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The map label for this gene is cysH [H]

Identifier: 103486260

GI number: 103486260

Start: 775176

End: 775982

Strand: Reverse

Name: cysH [H]

Synonym: Sala_0768

Alternate gene names: 103486260

Gene position: 775982-775176 (Counterclockwise)

Preceding gene: 103486261

Following gene: 103486259

Centisome position: 23.2

GC content: 65.06

Gene sequence:

>807_bases
ATGGGCATCTCGACTTCGCTCGATGCGAACGGAATTGGGAATGATCGTCGGCGCGACCGCATCGACGTCGCGCCGCGCTT
CACCCAGGCGGACGTCATCCGCCTCAACAACCTTTTCCGCGGCCAGGACGCCGCCGAGGTCGTCGCGAGTGTGATCGGCG
CCGGTTTGCTCGGCGAGACGGCGATCGTGTCGAGCTTCGGCGCCGAAAGCGCGGTGCTGCTCCATCTTGTCAGCCGCGTT
GCGCCCGACATGCCGGTGCTTTTCCTCGATACCGGCAAGCATTTCCCCGAAACGCTCGCCTATCGCGACGAACTGGCGGC
GCAGCTGGGGCTCAATATCGTCAATCTGACGCCCGATCCCGACGAACTGGCAAAAAAGGACGCCACCGAGCTTCGCTGGT
CGTACGATCCCGACGGCTGCTGCGAAATCCGCAAGGTAAAGCCGCTCGAAAAGGCGCTGACCGATTTCGACACGTCGATC
ACCGGCCGCAAGGGCTTTCAGTCGGCGACGCGGCAGGGCTTGCCGCGCTTCGAACTCGACGGAACCACCGGCCGCCTGAA
GTTCAATCCACTCGCCAACTGGACGCGCGAGATGCTCGACGCCTATTTCGCCGAGCACGACCTGCCGCGCCATCCGCTGG
AAGCGCAAGGCTATCCCTCGATCGGCTGTTCGCCCTGCACGTCGAAGGTGAAGCCGGGCGAAGACCCGCGCTCGGGCCGC
TGGCGCGGCTGGGACAAGACCGAATGCGGCATCCACGAAGCGGTGACGCCGCTGGGCGACGATCCGGCGAACGACCCGGC
GTTTTGA

Upstream 100 bases:

>100_bases
GGCGCGGTGCCGATATGGAAATTAAGGCATGGCTAAACCTGATCCTAAAATCCCGTTCGTGTCGAGCGAAGTCGAGACAC
CGAGAGGGCATGCACCCACG

Downstream 100 bases:

>100_bases
GTAAACGTCATCCCAGCGAAAGCTGGGATCGCTGGCCATCTTGCGCTACGCTGTCAGCATGGGCCGGGGCGGATATGTCT
ATATTATGACCAACAAACGT

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MGISTSLDANGIGNDRRRDRIDVAPRFTQADVIRLNNLFRGQDAAEVVASVIGAGLLGETAIVSSFGAESAVLLHLVSRV
APDMPVLFLDTGKHFPETLAYRDELAAQLGLNIVNLTPDPDELAKKDATELRWSYDPDGCCEIRKVKPLEKALTDFDTSI
TGRKGFQSATRQGLPRFELDGTTGRLKFNPLANWTREMLDAYFAEHDLPRHPLEAQGYPSIGCSPCTSKVKPGEDPRSGR
WRGWDKTECGIHEAVTPLGDDPANDPAF

Sequences:

>Translated_268_residues
MGISTSLDANGIGNDRRRDRIDVAPRFTQADVIRLNNLFRGQDAAEVVASVIGAGLLGETAIVSSFGAESAVLLHLVSRV
APDMPVLFLDTGKHFPETLAYRDELAAQLGLNIVNLTPDPDELAKKDATELRWSYDPDGCCEIRKVKPLEKALTDFDTSI
TGRKGFQSATRQGLPRFELDGTTGRLKFNPLANWTREMLDAYFAEHDLPRHPLEAQGYPSIGCSPCTSKVKPGEDPRSGR
WRGWDKTECGIHEAVTPLGDDPANDPAF
>Mature_267_residues
GISTSLDANGIGNDRRRDRIDVAPRFTQADVIRLNNLFRGQDAAEVVASVIGAGLLGETAIVSSFGAESAVLLHLVSRVA
PDMPVLFLDTGKHFPETLAYRDELAAQLGLNIVNLTPDPDELAKKDATELRWSYDPDGCCEIRKVKPLEKALTDFDTSIT
GRKGFQSATRQGLPRFELDGTTGRLKFNPLANWTREMLDAYFAEHDLPRHPLEAQGYPSIGCSPCTSKVKPGEDPRSGRW
RGWDKTECGIHEAVTPLGDDPANDPAF

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=254, Percent_Identity=33.4645669291339, Blast_Score=115, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6325425, Length=231, Percent_Identity=35.0649350649351, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 29347; Mature: 29216

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGISTSLDANGIGNDRRRDRIDVAPRFTQADVIRLNNLFRGQDAAEVVASVIGAGLLGET
CCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
AIVSSFGAESAVLLHLVSRVAPDMPVLFLDTGKHFPETLAYRDELAAQLGLNIVNLTPDP
HHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEECCCCH
DELAKKDATELRWSYDPDGCCEIRKVKPLEKALTDFDTSITGRKGFQSATRQGLPRFELD
HHHHHCCHHHCCCCCCCCCCHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEC
GTTGRLKFNPLANWTREMLDAYFAEHDLPRHPLEAQGYPSIGCSPCTSKVKPGEDPRSGR
CCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
WRGWDKTECGIHEAVTPLGDDPANDPAF
CCCCCCCCCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
GISTSLDANGIGNDRRRDRIDVAPRFTQADVIRLNNLFRGQDAAEVVASVIGAGLLGET
CCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
AIVSSFGAESAVLLHLVSRVAPDMPVLFLDTGKHFPETLAYRDELAAQLGLNIVNLTPDP
HHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEECCCCH
DELAKKDATELRWSYDPDGCCEIRKVKPLEKALTDFDTSITGRKGFQSATRQGLPRFELD
HHHHHCCHHHCCCCCCCCCCHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEC
GTTGRLKFNPLANWTREMLDAYFAEHDLPRHPLEAQGYPSIGCSPCTSKVKPGEDPRSGR
CCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
WRGWDKTECGIHEAVTPLGDDPANDPAF
CCCCCCCCCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]