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The map label for this gene is surA [H]

Identifier: 103486961

GI number: 103486961

Start: 1535730

End: 1537070

Strand: Direct

Name: surA [H]

Synonym: Sala_1476

Alternate gene names: 103486961

Gene position: 1535730-1537070 (Clockwise)

Preceding gene: 103486960

Following gene: 103486962

Centisome position: 45.91

GC content: 62.94

Gene sequence:

>1341_bases
ATGACCAGATTTTCGACCATGACCGGCCTGATCGCGCTGGCGGCCGCCGGTGTAACCCCGGTGCTCGCACAGACCGTTGC
CGATGCCGAAGTGCCCACGACCAGCCTGAACATCCCGGGCAATGTCCAGCTTTATGGTGACAATAAACCCAATGTCTATC
GCCCCTCGGCGACGGTGAATGGCGAGATCATCACTGCGACCGACATCGAACAGCGCATGGCGCTGATCCGGATCGCCAAC
AACAATGTCGAGTTGCCGCCCGAAGAGGAGCAGCGCCTGCGCAATCAGGTATTCAGCAACCTGATCGACGAAAAGCTGCA
GATTCAGGAAGCGCGCGCCGCCGACATCACCATCGACGAAAATGTCGTGAACGAGCAGTTCGCGCGTCTCGCCGCCCGCT
TCAAGCAGACGCCCGAACAATTCGCCGCCTATCTGGCGTCAAAGGGGTCCTCGGCGGCGGCGGTGAAACAGCAGATCCGC
GGCGAGTTTGCCTGGGACCGTCTGCTGTCGCGCAACATCCAGTCGACGACCAATGTGTCGACCGAAGAAGTCGATCTTAT
CGTCAAACAGATGGAAGCCGCCAAGGGGCAGGACGAGTTTCACCTCGGCGAAATCTATCTGTCGGCGACGCCCGACAATA
TCGCCGCAGTTACCGAAAATGCGCGCAAGATCATTCAGGCGCTGCAGGCGGGGGGCAGCTTTGCCGCCTATGCGCGCCAG
TTTTCGGAAGCATCCACGGCGGTCGTCGGGGGCGATCTTGGCTGGGTGAAGGGCGCGCAGCTTCCGGCTTCGATGGCCGA
AGCCGCGATGCAGATGCAGCCCGGCCAACTGGTCGGGCCGATCGAGGTGCCCGGCGGCATTTCGATCATGCTGCTGATCG
ACCGACGACAGGTGCTGACCGCCGACCCGCGCGACGCCATACTCAGCCTGAAGCAGATTTCGCTCGACTTCCCGGCCGGG
ACGACGGAGGCGCAGGCGTCTCAACTTGCGAGCCGCTTTGCGCAGGCGACGCGCACGATCGCCGGTTGTGGTGCGGCCGA
CGCCGTCGCCGAACAATTGGGGGCCAGTGTCGTGTCGCGCGACAATATCGCGATGCGCGCGTTGCCGGCACCGTTGCAGG
CCACGCTCGTCGATCTGCAGGTCGGGCAGACGACGCAGCCGTTCGGCGCCGCGAACGAAGGCATCAGCGTGCTGGTGCTG
TGCGGCCGCGACATGCCCGAGACGGCAACCGCACCCAATCTCGAACAGATTGAGCAGAAGCTGCTGGAAGAAAAGGTCAA
CAAGCGCGCCCAGCGTTATCTGCGCGACCTGCGCCGCGACGCGGTGATCGAATATAGCTGA

Upstream 100 bases:

>100_bases
GCTATTGGCGGGCAACAAATGGCTCCAACGGCGGATTGCGCTGGACCATCGGGCGTGTCCGCTGATACGGAGCGTCCGGA
CTTTCTCGAATAGGGTAAAG

Downstream 100 bases:

>100_bases
TGCAAGCCGACGACCATCGGCGTCCGATCGCGGTCACCATGGGCGACCCGGCGGGCGTTGGCCCCGAAGTTACCGCCCGC
GCCTGGGCCGCACGCCACGA

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MTRFSTMTGLIALAAAGVTPVLAQTVADAEVPTTSLNIPGNVQLYGDNKPNVYRPSATVNGEIITATDIEQRMALIRIAN
NNVELPPEEEQRLRNQVFSNLIDEKLQIQEARAADITIDENVVNEQFARLAARFKQTPEQFAAYLASKGSSAAAVKQQIR
GEFAWDRLLSRNIQSTTNVSTEEVDLIVKQMEAAKGQDEFHLGEIYLSATPDNIAAVTENARKIIQALQAGGSFAAYARQ
FSEASTAVVGGDLGWVKGAQLPASMAEAAMQMQPGQLVGPIEVPGGISIMLLIDRRQVLTADPRDAILSLKQISLDFPAG
TTEAQASQLASRFAQATRTIAGCGAADAVAEQLGASVVSRDNIAMRALPAPLQATLVDLQVGQTTQPFGAANEGISVLVL
CGRDMPETATAPNLEQIEQKLLEEKVNKRAQRYLRDLRRDAVIEYS

Sequences:

>Translated_446_residues
MTRFSTMTGLIALAAAGVTPVLAQTVADAEVPTTSLNIPGNVQLYGDNKPNVYRPSATVNGEIITATDIEQRMALIRIAN
NNVELPPEEEQRLRNQVFSNLIDEKLQIQEARAADITIDENVVNEQFARLAARFKQTPEQFAAYLASKGSSAAAVKQQIR
GEFAWDRLLSRNIQSTTNVSTEEVDLIVKQMEAAKGQDEFHLGEIYLSATPDNIAAVTENARKIIQALQAGGSFAAYARQ
FSEASTAVVGGDLGWVKGAQLPASMAEAAMQMQPGQLVGPIEVPGGISIMLLIDRRQVLTADPRDAILSLKQISLDFPAG
TTEAQASQLASRFAQATRTIAGCGAADAVAEQLGASVVSRDNIAMRALPAPLQATLVDLQVGQTTQPFGAANEGISVLVL
CGRDMPETATAPNLEQIEQKLLEEKVNKRAQRYLRDLRRDAVIEYS
>Mature_445_residues
TRFSTMTGLIALAAAGVTPVLAQTVADAEVPTTSLNIPGNVQLYGDNKPNVYRPSATVNGEIITATDIEQRMALIRIANN
NVELPPEEEQRLRNQVFSNLIDEKLQIQEARAADITIDENVVNEQFARLAARFKQTPEQFAAYLASKGSSAAAVKQQIRG
EFAWDRLLSRNIQSTTNVSTEEVDLIVKQMEAAKGQDEFHLGEIYLSATPDNIAAVTENARKIIQALQAGGSFAAYARQF
SEASTAVVGGDLGWVKGAQLPASMAEAAMQMQPGQLVGPIEVPGGISIMLLIDRRQVLTADPRDAILSLKQISLDFPAGT
TEAQASQLASRFAQATRTIAGCGAADAVAEQLGASVVSRDNIAMRALPAPLQATLVDLQVGQTTQPFGAANEGISVLVLC
GRDMPETATAPNLEQIEQKLLEEKVNKRAQRYLRDLRRDAVIEYS

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=276, Percent_Identity=23.9130434782609, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 48000; Mature: 47869

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRFSTMTGLIALAAAGVTPVLAQTVADAEVPTTSLNIPGNVQLYGDNKPNVYRPSATVN
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCCCCEEEEECCCCCEECCCCCCC
GEIITATDIEQRMALIRIANNNVELPPEEEQRLRNQVFSNLIDEKLQIQEARAADITIDE
CCEEEECCHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECH
NVVNEQFARLAARFKQTPEQFAAYLASKGSSAAAVKQQIRGEFAWDRLLSRNIQSTTNVS
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCC
TEEVDLIVKQMEAAKGQDEFHLGEIYLSATPDNIAAVTENARKIIQALQAGGSFAAYARQ
HHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FSEASTAVVGGDLGWVKGAQLPASMAEAAMQMQPGQLVGPIEVPGGISIMLLIDRRQVLT
HHHHCCEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEECCEECCCCCEEEEEEECCHHHC
ADPRDAILSLKQISLDFPAGTTEAQASQLASRFAQATRTIAGCGAADAVAEQLGASVVSR
CCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
DNIAMRALPAPLQATLVDLQVGQTTQPFGAANEGISVLVLCGRDMPETATAPNLEQIEQK
CCEEEEECCCCHHHEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHH
LLEEKVNKRAQRYLRDLRRDAVIEYS
HHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TRFSTMTGLIALAAAGVTPVLAQTVADAEVPTTSLNIPGNVQLYGDNKPNVYRPSATVN
CCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCCCCEEEEECCCCCEECCCCCCC
GEIITATDIEQRMALIRIANNNVELPPEEEQRLRNQVFSNLIDEKLQIQEARAADITIDE
CCEEEECCHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECH
NVVNEQFARLAARFKQTPEQFAAYLASKGSSAAAVKQQIRGEFAWDRLLSRNIQSTTNVS
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCC
TEEVDLIVKQMEAAKGQDEFHLGEIYLSATPDNIAAVTENARKIIQALQAGGSFAAYARQ
HHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FSEASTAVVGGDLGWVKGAQLPASMAEAAMQMQPGQLVGPIEVPGGISIMLLIDRRQVLT
HHHHCCEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEECCEECCCCCEEEEEEECCHHHC
ADPRDAILSLKQISLDFPAGTTEAQASQLASRFAQATRTIAGCGAADAVAEQLGASVVSR
CCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
DNIAMRALPAPLQATLVDLQVGQTTQPFGAANEGISVLVLCGRDMPETATAPNLEQIEQK
CCEEEEECCCCHHHEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHH
LLEEKVNKRAQRYLRDLRRDAVIEYS
HHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA