Click here to switch to the map view.

The map label for this gene is rnc

Identifier: 103486701

GI number: 103486701

Start: 1254662

End: 1255342

Strand: Reverse

Name: rnc

Synonym: Sala_1213

Alternate gene names: 103486701

Gene position: 1255342-1254662 (Counterclockwise)

Preceding gene: 103486702

Following gene: 103486700

Centisome position: 37.53

GC content: 67.99

Gene sequence:

>681_bases
TTGAGCGATCCTCTGAATACCGAGGCGCTGGCCGACATTATCGGCTGCATCCCGGATGATCTGACGCTCTACGACCTTGC
GCTGACGCACGGCAGCACCGGGCGCGCAGACTATCAACGGCTGGAGTTTCTGGGTGACCGCGTGCTCGGGCTTGTCCTGG
CGTCCGAACTCTATACGCGCTTTCCGGCGGCGAGCGAGGGCGAGATGTCGTCGCGGCTGCACGTGCTCGCATCGGGGGCG
ACCTGCGCCGCAATCGCGCAGCGGCTCGACCTGCCCGCGCTGATCCGTTTCGGCGCGCAGGCGCGGAGCGATGGCGGCCG
CCACAGCGACAATATCGCCGCCGATGCGATCGAGGCGCTGATCGGGGCGCTCTTCCTCGAACGAGGCATCGAGGCAGCGC
GTACTTTCATCCTCGCTCAGTGGGGCGCACTGATCGACGGCCAACAGGCCGCGCCGAAGCACCCCAAGGCGGCGCTCCAG
GAATGGGCGCTCGCGCGCGGCCGCCGCCCGCCCGAATATGAAATCGTATCGCGCGAAGGCCCCGACCACGCCCCGCGATT
CCGCATCGCGGTGAGCATCGGCAAGCTCGCGCGTGCCGAGGCGCAGGGCGCATCCAAACAGGCGGCCGAAAAAGCGGCGG
CGGCGGCGCTGCTCGCCGAACTCGAAGGACAGGAAAAATGA

Upstream 100 bases:

>100_bases
ATGCCCTTGTCGGCATGTTCTCGACCGACGGGTCGGCGAGCTGGCTGAATCCGATCAGCTGGTTCACCGCGGCGCGCTGG
GATCGCATTGGGGACGGTTT

Downstream 100 bases:

>100_bases
CCCAGCGCTGCGGTTTTGTCGCCGTCGTCGGTGCGCCCAATGCAGGCAAATCGACCCTCGTAAACGCGCTGGTCGGGCAG
AAGGTCGCCATCGTGAGCCC

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MSDPLNTEALADIIGCIPDDLTLYDLALTHGSTGRADYQRLEFLGDRVLGLVLASELYTRFPAASEGEMSSRLHVLASGA
TCAAIAQRLDLPALIRFGAQARSDGGRHSDNIAADAIEALIGALFLERGIEAARTFILAQWGALIDGQQAAPKHPKAALQ
EWALARGRRPPEYEIVSREGPDHAPRFRIAVSIGKLARAEAQGASKQAAEKAAAAALLAELEGQEK

Sequences:

>Translated_226_residues
MSDPLNTEALADIIGCIPDDLTLYDLALTHGSTGRADYQRLEFLGDRVLGLVLASELYTRFPAASEGEMSSRLHVLASGA
TCAAIAQRLDLPALIRFGAQARSDGGRHSDNIAADAIEALIGALFLERGIEAARTFILAQWGALIDGQQAAPKHPKAALQ
EWALARGRRPPEYEIVSREGPDHAPRFRIAVSIGKLARAEAQGASKQAAEKAAAAALLAELEGQEK
>Mature_225_residues
SDPLNTEALADIIGCIPDDLTLYDLALTHGSTGRADYQRLEFLGDRVLGLVLASELYTRFPAASEGEMSSRLHVLASGAT
CAAIAQRLDLPALIRFGAQARSDGGRHSDNIAADAIEALIGALFLERGIEAARTFILAQWGALIDGQQAAPKHPKAALQE
WALARGRRPPEYEIVSREGPDHAPRFRIAVSIGKLARAEAQGASKQAAEKAAAAALLAELEGQEK

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain

Homologues:

Organism=Escherichia coli, GI1788920, Length=225, Percent_Identity=34.6666666666667, Blast_Score=110, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17506883, Length=195, Percent_Identity=35.3846153846154, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI193202651, Length=195, Percent_Identity=35.3846153846154, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17137682, Length=203, Percent_Identity=30.0492610837438, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNC_SPHAL (Q1GTU3)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_616262.1
- ProteinModelPortal:   Q1GTU3
- SMR:   Q1GTU3
- GeneID:   4080708
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1213
- NMPDR:   fig|317655.9.peg.1147
- HOGENOM:   HBG744556
- OMA:   ALTHKSF
- ProtClustDB:   CLSK835421
- BioCyc:   SALA317655:SALA_1213-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00104
- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907
- Gene3D:   G3DSA:3.30.160.20
- Gene3D:   G3DSA:1.10.1520.10
- SMART:   SM00358
- SMART:   SM00535
- TIGRFAMs:   TIGR02191

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3; SSF69065 RNase_III

EC number: =3.1.26.3

Molecular weight: Translated: 24045; Mature: 23914

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50137 DS_RBD; PS00517 RNASE_3_1; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPLNTEALADIIGCIPDDLTLYDLALTHGSTGRADYQRLEFLGDRVLGLVLASELYTR
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FPAASEGEMSSRLHVLASGATCAAIAQRLDLPALIRFGAQARSDGGRHSDNIAADAIEAL
CCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHCCHHCCCCCCCCCHHHHHHHHHH
IGALFLERGIEAARTFILAQWGALIDGQQAAPKHPKAALQEWALARGRRPPEYEIVSREG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCC
PDHAPRFRIAVSIGKLARAEAQGASKQAAEKAAAAALLAELEGQEK
CCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SDPLNTEALADIIGCIPDDLTLYDLALTHGSTGRADYQRLEFLGDRVLGLVLASELYTR
CCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FPAASEGEMSSRLHVLASGATCAAIAQRLDLPALIRFGAQARSDGGRHSDNIAADAIEAL
CCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHCCHHCCCCCCCCCHHHHHHHHHH
IGALFLERGIEAARTFILAQWGALIDGQQAAPKHPKAALQEWALARGRRPPEYEIVSREG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCC
PDHAPRFRIAVSIGKLARAEAQGASKQAAEKAAAAALLAELEGQEK
CCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA