:

>100_bases
AAAGAATGATCGCGTCCATCCAAGGTTAGGACAACGGCAACCCTTTGGATATATAAGGCTGAGCTTGCCTTTTTCAACCG
GATTTCAGGATCGTAGCGAC

Downstream 100 bases:

>100_bases
CGACCAGAATGTTACCGTCCTCGGTCTGGGCTATATCGGCCTGCCCACCGCGGCGTTGATCGCGCGGTCGGGCAGCAAGG
TCACGGGCGTCGATGTCAGC

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MTDHIVIAFGTRPEAIKMFPVVRALAARDDVRVSVCVTAQHREMLDQVLEIARITPDIDLDVMTPDQSLDALLARLVTGL
GEAFDAEKPDRILVHGDTLTTMAATLAAYFRKIPVGHVEAGLRSGNIYHPWPEEVNRKVTGAVADLHFAPTETAAAALRA
ENVPAERIHVTGNTVIDALLATQARIEEEPSLAAGLDPLARRFAGKRIIAVTSHRRENFGDGMKAIAEAIAGIAARPDVA
VIFPVHPNPHVRSAMEPILGALPNVALIDPLDYPHFVRLLALSTLVLTDSGGVQEEAPSLGKPVLVMRETTERPEGIEAG
TARLVGTDKNRIVSEIFSLLDDEGAYNAMARAHNPFGDGRAAERIAEIVARAHR

Sequences:

>Translated_374_residues
MTDHIVIAFGTRPEAIKMFPVVRALAARDDVRVSVCVTAQHREMLDQVLEIARITPDIDLDVMTPDQSLDALLARLVTGL
GEAFDAEKPDRILVHGDTLTTMAATLAAYFRKIPVGHVEAGLRSGNIYHPWPEEVNRKVTGAVADLHFAPTETAAAALRA
ENVPAERIHVTGNTVIDALLATQARIEEEPSLAAGLDPLARRFAGKRIIAVTSHRRENFGDGMKAIAEAIAGIAARPDVA
VIFPVHPNPHVRSAMEPILGALPNVALIDPLDYPHFVRLLALSTLVLTDSGGVQEEAPSLGKPVLVMRETTERPEGIEAG
TARLVGTDKNRIVSEIFSLLDDEGAYNAMARAHNPFGDGRAAERIAEIVARAHR
>Mature_373_residues
TDHIVIAFGTRPEAIKMFPVVRALAARDDVRVSVCVTAQHREMLDQVLEIARITPDIDLDVMTPDQSLDALLARLVTGLG
EAFDAEKPDRILVHGDTLTTMAATLAAYFRKIPVGHVEAGLRSGNIYHPWPEEVNRKVTGAVADLHFAPTETAAAALRAE
NVPAERIHVTGNTVIDALLATQARIEEEPSLAAGLDPLARRFAGKRIIAVTSHRRENFGDGMKAIAEAIAGIAARPDVAV
IFPVHPNPHVRSAMEPILGALPNVALIDPLDYPHFVRLLALSTLVLTDSGGVQEEAPSLGKPVLVMRETTERPEGIEAGT
ARLVGTDKNRIVSEIFSLLDDEGAYNAMARAHNPFGDGRAAERIAEIVARAHR

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=371, Percent_Identity=54.9865229110512, Blast_Score=386, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 40352; Mature: 40221

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDHIVIAFGTRPEAIKMFPVVRALAARDDVRVSVCVTAQHREMLDQVLEIARITPDIDL
CCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCE
DVMTPDQSLDALLARLVTGLGEAFDAEKPDRILVHGDTLTTMAATLAAYFRKIPVGHVEA
EEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCHHHH
GLRSGNIYHPWPEEVNRKVTGAVADLHFAPTETAAAALRAENVPAERIHVTGNTVIDALL
CCCCCCCCCCCHHHHCCHHHHHHHHEECCCCHHHHHHHHHCCCCHHEEEECCHHHHHHHH
ATQARIEEEPSLAAGLDPLARRFAGKRIIAVTSHRRENFGDGMKAIAEAIAGIAARPDVA
HHHHHHCCCCCHHHCCCHHHHHHCCCEEEEEECCCHHCCCHHHHHHHHHHHHHCCCCCEE
VIFPVHPNPHVRSAMEPILGALPNVALIDPLDYPHFVRLLALSTLVLTDSGGVQEEAPSL
EEEECCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHEEECCCCCCCCCCCC
GKPVLVMRETTERPEGIEAGTARLVGTDKNRIVSEIFSLLDDEGAYNAMARAHNPFGDGR
CCCEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCH
AAERIAEIVARAHR
HHHHHHHHHHHHCC
>Mature Secondary Structure 
TDHIVIAFGTRPEAIKMFPVVRALAARDDVRVSVCVTAQHREMLDQVLEIARITPDIDL
CCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCE
DVMTPDQSLDALLARLVTGLGEAFDAEKPDRILVHGDTLTTMAATLAAYFRKIPVGHVEA
EEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCHHHH
GLRSGNIYHPWPEEVNRKVTGAVADLHFAPTETAAAALRAENVPAERIHVTGNTVIDALL
CCCCCCCCCCCHHHHCCHHHHHHHHEECCCCHHHHHHHHHCCCCHHEEEECCHHHHHHHH
ATQARIEEEPSLAAGLDPLARRFAGKRIIAVTSHRRENFGDGMKAIAEAIAGIAARPDVA
HHHHHHCCCCCHHHCCCHHHHHHCCCEEEEEECCCHHCCCHHHHHHHHHHHHHCCCCCEE
VIFPVHPNPHVRSAMEPILGALPNVALIDPLDYPHFVRLLALSTLVLTDSGGVQEEAPSL
EEEECCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHEEECCCCCCCCCCCC
GKPVLVMRETTERPEGIEAGTARLVGTDKNRIVSEIFSLLDDEGAYNAMARAHNPFGDGR
CCCEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCH
AAERIAEIVARAHR
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]