Click here to switch to the map view.

The map label for this gene is pdxJ [H]

Identifier: 103486893

GI number: 103486893

Start: 1461733

End: 1462479

Strand: Direct

Name: pdxJ [H]

Synonym: Sala_1407

Alternate gene names: 103486893

Gene position: 1461733-1462479 (Clockwise)

Preceding gene: 103486892

Following gene: 103486894

Centisome position: 43.7

GC content: 70.15

Gene sequence:

>747_bases
TTGAACGTCGCGCCCTCTCCGCACCGCCTGCGGCTCGGCGTCAACATCGACCATGTCGCGACGATCCGCAATGCGCGCGG
CGGCGAGCATCCCGACCCGGTGCGCGCGGCGGCGATCGTCGCGGCGGTCGGCGGCGACGGCATCACCGCGCATCTGCGCG
AGGACCGGCGCCATATCCGCGACGACGACCTCGCACGCATCCAGGCGGCGACCGACCTGCCGCTCAACCTCGAAATGGCG
GCGACCGACGAAATGGTCGAGATCGCGCTGCGCCACAAACCGCACGCCGCGTGCATCGTCCCCGAAAAGCGCGAGGAGCG
CACGACCGAGGGCGGGCTGGACGCCGCGGGGCAGCATAATCACCTTGCGCCGATCGTCGCGCGCCTGTCCGACGCGGGCA
TCCGCGTCAGCCTGTTCATCGAGCCCGACGCGCGCCAGATCGAGGCCGCGATGCGCCTGCGCGCGCCGGTGGTCGAGTTT
CACACCGGCCGCTATGCCCATTCAGACGGCGAAGCGCGCGCCGCCGAACTGCGCCGCATCGCCGACGCTGCGGCGCTCGC
GTCGAAGAACGGCATCGAACCGCACGCGGGGCACGGCCTCACCTATGACAATGTCGTCCCCGTCGCCGCGATCCCGCAGC
TCGCCGAACTCAACATCGGCCATTATCTGATCGGCGAGGCGATCTTTACGGGGCTGGAAGATGCGGTGCGGCGAATGCGG
GCGCTGATGGATGAGGCGCGGGGATGA

Upstream 100 bases:

>100_bases
CGCTCGTCGCGATCAACTTCCCGACCTATGCCGCCGACGAACTGCCCCCCGAACTCGCGGGCACCGAGGCGATCAAGCCC
GGCAGCCGGAGTGTGGCAGC

Downstream 100 bases:

>100_bases
AAACGTCCGATTTTGTCGAGAAACAGTGGCGTGCTTCCATTTGGTTTCTCAAGATTTTTCCGTTCTTCATTCTGCTGATT
GTCGTTATAAACATTTGGCA

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNVAPSPHRLRLGVNIDHVATIRNARGGEHPDPVRAAAIVAAVGGDGITAHLREDRRHIRDDDLARIQAATDLPLNLEMA
ATDEMVEIALRHKPHAACIVPEKREERTTEGGLDAAGQHNHLAPIVARLSDAGIRVSLFIEPDARQIEAAMRLRAPVVEF
HTGRYAHSDGEARAAELRRIADAAALASKNGIEPHAGHGLTYDNVVPVAAIPQLAELNIGHYLIGEAIFTGLEDAVRRMR
ALMDEARG

Sequences:

>Translated_248_residues
MNVAPSPHRLRLGVNIDHVATIRNARGGEHPDPVRAAAIVAAVGGDGITAHLREDRRHIRDDDLARIQAATDLPLNLEMA
ATDEMVEIALRHKPHAACIVPEKREERTTEGGLDAAGQHNHLAPIVARLSDAGIRVSLFIEPDARQIEAAMRLRAPVVEF
HTGRYAHSDGEARAAELRRIADAAALASKNGIEPHAGHGLTYDNVVPVAAIPQLAELNIGHYLIGEAIFTGLEDAVRRMR
ALMDEARG
>Mature_248_residues
MNVAPSPHRLRLGVNIDHVATIRNARGGEHPDPVRAAAIVAAVGGDGITAHLREDRRHIRDDDLARIQAATDLPLNLEMA
ATDEMVEIALRHKPHAACIVPEKREERTTEGGLDAAGQHNHLAPIVARLSDAGIRVSLFIEPDARQIEAAMRLRAPVVEF
HTGRYAHSDGEARAAELRRIADAAALASKNGIEPHAGHGLTYDNVVPVAAIPQLAELNIGHYLIGEAIFTGLEDAVRRMR
ALMDEARG

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate [H]

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788917, Length=240, Percent_Identity=57.9166666666667, Blast_Score=269, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004569 [H]

Pfam domain/function: PF03740 PdxJ [H]

EC number: =2.6.99.2 [H]

Molecular weight: Translated: 26788; Mature: 26788

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVAPSPHRLRLGVNIDHVATIRNARGGEHPDPVRAAAIVAAVGGDGITAHLREDRRHIR
CCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHEEEECCCCEEHHHHHHHHHCC
DDDLARIQAATDLPLNLEMAATDEMVEIALRHKPHAACIVPEKREERTTEGGLDAAGQHN
CCHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCEEEECCCHHHHCCCCCCCCCCCCCC
HLAPIVARLSDAGIRVSLFIEPDARQIEAAMRLRAPVVEFHTGRYAHSDGEARAAELRRI
CHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCHHEECCCCEECCCCHHHHHHHHHH
ADAAALASKNGIEPHAGHGLTYDNVVPVAAIPQLAELNIGHYLIGEAIFTGLEDAVRRMR
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ALMDEARG
HHHHHHCC
>Mature Secondary Structure
MNVAPSPHRLRLGVNIDHVATIRNARGGEHPDPVRAAAIVAAVGGDGITAHLREDRRHIR
CCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHEEEECCCCEEHHHHHHHHHCC
DDDLARIQAATDLPLNLEMAATDEMVEIALRHKPHAACIVPEKREERTTEGGLDAAGQHN
CCHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCEEEECCCHHHHCCCCCCCCCCCCCC
HLAPIVARLSDAGIRVSLFIEPDARQIEAAMRLRAPVVEFHTGRYAHSDGEARAAELRRI
CHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCHHEECCCCEECCCCHHHHHHHHHH
ADAAALASKNGIEPHAGHGLTYDNVVPVAAIPQLAELNIGHYLIGEAIFTGLEDAVRRMR
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ALMDEARG
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA