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The map label for this gene is acpS

Identifier: 103486895

GI number: 103486895

Start: 1462724

End: 1463125

Strand: Direct

Name: acpS

Synonym: Sala_1409

Alternate gene names: 103486895

Gene position: 1462724-1463125 (Clockwise)

Preceding gene: 103486894

Following gene: 103486896

Centisome position: 43.73

GC content: 66.92

Gene sequence:

>402_bases
ATGATCATCGGCCTCGGCTCCGACCTCTGTAATATCGAGCGTATCCAGGCTTCGCTCGACCGTTTCGGCGAGCGCTTCGA
AAATCGCGTCTTTACCGACGTCGAGCGCGCCAAGGCGGCGCGGCGGCCGTTCACGCGCGCGGGCACCTACGCCAAGCGGT
TCGCCGCGAAGGAGGCCTTCTCCAAGGCCGTCGGCACCGGCTTCAAGCGCGGCGTGTTCATGAAGGACATCGGCGTCGTC
AACGCGCCGTCGGGGGCGCCGACGCTGGCGCTGACCGGCGGCGCGGCAGAGCGGCTCGCGGCCATGATACCGCCCGGTCA
CACGGCGCATATCCACCTGACATTGACCGACGACCACCCCTGGGCGCAGGCGTTCGTCATCATCGAAGCCATCAAGGACT
GA

Upstream 100 bases:

>100_bases
ATGGCATAGGCTTCCTGTTTTTCACCTGCGTCCTGTATGTGTTTATGCGGTTGATCTTCAAATTTGTGCGCGCGAAGGTC
CAGCACGACGAGCGGCGGTC

Downstream 100 bases:

>100_bases
CCGGATAATGACGAAGAAAAAGACGAAGGATGACGGAAGCTGGGGCAAGCTGATCCGCGATATTGCGGTGATATTGCTGC
TCGTGCTCGCCATCCACAGC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MIIGLGSDLCNIERIQASLDRFGERFENRVFTDVERAKAARRPFTRAGTYAKRFAAKEAFSKAVGTGFKRGVFMKDIGVV
NAPSGAPTLALTGGAAERLAAMIPPGHTAHIHLTLTDDHPWAQAFVIIEAIKD

Sequences:

>Translated_133_residues
MIIGLGSDLCNIERIQASLDRFGERFENRVFTDVERAKAARRPFTRAGTYAKRFAAKEAFSKAVGTGFKRGVFMKDIGVV
NAPSGAPTLALTGGAAERLAAMIPPGHTAHIHLTLTDDHPWAQAFVIIEAIKD
>Mature_133_residues
MIIGLGSDLCNIERIQASLDRFGERFENRVFTDVERAKAARRPFTRAGTYAKRFAAKEAFSKAVGTGFKRGVFMKDIGVV
NAPSGAPTLALTGGAAERLAAMIPPGHTAHIHLTLTDDHPWAQAFVIIEAIKD

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=134, Percent_Identity=41.044776119403, Blast_Score=78, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_SPHAL (Q1GT99)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_616456.1
- ProteinModelPortal:   Q1GT99
- SMR:   Q1GT99
- GeneID:   4081765
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1409
- NMPDR:   fig|317655.9.peg.1342
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   PRK00070
- BioCyc:   SALA317655:SALA_1409-MONOMER
- BRENDA:   2.7.8.7
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14410; Mature: 14410

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGLGSDLCNIERIQASLDRFGERFENRVFTDVERAKAARRPFTRAGTYAKRFAAKEAF
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SKAVGTGFKRGVFMKDIGVVNAPSGAPTLALTGGAAERLAAMIPPGHTAHIHLTLTDDHP
HHHHCCCHHCCEEEHHCCCEECCCCCCEEEEECCHHHHHHHHCCCCCEEEEEEEEECCCC
WAQAFVIIEAIKD
HHHHHHHEEECCC
>Mature Secondary Structure
MIIGLGSDLCNIERIQASLDRFGERFENRVFTDVERAKAARRPFTRAGTYAKRFAAKEAF
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SKAVGTGFKRGVFMKDIGVVNAPSGAPTLALTGGAAERLAAMIPPGHTAHIHLTLTDDHP
HHHHCCCHHCCEEEHHCCCEECCCCCCEEEEECCHHHHHHHHCCCCCEEEEEEEEECCCC
WAQAFVIIEAIKD
HHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA