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The map label for this gene is paaF [C]

Identifier: 103486368

GI number: 103486368

Start: 884626

End: 885405

Strand: Reverse

Name: paaF [C]

Synonym: Sala_0878

Alternate gene names: 103486368

Gene position: 885405-884626 (Counterclockwise)

Preceding gene: 103486378

Following gene: 103486367

Centisome position: 26.47

GC content: 63.46

Gene sequence:

>780_bases
GTGTCCGAAATGGTCCTGAGCGAGCGCGAGGGTGCCCTGCGCATCCTGACGCTGAACCGCGCCGAGCGGCACAATGCGAT
GGACGATGCCATGTCGGCGCTGTTTCAGCGCCTGCTTGGCGAGGCACTTGACGAAGACACCACAAATGCCGTGCTGATCC
GCGCGGCGGGCAAGAGCTTTTGCTCTGGCCGCGATACCAGCGTGCTGGGCCATCGGGCGCGCGATGAAAGCGATTTTCAT
TTCGTCCGCCGCGCCCAGGAAGGACGCCTGCGTATGCAGGAATCGACCAAGCCGATCGTCGCTGCGCTCAAGGGGGGCGT
TATCGGCGGCGGGTGCGAACTGGCACTCGCCGCCGATATTCGGGTGGCCGATACGACGCTGAAAATGGCCTTGCCGGAGA
TTTTATATGGCGTGTTGCCCGATACCGGGGGGACGCAGATGATGACCGCGCTGGTGGGTCCGTCGCGAACCAAATATCTG
GTGTTGACCGGACGCCCCATCGACGCCGCAACCGCGCTGGAATGGGGTGCGGTCGATTTCGTTGTCTCGCCCGAAGAACT
GGACGCAAGGGCGCTGGACATCGCCCGCGACATAGCCGCCAAACCGCCGATCAATCTGGCGATGGGCAAGGAGATGATCA
ACCTGATGCACGGCCCCGCGATCCGCACCGGGACGCGCGCCGAGCTTTATGCGCAAAGCTATCTGTTCCAGACCGAAGAT
TATCGGGAAGCCCGCACGGCGCTGCGCGAACGGCGCCAACCCCGGTACAGGGGGAAATAG

Upstream 100 bases:

>100_bases
GCTCAACTCCATCGCGATGACTCTCCCCGATCGTTTCAACATAATTGACTTAGTTATATAACTCGTGCAAGCCCTGTCGG
AAAGAAATTGGGAGCGGCAA

Downstream 100 bases:

>100_bases
CATGGCGCTGCCCGCCCCGCCCCCGCTCGGTGCCAAGGCGCTGCCCGACGGCACCTATGCGGGCCAGGTCGTGGCCGTTA
CCGGCGGGGGCACCGGGCTG

Product: response regulator receiver protein

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSEMVLSEREGALRILTLNRAERHNAMDDAMSALFQRLLGEALDEDTTNAVLIRAAGKSFCSGRDTSVLGHRARDESDFH
FVRRAQEGRLRMQESTKPIVAALKGGVIGGGCELALAADIRVADTTLKMALPEILYGVLPDTGGTQMMTALVGPSRTKYL
VLTGRPIDAATALEWGAVDFVVSPEELDARALDIARDIAAKPPINLAMGKEMINLMHGPAIRTGTRAELYAQSYLFQTED
YREARTALRERRQPRYRGK

Sequences:

>Translated_259_residues
MSEMVLSEREGALRILTLNRAERHNAMDDAMSALFQRLLGEALDEDTTNAVLIRAAGKSFCSGRDTSVLGHRARDESDFH
FVRRAQEGRLRMQESTKPIVAALKGGVIGGGCELALAADIRVADTTLKMALPEILYGVLPDTGGTQMMTALVGPSRTKYL
VLTGRPIDAATALEWGAVDFVVSPEELDARALDIARDIAAKPPINLAMGKEMINLMHGPAIRTGTRAELYAQSYLFQTED
YREARTALRERRQPRYRGK
>Mature_258_residues
SEMVLSEREGALRILTLNRAERHNAMDDAMSALFQRLLGEALDEDTTNAVLIRAAGKSFCSGRDTSVLGHRARDESDFHF
VRRAQEGRLRMQESTKPIVAALKGGVIGGGCELALAADIRVADTTLKMALPEILYGVLPDTGGTQMMTALVGPSRTKYLV
LTGRPIDAATALEWGAVDFVVSPEELDARALDIARDIAAKPPINLAMGKEMINLMHGPAIRTGTRAELYAQSYLFQTEDY
REARTALRERRQPRYRGK

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=259, Percent_Identity=30.1158301158301, Blast_Score=117, Evalue=8e-27,
Organism=Homo sapiens, GI20127408, Length=179, Percent_Identity=32.4022346368715, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4502327, Length=261, Percent_Identity=30.2681992337165, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI68989263, Length=178, Percent_Identity=30.8988764044944, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI37594469, Length=205, Percent_Identity=28.780487804878, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI37594471, Length=205, Percent_Identity=28.780487804878, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI70995211, Length=271, Percent_Identity=28.7822878228782, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI31542718, Length=249, Percent_Identity=24.8995983935743, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI221136756, Length=214, Percent_Identity=23.8317757009346, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI221136753, Length=214, Percent_Identity=23.8317757009346, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI221307494, Length=214, Percent_Identity=23.8317757009346, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787659, Length=261, Percent_Identity=30.6513409961686, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787660, Length=265, Percent_Identity=32.8301886792453, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI221142681, Length=264, Percent_Identity=30.6818181818182, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87082183, Length=254, Percent_Identity=28.3464566929134, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788682, Length=155, Percent_Identity=31.6129032258064, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1788597, Length=254, Percent_Identity=26.7716535433071, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790281, Length=165, Percent_Identity=30.3030303030303, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=235, Percent_Identity=31.063829787234, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17554946, Length=260, Percent_Identity=28.0769230769231, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25145438, Length=257, Percent_Identity=29.5719844357977, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17508951, Length=223, Percent_Identity=31.8385650224215, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17560910, Length=211, Percent_Identity=27.4881516587678, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI25144276, Length=223, Percent_Identity=31.8385650224215, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17508953, Length=216, Percent_Identity=31.9444444444444, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17558304, Length=220, Percent_Identity=30.4545454545455, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17534483, Length=257, Percent_Identity=24.5136186770428, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536985, Length=230, Percent_Identity=26.0869565217391, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25144160, Length=190, Percent_Identity=30.5263157894737, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25144157, Length=190, Percent_Identity=30.5263157894737, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25141363, Length=197, Percent_Identity=25.3807106598985, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=195, Percent_Identity=30.2564102564103, Blast_Score=92, Evalue=6e-20,
Organism=Drosophila melanogaster, GI20129971, Length=243, Percent_Identity=29.2181069958848, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24653477, Length=243, Percent_Identity=29.2181069958848, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24653139, Length=266, Percent_Identity=29.3233082706767, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI21357171, Length=241, Percent_Identity=26.1410788381743, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24650670, Length=215, Percent_Identity=29.7674418604651, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19922422, Length=262, Percent_Identity=25.1908396946565, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19921000, Length=207, Percent_Identity=32.3671497584541, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583077, Length=207, Percent_Identity=32.3671497584541, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583079, Length=207, Percent_Identity=32.3671497584541, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24654903, Length=212, Percent_Identity=22.6415094339623, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28460; Mature: 28329

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEMVLSEREGALRILTLNRAERHNAMDDAMSALFQRLLGEALDEDTTNAVLIRAAGKSF
CCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHH
CSGRDTSVLGHRARDESDFHFVRRAQEGRLRMQESTKPIVAALKGGVIGGGCELALAADI
CCCCCCHHHCCCCCCCCHHHHHHHHHHCCEEEHHCCCHHHHHHHCCEEECCCEEEEEECE
RVADTTLKMALPEILYGVLPDTGGTQMMTALVGPSRTKYLVLTGRPIDAATALEWGAVDF
EEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHCCCCEEE
VVSPEELDARALDIARDIAAKPPINLAMGKEMINLMHGPAIRTGTRAELYAQSYLFQTED
EECHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHH
YREARTALRERRQPRYRGK
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SEMVLSEREGALRILTLNRAERHNAMDDAMSALFQRLLGEALDEDTTNAVLIRAAGKSF
CCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHH
CSGRDTSVLGHRARDESDFHFVRRAQEGRLRMQESTKPIVAALKGGVIGGGCELALAADI
CCCCCCHHHCCCCCCCCHHHHHHHHHHCCEEEHHCCCHHHHHHHCCEEECCCEEEEEECE
RVADTTLKMALPEILYGVLPDTGGTQMMTALVGPSRTKYLVLTGRPIDAATALEWGAVDF
EEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHCCCCEEE
VVSPEELDARALDIARDIAAKPPINLAMGKEMINLMHGPAIRTGTRAELYAQSYLFQTED
EECHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHH
YREARTALRERRQPRYRGK
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA