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The map label for this gene is 103486253

Identifier: 103486253

GI number: 103486253

Start: 769296

End: 770468

Strand: Reverse

Name: 103486253

Synonym: Sala_0761

Alternate gene names: NA

Gene position: 770468-769296 (Counterclockwise)

Preceding gene: 103486254

Following gene: 103486252

Centisome position: 23.03

GC content: 66.58

Gene sequence:

>1173_bases
ATGGCCAGCGCACGCGATCTCGACATCATCGTTTATGGCGCCACCGGATTCACCGGCCGCCTCGTCGCCGAATATCTCGC
GCACCACTACAAGGACCGCAAGGATGCGCCCAAATGGGCGATGGCGGGGCGCAGCCTTGTCAAACTCGCCGAGGTGCGCG
ACCTGGTCGGCGCGCCCGCCGACACGCCGCTGATCGTCGCCGACGCCAGCGATCGCGCGAGCCTCGACGCGATGGCGGCG
CGGACGCAGGTGGTGCTGACCACCGTCGGTCCCTATCAGCTATACGGCAGCGATCTCGTCGCCGCGTGCGTCCGCGCGGG
CACCGCCTATGCCGACCTGTGCGGCGAGCCCGGCTGGATGCGCGAGATGATCGACGCGCACGAAGATGCGGCAAAGGCAT
CGGGCGCGCGGATCACCTTCAGCTGCGGATTCGACTCGATCCCCTTCGACCTCGGCGTATTGTTCCTTCAGGAGGAGGCG
GTGCGCCGCCACGGCAAGCCCGCGCCACGGGTCAAGGGCCGCGTGCGCAAGATGGCGGGCGGCGCGTCGGGCGGCACGAT
CGCCAGCCTGACCGAGACGTTGAAAGCCGTCGCGAAAAAGCCGTCGCTCGCGCTGCTGCTCAAATCCTCCTTTGCACTCA
CGCCCGGCTTCGAGGGTCCGGCGCAGCCAAGCGGGCTGATCCCCGAATATGACGGGGCGACGGGCACCTGGACCGCGCCC
TTCGTCATGGCGCCGATCAACACCAAAAATGTCCACCGCACCAATTATCTGCTCGGCCACAAATGGGGCGCCGACCTCGT
CTATGACGAGATGGTGATGACGACGATCGGCGACGCGGGCAAGGCGATGGCCGAAGCGATGGCCAAGGCCAATCCGTTCG
GCGATTCCAAGCTCCGGCCCGGCGAAGGCCCGAGCAAGGAGGAGCGCGAAAACGGCTTTTACGACATCCTGTTCATCGGC
GAATATCCCGACGGCACGACGCTGCGCGCCAGCGTGCAGGGCGACCGCGACCCCGGCTATGGCTCGACATCGAAGATGCT
TGCCGAAACGGGCATGGCATTGCTTGAGAACAAGGGCGCGGGCGGCGTATGGACGCCGGGCGCGCTGCTTGGCCAGGCGC
TGATCGACCGGCTGACTGCCAACGCCGGACTGACCTTTCAGATCGAGGAATGA

Upstream 100 bases:

>100_bases
GCCTTTCGGTTGCCGATTCCGTCATGGCCCCCGCCCCCCTTGGCACCGCCCTCCATCTGCGCTAGCCTCCACTTGACGTT
TACGTAAAGGGAGAGGCTCG

Downstream 100 bases:

>100_bases
CAACAGAATGACGACCTCTCCCGGCGCGCTCGACGCGCTGCTCGCGACGCTGCGCACCGAAGAGGGCGTGGCCAAGGCGC
ATATCGACGAAGGCTGGATG

Product: saccharopine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MASARDLDIIVYGATGFTGRLVAEYLAHHYKDRKDAPKWAMAGRSLVKLAEVRDLVGAPADTPLIVADASDRASLDAMAA
RTQVVLTTVGPYQLYGSDLVAACVRAGTAYADLCGEPGWMREMIDAHEDAAKASGARITFSCGFDSIPFDLGVLFLQEEA
VRRHGKPAPRVKGRVRKMAGGASGGTIASLTETLKAVAKKPSLALLLKSSFALTPGFEGPAQPSGLIPEYDGATGTWTAP
FVMAPINTKNVHRTNYLLGHKWGADLVYDEMVMTTIGDAGKAMAEAMAKANPFGDSKLRPGEGPSKEERENGFYDILFIG
EYPDGTTLRASVQGDRDPGYGSTSKMLAETGMALLENKGAGGVWTPGALLGQALIDRLTANAGLTFQIEE

Sequences:

>Translated_390_residues
MASARDLDIIVYGATGFTGRLVAEYLAHHYKDRKDAPKWAMAGRSLVKLAEVRDLVGAPADTPLIVADASDRASLDAMAA
RTQVVLTTVGPYQLYGSDLVAACVRAGTAYADLCGEPGWMREMIDAHEDAAKASGARITFSCGFDSIPFDLGVLFLQEEA
VRRHGKPAPRVKGRVRKMAGGASGGTIASLTETLKAVAKKPSLALLLKSSFALTPGFEGPAQPSGLIPEYDGATGTWTAP
FVMAPINTKNVHRTNYLLGHKWGADLVYDEMVMTTIGDAGKAMAEAMAKANPFGDSKLRPGEGPSKEERENGFYDILFIG
EYPDGTTLRASVQGDRDPGYGSTSKMLAETGMALLENKGAGGVWTPGALLGQALIDRLTANAGLTFQIEE
>Mature_389_residues
ASARDLDIIVYGATGFTGRLVAEYLAHHYKDRKDAPKWAMAGRSLVKLAEVRDLVGAPADTPLIVADASDRASLDAMAAR
TQVVLTTVGPYQLYGSDLVAACVRAGTAYADLCGEPGWMREMIDAHEDAAKASGARITFSCGFDSIPFDLGVLFLQEEAV
RRHGKPAPRVKGRVRKMAGGASGGTIASLTETLKAVAKKPSLALLLKSSFALTPGFEGPAQPSGLIPEYDGATGTWTAPF
VMAPINTKNVHRTNYLLGHKWGADLVYDEMVMTTIGDAGKAMAEAMAKANPFGDSKLRPGEGPSKEERENGFYDILFIGE
YPDGTTLRASVQGDRDPGYGSTSKMLAETGMALLENKGAGGVWTPGALLGQALIDRLTANAGLTFQIEE

Specific function: Unknown

COG id: COG3268

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770836, Length=164, Percent_Identity=38.4146341463415, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17560066, Length=426, Percent_Identity=26.9953051643192, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32567112, Length=157, Percent_Identity=41.4012738853503, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71991033, Length=424, Percent_Identity=27.3584905660377, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24646278, Length=433, Percent_Identity=28.6374133949192, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24644140, Length=158, Percent_Identity=36.7088607594937, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24644142, Length=158, Percent_Identity=36.7088607594937, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21356081, Length=158, Percent_Identity=36.7088607594937, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: NA

Molecular weight: Translated: 41333; Mature: 41202

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASARDLDIIVYGATGFTGRLVAEYLAHHYKDRKDAPKWAMAGRSLVKLAEVRDLVGAPA
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
DTPLIVADASDRASLDAMAARTQVVLTTVGPYQLYGSDLVAACVRAGTAYADLCGEPGWM
CCCEEEECCCCCHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHH
REMIDAHEDAAKASGARITFSCGFDSIPFDLGVLFLQEEAVRRHGKPAPRVKGRVRKMAG
HHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
GASGGTIASLTETLKAVAKKPSLALLLKSSFALTPGFEGPAQPSGLIPEYDGATGTWTAP
CCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECC
FVMAPINTKNVHRTNYLLGHKWGADLVYDEMVMTTIGDAGKAMAEAMAKANPFGDSKLRP
EEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCC
GEGPSKEERENGFYDILFIGEYPDGTTLRASVQGDRDPGYGSTSKMLAETGMALLENKGA
CCCCCHHHHCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
GGVWTPGALLGQALIDRLTANAGLTFQIEE
CCCCCCHHHHHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure 
ASARDLDIIVYGATGFTGRLVAEYLAHHYKDRKDAPKWAMAGRSLVKLAEVRDLVGAPA
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
DTPLIVADASDRASLDAMAARTQVVLTTVGPYQLYGSDLVAACVRAGTAYADLCGEPGWM
CCCEEEECCCCCHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHH
REMIDAHEDAAKASGARITFSCGFDSIPFDLGVLFLQEEAVRRHGKPAPRVKGRVRKMAG
HHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
GASGGTIASLTETLKAVAKKPSLALLLKSSFALTPGFEGPAQPSGLIPEYDGATGTWTAP
CCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECC
FVMAPINTKNVHRTNYLLGHKWGADLVYDEMVMTTIGDAGKAMAEAMAKANPFGDSKLRP
EEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCC
GEGPSKEERENGFYDILFIGEYPDGTTLRASVQGDRDPGYGSTSKMLAETGMALLENKGA
CCCCCHHHHCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
GGVWTPGALLGQALIDRLTANAGLTFQIEE
CCCCCCHHHHHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]