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The map label for this gene is lepB [H]

Identifier: 103486702

GI number: 103486702

Start: 1255339

End: 1256220

Strand: Reverse

Name: lepB [H]

Synonym: Sala_1214

Alternate gene names: 103486702

Gene position: 1256220-1255339 (Counterclockwise)

Preceding gene: 103486705

Following gene: 103486701

Centisome position: 37.55

GC content: 62.13

Gene sequence:

>882_bases
ATGACCGAAGCCAGCATTGCCGCCGATAATTCGCCCTCGCCGTCCGCGCCGACGCCCGCTCCCGCTTCGGCGAAGGAAGA
AGCCGTCGACACGGTGCGCTTCCTCGCGCTGCTCGCGATCGCGGTGCTGGTGTTCCGCAGCTTTTTCCTGTCGCCCTTCA
ACATTCCGTCGGAATCGATGCAGCCGCGGCTGCTGATCGGCGACTATCTGCTCGTGAACAAGATGGCCTATGGCTATTCG
AAATACAGCCTGCCGTTCAGCGTTCCGCTGATCCCTGGCCGCATATTTCCGCGCACGCCCGAACGCGGCGATGTCGTGGT
GTTCAAGGCGCCACCGAACGCCGACAATGATTATATCAAGCGCGTGATCGGCCTGCCCGGCGACAGTGTCGAACTGCGCG
ACGGTATCGTGTGGCTCAACGGCGAGCCGCTTCCGCGCGAACCCATGCCCGATTTCGTGATCCCCGTGACGCCGAACATG
ATCGAGGCAGCGCGCGCATCGGGCACCTTGCCCTGCTATGCGATGGAGTTCGAGGAGGTCGGTTCAGATGGTCGGCGCCA
GTGCCGATACAAGCAGTTCCGCGAAACGCTCCCGAACGGGAAAAGCTATGCAATTCTCGACATCGTGCCGATCGCCGAGG
ACAACACGCCGCTCATCATCGTGCCCGAAGGCCATTTGTTTCTGATGGGCGACAACCGCGACCGCAGCGCCGACAGCCGC
TTTCCCGCGATCGAAAATCAGGGCATCGGCCTGGTTCCCGAAGAAAATCTGGTCGGCCATGCCCTTGTCGGCATGTTCTC
GACCGACGGGTCGGCGAGCTGGCTGAATCCGATCAGCTGGTTCACCGCGGCGCGCTGGGATCGCATTGGGGACGGTTTTT
GA

Upstream 100 bases:

>100_bases
GAGATGTCGGCCCTTCTCTAGGCCCGGCACCCGCGCCGCGCCAGCGTCATCCGCCGATATTTGCTTGACGTGGCATCCTA
TTCATCGCCAATGCCGCGGC

Downstream 100 bases:

>100_bases
GCGATCCTCTGAATACCGAGGCGCTGGCCGACATTATCGGCTGCATCCCGGATGATCTGACGCTCTACGACCTTGCGCTG
ACGCACGGCAGCACCGGGCG

Product: peptidase S26A, signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTEASIAADNSPSPSAPTPAPASAKEEAVDTVRFLALLAIAVLVFRSFFLSPFNIPSESMQPRLLIGDYLLVNKMAYGYS
KYSLPFSVPLIPGRIFPRTPERGDVVVFKAPPNADNDYIKRVIGLPGDSVELRDGIVWLNGEPLPREPMPDFVIPVTPNM
IEAARASGTLPCYAMEFEEVGSDGRRQCRYKQFRETLPNGKSYAILDIVPIAEDNTPLIIVPEGHLFLMGDNRDRSADSR
FPAIENQGIGLVPEENLVGHALVGMFSTDGSASWLNPISWFTAARWDRIGDGF

Sequences:

>Translated_293_residues
MTEASIAADNSPSPSAPTPAPASAKEEAVDTVRFLALLAIAVLVFRSFFLSPFNIPSESMQPRLLIGDYLLVNKMAYGYS
KYSLPFSVPLIPGRIFPRTPERGDVVVFKAPPNADNDYIKRVIGLPGDSVELRDGIVWLNGEPLPREPMPDFVIPVTPNM
IEAARASGTLPCYAMEFEEVGSDGRRQCRYKQFRETLPNGKSYAILDIVPIAEDNTPLIIVPEGHLFLMGDNRDRSADSR
FPAIENQGIGLVPEENLVGHALVGMFSTDGSASWLNPISWFTAARWDRIGDGF
>Mature_292_residues
TEASIAADNSPSPSAPTPAPASAKEEAVDTVRFLALLAIAVLVFRSFFLSPFNIPSESMQPRLLIGDYLLVNKMAYGYSK
YSLPFSVPLIPGRIFPRTPERGDVVVFKAPPNADNDYIKRVIGLPGDSVELRDGIVWLNGEPLPREPMPDFVIPVTPNMI
EAARASGTLPCYAMEFEEVGSDGRRQCRYKQFRETLPNGKSYAILDIVPIAEDNTPLIIVPEGHLFLMGDNRDRSADSRF
PAIENQGIGLVPEENLVGHALVGMFSTDGSASWLNPISWFTAARWDRIGDGF

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=282, Percent_Identity=37.2340425531915, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 32171; Mature: 32040

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEASIAADNSPSPSAPTPAPASAKEEAVDTVRFLALLAIAVLVFRSFFLSPFNIPSESM
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHC
QPRLLIGDYLLVNKMAYGYSKYSLPFSVPLIPGRIFPRTPERGDVVVFKAPPNADNDYIK
CCEEEECHHHHHHHHHHCCEEECCCEECCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHH
RVIGLPGDSVELRDGIVWLNGEPLPREPMPDFVIPVTPNMIEAARASGTLPCYAMEFEEV
HHHCCCCCCEEEECCEEEECCCCCCCCCCCCEEEECCCCHHHHHHCCCCCCEEEEEHHHH
GSDGRRQCRYKQFRETLPNGKSYAILDIVPIAEDNTPLIIVPEGHLFLMGDNRDRSADSR
CCCHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCEEEEECCEEEEEECCCCCCCCCC
FPAIENQGIGLVPEENLVGHALVGMFSTDGSASWLNPISWFTAARWDRIGDGF
CCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TEASIAADNSPSPSAPTPAPASAKEEAVDTVRFLALLAIAVLVFRSFFLSPFNIPSESM
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHC
QPRLLIGDYLLVNKMAYGYSKYSLPFSVPLIPGRIFPRTPERGDVVVFKAPPNADNDYIK
CCEEEECHHHHHHHHHHCCEEECCCEECCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHH
RVIGLPGDSVELRDGIVWLNGEPLPREPMPDFVIPVTPNMIEAARASGTLPCYAMEFEEV
HHHCCCCCCEEEECCEEEECCCCCCCCCCCCEEEECCCCHHHHHHCCCCCCEEEEEHHHH
GSDGRRQCRYKQFRETLPNGKSYAILDIVPIAEDNTPLIIVPEGHLFLMGDNRDRSADSR
CCCHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCEEEEECCEEEEEECCCCCCCCCC
FPAIENQGIGLVPEENLVGHALVGMFSTDGSASWLNPISWFTAARWDRIGDGF
CCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]