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The map label for this gene is efp

Identifier: 103486800

GI number: 103486800

Start: 1372574

End: 1373137

Strand: Reverse

Name: efp

Synonym: Sala_1314

Alternate gene names: 103486800

Gene position: 1373137-1372574 (Counterclockwise)

Preceding gene: 103486801

Following gene: 103486799

Centisome position: 41.05

GC content: 59.4

Gene sequence:

>564_bases
ATGAAGATCACCGGCGTTGAAATCCGTCCCGGCAATATAATCGAGTTTGAAGGCGGTATCTGGAAGGTCACCAAAATCCA
GCACACGCAGCCGGGCAAGGGCGGCGCCTATATGCAGGTCGAAGCCAAGAACCTGATCGACGGGCGCAAGCTCAACAACC
GTTTCCGCAGCGCCGACACGGTCGAGAAGGTCCGCCTCGACACCAAGGATTTCCAGTATCTCTATGCCGAAGGCGACGAT
CTCGTCTTCATGGACAAGGATACGTACGAACAGATCACGATCGGCAAGGATGTCGTCGGCGAGGCGCACGAGTTCCTGCA
GGACGGCATGGACGTCGTGCTCGAGCTTTGGGAAGAACGCCCGATCTCGGTCGAACTGCCCGAACAGATCGAAGCCACGA
TCGTCGAGGCCGACGCGGTGGTGAAGGGCCAGACGGCGTCGTCGTCGTACAAGCCCGCGATCCTCGACAATGGCGTGCGT
GTGATGGTGCCTCCGCACATCACCAGCGGCACGCGCATCGTGGTCAATGTGTATGACCGCGAATATGTGCGGCGCGCCGA
TTGA

Upstream 100 bases:

>100_bases
CTTGCCCTTCGGCGCGGGCGCGGCTAAAGGCGCGCTCCTGTGTCCGGCATATAGGCTATGTCGGCGGCTCTTTCCATCCT
TGGCCAAGTGAGTGTGCGCG

Downstream 100 bases:

>100_bases
TTAGTCCCCCTCCCGCTTGCGGGAGGGGTTAGGGGAGGGCGTGTCGAGGGACGGGCCTTTCTCGATAGGAACCGTTCCCT
CCCCCGACCCCTCCCGCAAG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MKITGVEIRPGNIIEFEGGIWKVTKIQHTQPGKGGAYMQVEAKNLIDGRKLNNRFRSADTVEKVRLDTKDFQYLYAEGDD
LVFMDKDTYEQITIGKDVVGEAHEFLQDGMDVVLELWEERPISVELPEQIEATIVEADAVVKGQTASSSYKPAILDNGVR
VMVPPHITSGTRIVVNVYDREYVRRAD

Sequences:

>Translated_187_residues
MKITGVEIRPGNIIEFEGGIWKVTKIQHTQPGKGGAYMQVEAKNLIDGRKLNNRFRSADTVEKVRLDTKDFQYLYAEGDD
LVFMDKDTYEQITIGKDVVGEAHEFLQDGMDVVLELWEERPISVELPEQIEATIVEADAVVKGQTASSSYKPAILDNGVR
VMVPPHITSGTRIVVNVYDREYVRRAD
>Mature_187_residues
MKITGVEIRPGNIIEFEGGIWKVTKIQHTQPGKGGAYMQVEAKNLIDGRKLNNRFRSADTVEKVRLDTKDFQYLYAEGDD
LVFMDKDTYEQITIGKDVVGEAHEFLQDGMDVVLELWEERPISVELPEQIEATIVEADAVVKGQTASSSYKPAILDNGVR
VMVPPHITSGTRIVVNVYDREYVRRAD

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=179, Percent_Identity=32.9608938547486, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI87082061, Length=185, Percent_Identity=30.8108108108108, Blast_Score=99, Evalue=1e-22,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_SPHAL (Q1GTJ4)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_616361.1
- ProteinModelPortal:   Q1GTJ4
- SMR:   Q1GTJ4
- GeneID:   4082238
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1314
- NMPDR:   fig|317655.9.peg.1248
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   SALA317655:SALA_1314-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21086; Mature: 21086

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITGVEIRPGNIIEFEGGIWKVTKIQHTQPGKGGAYMQVEAKNLIDGRKLNNRFRSADT
CCEEEEEECCCCEEEECCCEEEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCC
VEKVRLDTKDFQYLYAEGDDLVFMDKDTYEQITIGKDVVGEAHEFLQDGMDVVLELWEER
HHHHCCCCCCEEEEEECCCEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCC
PISVELPEQIEATIVEADAVVKGQTASSSYKPAILDNGVRVMVPPHITSGTRIVVNVYDR
CCEEECCCHHEEEEEECCEEEECCCCCCCCCCCEECCCCEEEECCCCCCCCEEEEEECCC
EYVRRAD
HHHHCCC
>Mature Secondary Structure
MKITGVEIRPGNIIEFEGGIWKVTKIQHTQPGKGGAYMQVEAKNLIDGRKLNNRFRSADT
CCEEEEEECCCCEEEECCCEEEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCC
VEKVRLDTKDFQYLYAEGDDLVFMDKDTYEQITIGKDVVGEAHEFLQDGMDVVLELWEER
HHHHCCCCCCEEEEEECCCEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCC
PISVELPEQIEATIVEADAVVKGQTASSSYKPAILDNGVRVMVPPHITSGTRIVVNVYDR
CCEEECCCHHEEEEEECCEEEECCCCCCCCCCCEECCCCEEEECCCCCCCCEEEEEECCC
EYVRRAD
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA