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The map label for this gene is era [H]

Identifier: 103486700

GI number: 103486700

Start: 1253772

End: 1254665

Strand: Reverse

Name: era [H]

Synonym: Sala_1212

Alternate gene names: 103486700

Gene position: 1254665-1253772 (Counterclockwise)

Preceding gene: 103486701

Following gene: 103486695

Centisome position: 37.51

GC content: 64.21

Gene sequence:

>894_bases
ATGACCCAGCGCTGCGGTTTTGTCGCCGTCGTCGGTGCGCCCAATGCAGGCAAATCGACCCTCGTAAACGCGCTGGTCGG
GCAGAAGGTCGCCATCGTGAGCCCCAAGGCGCAGACAACGCGCACGCGGCTGATGGGCGTCGCGATGGAGGGCGAGACGC
AGATCGTCCTGATCGACACGCCCGGAATCTTTGCTCCTGCCCGCCGACTCGACCGCGCGATGGTCGCCGCCGCATGGGGT
AGTCTCGAGCAGGCCGAGGCTATCCTTGTCATGGTCGACGCGGCCGCGAAACCGACGGGCCGGGTCGAGCGCGTGCTCGA
CGGGATCGCGAACCGGCCCGAAAAAAAATATCTGATCCTGAACAAGGTCGACCTGACCAGAAAGGACAAGCTTCTCACCC
TCGCGACCGACCTCAATGCGAAGCTGACGTTCGACGAGACCTTCTTCATCGCCGCGAGCAGCGGCGACGGTGTGCCCGAA
CTCAAGGCCCATCTTGCCGGGATGATGCCGGAAGGGCCGTGGCACTTCCCCGAAGACGAGGTGAGCGACGCCCCCGAAAG
GATGCTCGCGGCCGAAATCACCCGCGAACAGCTTTACCGCCAGCTCCACGAGGAGTTGCCCTATCAGTCGACCGTCGAGA
CCGAGCTGTTCAGGATGCGCCCCGACGGCAGCGCCGAAATCCACCAGCAAATCTATGTCGCGCGCGACAACCAGCGCGCG
ATCGTGCTCGGCAAGGGCGGCGCCCGCATCAAGGAAATCGGCGCGCGCGCGCGCGCCGAACTGACCGAGCTGATGGGCCG
CAAGGTCCACCTGTTCCTGCACGTCAAGGTGAAGGAAAACTGGGATGAGGACCGCAGCGTCTATCGTGACATGGGGCTTG
ACTGGGTGGATTGA

Upstream 100 bases:

>100_bases
TCGGCAAGCTCGCGCGTGCCGAGGCGCAGGGCGCATCCAAACAGGCGGCCGAAAAAGCGGCGGCGGCGGCGCTGCTCGCC
GAACTCGAAGGACAGGAAAA

Downstream 100 bases:

>100_bases
CGCCCCGCCCTCGTCATCCCCGCCAACGCGGGAATGACGATCAAGGAGGGCGCTACTCGGCCGCCGTCTTCCTGGCGGGT
GCCTCCTTCGCCGCAGCTTT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTQRCGFVAVVGAPNAGKSTLVNALVGQKVAIVSPKAQTTRTRLMGVAMEGETQIVLIDTPGIFAPARRLDRAMVAAAWG
SLEQAEAILVMVDAAAKPTGRVERVLDGIANRPEKKYLILNKVDLTRKDKLLTLATDLNAKLTFDETFFIAASSGDGVPE
LKAHLAGMMPEGPWHFPEDEVSDAPERMLAAEITREQLYRQLHEELPYQSTVETELFRMRPDGSAEIHQQIYVARDNQRA
IVLGKGGARIKEIGARARAELTELMGRKVHLFLHVKVKENWDEDRSVYRDMGLDWVD

Sequences:

>Translated_297_residues
MTQRCGFVAVVGAPNAGKSTLVNALVGQKVAIVSPKAQTTRTRLMGVAMEGETQIVLIDTPGIFAPARRLDRAMVAAAWG
SLEQAEAILVMVDAAAKPTGRVERVLDGIANRPEKKYLILNKVDLTRKDKLLTLATDLNAKLTFDETFFIAASSGDGVPE
LKAHLAGMMPEGPWHFPEDEVSDAPERMLAAEITREQLYRQLHEELPYQSTVETELFRMRPDGSAEIHQQIYVARDNQRA
IVLGKGGARIKEIGARARAELTELMGRKVHLFLHVKVKENWDEDRSVYRDMGLDWVD
>Mature_296_residues
TQRCGFVAVVGAPNAGKSTLVNALVGQKVAIVSPKAQTTRTRLMGVAMEGETQIVLIDTPGIFAPARRLDRAMVAAAWGS
LEQAEAILVMVDAAAKPTGRVERVLDGIANRPEKKYLILNKVDLTRKDKLLTLATDLNAKLTFDETFFIAASSGDGVPEL
KAHLAGMMPEGPWHFPEDEVSDAPERMLAAEITREQLYRQLHEELPYQSTVETELFRMRPDGSAEIHQQIYVARDNQRAI
VLGKGGARIKEIGARARAELTELMGRKVHLFLHVKVKENWDEDRSVYRDMGLDWVD

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=322, Percent_Identity=29.8136645962733, Blast_Score=122, Evalue=3e-28,
Organism=Escherichia coli, GI1788919, Length=295, Percent_Identity=40.3389830508475, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI87082120, Length=180, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI2367268, Length=169, Percent_Identity=33.7278106508876, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646434, Length=311, Percent_Identity=27.0096463022508, Blast_Score=120, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 32942; Mature: 32811

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRCGFVAVVGAPNAGKSTLVNALVGQKVAIVSPKAQTTRTRLMGVAMEGETQIVLIDT
CCCCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHEEEEECCCEEEEEEEC
PGIFAPARRLDRAMVAAAWGSLEQAEAILVMVDAAAKPTGRVERVLDGIANRPEKKYLIL
CCCCHHHHHHHHHHHHHHHCCHHHCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEE
NKVDLTRKDKLLTLATDLNAKLTFDETFFIAASSGDGVPELKAHLAGMMPEGPWHFPEDE
EECCCCCCCCEEEEEECCCCEEEECCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCHH
VSDAPERMLAAEITREQLYRQLHEELPYQSTVETELFRMRPDGSAEIHQQIYVARDNQRA
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCHHHEEEEEEEECCCEE
IVLGKGGARIKEIGARARAELTELMGRKVHLFLHVKVKENWDEDRSVYRDMGLDWVD
EEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQRCGFVAVVGAPNAGKSTLVNALVGQKVAIVSPKAQTTRTRLMGVAMEGETQIVLIDT
CCCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHEEEEECCCEEEEEEEC
PGIFAPARRLDRAMVAAAWGSLEQAEAILVMVDAAAKPTGRVERVLDGIANRPEKKYLIL
CCCCHHHHHHHHHHHHHHHCCHHHCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEE
NKVDLTRKDKLLTLATDLNAKLTFDETFFIAASSGDGVPELKAHLAGMMPEGPWHFPEDE
EECCCCCCCCEEEEEECCCCEEEECCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCHH
VSDAPERMLAAEITREQLYRQLHEELPYQSTVETELFRMRPDGSAEIHQQIYVARDNQRA
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCHHHEEEEEEEECCCEE
IVLGKGGARIKEIGARARAELTELMGRKVHLFLHVKVKENWDEDRSVYRDMGLDWVD
EEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA