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The map label for this gene is pbp [H]

Identifier: 103486945

GI number: 103486945

Start: 1514567

End: 1516138

Strand: Reverse

Name: pbp [H]

Synonym: Sala_1460

Alternate gene names: 103486945

Gene position: 1516138-1514567 (Counterclockwise)

Preceding gene: 103486946

Following gene: 103486944

Centisome position: 45.32

GC content: 64.63

Gene sequence:

>1572_bases
ATGAAACGCCTGCTCGTCCTCACGCTCTTCGTATCGCTCGCGATGCCCGCGTGGGCCGAACCGCCCGCCGACATCGCCGA
AAGCGTCGAGGCGCTGCGGCAGAAAATCGGCGCGCCGGGCGTGTCGATCGCGATCGTAGAGGACGGCAAGACGACGCTGG
CGCGCGGCTGGGGCGTGCGCAAGCTGGGCGAAGCGGCGCCGGTCGATGCCGAGACGATTTTCCAGACCGGATCGACCGGC
AAGGCGATGACCGCGGCGGCGCTCGCCGTGCTCGTCGATGAAGGCAAGATCGGCTGGGACGATCCGGTCATCCAGCATAT
GCCCTGGTTCCGCATGTACGACCCGTGGGTCACGCGCGAGATCACGATCCGCGACCTGCTCGTCCACAGGAGCGGGCTGG
GGCTGGGGCAGGGCGATTTGATGTTCGTGCCGCGCACGCATCTGACGCGCAAACAGACGGTCGAGCGCGTCGCCTATTTG
AAGCCCAAGACCAGTTTCCGTTCGGCCTATGCCTATGACAATATCCTCTACGCCGTCGCGGGCCAGCTGATCGAGGAAGT
CACCGGACAGACGTGGGAGGATTTCATCCGCGCGCGCGTGCTGCGTCCGGGCGGCATGAAAAATGCCACGAGCGACAGCG
AGGAACGCTTCGCGACGCCGAACCGCAGCTGGCCGCACGCGCGCCTGTCCGGCCCATTGCGCGGCATCGGCCCGCAGCAG
ACGCTCGACGAGCGCGACGAGCTGGGCCGCAACGGTGCGCCCGCGGGCGGGCTCGCGCTCAGCGCCGACGATATGGCGGC
GTGGCTCCGCATCCAGCTCGCGCATGGTGCATTACCCGACGGGAAGCGGCTGTTCAGTGAAAAGCAGGCGATGGAGATGT
GGGCGCCGGTGACGCCGATGCCGATCACCCCGCTGCCCGATGCGCTCAAGCCCGCGCAGCCGACGCAGCAGGCCTATGCG
CTCGGCTGGCAGGTGCAGGATTATCGCGGTCATCGCATCATCCAGCATGGTGGCGGCGTATTCGGGTCGATCACCCGCGT
CGTGCTGATCCCCGACAGACAAGTCGGTTTCGCGATCATGATGAACAGCGAGGATAGCGGGATGCTCCTCGGCCTCACCT
ATGATTTGCTCGACCATTATCTCGATCAACCCGACTATGGCTGGATCCAGAAATGGGAGGACTGGTATCAGTCGGGGCTC
GCGGGGGGAGTCGAGTTTCTGAAACAGTCGAAGGCCTCGCCAGCGCAGAGCGGTCCCTCGCTTGCGTTGGCGCGCTATGC
CGGGCGCTACCGCGATCCCTGGTATGGCGATGTCGTGATCGGTTCGGACAGGAAGGGGTTGACGATCGATTTTGCTTCGA
CGCCGCGGATGGCGGGGCGGCTCGATCACTGGCAATATGACAGCTTCGTCACCAGGTTCGACGACCCGGCGATCGAACCC
GCCTATGTCACTTTCGCGCTCGACGCCGATGGCGAGATAACCGGCGTGACGATGAAAGCGGTGAGCAAGATTGCCGACTT
CAGCTGGGATTATCACGATCTCGACCTGAAGCCCGTGGAGGACAAGAAGTGA

Upstream 100 bases:

>100_bases
TCCTCGCCTGGCTTTTCCTCGCCGTTTTCGTGCTGCCGCTCATCACCATCGGCACCTGGCGGCTGCTGCGCCCCGCCGCT
CCCCCCATGGAGGCCCTGCC

Downstream 100 bases:

>100_bases
AGCAACTCGCAATCCTGTTGACCGCGACCGCGCTCGCCGCCTGTTCGACCGGCGGCGACAAGCCCAAGGCAGCCGAAGCC
CCGCTGCACAGCCGGATGCT

Product: beta-lactamase

Products: NA

Alternate protein names: PBP-4 [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MKRLLVLTLFVSLAMPAWAEPPADIAESVEALRQKIGAPGVSIAIVEDGKTTLARGWGVRKLGEAAPVDAETIFQTGSTG
KAMTAAALAVLVDEGKIGWDDPVIQHMPWFRMYDPWVTREITIRDLLVHRSGLGLGQGDLMFVPRTHLTRKQTVERVAYL
KPKTSFRSAYAYDNILYAVAGQLIEEVTGQTWEDFIRARVLRPGGMKNATSDSEERFATPNRSWPHARLSGPLRGIGPQQ
TLDERDELGRNGAPAGGLALSADDMAAWLRIQLAHGALPDGKRLFSEKQAMEMWAPVTPMPITPLPDALKPAQPTQQAYA
LGWQVQDYRGHRIIQHGGGVFGSITRVVLIPDRQVGFAIMMNSEDSGMLLGLTYDLLDHYLDQPDYGWIQKWEDWYQSGL
AGGVEFLKQSKASPAQSGPSLALARYAGRYRDPWYGDVVIGSDRKGLTIDFASTPRMAGRLDHWQYDSFVTRFDDPAIEP
AYVTFALDADGEITGVTMKAVSKIADFSWDYHDLDLKPVEDKK

Sequences:

>Translated_523_residues
MKRLLVLTLFVSLAMPAWAEPPADIAESVEALRQKIGAPGVSIAIVEDGKTTLARGWGVRKLGEAAPVDAETIFQTGSTG
KAMTAAALAVLVDEGKIGWDDPVIQHMPWFRMYDPWVTREITIRDLLVHRSGLGLGQGDLMFVPRTHLTRKQTVERVAYL
KPKTSFRSAYAYDNILYAVAGQLIEEVTGQTWEDFIRARVLRPGGMKNATSDSEERFATPNRSWPHARLSGPLRGIGPQQ
TLDERDELGRNGAPAGGLALSADDMAAWLRIQLAHGALPDGKRLFSEKQAMEMWAPVTPMPITPLPDALKPAQPTQQAYA
LGWQVQDYRGHRIIQHGGGVFGSITRVVLIPDRQVGFAIMMNSEDSGMLLGLTYDLLDHYLDQPDYGWIQKWEDWYQSGL
AGGVEFLKQSKASPAQSGPSLALARYAGRYRDPWYGDVVIGSDRKGLTIDFASTPRMAGRLDHWQYDSFVTRFDDPAIEP
AYVTFALDADGEITGVTMKAVSKIADFSWDYHDLDLKPVEDKK
>Mature_523_residues
MKRLLVLTLFVSLAMPAWAEPPADIAESVEALRQKIGAPGVSIAIVEDGKTTLARGWGVRKLGEAAPVDAETIFQTGSTG
KAMTAAALAVLVDEGKIGWDDPVIQHMPWFRMYDPWVTREITIRDLLVHRSGLGLGQGDLMFVPRTHLTRKQTVERVAYL
KPKTSFRSAYAYDNILYAVAGQLIEEVTGQTWEDFIRARVLRPGGMKNATSDSEERFATPNRSWPHARLSGPLRGIGPQQ
TLDERDELGRNGAPAGGLALSADDMAAWLRIQLAHGALPDGKRLFSEKQAMEMWAPVTPMPITPLPDALKPAQPTQQAYA
LGWQVQDYRGHRIIQHGGGVFGSITRVVLIPDRQVGFAIMMNSEDSGMLLGLTYDLLDHYLDQPDYGWIQKWEDWYQSGL
AGGVEFLKQSKASPAQSGPSLALARYAGRYRDPWYGDVVIGSDRKGLTIDFASTPRMAGRLDHWQYDSFVTRFDDPAIEP
AYVTFALDADGEITGVTMKAVSKIADFSWDYHDLDLKPVEDKK

Specific function: Involved in cell wall biosynthesis and may also act as a sensor of external penicillins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1786574, Length=339, Percent_Identity=23.598820058997, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17550934, Length=356, Percent_Identity=26.123595505618, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 57899; Mature: 57899

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLLVLTLFVSLAMPAWAEPPADIAESVEALRQKIGAPGVSIAIVEDGKTTLARGWGVR
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHCCCCH
KLGEAAPVDAETIFQTGSTGKAMTAAALAVLVDEGKIGWDDPVIQHMPWFRMYDPWVTRE
HHCCCCCCCHHHHHCCCCCCHHHHHHHHHHEEECCCCCCCCHHHHHCCCHHHCCCCCCCE
ITIRDLLVHRSGLGLGQGDLMFVPRTHLTRKQTVERVAYLKPKTSFRSAYAYDNILYAVA
EHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GQLIEEVTGQTWEDFIRARVLRPGGMKNATSDSEERFATPNRSWPHARLSGPLRGIGPQQ
HHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCHHHCCCCCCCCCHH
TLDERDELGRNGAPAGGLALSADDMAAWLRIQLAHGALPDGKRLFSEKQAMEMWAPVTPM
HHHHHHHCCCCCCCCCCEEECHHHHHEEHEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC
PITPLPDALKPAQPTQQAYALGWQVQDYRGHRIIQHGGGVFGSITRVVLIPDRQVGFAIM
CCCCCCCCCCCCCCCHHHHHHCCEEECCCCCEEEECCCCCEECEEEEEEECCCCCCEEEE
MNSEDSGMLLGLTYDLLDHYLDQPDYGWIQKWEDWYQSGLAGGVEFLKQSKASPAQSGPS
ECCCCCCEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LALARYAGRYRDPWYGDVVIGSDRKGLTIDFASTPRMAGRLDHWQYDSFVTRFDDPAIEP
HHHHHHHCCCCCCCCCCEEECCCCCCEEEEECCCCCHHCCCCCCCHHHHHHHCCCCCCCC
AYVTFALDADGEITGVTMKAVSKIADFSWDYHDLDLKPVEDKK
EEEEEEECCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRLLVLTLFVSLAMPAWAEPPADIAESVEALRQKIGAPGVSIAIVEDGKTTLARGWGVR
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHCCCCH
KLGEAAPVDAETIFQTGSTGKAMTAAALAVLVDEGKIGWDDPVIQHMPWFRMYDPWVTRE
HHCCCCCCCHHHHHCCCCCCHHHHHHHHHHEEECCCCCCCCHHHHHCCCHHHCCCCCCCE
ITIRDLLVHRSGLGLGQGDLMFVPRTHLTRKQTVERVAYLKPKTSFRSAYAYDNILYAVA
EHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GQLIEEVTGQTWEDFIRARVLRPGGMKNATSDSEERFATPNRSWPHARLSGPLRGIGPQQ
HHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCHHHCCCCCCCCCHH
TLDERDELGRNGAPAGGLALSADDMAAWLRIQLAHGALPDGKRLFSEKQAMEMWAPVTPM
HHHHHHHCCCCCCCCCCEEECHHHHHEEHEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC
PITPLPDALKPAQPTQQAYALGWQVQDYRGHRIIQHGGGVFGSITRVVLIPDRQVGFAIM
CCCCCCCCCCCCCCCHHHHHHCCEEECCCCCEEEECCCCCEECEEEEEEECCCCCCEEEE
MNSEDSGMLLGLTYDLLDHYLDQPDYGWIQKWEDWYQSGLAGGVEFLKQSKASPAQSGPS
ECCCCCCEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LALARYAGRYRDPWYGDVVIGSDRKGLTIDFASTPRMAGRLDHWQYDSFVTRFDDPAIEP
HHHHHHHCCCCCCCCCCEEECCCCCCEEEEECCCCCHHCCCCCCCHHHHHHHCCCCCCCC
AYVTFALDADGEITGVTMKAVSKIADFSWDYHDLDLKPVEDKK
EEEEEEECCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8440253 [H]