Click here to switch to the map view.

The map label for this gene is lepB [H]

Identifier: 103486896

GI number: 103486896

Start: 1463133

End: 1463969

Strand: Direct

Name: lepB [H]

Synonym: Sala_1410

Alternate gene names: 103486896

Gene position: 1463133-1463969 (Clockwise)

Preceding gene: 103486895

Following gene: 103486897

Centisome position: 43.74

GC content: 63.32

Gene sequence:

>837_bases
ATGACGAAGAAAAAGACGAAGGATGACGGAAGCTGGGGCAAGCTGATCCGCGATATTGCGGTGATATTGCTGCTCGTGCT
CGCCATCCACAGCTGCGTCGCCAAACCCTTTTACATTCCGTCCGATTCGATGATGCCGATCCTGCGCAACGGCGACCGGC
TGATCGTCAGCAAATATCCCTATGGCTGGTCCTACGCCTCGGTCAGCTTTCACCTTGCGCCCAAGATGGAGGGGCGCCTG
TTCGGCAGGCTGCCCGAACGCGGCGACATCGTCGTGCTCGAACATCCGCTGACGCGCGTCGATTATATCAAGCGCGTGAT
CGGCCTGCCCGGCGATACGATTCAGCTGACGAACGGCGAACTCAGCATCAACGGCAAGCCAGTGAAGCGCGAGGTGCAGC
CGATGCTGGCGATCCCTGTCGATCGCAACACGCCCGGCCCCGATTCCAGCCTGTCGCGCTTCGTCACGCGCGGCGCCGAC
GGGAAGGAACTGCTCGAAATCCCGATCGTCCGCGAAACGCTGCCCGGCGGTGCCAGCTTCGATACGATCGACATGGGCCC
CGGCTATGCCACCGACGATTATGGCCCTTATGTCGTGCCCGCAAATCATCTGTTCCTGATGGGCGACAACCGCGACGGTA
GCGCCGACAGCCGCGTTCCGGCCGAACTGAAGGGCCTGGGCGGCGCGGTGCCGTTCGACGCGATCGCCGGGCGCGCGGAG
ATCATCAGCTTTTCGACCGACGGGACGGCCAAATGGTATAATCCGCTGAGCTGGTTCGAGGCGCTGCGGCCGGGGCGTGC
GGGAACCGACCTGCGGCCCGTGCGTGCAGGCGATTAG

Upstream 100 bases:

>100_bases
CCGCCCGGTCACACGGCGCATATCCACCTGACATTGACCGACGACCACCCCTGGGCGCAGGCGTTCGTCATCATCGAAGC
CATCAAGGACTGACCGGATA

Downstream 100 bases:

>100_bases
CAAACGGGGAACAAGCCATGGCGGAGACGAGGAAGGCAAGCGGGATACGCACCTCCGCCGCCTATGACGCGACGAGCGAG
GCCCCCGGCCCGACCGAAAT

Product: peptidase S26A, signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MTKKKTKDDGSWGKLIRDIAVILLLVLAIHSCVAKPFYIPSDSMMPILRNGDRLIVSKYPYGWSYASVSFHLAPKMEGRL
FGRLPERGDIVVLEHPLTRVDYIKRVIGLPGDTIQLTNGELSINGKPVKREVQPMLAIPVDRNTPGPDSSLSRFVTRGAD
GKELLEIPIVRETLPGGASFDTIDMGPGYATDDYGPYVVPANHLFLMGDNRDGSADSRVPAELKGLGGAVPFDAIAGRAE
IISFSTDGTAKWYNPLSWFEALRPGRAGTDLRPVRAGD

Sequences:

>Translated_278_residues
MTKKKTKDDGSWGKLIRDIAVILLLVLAIHSCVAKPFYIPSDSMMPILRNGDRLIVSKYPYGWSYASVSFHLAPKMEGRL
FGRLPERGDIVVLEHPLTRVDYIKRVIGLPGDTIQLTNGELSINGKPVKREVQPMLAIPVDRNTPGPDSSLSRFVTRGAD
GKELLEIPIVRETLPGGASFDTIDMGPGYATDDYGPYVVPANHLFLMGDNRDGSADSRVPAELKGLGGAVPFDAIAGRAE
IISFSTDGTAKWYNPLSWFEALRPGRAGTDLRPVRAGD
>Mature_277_residues
TKKKTKDDGSWGKLIRDIAVILLLVLAIHSCVAKPFYIPSDSMMPILRNGDRLIVSKYPYGWSYASVSFHLAPKMEGRLF
GRLPERGDIVVLEHPLTRVDYIKRVIGLPGDTIQLTNGELSINGKPVKREVQPMLAIPVDRNTPGPDSSLSRFVTRGADG
KELLEIPIVRETLPGGASFDTIDMGPGYATDDYGPYVVPANHLFLMGDNRDGSADSRVPAELKGLGGAVPFDAIAGRAEI
ISFSTDGTAKWYNPLSWFEALRPGRAGTDLRPVRAGD

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=294, Percent_Identity=29.9319727891156, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 30332; Mature: 30201

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKKTKDDGSWGKLIRDIAVILLLVLAIHSCVAKPFYIPSDSMMPILRNGDRLIVSKYP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHEECCCEEEEEECC
YGWSYASVSFHLAPKMEGRLFGRLPERGDIVVLEHPLTRVDYIKRVIGLPGDTIQLTNGE
CCEEEEEEEEEECCCCCCCEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEECCE
LSINGKPVKREVQPMLAIPVDRNTPGPDSSLSRFVTRGADGKELLEIPIVRETLPGGASF
EEECCCCCHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCHHEEECCHHHHCCCCCCCC
DTIDMGPGYATDDYGPYVVPANHLFLMGDNRDGSADSRVPAELKGLGGAVPFDAIAGRAE
CEEECCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCHHHHCCCCCCCHHHHCCCEE
IISFSTDGTAKWYNPLSWFEALRPGRAGTDLRPVRAGD
EEEECCCCCHHHCCHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKKKTKDDGSWGKLIRDIAVILLLVLAIHSCVAKPFYIPSDSMMPILRNGDRLIVSKYP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHEECCCEEEEEECC
YGWSYASVSFHLAPKMEGRLFGRLPERGDIVVLEHPLTRVDYIKRVIGLPGDTIQLTNGE
CCEEEEEEEEEECCCCCCCEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEECCE
LSINGKPVKREVQPMLAIPVDRNTPGPDSSLSRFVTRGADGKELLEIPIVRETLPGGASF
EEECCCCCHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCHHEEECCHHHHCCCCCCCC
DTIDMGPGYATDDYGPYVVPANHLFLMGDNRDGSADSRVPAELKGLGGAVPFDAIAGRAE
CEEECCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCHHHHCCCCCCCHHHHCCCEE
IISFSTDGTAKWYNPLSWFEALRPGRAGTDLRPVRAGD
EEEECCCCCHHHCCHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA