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The map label for this gene is lacZ [H]

Identifier: 103486506

GI number: 103486506

Start: 1049490

End: 1051643

Strand: Reverse

Name: lacZ [H]

Synonym: Sala_1017

Alternate gene names: 103486506

Gene position: 1051643-1049490 (Counterclockwise)

Preceding gene: 103486507

Following gene: 103486503

Centisome position: 31.44

GC content: 65.18

Gene sequence:

>2154_bases
ATGCCGCGCTGCCTGACGATGCTGTTCGCGGCGATGCTTGCCGCCTGTTCGGCGGCGCCGCGGCCGACGCCCGCCGCGGC
GCCGCCTTTCACGCGCGACACGACCGAACTGACGCATGGGTGGCAATTCCGCTTCGACGATGGGCTGACGCCCGAAACCG
CGGCCACGCTCGTCGACGGCGCGTGGCAAGATGTCACCGTGCCCCACACATGGAACCGGCTCGGCGAATATCGCATCGGC
CGCACGGCGGCGACCGACAACCGGCAGGGCAAGGGCTGGTATCGCCTGCGCGTCAATGGCGCGGCATTGCCAGCGGGCAA
GCGCCATATCATCGAGTTCGAAGCGGTCGGCAATCTCGCCGACCTATGGGTCAATGGCCGCCATGTCGGGCGCCACGCGG
GCGCTTTCTCCCGCTTCCGCTTCGATCTCACCGATTTTCTGAACCCAGCGGATCCCAACATCATCCTGCTGCGCGCCGAC
AACAGTATGCCCGGACCGGGTAGCAGCACCGAGCATATCATTCCGCTCGACGGCGACTTCTTCATCCACGGCGGCCCCTA
CCGCCCGGCGCGCCTCCTCCACGTCGCGCCGAGCCATATCGCACTCGACGACCATGGCGGGCCCGGCGTCTATGCGACCC
CGACGATCAAAGACGGTGCGGGTCAGGTGGCGATCCGCGTCCGGTTGACCGACATCGCGGCGGGGCAGAGCCTCGTGGCG
ACGCTGCGCGATGCCGGGGGGCGAACCGTCGCCGAAGGCACACGCCCGCTCACCGCGGGTCAGCGCGAGGCCGCGCTGAC
GCTCGACGTCGCCGCGCCGCGCCGCTGGAACGGTCGCGCCGACCCTTATCGCTATCGCCTCGAAACGCGCCTTGCCGATA
CTGGCGGCACGCTCGACAGCGTGACCGTCCCCGTCGGCTTTCGCGCGTTCCGGTTCGACGCGGCAACGGGTTTTTATCTC
AACGGAAAACATCTGCCGCTGCATGGCGTATCGCGACATCAGGATTATCTGGGCAAGGGCTGGGCACTCTCGGCGGAGGA
TCATGCGCGCGACATGGCGCTAATCGCCGAAATGGGCGCGAACACGGTGCGCTTCGCCCATTATCAGCATGCCGCCGACT
GGTTCGACCTTGCCGACCGTTTTGGCATGATCGTCTGGGCCGAACTGCCCTTCGTCAACAAGCCGAGCCACGGCGATGCG
CCCGCATCACCCGAACTGGTCGCCAACGCGCGCCAGCAGATGATCGAGCTGATTCGCCAGAATTACAACCATCCCTCGGT
CGTCACCTGGGGCATCGGCAACGAGGTCGATATGGACATGGCGTTCGGCCGTATGGGACCAAAGGCCGATGCGCGCCCTC
TGCTGCGGGAACTCCATGCGCTGTCGAAGGCCGAAGACCCATCACGCCCGACGGTGATCGCTGACTGCTGCGAACTGACC
CCGGCGAAGAAGCCCGATTACCAGCCGCCACTCACCGGCGAGGCCGACCTGATGGGCTACAACCGCTATTATGGCTGGTA
TTATGGCGAGGTATCCGACCTCGGCCCGCATCTCGACGCTTTGCATGCCAAATATCCGTCCGTGCCGATTTCGGTCAGCG
AATATGGCGCGGGCGGCGCGCTCAGCCAGCATGTCGAGGATCCAGCGCACCACCCGATCAACCCCGGCGGCCGCCCGCAC
CCGGAGGAGTTCCAGAGCTGGCTGCACGAACAAAGCTGGCCGCAACTGCGCGATCGCCGCTATCTATGGGCCAGCTGGAT
ATGGAACATGTTCGATTTTTCGTCGAAAATCCGAAAGGAAGGCGACGCGACCGACATCAACGACAAGGGCCTCGTCACCT
TCGACCGCAAGGTCAAGAAGGACGCCTTTTTCTATTACAAGGCCCAATGGTCGACCGAACCCGTCGTCCATATCACCAGC
CGTCGCTGGACGACGCGCGCCAGTCCCGTCACGGCGATCAAGGTTTACAGTAACGCGCCCGCCGTGACGCTGACGTTCAA
CGGGGTGCCGCTGGGCGAGGTCGCGTGCGCCGATCGCATCTGCACGCTGGACAATATCGTGCTGCGCCCCGGCGACAATG
TGGTGACGGCGCGCGCGACCTTTGCATCCGGGGTGGTGAAGGACGAAGTGCGCTGGACCCTTACGCCGCTCTAA

Upstream 100 bases:

>100_bases
TGCTTCGTCATGCGACGCTGACGCAGCAAACGGGCGGCAAGCTGCCATCGGATCATTATCCGGTGCTCGCCGACCTGTGC
GTGGGCAGGGGGTGCTGACG

Downstream 100 bases:

>100_bases
AAACGGCCTATTCGCCCTTTGCTGGCTGCGCCTGATCGAGCCAGCCGCCGGTGAAGCCGATGCGTTTCAGTCCGCGCACG
ATATGCCGATTCCTGCGCAT

Product: Beta-galactosidase

Products: NA

Alternate protein names: Beta-gal; Lactase [H]

Number of amino acids: Translated: 717; Mature: 716

Protein sequence:

>717_residues
MPRCLTMLFAAMLAACSAAPRPTPAAAPPFTRDTTELTHGWQFRFDDGLTPETAATLVDGAWQDVTVPHTWNRLGEYRIG
RTAATDNRQGKGWYRLRVNGAALPAGKRHIIEFEAVGNLADLWVNGRHVGRHAGAFSRFRFDLTDFLNPADPNIILLRAD
NSMPGPGSSTEHIIPLDGDFFIHGGPYRPARLLHVAPSHIALDDHGGPGVYATPTIKDGAGQVAIRVRLTDIAAGQSLVA
TLRDAGGRTVAEGTRPLTAGQREAALTLDVAAPRRWNGRADPYRYRLETRLADTGGTLDSVTVPVGFRAFRFDAATGFYL
NGKHLPLHGVSRHQDYLGKGWALSAEDHARDMALIAEMGANTVRFAHYQHAADWFDLADRFGMIVWAELPFVNKPSHGDA
PASPELVANARQQMIELIRQNYNHPSVVTWGIGNEVDMDMAFGRMGPKADARPLLRELHALSKAEDPSRPTVIADCCELT
PAKKPDYQPPLTGEADLMGYNRYYGWYYGEVSDLGPHLDALHAKYPSVPISVSEYGAGGALSQHVEDPAHHPINPGGRPH
PEEFQSWLHEQSWPQLRDRRYLWASWIWNMFDFSSKIRKEGDATDINDKGLVTFDRKVKKDAFFYYKAQWSTEPVVHITS
RRWTTRASPVTAIKVYSNAPAVTLTFNGVPLGEVACADRICTLDNIVLRPGDNVVTARATFASGVVKDEVRWTLTPL

Sequences:

>Translated_717_residues
MPRCLTMLFAAMLAACSAAPRPTPAAAPPFTRDTTELTHGWQFRFDDGLTPETAATLVDGAWQDVTVPHTWNRLGEYRIG
RTAATDNRQGKGWYRLRVNGAALPAGKRHIIEFEAVGNLADLWVNGRHVGRHAGAFSRFRFDLTDFLNPADPNIILLRAD
NSMPGPGSSTEHIIPLDGDFFIHGGPYRPARLLHVAPSHIALDDHGGPGVYATPTIKDGAGQVAIRVRLTDIAAGQSLVA
TLRDAGGRTVAEGTRPLTAGQREAALTLDVAAPRRWNGRADPYRYRLETRLADTGGTLDSVTVPVGFRAFRFDAATGFYL
NGKHLPLHGVSRHQDYLGKGWALSAEDHARDMALIAEMGANTVRFAHYQHAADWFDLADRFGMIVWAELPFVNKPSHGDA
PASPELVANARQQMIELIRQNYNHPSVVTWGIGNEVDMDMAFGRMGPKADARPLLRELHALSKAEDPSRPTVIADCCELT
PAKKPDYQPPLTGEADLMGYNRYYGWYYGEVSDLGPHLDALHAKYPSVPISVSEYGAGGALSQHVEDPAHHPINPGGRPH
PEEFQSWLHEQSWPQLRDRRYLWASWIWNMFDFSSKIRKEGDATDINDKGLVTFDRKVKKDAFFYYKAQWSTEPVVHITS
RRWTTRASPVTAIKVYSNAPAVTLTFNGVPLGEVACADRICTLDNIVLRPGDNVVTARATFASGVVKDEVRWTLTPL
>Mature_716_residues
PRCLTMLFAAMLAACSAAPRPTPAAAPPFTRDTTELTHGWQFRFDDGLTPETAATLVDGAWQDVTVPHTWNRLGEYRIGR
TAATDNRQGKGWYRLRVNGAALPAGKRHIIEFEAVGNLADLWVNGRHVGRHAGAFSRFRFDLTDFLNPADPNIILLRADN
SMPGPGSSTEHIIPLDGDFFIHGGPYRPARLLHVAPSHIALDDHGGPGVYATPTIKDGAGQVAIRVRLTDIAAGQSLVAT
LRDAGGRTVAEGTRPLTAGQREAALTLDVAAPRRWNGRADPYRYRLETRLADTGGTLDSVTVPVGFRAFRFDAATGFYLN
GKHLPLHGVSRHQDYLGKGWALSAEDHARDMALIAEMGANTVRFAHYQHAADWFDLADRFGMIVWAELPFVNKPSHGDAP
ASPELVANARQQMIELIRQNYNHPSVVTWGIGNEVDMDMAFGRMGPKADARPLLRELHALSKAEDPSRPTVIADCCELTP
AKKPDYQPPLTGEADLMGYNRYYGWYYGEVSDLGPHLDALHAKYPSVPISVSEYGAGGALSQHVEDPAHHPINPGGRPHP
EEFQSWLHEQSWPQLRDRRYLWASWIWNMFDFSSKIRKEGDATDINDKGLVTFDRKVKKDAFFYYKAQWSTEPVVHITSR
RWTTRASPVTAIKVYSNAPAVTLTFNGVPLGEVACADRICTLDNIVLRPGDNVVTARATFASGVVKDEVRWTLTPL

Specific function: Unknown

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=560, Percent_Identity=26.6071428571429, Blast_Score=138, Evalue=1e-32,
Organism=Escherichia coli, GI1787903, Length=577, Percent_Identity=26.6897746967071, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI48994920, Length=446, Percent_Identity=26.6816143497758, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI1786539, Length=403, Percent_Identity=27.2952853598015, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17510825, Length=643, Percent_Identity=23.1726283048211, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24655438, Length=551, Percent_Identity=26.6787658802178, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI62471735, Length=551, Percent_Identity=26.6787658802178, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI19922582, Length=551, Percent_Identity=26.6787658802178, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24651745, Length=580, Percent_Identity=26.0344827586207, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 79207; Mature: 79076

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRCLTMLFAAMLAACSAAPRPTPAAAPPFTRDTTELTHGWQFRFDDGLTPETAATLVDG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCEEEEECCCCCCHHHHHHHCC
AWQDVTVPHTWNRLGEYRIGRTAATDNRQGKGWYRLRVNGAALPAGKRHIIEFEAVGNLA
CCCCCCCCHHHHHHCCCCCCCEECCCCCCCCCEEEEEECCEECCCCCEEEEEEHHCCCHH
DLWVNGRHVGRHAGAFSRFRFDLTDFLNPADPNIILLRADNSMPGPGSSTEHIIPLDGDF
HHEECCCCCCCCCCCHHHEEEEHHHHCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCE
FIHGGPYRPARLLHVAPSHIALDDHGGPGVYATPTIKDGAGQVAIRVRLTDIAAGQSLVA
EEECCCCCCEEEEEECCCEEEEECCCCCCEEECCCCCCCCCEEEEEEEEEECCCCHHHHH
TLRDAGGRTVAEGTRPLTAGQREAALTLDVAAPRRWNGRADPYRYRLETRLADTGGTLDS
HHHHCCCCEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCE
VTVPVGFRAFRFDAATGFYLNGKHLPLHGVSRHQDYLGKGWALSAEDHARDMALIAEMGA
EEECCCEEEEEEECCCEEEECCCCCCCCCCCHHHHHCCCCEEECCHHHHHHHHHHHHCCC
NTVRFAHYQHAADWFDLADRFGMIVWAELPFVNKPSHGDAPASPELVANARQQMIELIRQ
CEEEEEHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
NYNHPSVVTWGIGNEVDMDMAFGRMGPKADARPLLRELHALSKAEDPSRPTVIADCCELT
CCCCCCEEEECCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEHHHHHCC
PAKKPDYQPPLTGEADLMGYNRYYGWYYGEVSDLGPHLDALHAKYPSVPISVSEYGAGGA
CCCCCCCCCCCCCCHHEEECCCCCCEEECCHHHCCCCHHHHHHCCCCCCEEHHCCCCCCC
LSQHVEDPAHHPINPGGRPHPEEFQSWLHEQSWPQLRDRRYLWASWIWNMFDFSSKIRKE
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCEEEHHHHHHHHHHHHHHHHCC
GDATDINDKGLVTFDRKVKKDAFFYYKAQWSTEPVVHITSRRWTTRASPVTAIKVYSNAP
CCCCCCCCCCEEEECCHHCCCEEEEEEEECCCCCEEEEECCCEECCCCCEEEEEEECCCC
AVTLTFNGVPLGEVACADRICTLDNIVLRPGDNVVTARATFASGVVKDEVRWTLTPL
EEEEEECCCCCCHHHHHHHHCCCCCEEECCCCCEEEEEHHHHCCCEECCCEEEECCC
>Mature Secondary Structure 
PRCLTMLFAAMLAACSAAPRPTPAAAPPFTRDTTELTHGWQFRFDDGLTPETAATLVDG
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCEEEEECCCCCCHHHHHHHCC
AWQDVTVPHTWNRLGEYRIGRTAATDNRQGKGWYRLRVNGAALPAGKRHIIEFEAVGNLA
CCCCCCCCHHHHHHCCCCCCCEECCCCCCCCCEEEEEECCEECCCCCEEEEEEHHCCCHH
DLWVNGRHVGRHAGAFSRFRFDLTDFLNPADPNIILLRADNSMPGPGSSTEHIIPLDGDF
HHEECCCCCCCCCCCHHHEEEEHHHHCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCE
FIHGGPYRPARLLHVAPSHIALDDHGGPGVYATPTIKDGAGQVAIRVRLTDIAAGQSLVA
EEECCCCCCEEEEEECCCEEEEECCCCCCEEECCCCCCCCCEEEEEEEEEECCCCHHHHH
TLRDAGGRTVAEGTRPLTAGQREAALTLDVAAPRRWNGRADPYRYRLETRLADTGGTLDS
HHHHCCCCEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCE
VTVPVGFRAFRFDAATGFYLNGKHLPLHGVSRHQDYLGKGWALSAEDHARDMALIAEMGA
EEECCCEEEEEEECCCEEEECCCCCCCCCCCHHHHHCCCCEEECCHHHHHHHHHHHHCCC
NTVRFAHYQHAADWFDLADRFGMIVWAELPFVNKPSHGDAPASPELVANARQQMIELIRQ
CEEEEEHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
NYNHPSVVTWGIGNEVDMDMAFGRMGPKADARPLLRELHALSKAEDPSRPTVIADCCELT
CCCCCCEEEECCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEHHHHHCC
PAKKPDYQPPLTGEADLMGYNRYYGWYYGEVSDLGPHLDALHAKYPSVPISVSEYGAGGA
CCCCCCCCCCCCCCHHEEECCCCCCEEECCHHHCCCCHHHHHHCCCCCCEEHHCCCCCCC
LSQHVEDPAHHPINPGGRPHPEEFQSWLHEQSWPQLRDRRYLWASWIWNMFDFSSKIRKE
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCEEEHHHHHHHHHHHHHHHHCC
GDATDINDKGLVTFDRKVKKDAFFYYKAQWSTEPVVHITSRRWTTRASPVTAIKVYSNAP
CCCCCCCCCCEEEECCHHCCCEEEEEEEECCCCCEEEEECCCEECCCCCEEEEEEECCCC
AVTLTFNGVPLGEVACADRICTLDNIVLRPGDNVVTARATFASGVVKDEVRWTLTPL
EEEEEECCCCCCHHHHHHHHCCCCCEEECCCCCEEEEEHHHHCCCEECCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA