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The map label for this gene is tas [H]

Identifier: 103486849

GI number: 103486849

Start: 1419815

End: 1420831

Strand: Direct

Name: tas [H]

Synonym: Sala_1363

Alternate gene names: 103486849

Gene position: 1419815-1420831 (Clockwise)

Preceding gene: 103486848

Following gene: 103486850

Centisome position: 42.44

GC content: 63.52

Gene sequence:

>1017_bases
ATGCAAAGCCGCCGCCTCGGAAAAAGCGCCATCCATGTGTCCGACATCTGCATGGGGACGATGACCTTCGGCAGCCAGAC
CGACGAGGCGGAGGCGTTCCGCATCCTCGACCGCTGTTTCGACGAGGGGATCAATTTCTATGACACCGCGGAGGGCTATC
CCGTGCCGCCCGACACCCGATGGGTCGGCCGCACCGAGGAGATCGTCGGGCGCTGGCTGAAGACCAAGCCGCGCGACGCC
ATCATCCTCGCGACCAAGGTGTCCGGGCCGAGCCACACCTGGTTCAGGTCGCCGTGCCGTAGCGGCATGACCGCGCTCGA
CCGCAAGAATATCTTTCAGGCGATCGACGACAGCCTGACGCGGCTCCAGACCGATTATGTCGACCTCTATCAGACGCACT
GGCCCGACCATGACGCGCCCTATGACGAGGTGATGGACGCGCTCGATGAACTCGTGCGGATCGGCAAGGTCCGCATCCTC
GGCTGCTCGAACGAGACGAGCTGGGGGCTGATGAAATCGCTCGCGGCATCCGAGCGGCTGGGCGTCGCGCGCTACCACAC
GATCCAGAATAATTTCAGCCTCAACAACCGCCGTTTCGAGGATGAGCTGGCGCAGGTCTGCCGACAGGAAGGCGTCAGCC
TCATCCCCTATTCGCCGCTGGCGGGCGGCGTGCTGTCGGGCAAATATCAGGGCGGCGCGGCGCCGGAGGGCGCGCGCTTT
TCACGCTATCTCGCGATGGAAGGACGGCAGGCGGCGATGGGGCGCCGTTTCGTCAATGAAAAGACGCTCGCCGCGACCGA
ACGCTATCTGAAAATCGCCGCAGACGCCGGACTGCATCCGGTGACGATGGCGACCGCCTGGTCGAAGCAGCATGATTTCG
TCGCCTCGACGATCGTCGGGGTCAGCGCCTACGACCAGCTTGATCCGATCCTCGATGCAAAGGATCTGGTGCTGGAGGGC
GATGTGATGAAGTCGCTGCACAAGGTCGGCAAGGACATCCTCTATCCGATGGGCTGA

Upstream 100 bases:

>100_bases
GGCGTTGCTCGTCGGATCGCTCGCGCTGCTCATGTGATTGCAAGGTTGCTGCTTGCAACCTAAAGACGGCGCTCCCCCTT
CCTGACCGGAGAAGAGAGCC

Downstream 100 bases:

>100_bases
TCGCCTTGCGCCGCGAGCCACGGCCGCTATTCTGGCGCTATCAGAACCAAGGAGTTTCCGCATGCCCCCCATCCGCCGCG
CCTTTTTTGTCGTCGCCGCC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MQSRRLGKSAIHVSDICMGTMTFGSQTDEAEAFRILDRCFDEGINFYDTAEGYPVPPDTRWVGRTEEIVGRWLKTKPRDA
IILATKVSGPSHTWFRSPCRSGMTALDRKNIFQAIDDSLTRLQTDYVDLYQTHWPDHDAPYDEVMDALDELVRIGKVRIL
GCSNETSWGLMKSLAASERLGVARYHTIQNNFSLNNRRFEDELAQVCRQEGVSLIPYSPLAGGVLSGKYQGGAAPEGARF
SRYLAMEGRQAAMGRRFVNEKTLAATERYLKIAADAGLHPVTMATAWSKQHDFVASTIVGVSAYDQLDPILDAKDLVLEG
DVMKSLHKVGKDILYPMG

Sequences:

>Translated_338_residues
MQSRRLGKSAIHVSDICMGTMTFGSQTDEAEAFRILDRCFDEGINFYDTAEGYPVPPDTRWVGRTEEIVGRWLKTKPRDA
IILATKVSGPSHTWFRSPCRSGMTALDRKNIFQAIDDSLTRLQTDYVDLYQTHWPDHDAPYDEVMDALDELVRIGKVRIL
GCSNETSWGLMKSLAASERLGVARYHTIQNNFSLNNRRFEDELAQVCRQEGVSLIPYSPLAGGVLSGKYQGGAAPEGARF
SRYLAMEGRQAAMGRRFVNEKTLAATERYLKIAADAGLHPVTMATAWSKQHDFVASTIVGVSAYDQLDPILDAKDLVLEG
DVMKSLHKVGKDILYPMG
>Mature_338_residues
MQSRRLGKSAIHVSDICMGTMTFGSQTDEAEAFRILDRCFDEGINFYDTAEGYPVPPDTRWVGRTEEIVGRWLKTKPRDA
IILATKVSGPSHTWFRSPCRSGMTALDRKNIFQAIDDSLTRLQTDYVDLYQTHWPDHDAPYDEVMDALDELVRIGKVRIL
GCSNETSWGLMKSLAASERLGVARYHTIQNNFSLNNRRFEDELAQVCRQEGVSLIPYSPLAGGVLSGKYQGGAAPEGARF
SRYLAMEGRQAAMGRRFVNEKTLAATERYLKIAADAGLHPVTMATAWSKQHDFVASTIVGVSAYDQLDPILDAKDLVLEG
DVMKSLHKVGKDILYPMG

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=321, Percent_Identity=29.2834890965732, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI4504825, Length=318, Percent_Identity=29.2452830188679, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI27436964, Length=334, Percent_Identity=28.4431137724551, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI27436966, Length=334, Percent_Identity=28.4431137724551, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI27436962, Length=328, Percent_Identity=28.6585365853659, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI27436971, Length=322, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI41327764, Length=224, Percent_Identity=30.8035714285714, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI223718702, Length=312, Percent_Identity=27.2435897435897, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41152114, Length=217, Percent_Identity=30.8755760368664, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789199, Length=357, Percent_Identity=42.8571428571429, Blast_Score=251, Evalue=5e-68,
Organism=Escherichia coli, GI87081735, Length=336, Percent_Identity=33.0357142857143, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1789375, Length=321, Percent_Identity=29.2834890965732, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788070, Length=327, Percent_Identity=29.0519877675841, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788081, Length=179, Percent_Identity=31.8435754189944, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=242, Percent_Identity=29.3388429752066, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319958, Length=315, Percent_Identity=27.3015873015873, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323998, Length=337, Percent_Identity=27.0029673590504, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319951, Length=348, Percent_Identity=27.2988505747126, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6322615, Length=256, Percent_Identity=26.5625, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6321052, Length=168, Percent_Identity=33.9285714285714, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24640980, Length=367, Percent_Identity=24.7956403269755, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45549126, Length=367, Percent_Identity=24.7956403269755, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24646159, Length=225, Percent_Identity=28.4444444444444, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646155, Length=169, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 37691; Mature: 37691

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSRRLGKSAIHVSDICMGTMTFGSQTDEAEAFRILDRCFDEGINFYDTAEGYPVPPDTR
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCC
WVGRTEEIVGRWLKTKPRDAIILATKVSGPSHTWFRSPCRSGMTALDRKNIFQAIDDSLT
CCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLQTDYVDLYQTHWPDHDAPYDEVMDALDELVRIGKVRILGCSNETSWGLMKSLAASERL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHC
GVARYHTIQNNFSLNNRRFEDELAQVCRQEGVSLIPYSPLAGGVLSGKYQGGAAPEGARF
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCHHH
SRYLAMEGRQAAMGRRFVNEKTLAATERYLKIAADAGLHPVTMATAWSKQHDFVASTIVG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHH
VSAYDQLDPILDAKDLVLEGDVMKSLHKVGKDILYPMG
HHHHHHHHHHCCHHHHEECCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQSRRLGKSAIHVSDICMGTMTFGSQTDEAEAFRILDRCFDEGINFYDTAEGYPVPPDTR
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCC
WVGRTEEIVGRWLKTKPRDAIILATKVSGPSHTWFRSPCRSGMTALDRKNIFQAIDDSLT
CCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLQTDYVDLYQTHWPDHDAPYDEVMDALDELVRIGKVRILGCSNETSWGLMKSLAASERL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHC
GVARYHTIQNNFSLNNRRFEDELAQVCRQEGVSLIPYSPLAGGVLSGKYQGGAAPEGARF
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCHHH
SRYLAMEGRQAAMGRRFVNEKTLAATERYLKIAADAGLHPVTMATAWSKQHDFVASTIVG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHH
VSAYDQLDPILDAKDLVLEGDVMKSLHKVGKDILYPMG
HHHHHHHHHHCCHHHHEECCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]