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The map label for this gene is pdxA [H]

Identifier: 103486962

GI number: 103486962

Start: 1537070

End: 1538089

Strand: Direct

Name: pdxA [H]

Synonym: Sala_1477

Alternate gene names: 103486962

Gene position: 1537070-1538089 (Clockwise)

Preceding gene: 103486961

Following gene: 103486963

Centisome position: 45.95

GC content: 70.39

Gene sequence:

>1020_bases
ATGCAAGCCGACGACCATCGGCGTCCGATCGCGGTCACCATGGGCGACCCGGCGGGCGTTGGCCCCGAAGTTACCGCCCG
CGCCTGGGCCGCACGCCACGAGCATGATCTGCCGCCCTTCGTCGCCATCGGCGACATCGCCGCGGTCGAGGCCGTCTGGG
ACGGGCCGATCGCGCGAGTCGGCGACATGGCCGAAGTCGGGCGCGCCTTTGCCGCCGCACTGCCCGTCTGGCACCTCGAG
GACAGCGGCCCGCTGACCCCCGGATCGCCGACTCCCGCCGGCGCGACCTGCGCGCTCCACGCGCTCGAAACGGGCATCGG
ATTGACGCGCAACCAGGCGAGCGCCGCGCTCGTCACCGGATCGGTGTCGAAACATGCGCTGCACGGCATCGGCTATACGC
ACCCCGGCCAGACCGAGTTCATCGCCGAACGCTGCGGCGTCACCGCGACCAATGCGGTGATGATGCTCGCGGGACCGTCG
CTGCGCGTCGTGCCGCTTACCGTGCATATCCCGCTTTCCGAAGTGCCCGAACGGCTGACGAGCGAGTTGATCGTCGCCAA
GGCGCGGATCGTCGCGCGCGGGTTGCGCCGCGACTTCGGCATCGCAACGCCGCGGATCGCGCTCGCCGGCCTCAACCCCC
ATGCCGGGGAGAGTGGCCAATTGGGCGACGAGGAACTCCGCGTCATGCAACCCGCCGTCGCGCAGCTCAGAGAGCAGGGC
CTCACGGTCGACGGTCCGGTCGCCGCCGACGCGCTTTTCGCGCCGGGAATCCGCGACCGCTATGACGCGCTGCTCTGCGC
CTATCACGATCAGGCGCTCGCGCCGTTCAAGGCGCTGCATTTCCACGACGGCGTCAATCTGACGTTGGGGCTGCCAATCG
TCCGTACTTCGCCCGACCATGGCACGGCGTTCAATATCGCGGGCACCGGCCGCGCCGATCCCGGTCCGACGATTGCCGCG
ATCGCGATGGCCGCGCGCATGGCCGCGGCGCGCGAACGCAGCTGCGCGCCGGCAAAGTGA

Upstream 100 bases:

>100_bases
TCGAACAGATTGAGCAGAAGCTGCTGGAAGAAAAGGTCAACAAGCGCGCCCAGCGTTATCTGCGCGACCTGCGCCGCGAC
GCGGTGATCGAATATAGCTG

Downstream 100 bases:

>100_bases
CGATCCAGCCCAGGACGCCGTTGCCGCCACTGCGCGAGACGGTGCGCGTCCACGGTCTGTCGGCGAGCAAGGCGCTGGGA
CAGAACTTTCTCTTCGACGA

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MQADDHRRPIAVTMGDPAGVGPEVTARAWAARHEHDLPPFVAIGDIAAVEAVWDGPIARVGDMAEVGRAFAAALPVWHLE
DSGPLTPGSPTPAGATCALHALETGIGLTRNQASAALVTGSVSKHALHGIGYTHPGQTEFIAERCGVTATNAVMMLAGPS
LRVVPLTVHIPLSEVPERLTSELIVAKARIVARGLRRDFGIATPRIALAGLNPHAGESGQLGDEELRVMQPAVAQLREQG
LTVDGPVAADALFAPGIRDRYDALLCAYHDQALAPFKALHFHDGVNLTLGLPIVRTSPDHGTAFNIAGTGRADPGPTIAA
IAMAARMAAARERSCAPAK

Sequences:

>Translated_339_residues
MQADDHRRPIAVTMGDPAGVGPEVTARAWAARHEHDLPPFVAIGDIAAVEAVWDGPIARVGDMAEVGRAFAAALPVWHLE
DSGPLTPGSPTPAGATCALHALETGIGLTRNQASAALVTGSVSKHALHGIGYTHPGQTEFIAERCGVTATNAVMMLAGPS
LRVVPLTVHIPLSEVPERLTSELIVAKARIVARGLRRDFGIATPRIALAGLNPHAGESGQLGDEELRVMQPAVAQLREQG
LTVDGPVAADALFAPGIRDRYDALLCAYHDQALAPFKALHFHDGVNLTLGLPIVRTSPDHGTAFNIAGTGRADPGPTIAA
IAMAARMAAARERSCAPAK
>Mature_339_residues
MQADDHRRPIAVTMGDPAGVGPEVTARAWAARHEHDLPPFVAIGDIAAVEAVWDGPIARVGDMAEVGRAFAAALPVWHLE
DSGPLTPGSPTPAGATCALHALETGIGLTRNQASAALVTGSVSKHALHGIGYTHPGQTEFIAERCGVTATNAVMMLAGPS
LRVVPLTVHIPLSEVPERLTSELIVAKARIVARGLRRDFGIATPRIALAGLNPHAGESGQLGDEELRVMQPAVAQLREQG
LTVDGPVAADALFAPGIRDRYDALLCAYHDQALAPFKALHFHDGVNLTLGLPIVRTSPDHGTAFNIAGTGRADPGPTIAA
IAMAARMAAARERSCAPAK

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=341, Percent_Identity=36.950146627566, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 35268; Mature: 35268

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQADDHRRPIAVTMGDPAGVGPEVTARAWAARHEHDLPPFVAIGDIAAVEAVWDGPIARV
CCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHCCCHHHH
GDMAEVGRAFAAALPVWHLEDSGPLTPGSPTPAGATCALHALETGIGLTRNQASAALVTG
CCHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEC
SVSKHALHGIGYTHPGQTEFIAERCGVTATNAVMMLAGPSLRVVPLTVHIPLSEVPERLT
CCHHHHHHCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCEEEEEEEEECCHHHHHHHHH
SELIVAKARIVARGLRRDFGIATPRIALAGLNPHAGESGQLGDEELRVMQPAVAQLREQG
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
LTVDGPVAADALFAPGIRDRYDALLCAYHDQALAPFKALHFHDGVNLTLGLPIVRTSPDH
CCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCHHCCHHHHEECCCCEEEECCEEEEECCCC
GTAFNIAGTGRADPGPTIAAIAMAARMAAARERSCAPAK
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQADDHRRPIAVTMGDPAGVGPEVTARAWAARHEHDLPPFVAIGDIAAVEAVWDGPIARV
CCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHCCCHHHH
GDMAEVGRAFAAALPVWHLEDSGPLTPGSPTPAGATCALHALETGIGLTRNQASAALVTG
CCHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEC
SVSKHALHGIGYTHPGQTEFIAERCGVTATNAVMMLAGPSLRVVPLTVHIPLSEVPERLT
CCHHHHHHCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCEEEEEEEEECCHHHHHHHHH
SELIVAKARIVARGLRRDFGIATPRIALAGLNPHAGESGQLGDEELRVMQPAVAQLREQG
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
LTVDGPVAADALFAPGIRDRYDALLCAYHDQALAPFKALHFHDGVNLTLGLPIVRTSPDH
CCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCHHCCHHHHEECCCCEEEECCEEEEECCCC
GTAFNIAGTGRADPGPTIAAIAMAARMAAARERSCAPAK
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA